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Rohan Khera, MD, MS

Assistant Professor of Medicine (Cardiovascular Medicine) and of Biostatistics (Health Informatics); Clinical Director, Center for Health Informatics and Analytics, YNHH/Yale Center for Outcomes Research & Evaluation (CORE)

Contact Information

Rohan Khera, MD, MS

Email
rohan.khera@yale.edu

Lab Location

195 Church Street
Fl 6th
New Haven, CT 06510

Office Location

Center for Outcomes Research and Evaluation
195 Church Street, Fl 5th Floor
New Haven, CT 06510

Mailing Address

Cardiovascular Data Science Lab (CarDS)
300 George St
New Haven, Connecticut 06510
United States

CarDS Lab

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Research Summary

Dr. Khera is leading the development and implementation of strategies to improve outcomes of patients with or at-risk for cardiovascular disease through data-driven innovations in delivering evidence-based, patient-centered care. His work focuses on novel strategies to learn from complex clinical data and incorporates information and technology in healthcare to improve care efficiency and provide actionable insights to improve patient outcomes. He pursues this work as the Principal Investigator of the Cardiovascular Data Science (CarDS) Lab at the Yale School of Medicine. The work he has led has been published in JAMA, BMJ, Circulation, JAMA Internal Medicine, Journal of the American College of Cardiology, and JAMA Cardiology, among others.

Extensive Research Description

Dr. Khera's clinical observations have informed my research, which has been featured in leading medical and cardiovascular journals.

First, he has pursued data-driven strategies to evaluate the quality of care measures and their association with patient outcomes in those hospitalized with cardiovascular disease.
Second, he and his team have developed novel strategies that employ machine learning to infer personalized effect estimates from clinical trials using computational phenomaps.
Third, he has led the application of deep learning and artificial intelligence to electrocardiography and cardiac imaging.
Fourth, he has led the development of data-driven quality measurement programs in cardiovascular diseases in large national datasets.
Finally, he has conducted methodological investigations that focus on improving the rigor of studies that use large datasets.

A key focus of his ongoing work is digital phenotyping of cardiovascular disease and the development of automated assays of care quality within the electronic health record. The work is specifically designing and implementing clinical decision support with a mixed quantitative-qualitative research methodology that incorporates inputs from patients and clinicians in retrieving information and designing interventions. His group has developed a series of applications of machine learning to clinical data. These tools have been validated in multinational populations and are designed to increase efficiency and personalization of care.

Coauthors

Research Interests

Artificial Intelligence; Cardiovascular Diseases; Health Care Quality, Access, and Evaluation; Machine Learning; Health Equity; Data Science

Selected Publications

Nonexercise machine learning models for maximal oxygen uptake prediction in national population surveys.Liu Y, Herrin J, Huang C, Khera R, Dhingra L, Dong W, Mortazavi B, Krumholz H, Lu Y. Nonexercise machine learning models for maximal oxygen uptake prediction in national population surveys. Journal Of The American Medical Informatics Association 2023 PMID: 36905605, DOI: 10.1093/jamia/ocad035.
Quantifying Blood Pressure Visit-to-Visit Variability in the Real-World Setting: A Retrospective Cohort Study.Lu Y, Linderman G, Mahajan S, Liu Y, Huang C, Khera R, Mortazavi B, Spatz E, Krumholz H. Quantifying Blood Pressure Visit-to-Visit Variability in the Real-World Setting: A Retrospective Cohort Study. Circulation Cardiovascular Quality And Outcomes 2023, e009258. PMID: 36883456, DOI: 10.1161/circoutcomes.122.009258.
A MACHINE LEARNING-GUIDED APPROACH FOR ADAPTIVE TRIAL ENRICHMENT AND ACCELERATION OF CARDIOVASCULAR OUTCOME TRIALS: INSIGHTS FROM THE SPRINT AND ACCORD-BP TRIALSOikonomou E, Spatz E, Ross J, Suchard M, Krumholz H, Khera R. A MACHINE LEARNING-GUIDED APPROACH FOR ADAPTIVE TRIAL ENRICHMENT AND ACCELERATION OF CARDIOVASCULAR OUTCOME TRIALS: INSIGHTS FROM THE SPRINT AND ACCORD-BP TRIALS Journal Of The American College Of Cardiology 2023, 81: 2314. DOI: 10.1016/s0735-1097(23)02758-4.
SEX DIFFERENCE IN CAUSES AND TIMING OF ONE-YEAR OUTCOMES AMONG YOUNG ACUTE MYOCARDIAL INFARCTION PATIENTS; RESULTS FROM THE VIRGO STUDYSawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. SEX DIFFERENCE IN CAUSES AND TIMING OF ONE-YEAR OUTCOMES AMONG YOUNG ACUTE MYOCARDIAL INFARCTION PATIENTS; RESULTS FROM THE VIRGO STUDY Journal Of The American College Of Cardiology 2023, 81: 1294. DOI: 10.1016/s0735-1097(23)01738-2.
MULTINATIONAL PATTERNS OF SECOND-LINE ANTI-HYPERGLYCEMIC DRUG INITIATION IN ESTABLISHED CARDIOVASCULAR DISEASE: A FEDERATED PHARMACOEPIDEMIOLOGIC EVALUATION IN LEGEND-T2DMKhera R, Dhingra L, Li K, Aminorroaya A, Zhou J, Arshad F, Bu F, Dorr D, Falconer T, French T, Lau W, Lu Y, Man K, Matheny M, Minty E, Nishimura A, Ostropolets A, Seager S, Y.F. W, Yang J, Yin C, Hripcsak G, Krumholz H. MULTINATIONAL PATTERNS OF SECOND-LINE ANTI-HYPERGLYCEMIC DRUG INITIATION IN ESTABLISHED CARDIOVASCULAR DISEASE: A FEDERATED PHARMACOEPIDEMIOLOGIC EVALUATION IN LEGEND-T2DM Journal Of The American College Of Cardiology 2023, 81: 1646. DOI: 10.1016/s0735-1097(23)02090-9.
DEEP LEARNING-BASED IDENTIFICATION OF HEART FAILURE WITH REDUCED EJECTION FRACTION IN CLINICAL DOCUMENTATION TO AUTOMATE CARE QUALITY ASSESSMENT IN HEART FAILURENargesi A, Rosand B, Hengartner A, Adejumo P, Khera R. DEEP LEARNING-BASED IDENTIFICATION OF HEART FAILURE WITH REDUCED EJECTION FRACTION IN CLINICAL DOCUMENTATION TO AUTOMATE CARE QUALITY ASSESSMENT IN HEART FAILURE Journal Of The American College Of Cardiology 2023, 81: 2302. DOI: 10.1016/s0735-1097(23)02746-8.
DEEP LEARNING-BASED DETECTION OF LEFT VENTRICULAR SYSTOLIC DYSFUNCTION FROM NOISY SINGLE LEAD ELECTROCARDIOGRAPHY ADAPTED FOR WEARABLE DEVICESKhunte A, Sangha V, Dhingra L, Oikonomou E, Mortazavi B, Khera R. DEEP LEARNING-BASED DETECTION OF LEFT VENTRICULAR SYSTOLIC DYSFUNCTION FROM NOISY SINGLE LEAD ELECTROCARDIOGRAPHY ADAPTED FOR WEARABLE DEVICES Journal Of The American College Of Cardiology 2023, 81: 2262. DOI: 10.1016/s0735-1097(23)02706-7.
SMART-AS: A NOVEL ARTIFICIAL INTELLIGENCE TOOL TO DETECT SEVERE AORTIC STENOSIS FROM ELECTROCARDIOGRAPHIC IMAGESSangha V, Oikonomou E, Khunte A, Gupta K, Mortazavi B, Khera R. SMART-AS: A NOVEL ARTIFICIAL INTELLIGENCE TOOL TO DETECT SEVERE AORTIC STENOSIS FROM ELECTROCARDIOGRAPHIC IMAGES Journal Of The American College Of Cardiology 2023, 81: 2409. DOI: 10.1016/s0735-1097(23)02853-x.
BIOMETRIC CONTRASTIVE MODELING FOR DATA-EFFICIENT DEEP LEARNING FROM ELECTROCARDIOGRAPHIC IMAGESSangha V, Khunte A, Holste G, Mortazavi B, Wang Z, Oikonomou E, Khera R. BIOMETRIC CONTRASTIVE MODELING FOR DATA-EFFICIENT DEEP LEARNING FROM ELECTROCARDIOGRAPHIC IMAGES Journal Of The American College Of Cardiology 2023, 81: 2403. DOI: 10.1016/s0735-1097(23)02847-4.
MECHANISTIC EVALUATION OF AN AI-DRIVEN CLINICAL DECISION SUPPORT TOOL TO PERSONALIZE THE USE OF ANATOMICAL TESTING IN SUSPECTED CORONARY ARTERY DISEASEOikonomou E, Suchard M, Miller E, Velazquez E, Khera R. MECHANISTIC EVALUATION OF AN AI-DRIVEN CLINICAL DECISION SUPPORT TOOL TO PERSONALIZE THE USE OF ANATOMICAL TESTING IN SUSPECTED CORONARY ARTERY DISEASE Journal Of The American College Of Cardiology 2023, 81: 1360. DOI: 10.1016/s0735-1097(23)01804-1.
MARKUP ON COMMON GENERIC MEDICATIONS AT HOSPITALS IN THE UNITED STATES: A NATIONALLY REPRESENTATIVE EVALUATIONKhera R, Loccoh E, Nguyen A, Li D, Chase L, Warraich H. MARKUP ON COMMON GENERIC MEDICATIONS AT HOSPITALS IN THE UNITED STATES: A NATIONALLY REPRESENTATIVE EVALUATION Journal Of The American College Of Cardiology 2023, 81: 1667. DOI: 10.1016/s0735-1097(23)02111-3.
Abstract 60: Impact of a Multisite, Protocol-Driven, Nurse Practitioner-Led, Cardiovascular Prevention Program in a Hispanic Medicare Advantage Population at High Risk for ASCVD: Healthy Heart Program at Cano Health.MCCLOSKEY V, Nasir K, Khera R, Oikonomou E, Diaz R, Kenney R, Aguilar R, Gulati M, Cingolani O, Gluckman T, Blankstein R, Hernandez M, Rivera J. Abstract 60: Impact of a Multisite, Protocol-Driven, Nurse Practitioner-Led, Cardiovascular Prevention Program in a Hispanic Medicare Advantage Population at High Risk for ASCVD: Healthy Heart Program at Cano Health. Circulation 2023, 147: a60-a60. DOI: 10.1161/circ.147.suppl_1.60.
Abstract P445: Patterns in Physical Activity Among Individuals With Cardiovascular Risk Factors in the United States: A Population-Based Contemporary Study From NHANES 2017- 2020Nabi W, Aminorroaya A, Khera R. Abstract P445: Patterns in Physical Activity Among Individuals With Cardiovascular Risk Factors in the United States: A Population-Based Contemporary Study From NHANES 2017- 2020 Circulation 2023, 147: ap445-ap445. DOI: 10.1161/circ.147.suppl_1.p445.
Developing Validated Tools to Identify Pulmonary Embolism in Electronic Databases: Rationale and Design of the PE-EHR+ StudyBikdeli B, Lo Y, Khairani C, Bejjani A, Jimenez D, Barco S, Mahajan S, Caraballo C, Secemsky E, Klok F, Hunsaker A, Aghayev A, Muriel A, Wang Y, Hussain M, Appah-Sampong A, Lu Y, Lin Z, Aneja S, Khera R, Goldhaber S, Zhou L, Monreal M, Krumholz H, Piazza G. Developing Validated Tools to Identify Pulmonary Embolism in Electronic Databases: Rationale and Design of the PE-EHR+ Study Thrombosis And Haemostasis 2023 PMID: 36809777, DOI: 10.1055/a-2039-3222.
Timing of Blood Draws Among Patients Hospitalized in a Large Academic Medical CenterCaraballo C, Mahajan S, Murugiah K, Mortazavi B, Lu Y, Khera R, Krumholz H. Timing of Blood Draws Among Patients Hospitalized in a Large Academic Medical Center JAMA 2023, 329: 255-257. PMID: 36648476, PMCID: PMC9856620, DOI: 10.1001/jama.2022.21509.
Hospital Adherence to the Federal Price Transparency Mandate: Results from a Nationally Representative SampleLoccoh E, Khera R, van Meijgaard J, Marsh T, Warraich H. Hospital Adherence to the Federal Price Transparency Mandate: Results from a Nationally Representative Sample Journal Of General Internal Medicine 2023, 1-4. PMID: 36650327, DOI: 10.1007/s11606-023-08039-0.
Unfavorable social determinants of health are associated with higher burden of financial toxicity among patients with atherosclerotic cardiovascular disease in the US: findings from the National Health Interview SurveyValero-Elizondo J, Javed Z, Khera R, Tano M, Dudum R, Acquah I, Hyder A, Andrieni J, Sharma G, Blaha M, Virani S, Blankstein R, Cainzos-Achirica M, Nasir K. Unfavorable social determinants of health are associated with higher burden of financial toxicity among patients with atherosclerotic cardiovascular disease in the US: findings from the National Health Interview Survey Archives Of Public Health 2022, 80: 248. PMID: 36474300, PMCID: PMC9727868, DOI: 10.1186/s13690-022-00987-z.
Time in therapeutic range for targeted temperature management and outcomes following out-of-hospital cardiac arrestWheelock K, Chan P, Chen L, de Lemos J, Miller P, Nallamothu B, Girotra S, Khera R. Time in therapeutic range for targeted temperature management and outcomes following out-of-hospital cardiac arrest Resuscitation 2022, 182: 109650. PMID: 36442596, PMCID: PMC9885789, DOI: 10.1016/j.resuscitation.2022.11.016.
Abstract 15068: Regional Variation in Atrial Fibrillation Ablation Care for Medicare Beneficiaries Across the United StatesHanna J, Freeman J, Hummel J, Curtis J, Lin Z, Akar J, Khera R. Abstract 15068: Regional Variation in Atrial Fibrillation Ablation Care for Medicare Beneficiaries Across the United States Circulation 2022, 146: a15068-a15068. DOI: 10.1161/circ.146.suppl_1.15068.
Abstract 13766: Delays in Care and Outcomes in Out-of-Hospital Cardiac Arrest With Shockable RhythmWheelock K, Miller E, Khera R. Abstract 13766: Delays in Care and Outcomes in Out-of-Hospital Cardiac Arrest With Shockable Rhythm Circulation 2022, 146: a13766-a13766. DOI: 10.1161/circ.146.suppl_1.13766.
Abstract 13661: An Adaptive Strategy of Predictive Enrichment to Increase Efficiency of Randomized Clinical Trials Using Machine Learning: A Simulation of the IRIS TrialOikonomou E, Suchard M, Kernan W, Young L, Inzucchi S, Khera R. Abstract 13661: An Adaptive Strategy of Predictive Enrichment to Increase Efficiency of Randomized Clinical Trials Using Machine Learning: A Simulation of the IRIS Trial Circulation 2022, 146: a13661-a13661. DOI: 10.1161/circ.146.suppl_1.13661.
Abstract 13030: Non-Exercise Machine Learning Model for Maximal Oxygen Uptake Prediction in National Population SurveysLiu Y, Huang C, Mortazavi B, Khera R, Krumholz H, Lu Y. Abstract 13030: Non-Exercise Machine Learning Model for Maximal Oxygen Uptake Prediction in National Population Surveys Circulation 2022, 146: a13030-a13030. DOI: 10.1161/circ.146.suppl_1.13030.
Abstract 14057: Detection of Left Ventricular Systolic Dysfunction From Electrocardiographic ImagesSangha V, Nargesi A, Dhingra L, Mortazavi B, Ribeiro A, Banina E, Brandt C, Miller E, Ribeiro A, Velazquez E, Krumholz H, Khera R. Abstract 14057: Detection of Left Ventricular Systolic Dysfunction From Electrocardiographic Images Circulation 2022, 146: a14057-a14057. DOI: 10.1161/circ.146.suppl_1.14057.
Abstract 13659: Automated Detection of Aortic Stenosis From Single-View 2-Dimensional Echocardiography Using a Semi-Supervised, Contrastive Learning ApproachOikonomou E, Holste G, Mortazavi B, Wang Z, Khera R. Abstract 13659: Automated Detection of Aortic Stenosis From Single-View 2-Dimensional Echocardiography Using a Semi-Supervised, Contrastive Learning Approach Circulation 2022, 146: a13659-a13659. DOI: 10.1161/circ.146.suppl_1.13659.
Abstract 14199: Defining Phenotypic Representativeness of the TOPCAT Trial to a Real-World Electronic Health Record Using Multidimensional PhenomapsThangaraj P, Oikonomou E, Jayaram R, Nargesi A, Suchard M, Khera R. Abstract 14199: Defining Phenotypic Representativeness of the TOPCAT Trial to a Real-World Electronic Health Record Using Multidimensional Phenomaps Circulation 2022, 146: a14199-a14199. DOI: 10.1161/circ.146.suppl_1.14199.
Abstract 15516: A Nationally Representative Evaluation of Patients With Established Cardiovascular Disease and Cardiovascular Risk Factors Achieving Health Goals With Electronic Devices in the United StatesAminorroaya A, Dhingra L, Oikonomou E, Nargesi A, Khera R. Abstract 15516: A Nationally Representative Evaluation of Patients With Established Cardiovascular Disease and Cardiovascular Risk Factors Achieving Health Goals With Electronic Devices in the United States Circulation 2022, 146: a15516-a15516. DOI: 10.1161/circ.146.suppl_1.15516.
Abstract 15333: Use of Wearable Devices by Patients With and At-Risk for Cardiovascular Disease in the United States: A Nationally Representative StudyDhingra L, Aminorroaya A, Oikonomou E, Nargesi A, Khera R. Abstract 15333: Use of Wearable Devices by Patients With and At-Risk for Cardiovascular Disease in the United States: A Nationally Representative Study Circulation 2022, 146: a15333-a15333. DOI: 10.1161/circ.146.suppl_1.15333.
Abstract 10019: Access to Specialty Cardiovascular Care and Uptake of Cardioprotective Anti-Hyperglycemic Agents Among Adults With Type 2 Diabetes: A Cohort StudyNargesi A, Clark C, Liu M, Reddy A, Amodeo S, Khera R. Abstract 10019: Access to Specialty Cardiovascular Care and Uptake of Cardioprotective Anti-Hyperglycemic Agents Among Adults With Type 2 Diabetes: A Cohort Study Circulation 2022, 146: a10019-a10019. DOI: 10.1161/circ.146.suppl_1.10019.
Individualising intensive systolic blood pressure reduction in hypertension using computational trial phenomaps and machine learning: a post-hoc analysis of randomised clinical trialsOikonomou EK, Spatz ES, Suchard MA, Khera R. Individualising intensive systolic blood pressure reduction in hypertension using computational trial phenomaps and machine learning: a post-hoc analysis of randomised clinical trials The Lancet Digital Health 2022, 4: e796-e805. PMID: 36307193, PMCID: PMC9768739, DOI: 10.1016/s2589-7500(22)00170-4.
Variation in coronary angiography use in Out-of-Hospital cardiac arrestAgusala V, Dale P, Khera R, Brown S, Idris A, Link M, Mody P. Variation in coronary angiography use in Out-of-Hospital cardiac arrest Resuscitation 2022, 181: 79-85. PMID: 36332772, DOI: 10.1016/j.resuscitation.2022.10.020.
Contemporary National Patterns of Eligibility and Use of Novel Lipid‐Lowering Therapies in the United StatesShen M, Nargesi A, Nasir K, Bhatt DL, Khera R. Contemporary National Patterns of Eligibility and Use of Novel Lipid‐Lowering Therapies in the United States Journal Of The American Heart Association 2022, 11: e026075. PMID: 36102276, PMCID: PMC9683659, DOI: 10.1161/jaha.122.026075.
Performance of current risk stratification models for predicting mortality in patients with heart failure: a systematic review and meta-analysis.Siddiqi TJ, Ahmed A, Greene SJ, Shahid I, Usman MS, Oshunbade A, Alkhouli M, Hall ME, Murad MH, Khera R, Jain V, Van Spall HGC, Khan MS. Performance of current risk stratification models for predicting mortality in patients with heart failure: a systematic review and meta-analysis. European Journal Of Preventive Cardiology 2022, 29: 2027-2048. PMID: 35919956, DOI: 10.1093/eurjpc/zwac148.
Identifying quality of life outcome patterns to inform treatment choices in ischemic cardiomyopathyMori M, Mark DB, Khera R, Lin H, Jones P, Huang C, Lu Y, Geirsson A, Velazquez EJ, Spertus JA, Krumholz HM. Identifying quality of life outcome patterns to inform treatment choices in ischemic cardiomyopathy American Heart Journal 2022, 254: 12-22. PMID: 35932911, DOI: 10.1016/j.ahj.2022.07.007.
County-level variation in cardioprotective antihyperglycemic prescribing among medicare beneficiariesHanna J, Nargesi AA, Essien UR, Sangha V, Lin Z, Krumholz HM, Khera R. County-level variation in cardioprotective antihyperglycemic prescribing among medicare beneficiaries American Journal Of Preventive Cardiology 2022, 11: 100370. PMID: 35968531, PMCID: PMC9364091, DOI: 10.1016/j.ajpc.2022.100370.
Subjective Financial Hardship due to Medical Bills Among Patients With Heart Failure in the United States: The 2014–2018 Medical Expenditure Panel SurveyAli HR, Valero-Elizondo J, Wang SY, Cainzos-Achirica M, Bhimaraj A, Khan SU, Khan MS, Mossialos E, Khera R, Nasir K. Subjective Financial Hardship due to Medical Bills Among Patients With Heart Failure in the United States: The 2014–2018 Medical Expenditure Panel Survey Journal Of Cardiac Failure 2022, 28: 1424-1433. PMID: 35839928, DOI: 10.1016/j.cardfail.2022.06.009.
Measures of Financial Hardship From Health Care Expenses Among Families With a Member With Atherosclerotic Cardiovascular Disease in the USWang SY, Valero-Elizondo J, Cainzos-Achirica M, Desai NR, Nasir K, Khera R. Measures of Financial Hardship From Health Care Expenses Among Families With a Member With Atherosclerotic Cardiovascular Disease in the US JAMA Health Forum 2022, 3: e221962. PMID: 35977226, PMCID: PMC9308060, DOI: 10.1001/jamahealthforum.2022.1962.
Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world comparative cardiovascular effectiveness and safety studiesKhera R, Schuemie MJ, Lu Y, Ostropolets A, Chen R, Hripcsak G, Ryan PB, Krumholz HM, Suchard MA. Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world comparative cardiovascular effectiveness and safety studies BMJ Open 2022, 12: e057977. PMID: 35680274, PMCID: PMC9185490, DOI: 10.1136/bmjopen-2021-057977.
Rural-Urban Disparities in Heart Failure and Acute Myocardial Infarction HospitalizationsMinhas AMK, Sheikh AB, Ijaz SH, Mostafa A, Nazir S, Khera R, Loccoh EC, Warraich HJ. Rural-Urban Disparities in Heart Failure and Acute Myocardial Infarction Hospitalizations The American Journal Of Cardiology 2022, 175: 164-169. PMID: 35577603, DOI: 10.1016/j.amjcard.2022.04.014.
Short-Term Outcomes After Myopericarditis Related to COVID-19 VaccinationPareek M, Steele J, Asnes J, Baldassarre L, Casale L, Desai N, Elder R, Faherty E, Ferguson I, Fishman R, Ghazizadeh Z, Glick L, Hall E, Khera R, Kokkinidis D, Kwan J, O’Marr J, Schussheim A, Tuohy E, Wang Y, Spatz E, Jacoby D, Miller E. Short-Term Outcomes After Myopericarditis Related to COVID-19 Vaccination JACC Cardiovascular Imaging 2022, 15: 2002-2005. PMCID: PMC9094612, DOI: 10.1016/j.jcmg.2022.03.026.
Short-Term Outcomes After Myopericarditis Related to COVID-19 VaccinationPareek M, Steele J, Asnes J, Baldassarre L, Casale L, Desai N, Elder R, Faherty E, Ferguson I, Fishman R, Ghazizadeh Z, Glick L, Hall E, Khera R, Kokkinidis D, Kwan J, O'Marr J, Schussheim A, Tuohy E, Wang Y, Spatz E, Jacoby D, Miller E. Short-Term Outcomes After Myopericarditis Related to COVID-19 Vaccination JACC Cardiovascular Imaging 2022, 15: 2002-2005. PMID: 36357140, PMCID: PMC9094612, DOI: 10.1016/j.jcmg.2022.03.026.
Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young AdultsLu Y, Li SX, Liu Y, Rodriguez F, Watson KE, Dreyer RP, Khera R, Murugiah K, D’Onofrio G, Spatz ES, Nasir K, Masoudi FA, Krumholz HM. Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults JAMA Network Open 2022, 5: e229953. PMID: 35503221, PMCID: PMC9066284, DOI: 10.1001/jamanetworkopen.2022.9953.
Abstract 43: A Case-based Survey Of Physician Practice Patterns Following Asymptomatic, Wearable Device-detected Irregular RhythmDemkowicz P, Dhruva S, Spatz E, Beatty A, Ross J, Khera R. Abstract 43: A Case-based Survey Of Physician Practice Patterns Following Asymptomatic, Wearable Device-detected Irregular Rhythm Circulation Cardiovascular Quality And Outcomes 2022, 15 DOI: 10.1161/circoutcomes.15.suppl_1.43.
Abstract 242: Assessing Variation In Data Captured By Clinical Registries And The Electronic Health Record: Clinical Phenotypes Of Patients Undergoing Cardiac CatheterizationSheppard J, Huang C, Mortazavi B, Schulz W, Krumholz H, Khera R. Abstract 242: Assessing Variation In Data Captured By Clinical Registries And The Electronic Health Record: Clinical Phenotypes Of Patients Undergoing Cardiac Catheterization Circulation Cardiovascular Quality And Outcomes 2022, 15 DOI: 10.1161/circoutcomes.15.suppl_1.242.
PO-669-03 MACHINE LEARNING BASED ONE-YEAR MORTALITY PREDICTION IN PATIENTS UNDERGOING PRIMARY PREVENTION CARDIOVERTER DEFIBRILLATOR IMPLANTATION: A RETROSPECTIVE COHORT STUDYZiki M, Annapureddy A, Hurley N, Mahajan S, Murugiah K, Huang C, Caraballo C, Khera R, Ranasinghe I, Curtis J, Rumsfeld J, Masoudi F, Mortazavi B, Krumholz H. PO-669-03 MACHINE LEARNING BASED ONE-YEAR MORTALITY PREDICTION IN PATIENTS UNDERGOING PRIMARY PREVENTION CARDIOVERTER DEFIBRILLATOR IMPLANTATION: A RETROSPECTIVE COHORT STUDY Heart Rhythm 2022, 19: s316-s317. DOI: 10.1016/j.hrthm.2022.03.398.
Abstract 251: Natural Language Processing Of Clinical Documentation To Assess Racial Differences In The Clinical Profile Of Patients Hospitalized With Heart FailureAdejumo P, Rosand B, Khera R. Abstract 251: Natural Language Processing Of Clinical Documentation To Assess Racial Differences In The Clinical Profile Of Patients Hospitalized With Heart Failure Circulation Cardiovascular Quality And Outcomes 2022, 15 DOI: 10.1161/circoutcomes.15.suppl_1.251.
Association Between Center Level Characteristics And 1-Month Post-LVAD Implant Risk Standardized Mortality RatesHendren N, Peltz M, Khera R, Koch S, Young J, Starling R, Tang W, Pandey A, Drazner M, Grodin J. Association Between Center Level Characteristics And 1-Month Post-LVAD Implant Risk Standardized Mortality Rates Journal Of Cardiac Failure 2022, 28: s59. DOI: 10.1016/j.cardfail.2022.03.151.
Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience)Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience) The American Journal Of Cardiology 2022, 173: 33-38. PMID: 35365290, PMCID: PMC9133198, DOI: 10.1016/j.amjcard.2022.03.005.
Automated multilabel diagnosis on electrocardiographic images and signalsSangha V, Mortazavi BJ, Haimovich AD, Ribeiro AH, Brandt CA, Jacoby DL, Schulz WL, Krumholz HM, Ribeiro ALP, Khera R. Automated multilabel diagnosis on electrocardiographic images and signals Nature Communications 2022, 13: 1583. PMID: 35332137, PMCID: PMC8948243, DOI: 10.1038/s41467-022-29153-3.
Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experienceMurugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience PLOS ONE 2022, 17: e0265624. PMID: 35320296, PMCID: PMC8942215, DOI: 10.1371/journal.pone.0265624.
A multicenter evaluation of computable phenotyping approaches for SARS-CoV-2 infection and COVID-19 hospitalizationsKhera R, Mortazavi BJ, Sangha V, Warner F, Patrick Young H, Ross JS, Shah ND, Theel ES, Jenkinson WG, Knepper C, Wang K, Peaper D, Martinello RA, Brandt CA, Lin Z, Ko AI, Krumholz HM, Pollock BD, Schulz WL. A multicenter evaluation of computable phenotyping approaches for SARS-CoV-2 infection and COVID-19 hospitalizations Npj Digital Medicine 2022, 5: 27. PMID: 35260762, PMCID: PMC8904579, DOI: 10.1038/s41746-022-00570-4.
COMPREHENSIVE COMPARATIVE EFFECTIVENESS AND SAFETY OF FIRST-LINE ANTIHYPERTENSIVE MONOTHERAPY IN HYPERTENSIVE PATIENTS: A LARGE-SCALE MULTINATIONAL PARTICIPANT-LEVEL ASSESSMENTLu Y, Khera R, Liu Y, Chen R, Schuemie M, Hripcsak G, Suchard M, Krumholz H. COMPREHENSIVE COMPARATIVE EFFECTIVENESS AND SAFETY OF FIRST-LINE ANTIHYPERTENSIVE MONOTHERAPY IN HYPERTENSIVE PATIENTS: A LARGE-SCALE MULTINATIONAL PARTICIPANT-LEVEL ASSESSMENT Journal Of The American College Of Cardiology 2022, 79: 1577. DOI: 10.1016/s0735-1097(22)02568-2.
COMPREHENSIVE COMPARATIVE EFFECTIVENESS AND SAFETY OF FIRST-LINE CALCIUM CHANNEL BLOCKER MONOTHERAPY IN HYPERTENSIVE PATIENTS: A LARGE-SCALE MULTINATIONAL PARTICIPANT-LEVEL ASSESSMENTLu Y, Khera R, Liu Y, Chen R, Schuemie M, Hripcsak G, Suchard M, Krumholz H. COMPREHENSIVE COMPARATIVE EFFECTIVENESS AND SAFETY OF FIRST-LINE CALCIUM CHANNEL BLOCKER MONOTHERAPY IN HYPERTENSIVE PATIENTS: A LARGE-SCALE MULTINATIONAL PARTICIPANT-LEVEL ASSESSMENT Journal Of The American College Of Cardiology 2022, 79: 1583. DOI: 10.1016/s0735-1097(22)02574-8.
U.S. PATTERNS OF DRUG UTILIZATION AND PRESCRIPTION FILLS FOR PROVEN CARDIOPROTECTIVE ANTI-HYPERGLYCEMIC AGENTSNargesi A, Clark C, Liu M, Chen L, Reddy A, Amodeo S, Oikonomou E, Suchard M, Lipska K, McGuire D, Lin Z, Inzucchi S, Krumholz H, Khera R. U.S. PATTERNS OF DRUG UTILIZATION AND PRESCRIPTION FILLS FOR PROVEN CARDIOPROTECTIVE ANTI-HYPERGLYCEMIC AGENTS Journal Of The American College Of Cardiology 2022, 79: 1446. DOI: 10.1016/s0735-1097(22)02437-8.
ALL-CAUSE MORTALITY AND FINANCIAL TOXICITY AMONG US ADULTS WITH ASCVDElizondo J, Khera R, Ali H, Wang S, Javed Z, Hagan K, Mossialos E, Cainzos-Achirica M, Nasir K. ALL-CAUSE MORTALITY AND FINANCIAL TOXICITY AMONG US ADULTS WITH ASCVD Journal Of The American College Of Cardiology 2022, 79: 1465. DOI: 10.1016/s0735-1097(22)02456-1.
IDENTIFICATION OF HEART FAILURE WITH REDUCED EJECTION FRACTION FROM HOSPITALIZATION DISCHARGE SUMMARIES USING NATURAL LANGUAGE PROCESSINGHengartner A, Rosand B, Adejumo P, Chen L, Nargesi A, Khera R. IDENTIFICATION OF HEART FAILURE WITH REDUCED EJECTION FRACTION FROM HOSPITALIZATION DISCHARGE SUMMARIES USING NATURAL LANGUAGE PROCESSING Journal Of The American College Of Cardiology 2022, 79: 357. DOI: 10.1016/s0735-1097(22)01348-1.
PERSONALIZING THE THERAPEUTIC BENEFIT FROM SPIRONOLACTONE IN HEART FAILURE WITH PRESERVED EJECTION FRACTION THROUGH COMPUTATIONAL PHENOMAPS OF THE TOPCAT TRIAL AND MACHINE LEARNINGOikonomou E, Suchard M, Khera R. PERSONALIZING THE THERAPEUTIC BENEFIT FROM SPIRONOLACTONE IN HEART FAILURE WITH PRESERVED EJECTION FRACTION THROUGH COMPUTATIONAL PHENOMAPS OF THE TOPCAT TRIAL AND MACHINE LEARNING Journal Of The American College Of Cardiology 2022, 79: 424. DOI: 10.1016/s0735-1097(22)01415-2.
NATIONAL PATTERNS OF ELIGIBILITY FOR AND UTILIZATION OF FDA-APPROVED WEIGHT-LOSS AGENTS AMONG US ADULTS, 2015-2018Demkowicz P, Nargesi A, Khera R. NATIONAL PATTERNS OF ELIGIBILITY FOR AND UTILIZATION OF FDA-APPROVED WEIGHT-LOSS AGENTS AMONG US ADULTS, 2015-2018 Journal Of The American College Of Cardiology 2022, 79: 1444. DOI: 10.1016/s0735-1097(22)02435-4.
NATIONAL PATTERNS OF ELIGIBILITY AND USE OF NOVEL LIPID LOWERING THERAPIES IN THE UNITED STATESShen M, Nargesi A, Nasir K, Khera R. NATIONAL PATTERNS OF ELIGIBILITY AND USE OF NOVEL LIPID LOWERING THERAPIES IN THE UNITED STATES Journal Of The American College Of Cardiology 2022, 79: 1563. DOI: 10.1016/s0735-1097(22)02554-2.
CHARACTERISTICS OF HIGH-PERFORMING HOSPITALS FOR CARDIOGENIC SHOCK FOLLOWING ACUTE MYOCARDIAL INFARCTIONKumbhani D, Li S, de Lemos J, Pandey A, Bhatt D, Fonarow G, Nallamothu B, Wang T, Matsouaka R, Bavry A, Das S, Grodin J, Khera R, Drazner M. CHARACTERISTICS OF HIGH-PERFORMING HOSPITALS FOR CARDIOGENIC SHOCK FOLLOWING ACUTE MYOCARDIAL INFARCTION Journal Of The American College Of Cardiology 2022, 79: 976. DOI: 10.1016/s0735-1097(22)01967-2.
Phenomapping-Derived Tool to Individualize the Effect of Canagliflozin on Cardiovascular Risk in Type 2 Diabetes.Oikonomou EK, Suchard MA, McGuire DK, Khera R. Phenomapping-Derived Tool to Individualize the Effect of Canagliflozin on Cardiovascular Risk in Type 2 Diabetes. Diabetes Care 2022, 45: 965-974. PMID: 35120199, PMCID: PMC9016734, DOI: 10.2337/dc21-1765.
Abstract WP215: Population Attributable Risks For Potentially Modifiable Risk Factors Of Cerebrovascular And Cardiovascular-related Mortality In The National Health And Nutrition Examination SurveySharma R, Baker A, Mszar R, Leasure A, Khera R, de Havenon A, Lu Y, Jasne A, Forman R, Sheth K, Krumholz H, Sharma R. Abstract WP215: Population Attributable Risks For Potentially Modifiable Risk Factors Of Cerebrovascular And Cardiovascular-related Mortality In The National Health And Nutrition Examination Survey Stroke 2022, 53: awp215-awp215. DOI: 10.1161/str.53.suppl_1.wp215.
Cost-Related Medication Nonadherence in Adults With Diabetes in the United States: The National Health Interview Survey 2013-2018.Taha MB, Valero-Elizondo J, Yahya T, Caraballo C, Khera R, Patel KV, Ali HJR, Sharma G, Mossialos E, Cainzos-Achirica M, Nasir K. Cost-Related Medication Nonadherence in Adults With Diabetes in the United States: The National Health Interview Survey 2013-2018. Diabetes Care 2022, 45: 594-603. PMID: 35015860, DOI: 10.2337/dc21-1757.
Assessing Performance of Machine Learning—ReplyKhera R, Mortazavi BJ, Krumholz HM. Assessing Performance of Machine Learning—Reply JAMA Cardiology 2021, 6: 1466-1466. PMID: 34586344, DOI: 10.1001/jamacardio.2021.3715.
Clinician Trends in Prescribing Direct Oral Anticoagulants for US Medicare BeneficiariesWheelock KM, Ross JS, Murugiah K, Lin Z, Krumholz HM, Khera R. Clinician Trends in Prescribing Direct Oral Anticoagulants for US Medicare Beneficiaries JAMA Network Open 2021, 4: e2137288. PMID: 34870678, PMCID: PMC8649845, DOI: 10.1001/jamanetworkopen.2021.37288.
Abstract 13686: Variation in Time in Therapeutic Range for Cooling for Out-of-Hospital Cardiac ArrestWheelock K, Chen L, Girotra S, Chan P, Khera R. Abstract 13686: Variation in Time in Therapeutic Range for Cooling for Out-of-Hospital Cardiac Arrest Circulation 2021, 144 DOI: 10.1161/circ.144.suppl_2.13686.
Abstract 13948: Patterns of Prescribing Sodium-Glucose Cotransporter-2 Inhibitors for Medicare Beneficiaries in the United StatesSangha V, Lipska K, Lin Z, Inzucchi S, McGuire D, Krumholz H, Khera R. Abstract 13948: Patterns of Prescribing Sodium-Glucose Cotransporter-2 Inhibitors for Medicare Beneficiaries in the United States Circulation 2021, 144: a13948-a13948. DOI: 10.1161/circ.144.suppl_1.13948.
Abstract 13668: Out-of-Pocket Health Spending and Subjective Financial Hardship in Atherosclerotic Cardiovascular Disease and Heart Failure in the United StatesWang S, Elizondo J, Nasir K, Khera R. Abstract 13668: Out-of-Pocket Health Spending and Subjective Financial Hardship in Atherosclerotic Cardiovascular Disease and Heart Failure in the United States Circulation 2021, 144: a13668-a13668. DOI: 10.1161/circ.144.suppl_1.13668.
Abstract 12604: Prescribing Patterns of Cardioprotective Antihyperglycemics Among Medicare Beneficiaries Across United States Counties by their Socioeconomic DisadvantageousnessHanna J, Aghajaninargesi A, Sangha V, Lin Z, Krumholz H, Khera R. Abstract 12604: Prescribing Patterns of Cardioprotective Antihyperglycemics Among Medicare Beneficiaries Across United States Counties by their Socioeconomic Disadvantageousness Circulation 2021, 144: a12604-a12604. DOI: 10.1161/circ.144.suppl_1.12604.
Abstract 13965: Natural Language Processing of Hospitalization Discharge Summary to Predict 1-year Post-Discharge Mortality Among Patients With Acute Heart FailureRosand B, Radev D, Krumholz H, Khera R. Abstract 13965: Natural Language Processing of Hospitalization Discharge Summary to Predict 1-year Post-Discharge Mortality Among Patients With Acute Heart Failure Circulation 2021, 144: a13965-a13965. DOI: 10.1161/circ.144.suppl_1.13965.
Abstract 13877: Financial Hardship From Medical Bills Among Non-Elderly Adults With Obesity in the USMahajan S, Elizondo J, Khera R, Taha M, Acquah I, Achirica M, Krumholz H, Nasir K. Abstract 13877: Financial Hardship From Medical Bills Among Non-Elderly Adults With Obesity in the US Circulation 2021, 144: a13877-a13877. DOI: 10.1161/circ.144.suppl_1.13877.
Abstract 11487: Individualizing the Cardiovascular Benefits of Intensive Blood Pressure Reduction Using Computational Phenomaps of the SPRINT and ACCORD TrialsOikonomou E, Suchard M, Khera R. Abstract 11487: Individualizing the Cardiovascular Benefits of Intensive Blood Pressure Reduction Using Computational Phenomaps of the SPRINT and ACCORD Trials Circulation 2021, 144: a11487-a11487. DOI: 10.1161/circ.144.suppl_1.11487.
Abstract 9358: Individualizing Cardiovascular Benefits of Canagliflozin Based on Multidimensional Computational Phenomaps of the CANVAS TrialsOikonomou E, Suchard M, McGuire D, Khera R. Abstract 9358: Individualizing Cardiovascular Benefits of Canagliflozin Based on Multidimensional Computational Phenomaps of the CANVAS Trials Circulation 2021, 144: a9358-a9358. DOI: 10.1161/circ.144.suppl_1.9358.
Abstract 13957: Predicting In-Hospital Mortality Among Patients Hospitalized With Heart Failure Using a Convolutional Neural Network and Transfer Learning on a Single Admission Chest X-RayHidalgo-Goto D, Dhingra L, Sangha V, Oikonomou E, Khera R. Abstract 13957: Predicting In-Hospital Mortality Among Patients Hospitalized With Heart Failure Using a Convolutional Neural Network and Transfer Learning on a Single Admission Chest X-Ray Circulation 2021, 144: a13957-a13957. DOI: 10.1161/circ.144.suppl_1.13957.
Abstract 13912: ECG-DualNet: A MultiLabel Model for Automated Diagnosis on Both Electrocardiographic Signals and Printed 12-lead ElectrocardiogramsSangha V, Khera R. Abstract 13912: ECG-DualNet: A MultiLabel Model for Automated Diagnosis on Both Electrocardiographic Signals and Printed 12-lead Electrocardiograms Circulation 2021, 144: a13912-a13912. DOI: 10.1161/circ.144.suppl_1.13912.
Abstract 11532: Variation in Coronary Angiography Use in Out-of-Hospital Cardiac ArrestDale P, Khera R, Siobhan B, Idris A, Link M, Mody P. Abstract 11532: Variation in Coronary Angiography Use in Out-of-Hospital Cardiac Arrest Circulation 2021, 144 DOI: 10.1161/circ.144.suppl_2.11532.
Abstract 11520: Cost-Related Medication Nonadherence in Adults with Diabetes Mellitus in the United StatesTaha M, Elizondo J, Caraballo C, Yahya T, Khera R, Satish P, Acquah I, Hagan K, Patel K, Mossialos E, Achirica M, Nasir K. Abstract 11520: Cost-Related Medication Nonadherence in Adults with Diabetes Mellitus in the United States Circulation 2021, 144: a11520-a11520. DOI: 10.1161/circ.144.suppl_1.11520.
Abstract 11909: Racial and Gender Differences in Lifetime Healthcare Costs Across Cardiovascular Risk FactorsKhera R, Liu M, Kondamudi N, Spatz E, Ayers C, Powell-wiley T, Halm E, Pandey A. Abstract 11909: Racial and Gender Differences in Lifetime Healthcare Costs Across Cardiovascular Risk Factors Circulation 2021, 144: a11909-a11909. DOI: 10.1161/circ.144.suppl_1.11909.
Abstract 14027: National Trends and County-Level Patterns of Prescription for PCSK-9 Inhibitors Among Medicare Beneficiaries in the United StatesNargesi A, Hanna J, Khera R. Abstract 14027: National Trends and County-Level Patterns of Prescription for PCSK-9 Inhibitors Among Medicare Beneficiaries in the United States Circulation 2021, 144: a14027-a14027. DOI: 10.1161/circ.144.suppl_1.14027.
Patterns of Prescribing Sodium-Glucose Cotransporter-2 Inhibitors for Medicare Beneficiaries in the United StatesSangha V, Lipska K, Lin Z, Inzucchi SE, McGuire DK, Krumholz HM, Khera R. Patterns of Prescribing Sodium-Glucose Cotransporter-2 Inhibitors for Medicare Beneficiaries in the United States Circulation Cardiovascular Quality And Outcomes 2021, 14: e008381. PMID: 34779654, PMCID: PMC9022137, DOI: 10.1161/circoutcomes.121.008381.
Nonalcoholic Fatty Liver Disease and Risk of Heart Failure Among Medicare BeneficiariesFudim M, Zhong L, Patel KV, Khera R, Abdelmalek MF, Diehl AM, McGarrah RW, Molinger J, Moylan CA, Rao VN, Wegermann K, Neeland IJ, Halm EA, Das SR, Pandey A. Nonalcoholic Fatty Liver Disease and Risk of Heart Failure Among Medicare Beneficiaries Journal Of The American Heart Association 2021, 10: e021654. PMID: 34755544, PMCID: PMC8751938, DOI: 10.1161/jaha.121.021654.
Digital Cardiovascular Epidemiology—Ushering in a New Era Through Computational Phenotyping of Cardiovascular DiseaseKhera R. Digital Cardiovascular Epidemiology—Ushering in a New Era Through Computational Phenotyping of Cardiovascular Disease JAMA Network Open 2021, 4: e2135561. PMID: 34807263, DOI: 10.1001/jamanetworkopen.2021.35561.
Comparison of Machine Learning Approaches for Missing Data Imputation Among Non-Small Cell Lung Cancer PatientsYang D, Khera R, Chang E, Joel M, Janda G, Park H, Aneja S. Comparison of Machine Learning Approaches for Missing Data Imputation Among Non-Small Cell Lung Cancer Patients International Journal Of Radiation Oncology • Biology • Physics 2021, 111: s115. DOI: 10.1016/j.ijrobp.2021.07.264.
TCT-100 Real-World Experience and Outcomes of Protected Versus Unprotected Left Main Percutaneous Coronary Intervention: Insights From the VA CART ProgramHussain Y, Gonzalez P, Khera R, Banerjee S, Hebbe A, Plomondon M, Waldo S, Pfau S, Curtis J, Shah S. TCT-100 Real-World Experience and Outcomes of Protected Versus Unprotected Left Main Percutaneous Coronary Intervention: Insights From the VA CART Program Journal Of The American College Of Cardiology 2021, 78: b42. DOI: 10.1016/j.jacc.2021.09.950.
Scope of Practice of US Interventional Cardiologists from an Analysis of Medicare Billing DataMurugiah K, Chen L, Castro-Dominguez Y, Khera R, Krumholz HM. Scope of Practice of US Interventional Cardiologists from an Analysis of Medicare Billing Data The American Journal Of Cardiology 2021, 160: 40-45. PMID: 34610872, DOI: 10.1016/j.amjcard.2021.08.041.
Sentiment analysis of tweets on prior authorization.Prasanna S, Premnath N, Angraal S, Sedhom R, Khera R, Parsons H, Hussaini S, Johnson P, Lou E, Beg M, Subbiah I, Rao P, Gupta A. Sentiment analysis of tweets on prior authorization. Journal Of Clinical Oncology 2021, 39: 322-322. DOI: 10.1200/jco.2020.39.28_suppl.322.
Scope and Social Determinants of Food Insecurity Among Adults With Atherosclerotic Cardiovascular Disease in the United StatesMahajan S, Grandhi GR, Valero‐Elizondo J, Mszar R, Khera R, Acquah I, Yahya T, Virani SS, Blankstein R, Blaha MJ, Cainzos‐Achirica M, Nasir K. Scope and Social Determinants of Food Insecurity Among Adults With Atherosclerotic Cardiovascular Disease in the United States Journal Of The American Heart Association 2021, 10: e020028. PMID: 34387089, PMCID: PMC8475063, DOI: 10.1161/jaha.120.020028.
Forgone Medical Care Associated With Increased Health Care Costs Among the U.S. Heart Failure PopulationThomas A, Valero-Elizondo J, Khera R, Warraich HJ, Reinhardt SW, Ali HJ, Nasir K, Desai NR. Forgone Medical Care Associated With Increased Health Care Costs Among the U.S. Heart Failure Population JACC Heart Failure 2021, 9: 710-719. PMID: 34391737, DOI: 10.1016/j.jchf.2021.05.010.
Comparative Outcomes of Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Among Medicare Beneficiaries With Multivessel Coronary Artery Disease: An National Cardiovascular Data Registry Research to Practice ProjectSecemsky EA, Butala N, Raja A, Khera R, Wang Y, Curtis JP, Maddox TM, Virani SS, Armstrong EJ, Shunk KA, Brindis RG, Bhatt D, Yeh RW. Comparative Outcomes of Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Among Medicare Beneficiaries With Multivessel Coronary Artery Disease: An National Cardiovascular Data Registry Research to Practice Project Circulation Cardiovascular Interventions 2021, 14: e010323. PMID: 34372676, PMCID: PMC8485756, DOI: 10.1161/circinterventions.120.010323.
Association of COVID-19 Hospitalization Volume and Case Growth at US Hospitals with Patient OutcomesKhera R, Liu Y, de Lemos JA, Das SR, Pandey A, Omar W, Kumbhani DJ, Girotra S, Yeh RW, Rutan C, Walchok J, Lin Z, Bradley SM, Velazquez EJ, Churchwell KB, Nallamothu BK, Krumholz HM, Curtis JP. Association of COVID-19 Hospitalization Volume and Case Growth at US Hospitals with Patient Outcomes The American Journal Of Medicine 2021, 134: 1380-1388.e3. PMID: 34343515, PMCID: PMC8325555, DOI: 10.1016/j.amjmed.2021.06.034.
Sparse Gated Mixture-of-Experts to Separate and Interpret Patient Heterogeneity in EHR dataHuo Z, Zhang L, Khera R, Huang S, Qian X, Wang Z, Mortazavi B. Sparse Gated Mixture-of-Experts to Separate and Interpret Patient Heterogeneity in EHR data 2021, 00: 1-4. DOI: 10.1109/bhi50953.2021.9508549.
Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD RegistryBradley SM, Emmons-Bell S, Mutharasan RK, Rodriguez F, Gupta D, Roth G, Gluckman TJ, Shah RU, Wang TY, Khera R, Peterson PN, Das S. Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD Registry Scientific Reports 2021, 11: 15097. PMID: 34302004, PMCID: PMC8302649, DOI: 10.1038/s41598-021-94203-7.
Financial Hardship Among Nonelderly Adults With CKD in the United StatesAcquah I, Valero-Elizondo J, Javed Z, Ibrahim HN, Patel KV, Ryoo Ali HJ, Menser T, Khera R, Cainzos-Achirica M, Nasir K. Financial Hardship Among Nonelderly Adults With CKD in the United States American Journal Of Kidney Diseases 2021, 78: 658-668. PMID: 34144103, DOI: 10.1053/j.ajkd.2021.04.011.
Atherosclerotic Cardiovascular Disease, Cancer, and Financial Toxicity Among Adults in the United StatesValero-Elizondo J, Chouairi F, Khera R, Grandhi GR, Saxena A, Warraich HJ, Virani SS, Desai NR, Sasangohar F, Krumholz HM, Esnaola NF, Nasir K. Atherosclerotic Cardiovascular Disease, Cancer, and Financial Toxicity Among Adults in the United States JACC CardioOncology 2021, 3: 236-246. PMID: 34396329, PMCID: PMC8352280, DOI: 10.1016/j.jaccao.2021.02.006.
Cost-Related Nonadherence to Medications Among US Adults With Chronic Liver DiseasesLago-Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. Cost-Related Nonadherence to Medications Among US Adults With Chronic Liver Diseases Mayo Clinic Proceedings 2021, 96: 2639-2650. PMID: 34120754, PMCID: PMC8492496, DOI: 10.1016/j.mayocp.2021.02.026.
Association of Kidney Disease With Outcomes in COVID‐19: Results From the American Heart Association COVID‐19 Cardiovascular Disease RegistryRao A, Ranka S, Ayers C, Hendren N, Rosenblatt A, Alger HM, Rutan C, Omar W, Khera R, Gupta K, Mody P, DeFilippi C, Das SR, Hedayati SS, de Lemos JA. Association of Kidney Disease With Outcomes in COVID‐19: Results From the American Heart Association COVID‐19 Cardiovascular Disease Registry Journal Of The American Heart Association 2021, 10: e020910. PMID: 34107743, PMCID: PMC8477855, DOI: 10.1161/jaha.121.020910.
Financial Hardship From Medical Bills Among Adults With Chronic Liver Diseases: National Estimates From the United StatesLago‐Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. Financial Hardship From Medical Bills Among Adults With Chronic Liver Diseases: National Estimates From the United States Hepatology 2021, 74: 1509-1522. PMID: 33772833, DOI: 10.1002/hep.31835.
Use of Machine Learning Models to Predict Death After Acute Myocardial InfarctionKhera R, Haimovich J, Hurley NC, McNamara R, Spertus JA, Desai N, Rumsfeld JS, Masoudi FA, Huang C, Normand SL, Mortazavi BJ, Krumholz HM. Use of Machine Learning Models to Predict Death After Acute Myocardial Infarction JAMA Cardiology 2021, 6: 633-641. PMID: 33688915, PMCID: PMC7948114, DOI: 10.1001/jamacardio.2021.0122.
Out‐of‐pocket Annual Health Expenditures and Financial Toxicity from Healthcare Costs in Patients with Heart Failure in the United StatesWang SY, Valero‐Elizondo J, Ali H, Pandey A, Cainzos‐Achirica M, Krumholz HM, Nasir K, Khera R. Out‐of‐pocket Annual Health Expenditures and Financial Toxicity from Healthcare Costs in Patients with Heart Failure in the United States Journal Of The American Heart Association 2021, 10: e022164. PMID: 33998273, PMCID: PMC8483501, DOI: 10.1161/jaha.121.022164.
Contemporary National Patterns of Eligibility and Utilization of Novel Cardioprotective Anti‐hyperglycemic agents in Type 2 DiabetesNargesi AA, Jeyashanmugaraja GP, Desai N, Lipska K, Krumholz H, Khera R. Contemporary National Patterns of Eligibility and Utilization of Novel Cardioprotective Anti‐hyperglycemic agents in Type 2 Diabetes Journal Of The American Heart Association 2021, 10: e021084. PMID: 33998258, PMCID: PMC8403287, DOI: 10.1161/jaha.121.021084.
Accuracy of Computable Phenotyping Approaches for SARS-CoV-2 Infection and COVID-19 Hospitalizations from the Electronic Health Record.Khera R, Mortazavi BJ, Sangha V, Warner F, Young HP, Ross JS, Shah ND, Theel ES, Jenkinson WG, Knepper C, Wang K, Peaper D, Martinello RA, Brandt CA, Lin Z, Ko AI, Krumholz HM, Pollock BD, Schulz WL. Accuracy of Computable Phenotyping Approaches for SARS-CoV-2 Infection and COVID-19 Hospitalizations from the Electronic Health Record. MedRxiv : The Preprint Server For Health Sciences 2021 PMID: 34013299, PMCID: PMC8132274, DOI: 10.1101/2021.03.16.21253770.
Projected 30- day out-of-pocket costs and total spending on pancreatic enzyme replacement therapy under Medicare Part DGupta A, Premnath N, Sedhom R, Beg MS, Khera R, Laheru DA, Dusetzina SB. Projected 30- day out-of-pocket costs and total spending on pancreatic enzyme replacement therapy under Medicare Part D Pancreatology 2021, 21: 1009-1010. PMID: 34006458, DOI: 10.1016/j.pan.2021.05.002.
Financial burden, distress, and toxicity in cardiovascular diseaseSlavin SD, Khera R, Zafar SY, Nasir K, Warraich HJ. Financial burden, distress, and toxicity in cardiovascular disease American Heart Journal 2021, 238: 75-84. PMID: 33961830, DOI: 10.1016/j.ahj.2021.04.011.
Temporal Changes and Institutional Variation in Use of Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction With Multivessel Coronary Artery Disease in the United StatesSecemsky EA, Butala N, Raja A, Khera R, Wang Y, Curtis JP, Maddox TM, Virani SS, Armstrong EJ, Shunk KA, Brindis RG, Bhatt D, Yeh RW. Temporal Changes and Institutional Variation in Use of Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction With Multivessel Coronary Artery Disease in the United States JAMA Cardiology 2021, 6: 574-580. PMID: 33146666, PMCID: PMC7643043, DOI: 10.1001/jamacardio.2020.5354.
NATIONAL PATTERNS OF DIRECT ORAL ANTICOAGULANT PRESCRIBING BY UNITED STATES CLINICIANS AMONG MEDICARE BENEFICIARIESWheelock K, Ross J, Murugiah K, Lin Z, Krumholz H, Khera R. NATIONAL PATTERNS OF DIRECT ORAL ANTICOAGULANT PRESCRIBING BY UNITED STATES CLINICIANS AMONG MEDICARE BENEFICIARIES Journal Of The American College Of Cardiology 2021, 77: 336. DOI: 10.1016/s0735-1097(21)01695-8.
CASEATING CALCIFICATION OF MITRAL ANNULUS MASQUERADING AS CARDIAC TUMORAnnapureddy A, Bonde P, Khera R. CASEATING CALCIFICATION OF MITRAL ANNULUS MASQUERADING AS CARDIAC TUMOR Journal Of The American College Of Cardiology 2021, 77: 2618. DOI: 10.1016/s0735-1097(21)03973-5.
CONTEMPORARY NATIONAL PATTERNS OF ELIGIBILITY AND UTILIZATION OF NOVEL CARDIOPROTECTIVE ANTI-HYPERGLYCEMIC AGENTS IN TYPE 2 DIABETESNargesi A, Jeyashanmugaraja G, Desai N, Lipska K, Krumholz H, Khera R. CONTEMPORARY NATIONAL PATTERNS OF ELIGIBILITY AND UTILIZATION OF NOVEL CARDIOPROTECTIVE ANTI-HYPERGLYCEMIC AGENTS IN TYPE 2 DIABETES Journal Of The American College Of Cardiology 2021, 77: 1535. DOI: 10.1016/s0735-1097(21)02893-x.
ASSOCIATION OF OUT-OF-POCKET ANNUAL HEALTH EXPENDITURES WITH FINANCIAL HARDSHIP IN ADULTS WITH HEART FAILURE IN THE UNITED STATESWang S, Elizondo J, Ali H, Cainzos-Achirica M, Pandey A, Nasir K, Khera R. ASSOCIATION OF OUT-OF-POCKET ANNUAL HEALTH EXPENDITURES WITH FINANCIAL HARDSHIP IN ADULTS WITH HEART FAILURE IN THE UNITED STATES Journal Of The American College Of Cardiology 2021, 77: 789. DOI: 10.1016/s0735-1097(21)02148-3.
FINANCIAL HARDSHIP FROM MEDICAL BILLS AMONG PATIENTS WITH HEART FAILURE IN THE UNITED STATESAli H, Elizondo J, Wang S, Bhimaraj A, Khan S, Khan M, Cainzos-Achirica M, Khera R, Nasir K. FINANCIAL HARDSHIP FROM MEDICAL BILLS AMONG PATIENTS WITH HEART FAILURE IN THE UNITED STATES Journal Of The American College Of Cardiology 2021, 77: 785. DOI: 10.1016/s0735-1097(21)02144-6.
COMPARATIVE CARDIOVASCULAR EFFECTIVENESS AND SAFETY OF INDIVIDUAL ANGIOTENSIN-CONVERTING ENZYME INHIBITORS AND ANGIOTENSIN RECEPTOR BLOCKERS: A MULTINATIONAL PARTICIPANT-LEVEL ASSESSMENT FROM LEGEND-HTNKhera R, Lu Y, Chen R, Schuemie M, Hripcsak G, Krumholz H, Suchard M. COMPARATIVE CARDIOVASCULAR EFFECTIVENESS AND SAFETY OF INDIVIDUAL ANGIOTENSIN-CONVERTING ENZYME INHIBITORS AND ANGIOTENSIN RECEPTOR BLOCKERS: A MULTINATIONAL PARTICIPANT-LEVEL ASSESSMENT FROM LEGEND-HTN Journal Of The American College Of Cardiology 2021, 77: 1474. DOI: 10.1016/s0735-1097(21)02832-1.
A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST).Oikonomou EK, Van Dijk D, Parise H, Suchard MA, de Lemos J, Antoniades C, Velazquez EJ, Miller EJ, Khera R. A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST). European Heart Journal 2021, 42: 2536-2548. PMID: 33881513, PMCID: PMC8488385, DOI: 10.1093/eurheartj/ehab223.
Electronic Health Record Risk Score Provides Earlier Prognostication of Clinical Outcomes in Patients Admitted to the Cardiac Intensive Care UnitKunitomo Y, Thomas A, Chouairi F, Canavan ME, Kochar A, Khera R, Katz JN, Murphy C, Jentzer J, Ahmad T, Desai NR, Brennan J, Miller PE. Electronic Health Record Risk Score Provides Earlier Prognostication of Clinical Outcomes in Patients Admitted to the Cardiac Intensive Care Unit American Heart Journal 2021, 238: 85-88. PMID: 33891906, DOI: 10.1016/j.ahj.2021.04.004.
Performance of the Pooled Cohort Equations in Hispanic Individuals Across the United States: Insights From the Multi‐Ethnic Study of Atherosclerosis and the Dallas Heart StudyRosario K, Mehta A, Ayers C, Gonzalez P, Pandey A, Khera R, Kaplan R, Blaha MJ, Khera A, Blumenthal RS, Nasir K, Rodriguez CJ, Joshi PH. Performance of the Pooled Cohort Equations in Hispanic Individuals Across the United States: Insights From the Multi‐Ethnic Study of Atherosclerosis and the Dallas Heart Study Journal Of The American Heart Association 2021, 10: e018410. PMID: 33870702, PMCID: PMC8200750, DOI: 10.1161/jaha.120.018410.
Prevalence of Missing Data in the National Cancer Database and Association With Overall SurvivalYang DX, Khera R, Miccio JA, Jairam V, Chang E, Yu JB, Park HS, Krumholz HM, Aneja S. Prevalence of Missing Data in the National Cancer Database and Association With Overall Survival JAMA Network Open 2021, 4: e211793. PMID: 33755165, PMCID: PMC7988369, DOI: 10.1001/jamanetworkopen.2021.1793.
Association of Angiotensin‐Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease‐19Khera R, Clark C, Lu Y, Guo Y, Ren S, Truax B, Spatz ES, Murugiah K, Lin Z, Omer SB, Vojta D, Krumholz HM. Association of Angiotensin‐Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease‐19 Journal Of The American Heart Association 2021, 10: e018086. PMID: 33624516, PMCID: PMC8403305, DOI: 10.1161/jaha.120.018086.
Projected 30-day out-of-pocket and total spending on pancreatic enzyme replacement therapy under Medicare Part D.Gupta A, Premnath N, Beg M, Khera R, Dusetzina S. Projected 30-day out-of-pocket and total spending on pancreatic enzyme replacement therapy under Medicare Part D. Journal Of Clinical Oncology 2021, 39: 401-401. DOI: 10.1200/jco.2021.39.3_suppl.401.
Evaluation of Internet-Based Crowdsourced Fundraising to Cover Health Care Costs in the United StatesAngraal S, Zachariah AG, Raaisa R, Khera R, Rao P, Krumholz HM, Spertus JA. Evaluation of Internet-Based Crowdsourced Fundraising to Cover Health Care Costs in the United States JAMA Network Open 2021, 4: e2033157. PMID: 33427882, PMCID: PMC7801937, DOI: 10.1001/jamanetworkopen.2020.33157.
Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19Hendren NS, de Lemos JA, Ayers C, Das SR, Rao A, Carter S, Rosenblatt A, Walchok J, Omar W, Khera R, Hegde AA, Drazner MH, Neeland IJ, Grodin JL. Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19 Circulation 2020, 143: 135-144. PMID: 33200947, DOI: 10.1161/circulationaha.120.051936.
Abstract 15779: Unfavorable Social Determinants of Health Profile and Financial Toxicity From Healthcare in Atherosclerotic Cardiovascular DiseaseValero Elizondo J, Khera R, Dudum R, Acquah I, Hyder A, Andrieni J, Sharma G, Blaha M, Virani S, Blankstein R, Cainzos Achirica M, Nasir K. Abstract 15779: Unfavorable Social Determinants of Health Profile and Financial Toxicity From Healthcare in Atherosclerotic Cardiovascular Disease Circulation 2020, 142 DOI: 10.1161/circ.142.suppl_3.15779.
Pumping the Breaks on Health Care Costs of Cardiac Surgery by Focusing on Postacute Care SpendingMori M, Khera R. Pumping the Breaks on Health Care Costs of Cardiac Surgery by Focusing on Postacute Care Spending Circulation Cardiovascular Quality And Outcomes 2020, 13: e007253. PMID: 33176464, DOI: 10.1161/circoutcomes.120.007253.
Association Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young AdultsMszar R, Mahajan S, Valero-Elizondo J, Yahya T, Sharma R, Grandhi GR, Khera R, Virani SS, Lichtman J, Khan SU, Cainzos-Achirica M, Vahidy FS, Krumholz HM, Nasir K. Association Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young Adults Stroke 2020, 51: 3552-3561. PMID: 33100188, DOI: 10.1161/strokeaha.120.031137.
National Estimates of Financial Hardship From Medical Bills and Cost-related Medication Nonadherence in Patients With Inflammatory Bowel Diseases in the United States.Nguyen NH, Khera R, Dulai PS, Boland BS, Ohno-Machado L, Sandborn WJ, Singh S. National Estimates of Financial Hardship From Medical Bills and Cost-related Medication Nonadherence in Patients With Inflammatory Bowel Diseases in the United States. Inflammatory Bowel Diseases 2020, 27: 1068-1078. PMID: 33051681, PMCID: PMC8205631, DOI: 10.1093/ibd/izaa266.
Trends in Reoperative Coronary Artery Bypass Graft Surgery for Older Adults in the United States, 1998 to 2017Mori M, Wang Y, Murugiah K, Khera R, Gupta A, Vallabhajosyula P, Masoudi FA, Geirsson A, Krumholz HM. Trends in Reoperative Coronary Artery Bypass Graft Surgery for Older Adults in the United States, 1998 to 2017 Journal Of The American Heart Association 2020, 9: e016980. PMID: 33045889, PMCID: PMC7763387, DOI: 10.1161/jaha.120.016980.
Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018Khera R, Secemsky EA, Wang Y, Desai NR, Krumholz HM, Maddox TM, Shunk KA, Virani SS, Bhatt DL, Curtis J, Yeh RW. Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018 JAMA Internal Medicine 2020, 180: 1317-1327. PMID: 32833024, PMCID: PMC9377424, DOI: 10.1001/jamainternmed.2020.3276.
Temporal Trends in Heart Failure Incidence Among Medicare Beneficiaries Across Risk Factor Strata, 2011 to 2016Khera R, Kondamudi N, Zhong L, Vaduganathan M, Parker J, Das SR, Grodin JL, Halm EA, Berry JD, Pandey A. Temporal Trends in Heart Failure Incidence Among Medicare Beneficiaries Across Risk Factor Strata, 2011 to 2016 JAMA Network Open 2020, 3: e2022190. PMID: 33095250, PMCID: PMC7584929, DOI: 10.1001/jamanetworkopen.2020.22190.
Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass IndexKhera R, Pandey A, Ayers CR, Carnethon MR, Greenland P, Ndumele CE, Nambi V, Seliger SL, Chaves PHM, Safford MM, Cushman M, Xanthakis V, Ramachandran V, Mentz RJ, Correa A, Lloyd-Jones DM, Berry JD, de Lemos JA, Neeland IJ. Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass Index JAMA Network Open 2020, 3: e2023242. PMID: 33119108, PMCID: PMC7596579, DOI: 10.1001/jamanetworkopen.2020.23242.
PREDICTING RISK OF 30-DAY ALL-CAUSE READMISSION FOLLOWING HOSPITALIZATION FOR COPD USING EHR DATAJain S, Khera R, Clark C, DeLisle S, Halm E. PREDICTING RISK OF 30-DAY ALL-CAUSE READMISSION FOLLOWING HOSPITALIZATION FOR COPD USING EHR DATA CHEST Journal 2020, 158: a1764. DOI: 10.1016/j.chest.2020.08.1542.
The Upcoming Epidemic of Heart Failure in South AsiaMartinez-Amezcua P, Haque W, Khera R, Kanaya AM, Sattar N, Lam CSP, Harikrishnan S, Shah SJ, Kandula NR, Jose PO, Narayan KMV, Agyemang C, Misra A, Jenum AK, Bilal U, Nasir K, Cainzos-Achirica M. The Upcoming Epidemic of Heart Failure in South Asia Circulation Heart Failure 2020, 13: e007218. PMID: 32962410, DOI: 10.1161/circheartfailure.120.007218.
Financial Toxicity in Atherosclerotic Cardiovascular Disease in the United States: Current State and Future DirectionsKhera R, Valero-Elizondo J, Nasir K. Financial Toxicity in Atherosclerotic Cardiovascular Disease in the United States: Current State and Future Directions Journal Of The American Heart Association 2020, 9: e017793. PMID: 32924728, PMCID: PMC7792407, DOI: 10.1161/jaha.120.017793.
Characteristics of cardiac catheterization laboratory directors at the 2017 U.S. News & World Report top 100 U.S. cardiovascular hospitalsMurugiah K, Annapureddy AR, Khera R, Lansky A, Curtis JP. Characteristics of cardiac catheterization laboratory directors at the 2017 U.S. News & World Report top 100 U.S. cardiovascular hospitals Catheterization And Cardiovascular Interventions 2020, 97: e624-e626. PMID: 32833350, DOI: 10.1002/ccd.29217.
Digital Phenotyping of Myocardial Dysfunction With 12-Lead ECG Tiptoeing Into the Future With Machine Learning ∗Nasir K, Khera R. Digital Phenotyping of Myocardial Dysfunction With 12-Lead ECG Tiptoeing Into the Future With Machine Learning ∗ Journal Of The American College Of Cardiology 2020, 76: 942-944. PMID: 32819468, DOI: 10.1016/j.jacc.2020.07.001.
Financial Hardship After Traumatic Injury: Risk Factors and Drivers of Out-of-Pocket Health ExpensesO'Neill KM, Jean RA, Gross CP, Becher RD, Khera R, Elizondo JV, Nasir K. Financial Hardship After Traumatic Injury: Risk Factors and Drivers of Out-of-Pocket Health Expenses Journal Of Surgical Research 2020, 256: 1-12. PMID: 32663705, DOI: 10.1016/j.jss.2020.05.095.
The Promise of Big Data and Digital Solutions in Building a Cardiovascular Learning System: Opportunities and Barriers.Mori M, Khera R, Lin Z, Ross JS, Schulz W, Krumholz HM. The Promise of Big Data and Digital Solutions in Building a Cardiovascular Learning System: Opportunities and Barriers. Methodist DeBakey Cardiovascular Journal 2020, 16: 212-219. PMID: 33133357, PMCID: PMC7587314, DOI: 10.14797/mdcj-16-3-212.
Rates and Predictors of Patient Underreporting of Hospitalizations During Follow-Up After Acute Myocardial InfarctionCaraballo C, Khera R, Jones PG, Decker C, Schulz W, Spertus JA, Krumholz HM. Rates and Predictors of Patient Underreporting of Hospitalizations During Follow-Up After Acute Myocardial Infarction Circulation Cardiovascular Quality And Outcomes 2020, 13: e006231. PMID: 32552061, PMCID: PMC9465954, DOI: 10.1161/circoutcomes.119.006231.
Prevalence and Effects of Food Insecurity and Social Support on Financial Toxicity in and Healthcare Use by Patients With Inflammatory Bowel DiseasesNguyen NH, Khera R, Ohno-Machado L, Sandborn WJ, Singh S. Prevalence and Effects of Food Insecurity and Social Support on Financial Toxicity in and Healthcare Use by Patients With Inflammatory Bowel Diseases Clinical Gastroenterology And Hepatology 2020, 19: 1377-1386.e5. PMID: 32526341, PMCID: PMC7987215, DOI: 10.1016/j.cgh.2020.05.056.
An Evaluation of the Vulnerable Physician Workforce in the USA During the Coronavirus Disease-19 PandemicKhera R, Dhingra LS, Jain S, Krumholz HM. An Evaluation of the Vulnerable Physician Workforce in the USA During the Coronavirus Disease-19 Pandemic Journal Of General Internal Medicine 2020, 35: 3114-3116. PMID: 32495101, PMCID: PMC7269617, DOI: 10.1007/s11606-020-05854-7.
Association of cardiovascular risk factor profile and financial hardship from medical bills among non-elderly adults in the United StatesGrandhi GR, Valero-Elizondo J, Mszar R, Brandt EJ, Annapureddy A, Khera R, Saxena A, Virani SS, Blankstein R, Desai NR, Blaha MJ, Cheema FH, Vahidy FS, Nasir K. Association of cardiovascular risk factor profile and financial hardship from medical bills among non-elderly adults in the United States American Journal Of Preventive Cardiology 2020, 2: 100034. PMID: 34327457, PMCID: PMC8315456, DOI: 10.1016/j.ajpc.2020.100034.
Association of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease-19.Khera R, Clark C, Lu Y, Guo Y, Ren S, Truax B, Spatz ES, Murugiah K, Lin Z, Omer SB, Vojta D, Krumholz HM. Association of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease-19. MedRxiv : The Preprint Server For Health Sciences 2020 PMID: 32511481, PMCID: PMC7273249, DOI: 10.1101/2020.05.17.20104943.
Cumulative Burden of Financial Hardship From Medical Bills Across the Spectrum of Diabetes Mellitus and Atherosclerotic Cardiovascular Disease Among Non‐Elderly Adults in the United StatesMszar R, Grandhi GR, Valero‐Elizondo J, Caraballo C, Khera R, Desai N, Virani SS, Blankstein R, Blaha MJ, Nasir K. Cumulative Burden of Financial Hardship From Medical Bills Across the Spectrum of Diabetes Mellitus and Atherosclerotic Cardiovascular Disease Among Non‐Elderly Adults in the United States Journal Of The American Heart Association 2020, 9: e015523. PMID: 32394783, PMCID: PMC7660844, DOI: 10.1161/jaha.119.015523.
Do or Do Not, There Is No TryKhera R. Do or Do Not, There Is No Try Circulation Cardiovascular Quality And Outcomes 2020, 13: e006693. PMID: 32393124, DOI: 10.1161/circoutcomes.120.006693.
Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Replacement—Effective in Stroke Prevention?Khera R, Girotra S. Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Replacement—Effective in Stroke Prevention? JAMA Internal Medicine 2020, 180: 785-786. PMID: 32091530, DOI: 10.1001/jamainternmed.2019.6763.
Availability of Telemedicine Services Across Hospitals in the United States in 2018: A Cross-sectional StudyJain S, Khera R, Lin Z, Ross JS, Krumholz HM. Availability of Telemedicine Services Across Hospitals in the United States in 2018: A Cross-sectional Study Annals Of Internal Medicine 2020, 173: m20-1201. PMID: 32353106, PMCID: PMC7212823, DOI: 10.7326/m20-1201.
Evaluation of the Anticipated Burden of COVID-19 on Hospital-Based Healthcare Services Across the United States.Khera R, Jain S, Lin Z, Ross JS, Krumholz H. Evaluation of the Anticipated Burden of COVID-19 on Hospital-Based Healthcare Services Across the United States. MedRxiv : The Preprint Server For Health Sciences 2020 PMID: 32511584, PMCID: PMC7276011, DOI: 10.1101/2020.04.01.20050492.
An Evaluation of the Vulnerable Physician Workforce in the United States During the Coronavirus Disease-19 Pandemic.Khera R, Dhingra LS, Jain S, Krumholz H. An Evaluation of the Vulnerable Physician Workforce in the United States During the Coronavirus Disease-19 Pandemic. MedRxiv : The Preprint Server For Health Sciences 2020 PMID: 32511623, PMCID: PMC7276050, DOI: 10.1101/2020.03.26.20044263.
Abstract P559: National Burden & Cardiovascular Risk Factor Profile of Stroke Among Young Adults in The United StatesValero Elizondo J, Khera R, Vahidy F, Dubey P, Warraich H, Mahajan S, Blaha M, Blankstein R, Virani S, Cainzos Achirica M, Kash B, Krumholz H, Nasir K. Abstract P559: National Burden & Cardiovascular Risk Factor Profile of Stroke Among Young Adults in The United States Circulation 2020, 141 DOI: 10.1161/circ.141.suppl_1.p559.
VARIATION IN CARE PRACTICES FOR ACUTE MYOCARDIAL INFARCTION WITH MULTIVESSEL CORONARY ARTERY DISEASE PRESENTING WITH CARDIOGENIC SHOCK IN THE UNITED STATES, 2009-2018: A REPORT FROM THE NCDR RESEARCH TO PRACTICE (R2P) INITIATIVEKhera R, Secemsky E, Wang Y, Desai N, Maddox T, Shunk K, Virani S, Bhatt D, Curtis J, Yeh R. VARIATION IN CARE PRACTICES FOR ACUTE MYOCARDIAL INFARCTION WITH MULTIVESSEL CORONARY ARTERY DISEASE PRESENTING WITH CARDIOGENIC SHOCK IN THE UNITED STATES, 2009-2018: A REPORT FROM THE NCDR RESEARCH TO PRACTICE (R2P) INITIATIVE Journal Of The American College Of Cardiology 2020, 75: 1126. DOI: 10.1016/s0735-1097(20)31753-8.
COST, RESOURCE UTILIZATION, QUALITY OF LIFE, MENTAL HEALTH, AND FINANCIAL TOXICITY AMONG YOUNG ADULTS WITH STROKE IN THE UNITED STATESElizondo J, Khera R, Vahidy F, Warraich H, Mahajan S, Blaha M, Blankstein R, Virani S, Achirica M, Kash B, Krumholz H, Nasir K. COST, RESOURCE UTILIZATION, QUALITY OF LIFE, MENTAL HEALTH, AND FINANCIAL TOXICITY AMONG YOUNG ADULTS WITH STROKE IN THE UNITED STATES Journal Of The American College Of Cardiology 2020, 75: 1838. DOI: 10.1016/s0735-1097(20)32465-7.
TEMPORAL TRENDS AND CONTEMPORARY USE OF MULTIVESSEL PERCUTANEOUS CORONARY REVASCULARIZATION FOR ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION IN THE US: AN NCDR RESEARCH TO PRACTICE (R2P) PROJECTSecemsky E, Khera R, Maddox T, Bhatt D, Armstrong E, Curtis J, Bao H, Yeh R. TEMPORAL TRENDS AND CONTEMPORARY USE OF MULTIVESSEL PERCUTANEOUS CORONARY REVASCULARIZATION FOR ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION IN THE US: AN NCDR RESEARCH TO PRACTICE (R2P) PROJECT Journal Of The American College Of Cardiology 2020, 75: 1128. DOI: 10.1016/s0735-1097(20)31755-1.
Burden and Consequences of Financial Hardship From Medical Bills Among Nonelderly Adults With Diabetes Mellitus in the United StatesCaraballo C, Valero-Elizondo J, Khera R, Mahajan S, Grandhi GR, Virani SS, Mszar R, Krumholz HM, Nasir K. Burden and Consequences of Financial Hardship From Medical Bills Among Nonelderly Adults With Diabetes Mellitus in the United States Circulation Cardiovascular Quality And Outcomes 2020, 13: e006139. PMID: 32069093, DOI: 10.1161/circoutcomes.119.006139.
Readmission and Mortality After Hospitalization for Myocardial Infarction and Heart FailureKo DT, Khera R, Lau G, Qiu F, Wang Y, Austin PC, Koh M, Lin Z, Lee DS, Wijeysundera HC, Krumholz HM. Readmission and Mortality After Hospitalization for Myocardial Infarction and Heart Failure Journal Of The American College Of Cardiology 2020, 75: 736-746. PMID: 32081282, DOI: 10.1016/j.jacc.2019.12.026.
Temporal Trends in Racial Differences in 30-Day Readmission and Mortality Rates After Acute Myocardial Infarction Among Medicare BeneficiariesPandey A, Keshvani N, Khera R, Lu D, Vaduganathan M, Maddox K, Das SR, Kumbhani DJ, Goyal A, Girotra S, Chan P, Fonarow GC, Matsouaka R, Wang TY, de Lemos JA. Temporal Trends in Racial Differences in 30-Day Readmission and Mortality Rates After Acute Myocardial Infarction Among Medicare Beneficiaries JAMA Cardiology 2020, 5: 136-145. PMID: 31913411, PMCID: PMC6990949, DOI: 10.1001/jamacardio.2019.4845.
Post-discharge acute care and outcomes following readmission reduction initiatives: national retrospective cohort study of Medicare beneficiaries in the United StatesKhera R, Wang Y, Bernheim SM, Lin Z, Krumholz HM. Post-discharge acute care and outcomes following readmission reduction initiatives: national retrospective cohort study of Medicare beneficiaries in the United States The BMJ 2020, 368: l6831. PMID: 31941686, PMCID: PMC7190056, DOI: 10.1136/bmj.l6831.
Variation and Disparities in Awareness of Myocardial Infarction Symptoms Among Adults in the United StatesMahajan S, Valero-Elizondo J, Khera R, Desai NR, Blankstein R, Blaha MJ, Virani SS, Kash BA, Zoghbi WA, Krumholz HM, Nasir K. Variation and Disparities in Awareness of Myocardial Infarction Symptoms Among Adults in the United States JAMA Network Open 2019, 2: e1917885. PMID: 31851350, PMCID: PMC6991230, DOI: 10.1001/jamanetworkopen.2019.17885.
Cost-Related Medication Nonadherence in Adults With Atherosclerotic Cardiovascular Disease in the United States, 2013 to 2017Khera R, Valero-Elizondo J, Das SR, Virani SS, Kash BA, de Lemos JA, Krumholz HM, Nasir K. Cost-Related Medication Nonadherence in Adults With Atherosclerotic Cardiovascular Disease in the United States, 2013 to 2017 Circulation 2019, 140: 2067-2075. PMID: 31760784, DOI: 10.1161/circulationaha.119.041974.
Machine Learning Prediction of Mortality and Hospitalization in Heart Failure With Preserved Ejection FractionAngraal S, Mortazavi BJ, Gupta A, Khera R, Ahmad T, Desai NR, Jacoby DL, Masoudi FA, Spertus JA, Krumholz HM. Machine Learning Prediction of Mortality and Hospitalization in Heart Failure With Preserved Ejection Fraction JACC Heart Failure 2019, 8: 12-21. PMID: 31606361, DOI: 10.1016/j.jchf.2019.06.013.
Hemodynamic Phenotypes of Hypertension Based on Cardiac Output and Systemic Vascular ResistanceMahajan S, Gu J, Lu Y, Khera R, Spatz ES, Zhang M, Sun N, Zheng X, Zhao H, Lu H, Ma ZJ, Krumholz HM. Hemodynamic Phenotypes of Hypertension Based on Cardiac Output and Systemic Vascular Resistance The American Journal Of Medicine 2019, 133: e127-e139. PMID: 31525336, DOI: 10.1016/j.amjmed.2019.08.042.
National Trends in Healthcare-Associated Infections for Five Common Cardiovascular ConditionsMiller PE, Guha A, Khera R, Chouairi F, Ahmad T, Nasir K, Addison D, Desai NR. National Trends in Healthcare-Associated Infections for Five Common Cardiovascular Conditions The American Journal Of Cardiology 2019, 124: 1140-1148. PMID: 31371062, PMCID: PMC7883647, DOI: 10.1016/j.amjcard.2019.06.029.
Evaluation of 30-Day Hospital Readmission and Mortality Rates Using Regression-Discontinuity FrameworkKhera R, Wang Y, Nasir K, Lin Z, Krumholz HM. Evaluation of 30-Day Hospital Readmission and Mortality Rates Using Regression-Discontinuity Framework Journal Of The American College Of Cardiology 2019, 74: 219-234. PMID: 31296295, PMCID: PMC8669780, DOI: 10.1016/j.jacc.2019.04.060.
Diagnostic and prognostic utility of cardiac troponin in post-cardiac arrest careAgusala V, Khera R, Cheeran D, Mody P, Reddy PP, Link MS. Diagnostic and prognostic utility of cardiac troponin in post-cardiac arrest care Resuscitation 2019, 141: 69-72. PMID: 31201884, DOI: 10.1016/j.resuscitation.2019.06.004.
Cost-minimization study of the percutaneous approach to endovascular aortic aneurysm repairHong JC, Yang GK, Delarmente BA, Khera R, Price J, Faulds J, Chen JC. Cost-minimization study of the percutaneous approach to endovascular aortic aneurysm repair Journal Of Vascular Surgery 2019, 71: 444-449. PMID: 31176637, DOI: 10.1016/j.jvs.2019.03.040.
Targeted temperature management for cardiac arrestMody P, Kulkarni N, Khera R, Link MS. Targeted temperature management for cardiac arrest Progress In Cardiovascular Diseases 2019, 62: 272-278. PMID: 31078561, DOI: 10.1016/j.pcad.2019.05.007.
Financial Toxicity of Acute Cardiovascular Disease in IndiaNasir K, Khera R. Financial Toxicity of Acute Cardiovascular Disease in India JAMA Network Open 2019, 2: e193839. PMID: 31099855, DOI: 10.1001/jamanetworkopen.2019.3839.
Pulselessness After Initiation of Cardiopulmonary Resuscitation for Bradycardia in Hospitalized ChildrenKhera R, Tang Y, Girotra S, Nadkarni VM, Link MS, Raymond TT, Guerguerian AM, Berg RA, Chan PS, Investigators F. Pulselessness After Initiation of Cardiopulmonary Resuscitation for Bradycardia in Hospitalized Children Circulation 2019, 140: 370-378. PMID: 31006260, PMCID: PMC6663562, DOI: 10.1161/circulationaha.118.039048.
Administrative Billing Codes for Identifying Patients With Cardiac ArrestDeZorzi C, Boyle B, Qazi A, Luthra K, Khera R, Chan PS, Girotra S. Administrative Billing Codes for Identifying Patients With Cardiac Arrest Journal Of The American College Of Cardiology 2019, 73: 1598-1600. PMID: 30922482, PMCID: PMC6625314, DOI: 10.1016/j.jacc.2019.01.030.
Abstract 157: Assessment of Financial Hardship From Medical Bills Across the Spectrum of Diabetes Mellitus and Atherosclerotic Cardiovascular Disease Among Non-Elderly Adults in the United StatesMszar R, Grandhi G, Valero-Elizondo J, Khera R, Desai N, Virani S, Blankstein R, Blaha M, Nasir K. Abstract 157: Assessment of Financial Hardship From Medical Bills Across the Spectrum of Diabetes Mellitus and Atherosclerotic Cardiovascular Disease Among Non-Elderly Adults in the United States Circulation Cardiovascular Quality And Outcomes 2019, 12 DOI: 10.1161/hcq.12.suppl_1.157.
Association of Access to exercise opportunities and cardiovascular mortalityAngraal S, Gupta A, Khera R, Nasir K, Desai NR. Association of Access to exercise opportunities and cardiovascular mortality American Heart Journal 2019, 212: 152-156. PMID: 31051426, DOI: 10.1016/j.ahj.2019.02.010.
Association Between Hospital Recognition for Resuscitation Guideline Adherence and Rates of Survival for In-Hospital Cardiac ArrestKhera R, Tang Y, Link MS, Krumholz HM, Girotra S, Chan PS. Association Between Hospital Recognition for Resuscitation Guideline Adherence and Rates of Survival for In-Hospital Cardiac Arrest Circulation Cardiovascular Quality And Outcomes 2019, 12: e005429. PMID: 30871337, PMCID: PMC6592630, DOI: 10.1161/circoutcomes.118.005429.
Effect of Neutropenic Diet on Infection Rates in Cancer Patients With NeutropeniaBall S, Brown TJ, Das A, Khera R, Khanna S, Gupta A. Effect of Neutropenic Diet on Infection Rates in Cancer Patients With Neutropenia American Journal Of Clinical Oncology 2019, 42: 270-274. PMID: 30628912, DOI: 10.1097/coc.0000000000000514.
ARE US HOSPITALS GAMING THE HOSPITAL READMISSIONS REDUCTION PROGRAM? AN EVALUATION OF 30-DAY READMISSIONS AND MORTALITY FOR TARGET CARDIOVASCULAR CONDITIONS USING A REGRESSION-DISCONTINUITY FRAMEWORKKhera R, Wang Y, Nasir K, Lin Z, Krumholz H. ARE US HOSPITALS GAMING THE HOSPITAL READMISSIONS REDUCTION PROGRAM? AN EVALUATION OF 30-DAY READMISSIONS AND MORTALITY FOR TARGET CARDIOVASCULAR CONDITIONS USING A REGRESSION-DISCONTINUITY FRAMEWORK Journal Of The American College Of Cardiology 2019, 73: 3079. DOI: 10.1016/s0735-1097(19)33685-x.
IDENTIFICATION OF CENTERS OF EXCELLENCE FOR TAVR: AN ASSESSMENT OF THE CURRENT PARADIGM BASED ON PROCEDURE VOLUMESKhera R, Kennedy K, Das S, Kundi H, Strom J, Popma J, Yeh R. IDENTIFICATION OF CENTERS OF EXCELLENCE FOR TAVR: AN ASSESSMENT OF THE CURRENT PARADIGM BASED ON PROCEDURE VOLUMES Journal Of The American College Of Cardiology 2019, 73: 1376. DOI: 10.1016/s0735-1097(19)31983-7.
TRENDS IN RACIAL DIFFERENCES IN 30-DAY READMISSION RATE FOR ACUTE MYOCARDIAL INFARCTION: AN ANALYSIS FROM THE NCDR CHEST PAIN-MI REGISTRYPandey A, Khera R, Lu D, Vaduganathan M, Maddox K, Das S, Kumbhani D, Goyal A, Girotra S, Chan P, Fonarow G, Matsouaka R, Wang T, de Lemos J. TRENDS IN RACIAL DIFFERENCES IN 30-DAY READMISSION RATE FOR ACUTE MYOCARDIAL INFARCTION: AN ANALYSIS FROM THE NCDR CHEST PAIN-MI REGISTRY Journal Of The American College Of Cardiology 2019, 73: 260. DOI: 10.1016/s0735-1097(19)30868-x.
Association of Income Disparities with Patient-Reported Healthcare ExperienceOkunrintemi V, Khera R, Spatz ES, Salami JA, Valero-Elizondo J, Warraich HJ, Virani SS, Blankstein R, Blaha MJ, Pawlik TM, Dharmarajan K, Krumholz HM, Nasir K. Association of Income Disparities with Patient-Reported Healthcare Experience Journal Of General Internal Medicine 2019, 34: 884-892. PMID: 30783877, PMCID: PMC6544715, DOI: 10.1007/s11606-019-04848-4.
Financial Hardship From Medical Bills Among Nonelderly U.S. Adults With Atherosclerotic Cardiovascular DiseaseValero-Elizondo J, Khera R, Saxena A, Grandhi GR, Virani SS, Butler J, Samad Z, Desai NR, Krumholz HM, Nasir K. Financial Hardship From Medical Bills Among Nonelderly U.S. Adults With Atherosclerotic Cardiovascular Disease Journal Of The American College Of Cardiology 2019, 73: 727-732. PMID: 30765039, DOI: 10.1016/j.jacc.2018.12.004.
Education level and outcomes after acute myocardial infarction in ChinaHuo X, Khera R, Zhang L, Herrin J, Bai X, Wang Q, Lu Y, Nasir K, Hu S, Li J, Li X, Zheng X, Masoudi FA, Spertus JA, Krumholz HM, Jiang L. Education level and outcomes after acute myocardial infarction in China Heart 2019, 105: 946. PMID: 30661037, PMCID: PMC6582708, DOI: 10.1136/heartjnl-2018-313752.
Effects of the Hospital Readmissions Reduction ProgramKhera R, Krumholz HM. Effects of the Hospital Readmissions Reduction Program Circulation Cardiovascular Quality And Outcomes 2018, 11: e005083. PMID: 30562071, DOI: 10.1161/circoutcomes.118.005083.
Managing Implantable Cardioverter-Defibrillators at End-of-Life: Practical Challenges and Care ConsiderationsKhera R, Pandey A, Link MS, Sulistio MS. Managing Implantable Cardioverter-Defibrillators at End-of-Life: Practical Challenges and Care Considerations The American Journal Of The Medical Sciences 2018, 357: 143-150. PMID: 30665495, DOI: 10.1016/j.amjms.2018.11.016.
Abstract 108: Pulselessness Despite Cardiopulmonary Resuscitation for Bradycardia in Hospitalized Children: Prevalence, Predictors of Survival, and Implications for Hospital ProfilingKhera R, Tang Y, Girotra S, Nadkarni V, Link M, Raymond T, Guerguerian A, Berg R, Chan P. Abstract 108: Pulselessness Despite Cardiopulmonary Resuscitation for Bradycardia in Hospitalized Children: Prevalence, Predictors of Survival, and Implications for Hospital Profiling Circulation 2018, 138 DOI: 10.1161/circ.138.suppl_2.108.
Abstract 20: Intraosseous vs. Intravenously Administered Advanced Life Support Drugs in Patients With Out-of-Hospital Cardiac Arrest: Insights From the Resuscitation Outcomes Consortium Continuous Chest Compression TrialMody P, Brown S, Khera R, Pandey A, Ayers C, Kudenchuk P, Chan P, de Lemos J, Kern K, Link M, Idris A. Abstract 20: Intraosseous vs. Intravenously Administered Advanced Life Support Drugs in Patients With Out-of-Hospital Cardiac Arrest: Insights From the Resuscitation Outcomes Consortium Continuous Chest Compression Trial Circulation 2018, 138 DOI: 10.1161/circ.138.suppl_2.20.
Abstract 24: Sex Differences in Outcomes After Out-of-Hospital Cardiac Arrest Patients: Insights From the Resuscitation Outcomes Consortium Continuous Chest Compression TrialMody P, Pandey A, Khera R, Ayers C, Link M, Idris A. Abstract 24: Sex Differences in Outcomes After Out-of-Hospital Cardiac Arrest Patients: Insights From the Resuscitation Outcomes Consortium Continuous Chest Compression Trial Circulation 2018, 138 DOI: 10.1161/circ.138.suppl_2.24.
Association Between Financial Burden, Quality of Life, and Mental Health Among Those With Atherosclerotic Cardiovascular Disease in the United StatesAnnapureddy A, Valero-Elizondo J, Khera R, Grandhi GR, Spatz ES, Dreyer RP, Desai NR, Krumholz HM, Nasir K. Association Between Financial Burden, Quality of Life, and Mental Health Among Those With Atherosclerotic Cardiovascular Disease in the United States Circulation Cardiovascular Quality And Outcomes 2018, 11: e005180. PMID: 30571331, DOI: 10.1161/circoutcomes.118.005180.
Intraosseous versus intravenous access in patients with out-of-hospital cardiac arrest: Insights from the resuscitation outcomes consortium continuous chest compression trialMody P, Brown SP, Kudenchuk PJ, Chan PS, Khera R, Ayers C, Pandey A, Kern K, de Lemos JA, Link MS, Idris AH. Intraosseous versus intravenous access in patients with out-of-hospital cardiac arrest: Insights from the resuscitation outcomes consortium continuous chest compression trial Resuscitation 2018, 134: 69-75. PMID: 30391366, DOI: 10.1016/j.resuscitation.2018.10.031.
Hospital Variation in the Utilization and Implementation of Targeted Temperature Management in Out-of-Hospital Cardiac ArrestKhera R, Humbert A, Leroux B, Nichol G, Kudenchuk P, Scales D, Baker A, Austin M, Newgard CD, Radecki R, Vilke GM, Sawyer KN, Sopko G, Idris AH, Wang H, Chan PS, Kurz MC. Hospital Variation in the Utilization and Implementation of Targeted Temperature Management in Out-of-Hospital Cardiac Arrest Circulation Cardiovascular Quality And Outcomes 2018, 11: e004829. PMID: 30571336, DOI: 10.1161/circoutcomes.118.004829.
Early coronary angiography and survival after out-of-hospital cardiac arrest: a systematic review and meta-analysisKhera R, CarlLee S, Blevins A, Schweizer M, Girotra S. Early coronary angiography and survival after out-of-hospital cardiac arrest: a systematic review and meta-analysis Open Heart 2018, 5: e000809. PMID: 30402255, PMCID: PMC6203043, DOI: 10.1136/openhrt-2018-000809.
Readmissions of adults within three age groups following hospitalization for pneumonia: Analysis from the Nationwide Readmissions DatabaseJain S, Khera R, Mortensen EM, Weissler JC. Readmissions of adults within three age groups following hospitalization for pneumonia: Analysis from the Nationwide Readmissions Database PLOS ONE 2018, 13: e0203375. PMID: 30212485, PMCID: PMC6136736, DOI: 10.1371/journal.pone.0203375.
Trends in 30-Day Readmission Rates for Medicare and Non-Medicare Patients in the Era of the Affordable Care ActAngraal S, Khera R, Zhou S, Wang Y, Lin Z, Dharmarajan K, Desai NR, Bernheim SM, Drye EE, Nasir K, Horwitz LI, Krumholz HM. Trends in 30-Day Readmission Rates for Medicare and Non-Medicare Patients in the Era of the Affordable Care Act The American Journal Of Medicine 2018, 131: 1324-1331.e14. PMID: 30016636, PMCID: PMC6380174, DOI: 10.1016/j.amjmed.2018.06.013.
Association of the Hospital Readmissions Reduction Program With Mortality During and After Hospitalization for Acute Myocardial Infarction, Heart Failure, and PneumoniaKhera R, Dharmarajan K, Wang Y, Lin Z, Bernheim SM, Wang Y, Normand ST, Krumholz HM. Association of the Hospital Readmissions Reduction Program With Mortality During and After Hospitalization for Acute Myocardial Infarction, Heart Failure, and Pneumonia JAMA Network Open 2018, 1: e182777. PMID: 30646181, PMCID: PMC6324473, DOI: 10.1001/jamanetworkopen.2018.2777.
Increasing Sepsis Rates in the United States: Results From National Inpatient Sample, 2005 to 2014Rubens M, Saxena A, Ramamoorthy V, Das S, Khera R, Hong J, Armaignac D, Veledar E, Nasir K, Gidel L. Increasing Sepsis Rates in the United States: Results From National Inpatient Sample, 2005 to 2014 Journal Of Intensive Care Medicine 2018, 35: 858-868. PMID: 30175649, DOI: 10.1177/0885066618794136.
Percutaneous Approach to Endovascular Aortic Aneurysm Repair: A Cost-Minimization StudyHong J, Yang G, Delmarte B, Khera R, Price J, Chen J. Percutaneous Approach to Endovascular Aortic Aneurysm Repair: A Cost-Minimization Study Journal Of Vascular Surgery 2018, 68: e74-e75. DOI: 10.1016/j.jvs.2018.06.152.
Percutaneous Approach to Endovascular Aortic Aneurysm Repair: A Cost-Minimization StudyHong J, Yang G, Delarmente B, Khera R, Price J, Chen J. Percutaneous Approach to Endovascular Aortic Aneurysm Repair: A Cost-Minimization Study Journal Of Vascular Surgery 2018, 68: e38. DOI: 10.1016/j.jvs.2018.06.087.
Comparison of Outcomes of Transfemoral Versus Transapical Approach for Transcatheter Aortic Valve ImplantationKumar N, Khera R, Fonarow GC, Bhatt DL. Comparison of Outcomes of Transfemoral Versus Transapical Approach for Transcatheter Aortic Valve Implantation The American Journal Of Cardiology 2018, 122: 1520-1526. PMID: 30190074, DOI: 10.1016/j.amjcard.2018.07.025.
Association of Out-of-Pocket Annual Health Expenditures With Financial Hardship in Low-Income Adults With Atherosclerotic Cardiovascular Disease in the United StatesKhera R, Valero-Elizondo J, Okunrintemi V, Saxena A, Das SR, de Lemos JA, Krumholz HM, Nasir K. Association of Out-of-Pocket Annual Health Expenditures With Financial Hardship in Low-Income Adults With Atherosclerotic Cardiovascular Disease in the United States JAMA Cardiology 2018, 3: 729-738. PMID: 29971325, PMCID: PMC6143078, DOI: 10.1001/jamacardio.2018.1813.
P263Validity of administrative billing codes for identifying patients with cardiac arrestDezorzi C, Boyle B, Qazi A, Khera R, Chan P, Girotra S. P263Validity of administrative billing codes for identifying patients with cardiac arrest European Heart Journal 2018, 39 DOI: 10.1093/eurheartj/ehy564.p263.
Sex and Race Differences in the Utilization and Outcomes of Coronary Artery Bypass Grafting Among Medicare Beneficiaries, 1999–2014Angraal S, Khera R, Wang Y, Lu Y, Jean R, Dreyer RP, Geirsson A, Desai NR, Krumholz HM. Sex and Race Differences in the Utilization and Outcomes of Coronary Artery Bypass Grafting Among Medicare Beneficiaries, 1999–2014 Journal Of The American Heart Association 2018, 7: e009014. PMID: 30005557, PMCID: PMC6064835, DOI: 10.1161/jaha.118.009014.
Impact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional studyKhera R, Lu Y, Lu J, Saxena A, Nasir K, Jiang L, Krumholz HM. Impact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study The BMJ 2018, 362: k2357. PMID: 29997129, PMCID: PMC6039831, DOI: 10.1136/bmj.k2357.
Transition to the ICD-10 in the United States: An Emerging Data ChasmKhera R, Dorsey KB, Krumholz HM. Transition to the ICD-10 in the United States: An Emerging Data Chasm JAMA 2018, 320: 133-134. PMID: 29868861, DOI: 10.1001/jama.2018.6823.
Rising Mortality in Patients With Heart Failure in the United States Facts Versus FictionKhera R, Dharmarajan K, Krumholz HM. Rising Mortality in Patients With Heart Failure in the United States Facts Versus Fiction JACC Heart Failure 2018, 6: 610-612. PMID: 29914774, DOI: 10.1016/j.jchf.2018.02.011.
Trends in Use and Expenditures of Brand-name Atorvastatin After Introduction of Generic AtorvastatinWarraich HJ, Salami JA, Khera R, Valero-Elizondo J, Okunrintemi V, Nasir K. Trends in Use and Expenditures of Brand-name Atorvastatin After Introduction of Generic Atorvastatin JAMA Internal Medicine 2018, 178: 719-721. PMID: 29525818, PMCID: PMC5885171, DOI: 10.1001/jamainternmed.2018.0990.
Usefulness of a Simple Algorithm to Identify Hypertensive Patients Who Benefit from Intensive Blood Pressure LoweringWang S, Khera R, Das SR, Vigen R, Wang T, Luo X, Lu R, Zhan X, Xiao G, Vongpatanasin W, Xie Y. Usefulness of a Simple Algorithm to Identify Hypertensive Patients Who Benefit from Intensive Blood Pressure Lowering The American Journal Of Cardiology 2018, 122: 248-254. PMID: 29880288, DOI: 10.1016/j.amjcard.2018.03.361.
Abstract 279: Eligibility and Cost Estimates for Anti-inflammatory Therapy for Atherosclerotic Disease: Implications of the CANTOS Trial for the US Adult PopulationKhera R, Saxena A, Hong J, Arrieta A, Ross J, Krumholz H, Nasir K. Abstract 279: Eligibility and Cost Estimates for Anti-inflammatory Therapy for Atherosclerotic Disease: Implications of the CANTOS Trial for the US Adult Population Circulation Cardiovascular Quality And Outcomes 2018, 11 DOI: 10.1161/circoutcomes.11.suppl_1.279.
Abstract 209: Education Level and Long-Term Outcomes After Acute Myocardial Infarction: The China PEACE Prospective AMI StudyHuo X, Khera R, Zhang L, Wang Q, Herrin J, Lu Y, Nasir K, Hu S, Li J, Li X, Zheng X, Masoudi F, Spertus J, Krumholz H, Jiang L. Abstract 209: Education Level and Long-Term Outcomes After Acute Myocardial Infarction: The China PEACE Prospective AMI Study Circulation Cardiovascular Quality And Outcomes 2018, 11 DOI: 10.1161/circoutcomes.11.suppl_1.209.
Abstract 2: Financial Toxicity From Out-of-pocket Annual Health Expenditures in Low-income Adults With Atherosclerotic Cardiovascular Disease in the United StatesKhera R, Valero-Elizondo J, Okunrintemi V, Saxena A, de Lemos J, Krumholz H, Nasir K. Abstract 2: Financial Toxicity From Out-of-pocket Annual Health Expenditures in Low-income Adults With Atherosclerotic Cardiovascular Disease in the United States Circulation Cardiovascular Quality And Outcomes 2018, 11 DOI: 10.1161/circoutcomes.11.suppl_1.2.
Abstract 281: Contemporary Epidemiology of Atrial Fibrillation Among Medicare Beneficiaries, 2004-2013Parker J, Khera R, Pandey A, Cheeran D, Ayers C, Das S, Link M, de Lemos J, Berry J. Abstract 281: Contemporary Epidemiology of Atrial Fibrillation Among Medicare Beneficiaries, 2004-2013 Circulation Cardiovascular Quality And Outcomes 2018, 11 DOI: 10.1161/circoutcomes.11.suppl_1.281.
Publicly Reported Readmission Measures and the Hospital Readmissions Reduction Program: A False Equivalence?Khera R, Horwitz LI, Lin Z, Krumholz HM. Publicly Reported Readmission Measures and the Hospital Readmissions Reduction Program: A False Equivalence? Annals Of Internal Medicine 2018, 168: 670-671. PMID: 29582081, PMCID: PMC8325174, DOI: 10.7326/m18-0536.
EXCESS NATIONAL US EXPENDITURES ASSOCIATED WITH LIPITOR USE AFTER INTRODUCTION OF GENERIC ATORVASTATIN: INSIGHTS FROM THE MEDICAL EXPENDITURES PANEL SURVEY, 2012-2014Warraich H, Salami J, Khera R, Okunrintemi V, Nasir K. EXCESS NATIONAL US EXPENDITURES ASSOCIATED WITH LIPITOR USE AFTER INTRODUCTION OF GENERIC ATORVASTATIN: INSIGHTS FROM THE MEDICAL EXPENDITURES PANEL SURVEY, 2012-2014 Journal Of The American College Of Cardiology 2018, 71: a1764. DOI: 10.1016/s0735-1097(18)32305-2.
INTRAVENOUS VERSUS INTRAOSSEOUS ACCESS FOR PARENTERAL DRUG ADMINISTRATION IN OUT-OF-HOSPITAL CARDIAC ARRESTMody P, Khera R, Patel N, Owens P, Berry J, Link M, Idris A. INTRAVENOUS VERSUS INTRAOSSEOUS ACCESS FOR PARENTERAL DRUG ADMINISTRATION IN OUT-OF-HOSPITAL CARDIAC ARREST Journal Of The American College Of Cardiology 2018, 71: a457. DOI: 10.1016/s0735-1097(18)30998-7.
PATIENT-PROVIDER RACIAL CONCORDANCE AND PATIENT REPORTED HEALTHCARE EXPERIENCE, AMONG ADULTS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASE: INSIGHTS FROM MEDICAL EXPENDITURE PANEL SURVEY, 2010-2013Okunrintemi V, Spatz E, Khera R, Salami J, Valero-Elizondo J, Ogunmoroti O, Ayinde H, Patrick B, Virani S, Blaha M, Blankstein R, Nasir K. PATIENT-PROVIDER RACIAL CONCORDANCE AND PATIENT REPORTED HEALTHCARE EXPERIENCE, AMONG ADULTS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASE: INSIGHTS FROM MEDICAL EXPENDITURE PANEL SURVEY, 2010-2013 Journal Of The American College Of Cardiology 2018, 71: a2641. DOI: 10.1016/s0735-1097(18)33182-6.
ACCURACY OF THE POOLED COHORT EQUATION TO ESTIMATE ATHEROSCLEROTIC CARDIOVASCULAR DISEASE EVENTS BY OBESITY CLASS: A POOLED ASSESSMENT OF FIVE LONGITUDINAL COHORT STUDIESKhera R, Pandey A, Ayers C, Carnethon M, Greenland P, Nambi V, Seliger S, Chaves P, Lloyd-Jones D, Berry J, de Lemos J, Neeland I. ACCURACY OF THE POOLED COHORT EQUATION TO ESTIMATE ATHEROSCLEROTIC CARDIOVASCULAR DISEASE EVENTS BY OBESITY CLASS: A POOLED ASSESSMENT OF FIVE LONGITUDINAL COHORT STUDIES Journal Of The American College Of Cardiology 2018, 71: a1738. DOI: 10.1016/s0735-1097(18)32279-4.
Annual Burden and Costs of Hospitalization for High-Need, High-Cost Patients With Chronic Gastrointestinal and Liver DiseasesNguyen NH, Khera R, Ohno-Machado L, Sandborn WJ, Singh S. Annual Burden and Costs of Hospitalization for High-Need, High-Cost Patients With Chronic Gastrointestinal and Liver Diseases Clinical Gastroenterology And Hepatology 2018, 16: 1284-1292.e30. PMID: 29474966, PMCID: PMC6056327, DOI: 10.1016/j.cgh.2018.02.015.
Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction A Study-Level Pooled AnalysisPandey A, Khera R, Park B, Haykowsky M, Borlaug BA, Lewis GD, Kitzman DW, Butler J, Berry JD. Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction A Study-Level Pooled Analysis JACC Heart Failure 2018, 6: 117-126. PMID: 29413366, PMCID: PMC8135913, DOI: 10.1016/j.jchf.2017.10.014.
Trends in Diabetes-Related Preventable Hospitalizations in the U.S., 2005–2014Rubens M, Saxena A, Ramamoorthy V, Khera R, Hong J, Veledar E, Nasir K. Trends in Diabetes-Related Preventable Hospitalizations in the U.S., 2005–2014 Diabetes Care 2018, 41: dc171942. PMID: 29378777, DOI: 10.2337/dc17-1942.
Effects of Weight-Loss Medications on Cardiometabolic Risk Profiles: A Systematic Review and Network Meta-analysisKhera R, Pandey A, Chandar AK, Murad MH, Prokop LJ, Neeland IJ, Berry JD, Camilleri M, Singh S. Effects of Weight-Loss Medications on Cardiometabolic Risk Profiles: A Systematic Review and Network Meta-analysis Gastroenterology 2018, 154: 1309-1319.e7. PMID: 29305933, PMCID: PMC5880739, DOI: 10.1053/j.gastro.2017.12.024.
Persistent socioeconomic disparities in cardiovascular risk factors and health in the United States: Medical Expenditure Panel Survey 2002–2013Valero-Elizondo J, Hong JC, Spatz ES, Salami JA, Desai NR, Rana JS, Khera R, Virani SS, Blankstein R, Blaha MJ, Nasir K. Persistent socioeconomic disparities in cardiovascular risk factors and health in the United States: Medical Expenditure Panel Survey 2002–2013 Atherosclerosis 2017, 269: 301-305. PMID: 29254694, DOI: 10.1016/j.atherosclerosis.2017.12.014.
Updated Cost-effectiveness Assessments of PCSK9 Inhibitors From the Perspectives of the Health System and Private Payers: Insights Derived From the FOURIER TrialArrieta A, Hong JC, Khera R, Virani SS, Krumholz HM, Nasir K. Updated Cost-effectiveness Assessments of PCSK9 Inhibitors From the Perspectives of the Health System and Private Payers: Insights Derived From the FOURIER Trial JAMA Cardiology 2017, 2: 1369-1374. PMID: 29049467, PMCID: PMC5814995, DOI: 10.1001/jamacardio.2017.3655.
Role of Hospital Volumes in Identifying Low-Performing and High-Performing Aortic and Mitral Valve Surgical Centers in the United StatesKhera R, Pandey A, Koshy T, Ayers C, Nallamothu BK, Das SR, Drazner MH, Jessen ME, Kirtane AJ, Gardner TJ, de Lemos JA, Bhatt DL, Kumbhani DJ. Role of Hospital Volumes in Identifying Low-Performing and High-Performing Aortic and Mitral Valve Surgical Centers in the United States JAMA Cardiology 2017, 2: 1322-1331. PMID: 29117319, PMCID: PMC5815001, DOI: 10.1001/jamacardio.2017.4003.
The heart failure readmission quagmire: taking a deep dive to find solutionsKhera R, Pandey A. The heart failure readmission quagmire: taking a deep dive to find solutions European Journal Of Heart Failure 2017, 20: 315-316. PMID: 29193571, DOI: 10.1002/ejhf.1082.
Adherence to Methodological Standards in Research Using the National Inpatient SampleKhera R, Angraal S, Couch T, Welsh JW, Nallamothu BK, Girotra S, Chan PS, Krumholz HM. Adherence to Methodological Standards in Research Using the National Inpatient Sample JAMA 2017, 318: 2011-2018. PMID: 29183077, PMCID: PMC5742631, DOI: 10.1001/jama.2017.17653.
Burden of Catastrophic Health Expenditures for Acute Myocardial Infarction and Stroke Among Uninsured in the United StatesKhera R, Hong JC, Saxena A, Arrieta A, Virani SS, Blankstein R, de Lemos JA, Krumholz HM, Nasir K. Burden of Catastrophic Health Expenditures for Acute Myocardial Infarction and Stroke Among Uninsured in the United States Circulation 2017, 137: 408-410. PMID: 29133601, PMCID: PMC5780190, DOI: 10.1161/circulationaha.117.030128.
Administrative Codes for Capturing In-Hospital Cardiac ArrestKhera R, Spertus JA, Starks MA, Tang Y, Bradley SM, Girotra S, Chan PS. Administrative Codes for Capturing In-Hospital Cardiac Arrest JAMA Cardiology 2017, 2: 1275-1277. PMID: 28877294, PMCID: PMC5736791, DOI: 10.1001/jamacardio.2017.2904.
Contemporary Epidemiology of Heart Failure in Fee-For-Service Medicare Beneficiaries Across Healthcare SettingsKhera R, Pandey A, Ayers CR, Agusala V, Pruitt SL, Halm EA, Drazner MH, Das SR, de Lemos JA, Berry JD. Contemporary Epidemiology of Heart Failure in Fee-For-Service Medicare Beneficiaries Across Healthcare Settings Circulation Heart Failure 2017, 10: e004402. PMID: 29129828, PMCID: PMC6057614, DOI: 10.1161/circheartfailure.117.004402.
Comparison of Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Chronic Kidney DiseaseKumar N, Khera R, Garg N, Echouffo-Tcheugui JB, Venkatraman A, Pandey A, Bhatt DL. Comparison of Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Chronic Kidney Disease The American Journal Of Cardiology 2017, 121: 343-348. PMID: 29268936, DOI: 10.1016/j.amjcard.2017.10.029.
Predictors of Death in Adults With Duchenne Muscular Dystrophy–Associated CardiomyopathyCheeran D, Khan S, Khera R, Bhatt A, Garg S, Grodin JL, Morlend R, Araj FG, Amin AA, Thibodeau JT, Das S, Drazner MH, Mammen PPA. Predictors of Death in Adults With Duchenne Muscular Dystrophy–Associated Cardiomyopathy Journal Of The American Heart Association 2017, 6: e006340. PMID: 29042427, PMCID: PMC5721845, DOI: 10.1161/jaha.117.006340.
Burden and Costs of “High Consumers” of Hospitalization-Related Care in Patients With Chronic Gastrointestinal and Liver Diseases in the United StatesNguyen N, Khera R, Ohno-Machado L, Sandborn W, Singh S. Burden and Costs of “High Consumers” of Hospitalization-Related Care in Patients With Chronic Gastrointestinal and Liver Diseases in the United States The American Journal Of Gastroenterology 2017, 112: s1501. DOI: 10.14309/00000434-201710001-02780.
Abstract 089: A Simple Algorithm Identifies Hypertensive Patients Who Benefit From Intensive Blood Pressure LoweringWang S, Khera R, Das S, Vigen R, Wang T, Luo X, Lu R, Zhan X, Xiao G, Vongpatanasin W, Xie Y. Abstract 089: A Simple Algorithm Identifies Hypertensive Patients Who Benefit From Intensive Blood Pressure Lowering Hypertension 2017, 70 DOI: 10.1161/hyp.70.suppl_1.089.
Comparison of Readmission Rates After Acute Myocardial Infarction in 3 Patient Age Groups (18 to 44, 45 to 64, and ≥65 Years) in the United StatesKhera R, Jain S, Pandey A, Agusala V, Kumbhani DJ, Das SR, Berry JD, de Lemos JA, Girotra S. Comparison of Readmission Rates After Acute Myocardial Infarction in 3 Patient Age Groups (18 to 44, 45 to 64, and ≥65 Years) in the United States The American Journal Of Cardiology 2017, 120: 1761-1767. PMID: 28865892, PMCID: PMC5825232, DOI: 10.1016/j.amjcard.2017.07.081.
With Great Power Comes Great ResponsibilityKhera R, Krumholz HM. With Great Power Comes Great Responsibility Circulation Cardiovascular Quality And Outcomes 2017, 10: e003846. PMID: 28705865, PMCID: PMC5728376, DOI: 10.1161/circoutcomes.117.003846.
Editorial Commentary: Deconstructing the dogma: Its time to untangle and reassess acute myocardial infarction careKhera R, Kumbhani DJ. Editorial Commentary: Deconstructing the dogma: Its time to untangle and reassess acute myocardial infarction care Trends In Cardiovascular Medicine 2017, 27: 492-493. PMID: 28760376, DOI: 10.1016/j.tcm.2017.06.010.
303 Biologic Therapy and Immunodulators are Associated with Decreased Risk of Cardiovascular Events in Patients with Immune-Mediated Inflammatory Diseases: A Systematic Review and Meta-AnalysisFumery M, Singh A, Khera R, Prokop L, Sandborn W, Curtis J, Singh S. 303 Biologic Therapy and Immunodulators are Associated with Decreased Risk of Cardiovascular Events in Patients with Immune-Mediated Inflammatory Diseases: A Systematic Review and Meta-Analysis Gastroenterology 2017, 152: s77. DOI: 10.1016/s0016-5085(17)30607-8.
Abstract P172: Exercise Hemodynamics of Heart Failure with Preserved Ejection Fraction: a Meta-AnalysisPark B, Khera R, Pandey A, Haykowsky M, Kitzman D, Berry J. Abstract P172: Exercise Hemodynamics of Heart Failure with Preserved Ejection Fraction: a Meta-Analysis Circulation 2017, 135 DOI: 10.1161/circ.135.suppl_1.p172.
BURDEN OF 30-DAY READMISSIONS IN ACUTE MYOCARDIAL INFARCTION AND HEART FAILURE IN THE UNITED STATES: A NATIONAL PERSPECTIVEKhera R, Girotra S, Pandey A, Jain S, Ayers C, Das S, Berry J, de Lemos J, Fonarow G. BURDEN OF 30-DAY READMISSIONS IN ACUTE MYOCARDIAL INFARCTION AND HEART FAILURE IN THE UNITED STATES: A NATIONAL PERSPECTIVE Journal Of The American College Of Cardiology 2017, 69: 222. DOI: 10.1016/s0735-1097(17)33611-2.
IMPLANTABLE CARDIOVERTER DEFIBRILLATORS FOR THE PREVENTION OF MORTALITY IN PATIENTS WITH NON-ISCHEMIC CARDIOMYOPATHY: A META-ANALYSIS OF RANDOMIZED CONTROL TRIALSOmar W, Parashar A, Khera R, Pandey A. IMPLANTABLE CARDIOVERTER DEFIBRILLATORS FOR THE PREVENTION OF MORTALITY IN PATIENTS WITH NON-ISCHEMIC CARDIOMYOPATHY: A META-ANALYSIS OF RANDOMIZED CONTROL TRIALS Journal Of The American College Of Cardiology 2017, 69: 904. DOI: 10.1016/s0735-1097(17)34293-6.
COMPARATIVE OUTCOMES OF TRANSCATHETER VERSUS SURGICAL AORTIC VALVE REPLACEMENT IN CHRONIC KIDNEY DISEASEKumar N, Khera R, Pandey A, Venkatraman A, Garg N. COMPARATIVE OUTCOMES OF TRANSCATHETER VERSUS SURGICAL AORTIC VALVE REPLACEMENT IN CHRONIC KIDNEY DISEASE Journal Of The American College Of Cardiology 2017, 69: 1217. DOI: 10.1016/s0735-1097(17)34606-5.
ROLE OF HOSPITAL VOLUME IN IDENTIFYING LOW AND HIGH-PERFORMING SURGICAL VALVE CENTERS IN THE UNITED STATESKhera R, Pandey A, Nallamothu B, Das S, Drazner M, Jessen M, Kirtane A, Bhatt D, de Lemos J, Kumbhani D. ROLE OF HOSPITAL VOLUME IN IDENTIFYING LOW AND HIGH-PERFORMING SURGICAL VALVE CENTERS IN THE UNITED STATES Journal Of The American College Of Cardiology 2017, 69: 1291. DOI: 10.1016/s0735-1097(17)34680-6.
P448 Biologic therapy and immunodulators are associated with decreased risk of cardiovascular events in patients with immune-mediated inflammatory diseases: a systematic review and meta-analysisFumery M, Singh A, Khera R, Prokop L, Curtis J, Sandborn W, Singh S. P448 Biologic therapy and immunodulators are associated with decreased risk of cardiovascular events in patients with immune-mediated inflammatory diseases: a systematic review and meta-analysis Journal Of Crohn's And Colitis 2017, 11: s305-s306. DOI: 10.1093/ecco-jcc/jjx002.573.
Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysisDulai PS, Singh S, Marquez E, Khera R, Prokop LJ, Limburg PJ, Gupta S, Murad MH. Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis The BMJ 2016, 355: i6188. PMID: 27919915, PMCID: PMC5137632, DOI: 10.1136/bmj.i6188.
Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac ArrestKhera R, Chan PS, Donnino M, Girotra S. Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest Circulation 2016, 134: 2105-2114. PMID: 27908910, PMCID: PMC5173427, DOI: 10.1161/circulationaha.116.025459.
Variation in Hospital Use and Outcomes Associated With Pulmonary Artery Catheterization in Heart Failure in the United StatesKhera R, Pandey A, Kumar N, Singh R, Bano S, Golwala H, Kumbhani DJ, Girotra S, Fonarow GC. Variation in Hospital Use and Outcomes Associated With Pulmonary Artery Catheterization in Heart Failure in the United States Circulation Heart Failure 2016, 9: e003226. PMID: 27780836, PMCID: PMC5123800, DOI: 10.1161/circheartfailure.116.003226.
356 Circulating EGF-Like Ligands in Obesity Increase Neointimal Formation through Upregulation of NADPH Oxidase 1Schickling B, Takapoo M, Khera R, Miller F. 356 Circulating EGF-Like Ligands in Obesity Increase Neointimal Formation through Upregulation of NADPH Oxidase 1 Free Radical Biology And Medicine 2016, 100: s151. DOI: 10.1016/j.freeradbiomed.2016.10.397.
Obesity Is Associated with Worse Outcomes in Hospitalized Patients with Inflammatory Bowel Diseases: A Nationwide AnalysisSingh S, Khera R, Sandborn W. Obesity Is Associated with Worse Outcomes in Hospitalized Patients with Inflammatory Bowel Diseases: A Nationwide Analysis The American Journal Of Gastroenterology 2016, 111: s271. DOI: 10.14309/00000434-201610001-00591.
Comparative Effectiveness of Pharmacologic Interventions for Pulmonary Arterial Hypertension A Systematic Review and Network Meta-AnalysisJain S, Khera R, Girotra S, Badesch D, Wang Z, Murad MH, Blevins A, Schmidt GA, Singh S, Gerke AK. Comparative Effectiveness of Pharmacologic Interventions for Pulmonary Arterial Hypertension A Systematic Review and Network Meta-Analysis CHEST Journal 2016, 151: 90-105. PMID: 27615023, PMCID: PMC5310124, DOI: 10.1016/j.chest.2016.08.1461.
Atrial fibrillation associated hospitalizations in patients with end-stage renal disease in the United States, 2003–2012Kumar N, Khera R, Garg N. Atrial fibrillation associated hospitalizations in patients with end-stage renal disease in the United States, 2003–2012 Heart Rhythm 2016, 13: 2027-2033. PMID: 27374238, DOI: 10.1016/j.hrthm.2016.06.031.
Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysisKhera R, Murad MH, Chandar AK, Dulai PS, Wang Z, Prokop LJ, Loomba R, Camilleri M, Singh S. Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis JAMA 2016, 315: 2424-2434. PMID: 27299618, PMCID: PMC5617638, DOI: 10.1001/jama.2016.7602.
Racial Differences in Outcomes after Acute Ischemic Stroke Hospitalization in the United StatesKumar N, Khera R, Pandey A, Garg N. Racial Differences in Outcomes after Acute Ischemic Stroke Hospitalization in the United States Journal Of Stroke And Cerebrovascular Diseases 2016, 25: 1970-1977. PMID: 27212273, DOI: 10.1016/j.jstrokecerebrovasdis.2016.03.049.
Response to “the Use of Mechanical Support Devices in Percutaneous Coronary Interventions: the Controversy?”Khera R, Girotra S. Response to “the Use of Mechanical Support Devices in Percutaneous Coronary Interventions: the Controversy?” The American Journal Of Cardiology 2016, 120: e5. PMID: 27269587, DOI: 10.1016/j.amjcard.2016.05.001.
Mechanical Circulatory Support and Rationale for Future Research—ReplyKhera R, Girotra S. Mechanical Circulatory Support and Rationale for Future Research—Reply JAMA Internal Medicine 2016, 176: 714-715. PMID: 27136338, DOI: 10.1001/jamainternmed.2016.0810.
Weekend hospitalizations for acute aortic dissection have a higher risk of in-hospital mortality compared to weekday hospitalizationsKumar N, Venkatraman A, Pandey A, Khera R, Garg N. Weekend hospitalizations for acute aortic dissection have a higher risk of in-hospital mortality compared to weekday hospitalizations International Journal Of Cardiology 2016, 214: 448-450. PMID: 27093682, DOI: 10.1016/j.ijcard.2016.03.187.
383 Comparative Efficacy and Tolerability of Long-Term Pharmacological Interventions for Obesity: A Systematic Review and Network Meta-AnalysisKhera R, Murad M, Chandar A, Dulai P, Wang Z, Prokop L, Loomba R, Camilleri M, Singh S. 383 Comparative Efficacy and Tolerability of Long-Term Pharmacological Interventions for Obesity: A Systematic Review and Network Meta-Analysis Gastroenterology 2016, 150: s87. DOI: 10.1016/s0016-5085(16)30408-5.
Su2048 Comparison of Pharmacologic Agents for Chemoprevention of Colorectal Cancer in At-Risk Individuals - A Systematic Review and Network Meta-AnalysisDulai P, Marquez E, Khera R, Prokop L, Gupta S, Limburg P, Murad M, Singh S. Su2048 Comparison of Pharmacologic Agents for Chemoprevention of Colorectal Cancer in At-Risk Individuals - A Systematic Review and Network Meta-Analysis Gastroenterology 2016, 150: s620-s621. DOI: 10.1016/s0016-5085(16)32130-8.
REGIONAL DIFFERENCES IN OUTCOMES OF HEART FAILURE HOSPITALIZATION IN THE UNITED STATES: A CONTEMPORARY NATIONWIDE ANALYSISKumar N, Mehta A, Khera R, Garg N, Pandey A. REGIONAL DIFFERENCES IN OUTCOMES OF HEART FAILURE HOSPITALIZATION IN THE UNITED STATES: A CONTEMPORARY NATIONWIDE ANALYSIS Journal Of The American College Of Cardiology 2016, 67: 1300. DOI: 10.1016/s0735-1097(16)31301-8.
Response to “Higher mortality among males in takotsubo cardiomyopathy”Khera R, Girotra S. Response to “Higher mortality among males in takotsubo cardiomyopathy” American Heart Journal 2016, 176: e3. PMID: 27264234, DOI: 10.1016/j.ahj.2016.03.010.
Abstract 165: Hospital Variation in Time to Administration of Epinephrine After Cardiac Arrest With Initial Non-shockable RhythmKhera R, Chan P, Donnino M, Girotra S. Abstract 165: Hospital Variation in Time to Administration of Epinephrine After Cardiac Arrest With Initial Non-shockable Rhythm Circulation Cardiovascular Quality And Outcomes 2016, 9 DOI: 10.1161/circoutcomes.9.suppl_2.165.
ReplySingh S, Khera R, Murad MH, Loomba R. Reply Hepatology 2016, 64: 694-694. PMID: 26690078, DOI: 10.1002/hep.28412.
Use of Pulmonary Artery Catheterization in US Patients With Heart Failure, 2001-2012Pandey A, Khera R, Kumar N, Golwala H, Girotra S, Fonarow GC. Use of Pulmonary Artery Catheterization in US Patients With Heart Failure, 2001-2012 JAMA Internal Medicine 2016, 176: 1-4. PMID: 26618346, PMCID: PMC4780342, DOI: 10.1001/jamainternmed.2015.6190.
Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary EmbolismJain S, Khera R, Suneja M, Gehlbach B, Kuperman E, Lopez F. Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism The American Journal Of The Medical Sciences 2015, 350: 501-507. PMID: 25719981, DOI: 10.1097/maj.0000000000000405.
Trends in hospitalization for takotsubo cardiomyopathy in the United StatesKhera R, Light-McGroary K, Zahr F, Horwitz PA, Girotra S. Trends in hospitalization for takotsubo cardiomyopathy in the United States American Heart Journal 2015, 172: 53-63. PMID: 26856216, PMCID: PMC4748175, DOI: 10.1016/j.ahj.2015.10.022.
Abstract 12358: Epidemiology of Acute Myocardial infarction in Systemic Sclerosis: Incidence and OutcomesKhera R, Jain S, Kumar N, Singh N, Derk C, Girotra S. Abstract 12358: Epidemiology of Acute Myocardial infarction in Systemic Sclerosis: Incidence and Outcomes Circulation 2015, 132 DOI: 10.1161/circ.132.suppl_3.12358.
Abstract 15447: Trends in Use of Pulmonary Artery Catheterization in Heart Failure in the United States, 2006 - 2012Khera R, Pandey A, Kumar N, Girotra S, Fonarow G. Abstract 15447: Trends in Use of Pulmonary Artery Catheterization in Heart Failure in the United States, 2006 - 2012 Circulation 2015, 132 DOI: 10.1161/circ.132.suppl_3.15447.
Abstract 18891: Racial Differences in End-of-life Care Associated With Heart Failure Hospitalizations in the United States: A Population-based Analysis From 2011-2012Kumar N, Khera R, Garg N. Abstract 18891: Racial Differences in End-of-life Care Associated With Heart Failure Hospitalizations in the United States: A Population-based Analysis From 2011-2012 Circulation 2015, 132 DOI: 10.1161/circ.132.suppl_3.18891.
Abstract 19212: Racial Differences in Clinical Outcomes and Resource Utilization Associated With Heart Failure Hospitalizations in the United States: A Nationwide Analysis From 2011-2012Kumar N, Khera R, Garg N. Abstract 19212: Racial Differences in Clinical Outcomes and Resource Utilization Associated With Heart Failure Hospitalizations in the United States: A Nationwide Analysis From 2011-2012 Circulation 2015, 132 DOI: 10.1161/circ.132.suppl_3.19212.
Abstract 19569: Racial Differences in Clinical Outcomes and Resource Utilization Associated With Acute Myocardial Infarction Hospitalizations in the United States: A Population-wide Analysis From 2011-2012Kumar N, Khera R, Garg N. Abstract 19569: Racial Differences in Clinical Outcomes and Resource Utilization Associated With Acute Myocardial Infarction Hospitalizations in the United States: A Population-wide Analysis From 2011-2012 Circulation 2015, 132 DOI: 10.1161/circ.132.suppl_3.19569.
Use of Mechanical Circulatory Support in Percutaneous Coronary Intervention in the United StatesKhera R, Cram P, Vaughan-Sarrazin M, Horwitz PA, Girotra S. Use of Mechanical Circulatory Support in Percutaneous Coronary Intervention in the United States The American Journal Of Cardiology 2015, 117: 10-16. PMID: 26547292, PMCID: PMC4690753, DOI: 10.1016/j.amjcard.2015.10.005.
Pacemaker Dependency after Cardiac Surgery: A Systematic Review of Current EvidenceSteyers CM, Khera R, Bhave P. Pacemaker Dependency after Cardiac Surgery: A Systematic Review of Current Evidence PLOS ONE 2015, 10: e0140340. PMID: 26470027, PMCID: PMC4607414, DOI: 10.1371/journal.pone.0140340.
Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta‐analysisSingh S, Khera R, Allen AM, Murad MH, Loomba R. Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta‐analysis Hepatology 2015, 62: 1417-1432. PMID: 26189925, DOI: 10.1002/hep.27999.
Herpes zoster ophthalmicus complicated by encephalitisJain S, Khera R. Herpes zoster ophthalmicus complicated by encephalitis Canadian Medical Association Journal 2015, 188: cmaj.150342. PMID: 26350907, PMCID: PMC4771550, DOI: 10.1503/cmaj.150342.
Letter by Khera et al Regarding Article, “Impact of Annual Operator and Institutional Volume on Percutaneous Coronary Intervention OutcomesKhera R, Cram P, Girotra S. Letter by Khera et al Regarding Article, “Impact of Annual Operator and Institutional Volume on Percutaneous Coronary Intervention Outcomes Circulation 2015, 132: e35. PMID: 26240269, PMCID: PMC4617823, DOI: 10.1161/circulationaha.114.013342.
Distinct interneuronal networks influence excitability of the surround during movement initiationThirugnanasambandam N, Khera R, Wang H, Kukke SN, Hallett M. Distinct interneuronal networks influence excitability of the surround during movement initiation Journal Of Neurophysiology 2015, 114: 1102-1108. PMID: 26041828, PMCID: PMC4588516, DOI: 10.1152/jn.00791.2014.
Trends in the Use of Percutaneous Ventricular Assist Devices: Analysis of National Inpatient Sample Data, 2007 Through 2012Khera R, Cram P, Lu X, Vyas A, Gerke A, Rosenthal GE, Horwitz PA, Girotra S. Trends in the Use of Percutaneous Ventricular Assist Devices: Analysis of National Inpatient Sample Data, 2007 Through 2012 JAMA Internal Medicine 2015, 175: 941-950. PMID: 25822170, PMCID: PMC4780323, DOI: 10.1001/jamainternmed.2014.7856.
Abstract 114: Mechanical Circulatory Support in Percutaneous Coronary Intervention: A Propensity-matched AnalysisKhera R, Cram P, Vaughan-Sarrazin M, Horwitz P, Girotra S. Abstract 114: Mechanical Circulatory Support in Percutaneous Coronary Intervention: A Propensity-matched Analysis Circulation Cardiovascular Quality And Outcomes 2015, 8 DOI: 10.1161/circoutcomes.8.suppl_2.114.
Racial Disparities in Outcomes After Cardiac Surgery: the Role of Hospital QualityKhera R, Vaughan-Sarrazin M, Rosenthal GE, Girotra S. Racial Disparities in Outcomes After Cardiac Surgery: the Role of Hospital Quality Current Cardiology Reports 2015, 17: 29. PMID: 25894800, PMCID: PMC4780328, DOI: 10.1007/s11886-015-0587-7.
Su1040 Comparative Effectiveness of Pharmacologic Treatments for Non-Alcoholic Steatohepatitis: A Systematic Review and Network Meta-AnalysisSingh S, Khera R, Allen A, Bongiorno C, Murad M, Loomba R. Su1040 Comparative Effectiveness of Pharmacologic Treatments for Non-Alcoholic Steatohepatitis: A Systematic Review and Network Meta-Analysis Gastroenterology 2015, 148: s-1046-s-1047. DOI: 10.1016/s0016-5085(15)33570-8.
TRENDS IN HOSPITALIZATION FOR TAKOTSUBO CARDIOMYOPATHY IN THE UNITED STATES, 2007-2012Khera R, Vyas A, Light-McGroary K, Zahr F, Horwitz P, Girotra S. TRENDS IN HOSPITALIZATION FOR TAKOTSUBO CARDIOMYOPATHY IN THE UNITED STATES, 2007-2012 Journal Of The American College Of Cardiology 2015, 65: a921. DOI: 10.1016/s0735-1097(15)60921-4.
DIFFERENCES IN PATIENT CHARACTERISTICS AND IN-HOSPITAL MORTALITY WITH THE USE OF INTRA-AORTIC BALLOON PUMP VERSUS PERCUTANEOUS VENTRICULAR ASSIST DEVICES IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTIONKhera R, Horwitz P, Girotra S. DIFFERENCES IN PATIENT CHARACTERISTICS AND IN-HOSPITAL MORTALITY WITH THE USE OF INTRA-AORTIC BALLOON PUMP VERSUS PERCUTANEOUS VENTRICULAR ASSIST DEVICES IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION Journal Of The American College Of Cardiology 2015, 65: a1754. DOI: 10.1016/s0735-1097(15)61754-5.
“Inflammation and arterial stiffness in humans”Jain S, Khera R, Corrales–Medina V, Townsend RR, Chirinos JA. “Inflammation and arterial stiffness in humans” Atherosclerosis 2014, 237: 381-390. PMID: 25463062, DOI: 10.1016/j.atherosclerosis.2014.09.011.
Gender bias in child care and child health: global patternsKhera R, Jain S, Lodha R, Ramakrishnan S. Gender bias in child care and child health: global patterns Archives Of Disease In Childhood 2013, 99: 369. PMID: 24344176, DOI: 10.1136/archdischild-2013-303889.
P 14. A detailed evaluation of surround inhibition in human motor cortex using transcranial magnetic stimulationThirugnanasambandam N, Khera R, Wang H, Kukke S, Hallett M. P 14. A detailed evaluation of surround inhibition in human motor cortex using transcranial magnetic stimulation Clinical Neurophysiology 2013, 124: e71. DOI: 10.1016/j.clinph.2013.04.093.
Membrane-Bound Complement Regulatory Proteins as Biomarkers and Potential Therapeutic Targets for SLEDas N, Biswas B, Khera R. Membrane-Bound Complement Regulatory Proteins as Biomarkers and Potential Therapeutic Targets for SLE 2012, 735: 55-81. PMID: 23402019, DOI: 10.1007/978-1-4614-4118-2_4.
Gender differences in the utilisation of surgery for congenital heart disease in IndiaRamakrishnan S, Khera R, Jain S, Saxena A, Kailash S, Karthikeyan G, Kothari SS, Juneja R, Bhargava B, Kalaivani M, Mehta M, Bahl VK, Airan B. Gender differences in the utilisation of surgery for congenital heart disease in India Heart 2011, 97: 1920. PMID: 21653217, DOI: 10.1136/hrt.2011.224410.
Diffuse large B-cell lymphoma: experience from a tertiary care center in north IndiaKhera R, Jain S, Kumar L, Thulkar S, Vijayraghwan M, Dawar R. Diffuse large B-cell lymphoma: experience from a tertiary care center in north India Medical Oncology 2009, 27: 310-318. PMID: 19350421, DOI: 10.1007/s12032-009-9211-2.
F.12. Relationship of Complement Receptor 1 Density Polymorphism at Intron 27 (HindIII RFLP) to Plasmodium falciparum Malaria and its Severity in an Indian ScenarioKhera R, Madhukar M, Aggarwal P, Samantaray J, Biswas S, Das N. F.12. Relationship of Complement Receptor 1 Density Polymorphism at Intron 27 (HindIII RFLP) to Plasmodium falciparum Malaria and its Severity in an Indian Scenario Clinical Immunology 2009, 131: s96. DOI: 10.1016/j.clim.2009.03.280.
Complement Receptor 1: Disease associations and therapeutic implicationsKhera R, Das N. Complement Receptor 1: Disease associations and therapeutic implications Molecular Immunology 2008, 46: 761-772. PMID: 19004497, PMCID: PMC7125513, DOI: 10.1016/j.molimm.2008.09.026.

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