Mark David Siegel, MD

• Alexander B. Pine
• Alfred Lee
• Ami Rubinowitz
• Amy Schwartz
• Andrey Zinchuk
• Benjamin Tolchin
• Bishwajit Bhattacharya
• Christopher G Bunick
• Danish Zaidi
• Gary Désir
• Jacqueline Geer
• Jennifer Kapo
• Jennifer Possick
• Jonathan Siner
• Kathleen Cook Suozzi
• Kevin Schuster
• Kimberly Davis
• Lauren Ferrante
• Lynn Acton
• Maor Sauler
• Margaret Pisani
• Sarah C. Hull
• Scott Gettinger
• Shyoko Honiden
• Stephen Wang
• Terence Trow
• Theodore Long

Chronic Disease; Education, Medical, Graduate; Ethics, Medical; Respiratory Distress Syndrome; Terminal Care; Pulmonary Medicine; Sepsis

• Imaging in the Intensive Care UnitToy D, Siegel M, Rubinowitz A. Imaging in the Intensive Care Unit Seminars In Respiratory And Critical Care Medicine 2022, 43: 899-923. PMID: 36442475, DOI: 10.1055/s-0042-1750041.
• Reflections on New Evidence on Crisis Standards of Care in the COVID-19 Pandemic.Tolchin B, Latham SR, Bruce L, Ferrante LE, Kraschel K, Jubanyik K, Hull SC, Herbst JL, Kapo J, Moritz ED, Hughes J, Siegel MD, Mercurio MR. Reflections on New Evidence on Crisis Standards of Care in the COVID-19 Pandemic. The Journal Of Clinical Ethics 2021, 32: 358-360. PMID: 34928864, DOI: 10.1086/jce2021324358.
• The Other Side of Triage: When Access to Intensive Care Measures May Do More Harm than GoodFeder KJ, Zaidi D, Siegel MD. The Other Side of Triage: When Access to Intensive Care Measures May Do More Harm than Good The American Journal Of Bioethics 2021, 21: 79-82. PMID: 34710018, DOI: 10.1080/15265161.2021.1980136.
• Challenges in interpreting cytokine data in COVID-19 affect patient care and managementWang SY, Takahashi T, Pine AB, Damsky WE, Simonov M, Zhang Y, Kieras E, Price CC, King BA, Siegel MD, Desir GV, Lee AI, Iwasaki A, Chun HJ. Challenges in interpreting cytokine data in COVID-19 affect patient care and management PLOS Biology 2021, 19: e3001373. PMID: 34358229, PMCID: PMC8372945, DOI: 10.1371/journal.pbio.3001373.
• Developing a Triage Protocol for the COVID-19 Pandemic: Allocating Scarce Medical Resources in a Public Health Emergency.Tolchin B, Latham SR, Bruce L, Ferrante LE, Kraschel K, Jubanyik K, Hull SC, Herbst JL, Kapo J, Moritz ED, Hughes J, Siegel MD, Mercurio MR. Developing a Triage Protocol for the COVID-19 Pandemic: Allocating Scarce Medical Resources in a Public Health Emergency. The Journal Of Clinical Ethics 2020, 31: 303-317. PMID: 32991327, DOI: 10.1086/jce2020314303.
• Making Medical Treatment Decisions for Unrepresented Patients in the ICU. An Official American Thoracic Society/American Geriatrics Society Policy StatementPope TM, Bennett J, Carson SS, Cederquist L, Cohen AB, DeMartino ES, Godfrey DM, Goodman-Crews P, Kapp MB, Lo B, Magnus DC, Reinke LF, Shirley JL, Siegel MD, Stapleton RD, Sudore RL, Tarzian AJ, Thornton JD, Wicclair MR, Widera EW, White DB. Making Medical Treatment Decisions for Unrepresented Patients in the ICU. An Official American Thoracic Society/American Geriatrics Society Policy Statement American Journal Of Respiratory And Critical Care Medicine 2020, 201: 1182-1192. PMID: 32412853, PMCID: PMC7233335, DOI: 10.1164/rccm.202003-0512st.
• A novel approach to the program evaluation committeeSchwartz AR, Siegel MD, Lee AI. A novel approach to the program evaluation committee BMC Medical Education 2019, 19: 465. PMID: 31842868, PMCID: PMC6916454, DOI: 10.1186/s12909-019-1899-x.
• Antibiotics and the Yield of Blood Cultures: Sequence Matters.Geer JH, Siegel MD. Antibiotics and the Yield of Blood Cultures: Sequence Matters. Annals Of Internal Medicine 2019, 171: 587-588. PMID: 31525773, DOI: 10.7326/m19-2489.
• The Unintended Consequences of Hope.Siegel MD. The Unintended Consequences of Hope. Critical Care Medicine 2019, 47: 1267-1268. PMID: 31415310, DOI: 10.1097/CCM.0000000000003878.
• Evaluation of Swallow Function Post-Extubation: Is It Necessary to Wait 24 Hours?Leder SB, Warner HL, Suiter DM, Young NO, Bhattacharya B, Siner JM, Davis KA, Maerz LL, Rosenbaum SH, Marshall PS, Pisani MA, Siegel MD, Brennan JJ, Schuster KM. Evaluation of Swallow Function Post-Extubation: Is It Necessary to Wait 24 Hours? Annals Of Otology Rhinology & Laryngology 2019, 128: 619-624. PMID: 30841709, DOI: 10.1177/0003489419836115.
• Internal medicine trainees' knowledge and confidence in using the American Society of Hematology Choosing Wisely guidelines in hemostasis, thrombosis, and non-malignant hematologyMarshall AL, Jenkins S, Oxentenko AS, Lee AI, Siegel MD, Katz JT, Vyas JM, Del Valle J, Mikhael JR. Internal medicine trainees' knowledge and confidence in using the American Society of Hematology Choosing Wisely guidelines in hemostasis, thrombosis, and non-malignant hematology PLOS ONE 2018, 13: e0197414. PMID: 29768480, PMCID: PMC5955511, DOI: 10.1371/journal.pone.0197414.
• A Young Man With Hemoptysis and Cavitary Lung LesionsBrady VA, Zinchuk AV, Siegel MD, Possick JD. A Young Man With Hemoptysis and Cavitary Lung Lesions CHEST Journal 2018, 153: e85-e88. PMID: 29626974, PMCID: PMC6026285, DOI: 10.1016/j.chest.2017.09.018.
• A Sudden Loss Of Vision.Siegel MD. A Sudden Loss Of Vision. Journal Of The American Geriatrics Society 2017, 65: 1882. PMID: 28555719, DOI: 10.1111/jgs.14946.
• Not “Out of Sight, Out of Mind”Bournival N, Siegel MD, Akgün KM. Not “Out of Sight, Out of Mind” Critical Care Medicine 2017, 45: 134-136. PMID: 27984282, DOI: 10.1097/ccm.0000000000002119.
• Immune-related sarcoidosis observed in combination ipilimumab and nivolumab therapySuozzi KC, Stahl M, Ko CJ, Chiang A, Gettinger SN, Siegel MD, Bunick CG. Immune-related sarcoidosis observed in combination ipilimumab and nivolumab therapy JAAD Case Reports 2016, 2: 264-268. PMID: 27486590, PMCID: PMC4949498, DOI: 10.1016/j.jdcr.2016.05.002.
• Critical Care at the End of LifeAkgün KM, Kapo JM, Siegel MD. Critical Care at the End of Life Seminars In Respiratory And Critical Care Medicine 2015, 36: 921-933. PMID: 26600274, DOI: 10.1055/s-0035-1565254.
• Use of the Blom Tracheotomy Tube with Suction Inner Cannula to Decontaminate Microorganisms from the Subglottic Space. A Proof of ConceptRabach L, Siegel MD, Puchalski JT, Towle D, Follert M, Johnson KM, Rademaker AW, Leder SB. Use of the Blom Tracheotomy Tube with Suction Inner Cannula to Decontaminate Microorganisms from the Subglottic Space. A Proof of Concept Annals Of The American Thoracic Society 2015, 12: 859-863. PMID: 25849332, DOI: 10.1513/annalsats.201501-010bc.
• Bringing Specialties Together: The Power of Intra-Professional TeamsBongiovanni T, Long T, Khan AM, Siegel MD. Bringing Specialties Together: The Power of Intra-Professional Teams Journal Of Graduate Medical Education 2015, 7: 19-20. PMID: 26217416, PMCID: PMC4507920, DOI: 10.4300/jgme-d-14-00509.1.
• Guiding the guiders. Recognizing surrogates' needs and advancing communication in the intensive care unit.Netzer G, Siegel MD. Guiding the guiders. Recognizing surrogates' needs and advancing communication in the intensive care unit. Annals Of The American Thoracic Society 2015, 12: 237-8. PMID: 25706488, DOI: 10.1513/AnnalsATS.201501-028ED.
• An Official American Thoracic Society Policy Statement: Managing Conscientious Objections in Intensive Care MedicineLewis-Newby M, Wicclair M, Pope T, Rushton C, Curlin F, Diekema D, Durrer D, Ehlenbach W, Gibson-Scipio W, Glavan B, Langer L, Manthous C, Rose C, Scardella A, Shanawani H, Siegel MD, Halpern SD, Truog RD, White DB. An Official American Thoracic Society Policy Statement: Managing Conscientious Objections in Intensive Care Medicine American Journal Of Respiratory And Critical Care Medicine 2015, 191: 219-227. PMID: 25590155, DOI: 10.1164/rccm.201410-1916st.
• Unresolved pulmonary embolism leading to a diagnosis of pulmonary artery sarcomaGutiérrez A, Sauler M, Mitchell JM, Siegel MD, Trow TK, Bacchetta M, Fares WH. Unresolved pulmonary embolism leading to a diagnosis of pulmonary artery sarcoma Heart & Lung 2014, 43: 574-576. PMID: 24928184, DOI: 10.1016/j.hrtlng.2014.05.006.
• Recurrent Hydrothorax and Surgical Diaphragmatic RepairArgento A, Kim A, Knauert-Brown M, Boffa D, Siegel MD, Jafari B, Puchalski JT. Recurrent Hydrothorax and Surgical Diaphragmatic Repair Journal Of Bronchology & Interventional Pulmonology 2014, 21: 150-153. PMID: 24739690, DOI: 10.1097/lbr.0000000000000047.
• Penguins and Palliative CareKapo J, Siegel MD. Penguins and Palliative Care Critical Care Medicine 2013, 41: 2443-2444. PMID: 24060776, DOI: 10.1097/ccm.0b013e31829136f3.
• Ethical Considerations in Embedding a Surgeon in a Military or Civilian Tactical TeamKaplan LJ, Siegel MD, Eastman AL, Flynn LM, Rosenbaum SH, Cone DC, Blake DP, Mulhern J. Ethical Considerations in Embedding a Surgeon in a Military or Civilian Tactical Team Prehospital And Disaster Medicine 2012, 27: 583-588. PMID: 22985714, DOI: 10.1017/s1049023x12001112.
• Pathogenetic and predictive value of biomarkers in patients with ALI and lower severity of illness: results from two clinical trialsAgrawal A, Zhuo H, Brady S, Levitt J, Steingrub J, Siegel MD, Soto G, Peterson MW, Chesnutt MS, Matthay MA, Liu KD. Pathogenetic and predictive value of biomarkers in patients with ALI and lower severity of illness: results from two clinical trials American Journal Of Physiology - Lung Cellular And Molecular Physiology 2012, 303: l634-l639. PMID: 22865551, PMCID: PMC3469636, DOI: 10.1152/ajplung.00195.2012.
• The ethical and economic impact of defaults.Siegel MD, Stapleton R, Wunsch H. The ethical and economic impact of defaults. Seminars In Respiratory And Critical Care Medicine 2012, 33: 382-92. PMID: 22875385, DOI: 10.1055/s-0032-1322402.
• Using standardized family members to teach end-of-life skills to critical care trainees*Akgün KM, Siegel MD. Using standardized family members to teach end-of-life skills to critical care trainees* Critical Care Medicine 2012, 40: 1978-1980. PMID: 22610211, DOI: 10.1097/ccm.0b013e3182536cd1.
• Adapting To the New Consensus Guidelines for Managing Hyperglycemia During Critical Illness: the Updated Yale Insulin Infusion ProtocolShetty S, Inzucchi SE, Goldberg PA, Cooper D, Siegel MD, Honiden S. Adapting To the New Consensus Guidelines for Managing Hyperglycemia During Critical Illness: the Updated Yale Insulin Infusion Protocol Endocrine Practice 2012, 18: 363-370. PMID: 22138078, DOI: 10.4158/ep11260.or.
• Within the black boxSiegel MD, Perez MT. Within the black box Critical Care Medicine 2012, 40: 1339-1340. PMID: 22425829, DOI: 10.1097/ccm.0b013e3182451b76.
• Palliative Care in the ICUNelson M, Azoulay P, Curtis JR, Mosenthal AC, Mulkerin CM, Puntillo K, Siegel MD. Palliative Care in the ICU Journal Of Palliative Medicine 2012, 15: 168-174. PMID: 22280492, PMCID: PMC3388494, DOI: 10.1089/jpm.2011.9599.
• Stranger in a strange landAkgün KM, Siegel MD. Stranger in a strange land Critical Care Medicine 2012, 40: 312-313. PMID: 22179354, DOI: 10.1097/ccm.0b013e3182326694.
• The Past, Present, and Future of Advance Directives as a Guide to End-of-Life Decision MakingSauler M, Siegel MD. The Past, Present, and Future of Advance Directives as a Guide to End-of-Life Decision Making CHEST Journal 2012, 141: 9-10. PMID: 22215824, DOI: 10.1378/chest.11-2744.
• Safe initiation of oral diets in hospitalized patients based on passing a 3-ounce (90 cc) water swallow challenge protocolLeder SB, Suiter DM, Warner HL, Acton LM, Siegel MD. Safe initiation of oral diets in hospitalized patients based on passing a 3-ounce (90 cc) water swallow challenge protocol QJM 2011, 105: 257-263. PMID: 22006561, DOI: 10.1093/qjmed/hcr193.
• The Management of the Critically Ill Obstetric PatientHoniden S, Abdel-Razeq SS, Siegel MD. The Management of the Critically Ill Obstetric Patient Journal Of Intensive Care Medicine 2011, 28: 93-106. PMID: 21841145, DOI: 10.1177/0885066611411408.
• Success Stories: Use of Patient Vignettes to Assess the Ability of Physicians to Predict Extubation SuccessSiner JM, Siegel MD. Success Stories: Use of Patient Vignettes to Assess the Ability of Physicians to Predict Extubation Success Respiratory Care 2011, 56: 1050-1051. PMID: 21740729, DOI: 10.4187/respcare.01438.
• Diagnosis and Management of Life-Threatening Pulmonary EmbolismMarshall PS, Mathews KS, Siegel MD. Diagnosis and Management of Life-Threatening Pulmonary Embolism Journal Of Intensive Care Medicine 2011, 26: 275-294. PMID: 21606060, DOI: 10.1177/0885066610392658.
• Self-efficacy approaches to improving end-of-life care for the critically ill: ineffective, insufficient, or inconclusive?Azoulay E, Siegel MD. Self-efficacy approaches to improving end-of-life care for the critically ill: ineffective, insufficient, or inconclusive? American Journal Of Respiratory And Critical Care Medicine 2011, 183: 288-90. PMID: 21288861, DOI: 10.1164/rccm.201010-1759ED.
• Hypothermia and protection from acetaminophen-induced liver injury.Marotta SE, Belchikov Y, Siegel MD. Hypothermia and protection from acetaminophen-induced liver injury. Therapeutic Hypothermia And Temperature Management 2011, 1: 57-60. PMID: 24716888, DOI: 10.1089/ther.2010.0005.
• Analytic Reviews: Managing the Agitated Patient in the ICU: Sedation, Analgesia, and Neuromuscular BlockadeHoniden S, Siegel MD. Analytic Reviews: Managing the Agitated Patient in the ICU: Sedation, Analgesia, and Neuromuscular Blockade Journal Of Intensive Care Medicine 2010, 25: 187-204. PMID: 20663774, DOI: 10.1177/0885066610366923.
• The Perception Gap Race, Religion, and Prognosis in the ICUSiegel MD, Prigerson HG. The Perception Gap Race, Religion, and Prognosis in the ICU CHEST Journal 2010, 138: 8-9. PMID: 20605808, DOI: 10.1378/chest.10-0454.
• Do you see what I see? Families, physicians, and prognostic dissonance in the intensive care unit.Siegel MD. Do you see what I see? Families, physicians, and prognostic dissonance in the intensive care unit. Critical Care Medicine 2010, 38: 1381-2. PMID: 20404633, DOI: 10.1097/CCM.0b013e3181da4652.
• Analytic review: management of life-threatening asthma in adults.Mannam P, Siegel MD. Analytic review: management of life-threatening asthma in adults. Journal Of Intensive Care Medicine 2010, 25: 3-15. PMID: 20085924, DOI: 10.1177/0885066609350866.
• Routine daily vs on-demand chest radiographs in intensive careSiegel MD, Rubinowitz AN. Routine daily vs on-demand chest radiographs in intensive care The Lancet 2009, 374: 1656-1658. PMID: 19896185, DOI: 10.1016/s0140-6736(09)61632-9.
• ELEVATED SERUM ANGIOPOIETIN 2 LEVELS ARE ASSOCIATED WITH INCREASED MORTALITY IN SEPSISSiner JM, Bhandari V, Engle KM, Elias JA, Siegel MD. ELEVATED SERUM ANGIOPOIETIN 2 LEVELS ARE ASSOCIATED WITH INCREASED MORTALITY IN SEPSIS Shock 2009, 31: 348-353. PMID: 18791490, DOI: 10.1097/shk.0b013e318188bd06.
• Glucose Control in the ICU — How Tight Is Too Tight?Inzucchi SE, Siegel MD. Glucose Control in the ICU — How Tight Is Too Tight? New England Journal Of Medicine 2009, 360: 1346-1349. PMID: 19318385, DOI: 10.1056/nejme0901507.