Laura Ment, MD
Research & Publications
Biography
News
Research Summary
Laura R. Ment, M.D., studies the impact of injury and recovering on developing brain in preterm neonates, fetuses with congenital heart disease and fetuses and neonates at risk for autism spectrum disorder. Dr. Ment and her colleagues employ serial neurodevelopmental outcome measures coupled with volumetric, functional and diffusion tensor imaging strategies to assess the influence of these perturbations on neural connectivity and the relationship of connectivity to outcome.
Specialized Terms: Adaptive Mechanisms of Developing Brain; Clinical Studies of Pathophysiology and Gene Targets for Prevention of Injury to Preterm Brain; Volumetric, Diffusion Tensor and Functional Imaging of Developmental Changes; Preclinical Studies in employing Animal Models of Injury and Repair in Preterm Brain with MRI, Genetic and Behavioral Assessments
Coauthors
Research Interests
Brain; Magnetic Resonance Imaging; Neurology; Pediatrics; Diffusion Tensor Imaging; Functional Neuroimaging
Research Image
Comparison of preterm (PT) - and term (T) -born fetuses using voxel-level connectivity
Selected Publications
- Hypoconnectivity between anterior insula and amygdala associates with future vulnerabilities in social development in a neurodiverse sample of neonatesScheinost D, Chang J, Lacadie C, Brennan-Wydra E, Foster R, Boxberger A, Macari S, Vernetti A, Constable RT, Ment LR, Chawarska K. Hypoconnectivity between anterior insula and amygdala associates with future vulnerabilities in social development in a neurodiverse sample of neonates Scientific Reports 2022, 12: 16230. PMID: 36171268, PMCID: PMC9517994, DOI: 10.1038/s41598-022-20617-6.
- Brain injury patterns in hypoxic ischemic encephalopathy of term neonatesBobba PS, Malhotra A, Sheth KN, Taylor SN, Ment LR, Payabvash S. Brain injury patterns in hypoxic ischemic encephalopathy of term neonates Journal Of Neuroimaging 2022, 33: 79-84. PMID: 36164277, DOI: 10.1111/jon.13052.
- Age-dependent white matter microstructural disintegrity in autism spectrum disorderWeber CF, Lake EMR, Haider SP, Mozayan A, Mukherjee P, Scheinost D, Bamford NS, Ment L, Constable T, Payabvash S. Age-dependent white matter microstructural disintegrity in autism spectrum disorder Frontiers In Neuroscience 2022, 16: 957018. PMID: 36161157, PMCID: PMC9490315, DOI: 10.3389/fnins.2022.957018.
- Continuous EEG monitoring still recommended for neonatal seizure management: commentary on NEST trialSoul JS, Glass HC, Mohammad K, Ment LR, Smyser CD, Bonifacio SL, Massaro AN, El-Dib M. Continuous EEG monitoring still recommended for neonatal seizure management: commentary on NEST trial Pediatric Research 2022, 93: 469-470. PMID: 35681096, DOI: 10.1038/s41390-022-02138-0.
- Age‐related topographic map of magnetic resonance diffusion metrics in neonatal brainsBobba PS, Weber CF, Mak A, Mozayan A, Malhotra A, Sheth KN, Taylor SN, Vossough A, Grant PE, Scheinost D, Constable RT, Ment LR, Payabvash S. Age‐related topographic map of magnetic resonance diffusion metrics in neonatal brains Human Brain Mapping 2022, 43: 4326-4334. PMID: 35599634, PMCID: PMC9435001, DOI: 10.1002/hbm.25956.
- Functional connectivity for the language network in the developing brain: 30 weeks of gestation to 30 months of ageScheinost D, Chang J, Lacadie C, Brennan-Wydra E, Constable RT, Chawarska K, Ment LR. Functional connectivity for the language network in the developing brain: 30 weeks of gestation to 30 months of age Cerebral Cortex 2021, 32: 3289-3301. PMID: 34875024, PMCID: PMC9340393, DOI: 10.1093/cercor/bhab415.
- ReplyInder TE, de Vries LS, Ment LR. Reply The Journal Of Pediatrics 2021, 239: 248-249. PMID: 34390695, DOI: 10.1016/j.jpeds.2021.08.007.
- Neuroimaging of the Preterm Brain: Review and RecommendationsInder TE, de Vries LS, Ferriero DM, Grant PE, Ment LR, Miller SP, Volpe JJ. Neuroimaging of the Preterm Brain: Review and Recommendations The Journal Of Pediatrics 2021, 237: 276-287.e4. PMID: 34146549, DOI: 10.1016/j.jpeds.2021.06.014.
- Food Insecurity in Medical Students: Preliminary Data From Yale School of Medicine.Zhou AG, Mercier MR, Chan C, Criscione J, Angoff N, Ment LR. Food Insecurity in Medical Students: Preliminary Data From Yale School of Medicine. Academic Medicine 2021, 96: 774-776. PMID: 34031298, DOI: 10.1097/acm.0000000000004048.
- Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalusJin SC, Dong W, Kundishora AJ, Panchagnula S, Moreno-De-Luca A, Furey CG, Allocco AA, Walker RL, Nelson-Williams C, Smith H, Dunbar A, Conine S, Lu Q, Zeng X, Sierant MC, Knight JR, Sullivan W, Duy PQ, DeSpenza T, Reeves BC, Karimy JK, Marlier A, Castaldi C, Tikhonova IR, Li B, Peña HP, Broach JR, Kabachelor EM, Ssenyonga P, Hehnly C, Ge L, Keren B, Timberlake AT, Goto J, Mangano FT, Johnston JM, Butler WE, Warf BC, Smith ER, Schiff SJ, Limbrick DD, Heuer G, Jackson EM, Iskandar BJ, Mane S, Haider S, Guclu B, Bayri Y, Sahin Y, Duncan CC, Apuzzo MLJ, DiLuna ML, Hoffman EJ, Sestan N, Ment LR, Alper SL, Bilguvar K, Geschwind DH, Günel M, Lifton RP, Kahle KT. Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus Nature Medicine 2020, 26: 1754-1765. PMID: 33077954, PMCID: PMC7871900, DOI: 10.1038/s41591-020-1090-2.
- De novo damaging variants associated with congenital heart diseases contribute to the connectomeJi W, Ferdman D, Copel J, Scheinost D, Shabanova V, Brueckner M, Khokha MK, Ment LR. De novo damaging variants associated with congenital heart diseases contribute to the connectome Scientific Reports 2020, 10: 7046. PMID: 32341405, PMCID: PMC7184603, DOI: 10.1038/s41598-020-63928-2.
- Prefrontal Cortical and Behavioral Adaptations to Surgical Delivery Mediated by Metabolic Principles.Taylor-Giorlando M, Scheinost D, Ment L, Rothman D, Horvath TL. Prefrontal Cortical and Behavioral Adaptations to Surgical Delivery Mediated by Metabolic Principles. Cerebral Cortex 2019, 29: 5061-5071. PMID: 30877804, PMCID: PMC6918927, DOI: 10.1093/cercor/bhz046.
- Amygdala functional connectivity is associated with social impairments in preterm born young adultsJohns CB, Lacadie C, Vohr B, Ment LR, Scheinost D. Amygdala functional connectivity is associated with social impairments in preterm born young adults NeuroImage Clinical 2018, 21: 101626. PMID: 30545688, PMCID: PMC6413301, DOI: 10.1016/j.nicl.2018.101626.
- Weak functional connectivity in the human fetal brain prior to preterm birthThomason ME, Scheinost D, Manning JH, Grove LE, Hect J, Marshall N, Hernandez-Andrade E, Berman S, Pappas A, Yeo L, Hassan SS, Constable RT, Ment LR, Romero R. Weak functional connectivity in the human fetal brain prior to preterm birth Scientific Reports 2017, 7: 39286. PMID: 28067865, PMCID: PMC5221666, DOI: 10.1038/srep39286.
- Fine Motor Skill Mediates Visual Memory Ability with Microstructural Neuro-correlates in Cerebellar Peduncles in Prematurely Born AdolescentsThomas AR, Lacadie C, Vohr B, Ment LR, Scheinost D. Fine Motor Skill Mediates Visual Memory Ability with Microstructural Neuro-correlates in Cerebellar Peduncles in Prematurely Born Adolescents Cerebral Cortex 2017, 27: 322-329. PMID: 28108493, PMCID: PMC5939198, DOI: 10.1093/cercor/bhw415.
- Does prenatal stress alter the developing connectome?Scheinost D, Sinha R, Cross SN, Kwon SH, Sze G, Constable RT, Ment LR. Does prenatal stress alter the developing connectome? Pediatric Research 2016, 81: 214-226. PMID: 27673421, PMCID: PMC5313513, DOI: 10.1038/pr.2016.197.
- Blood Pressure in Young Adults Born at Very Low Birth WeightHovi P, Vohr B, Ment LR, Doyle LW, McGarvey L, Morrison KM, Evensen KA, van der Pal S, Grunau RE, Brubakk A, Andersson S, Saigal S, Kajantie E. Blood Pressure in Young Adults Born at Very Low Birth Weight Hypertension 2016, 68: 880-887. PMID: 27572149, DOI: 10.1161/hypertensionaha.116.08167.
- Cerebellar Hemorrhage in the Premature Infant—Time for a Balanced ApproachHirtz D, Ment LR. Cerebellar Hemorrhage in the Premature Infant—Time for a Balanced Approach The Journal Of Pediatrics 2016, 178: 9-10. PMID: 27526623, DOI: 10.1016/j.jpeds.2016.07.036.
- Functional magnetic resonance connectivity studies in infants born preterm: suggestions of proximate and long‐lasting changes in language organizationKwon SH, Scheinost D, Vohr B, Lacadie C, Schneider K, Dai F, Sze G, Constable RT, Ment LR. Functional magnetic resonance connectivity studies in infants born preterm: suggestions of proximate and long‐lasting changes in language organization Developmental Medicine & Child Neurology 2016, 58: 28-34. PMID: 27027605, PMCID: PMC6426123, DOI: 10.1111/dmcn.13043.
- Prenatal stress alters amygdala functional connectivity in preterm neonatesScheinost D, Kwon SH, Lacadie C, Sze G, Sinha R, Constable RT, Ment LR. Prenatal stress alters amygdala functional connectivity in preterm neonates NeuroImage Clinical 2016, 12: 381-388. PMID: 27622134, PMCID: PMC5009231, DOI: 10.1016/j.nicl.2016.08.010.
- Language at rest: A longitudinal study of intrinsic functional connectivity in preterm childrenRowlands MA, Scheinost D, Lacadie C, Vohr B, Li F, Schneider KC, Constable R, Ment LR. Language at rest: A longitudinal study of intrinsic functional connectivity in preterm children NeuroImage Clinical 2016, 11: 149-157. PMID: 26937383, PMCID: PMC4753807, DOI: 10.1016/j.nicl.2016.01.016.
- Genes and environment in neonatal intraventricular hemorrhageMent LR, Ådén U, Bauer CR, Bada HS, Carlo WA, Kaiser JR, Lin A, Cotten CM, Murray J, Page G, Hallman M, Lifton RP, Zhang H, Network O. Genes and environment in neonatal intraventricular hemorrhage Seminars In Perinatology 2015, 39: 592-603. PMID: 26516117, PMCID: PMC4668116, DOI: 10.1053/j.semperi.2015.09.006.
- Alterations in Anatomical Covariance in the Prematurely BornScheinost D, Kwon SH, Lacadie C, Vohr BR, Schneider KC, Papademetris X, Constable RT, Ment LR. Alterations in Anatomical Covariance in the Prematurely Born Cerebral Cortex 2015, 27: 534-543. PMID: 26494796, PMCID: PMC5939217, DOI: 10.1093/cercor/bhv248.
- Preterm birth alters neonatal, functional rich club organizationScheinost D, Kwon SH, Shen X, Lacadie C, Schneider KC, Dai F, Ment LR, Constable RT. Preterm birth alters neonatal, functional rich club organization Brain Structure And Function 2015, 221: 3211-3222. PMID: 26341628, PMCID: PMC4779074, DOI: 10.1007/s00429-015-1096-6.
- Adaptive mechanisms of developing brain: Cerebral lateralization in the prematurely-bornKwon SH, Scheinost D, Lacadie C, Sze G, Schneider KC, Dai F, Constable RT, Ment LR. Adaptive mechanisms of developing brain: Cerebral lateralization in the prematurely-born NeuroImage 2014, 108: 144-150. PMID: 25528658, PMCID: PMC4324328, DOI: 10.1016/j.neuroimage.2014.12.032.
- Adolescents born prematurely with isolated grade 2 haemorrhage in the early 1990s face increased risks of learning challengesVohr BR, Allan W, Katz KH, Schneider K, Tucker R, Ment LR. Adolescents born prematurely with isolated grade 2 haemorrhage in the early 1990s face increased risks of learning challenges Acta Paediatrica 2014, 103: 1066-1071. PMID: 24976311, DOI: 10.1111/apa.12728.
- GABA, Resting-State Connectivity and the Developing BrainKwon SH, Scheinost D, Lacadie C, Benjamin J, Myers EH, Qiu M, Schneider KC, Rothman DL, Constable RT, Ment LR. GABA, Resting-State Connectivity and the Developing Brain Neonatology 2014, 106: 149-155. PMID: 24970028, PMCID: PMC4134402, DOI: 10.1159/000362433.
- Maternal Race, Demography, and Health Care Disparities Impact Risk for Intraventricular Hemorrhage in Preterm NeonatesShankaran S, Lin A, Maller-Kesselman J, Zhang H, O'Shea TM, Bada HS, Kaiser JR, Lifton RP, Bauer CR, Ment LR, Study G. Maternal Race, Demography, and Health Care Disparities Impact Risk for Intraventricular Hemorrhage in Preterm Neonates The Journal Of Pediatrics 2014, 164: 1005-1011.e3. PMID: 24589078, PMCID: PMC4095864, DOI: 10.1016/j.jpeds.2014.01.036.
- Cerebral Lateralization is Protective in the Very Prematurely BornScheinost D, Lacadie C, Vohr BR, Schneider KC, Papademetris X, Constable RT, Ment LR. Cerebral Lateralization is Protective in the Very Prematurely Born Cerebral Cortex 2014, 25: 1858-1866. PMID: 24451659, PMCID: PMC4459290, DOI: 10.1093/cercor/bht430.
- The Role of Neuroimaging in Predicting Neurodevelopmental Outcomes of Preterm NeonatesKwon SH, Vasung L, Ment LR, Huppi PS. The Role of Neuroimaging in Predicting Neurodevelopmental Outcomes of Preterm Neonates Clinics In Perinatology 2013, 41: 257-283. PMID: 24524459, DOI: 10.1016/j.clp.2013.10.003.
- Gene–environment interactions in severe intraventricular hemorrhage of preterm neonatesMent LR, Ådén U, Lin A, Kwon SH, Choi M, Hallman M, Lifton RP, Zhang H, Bauer CR. Gene–environment interactions in severe intraventricular hemorrhage of preterm neonates Pediatric Research 2013, 75: 241-250. PMID: 24192699, PMCID: PMC3946468, DOI: 10.1038/pr.2013.195.
- Hypoxia-Induced Developmental Delays of Inhibitory Interneurons Are Reversed by Environmental Enrichment in the Postnatal Mouse ForebrainKomitova M, Xenos D, Salmaso N, Tran KM, Brand T, Schwartz ML, Ment L, Vaccarino FM. Hypoxia-Induced Developmental Delays of Inhibitory Interneurons Are Reversed by Environmental Enrichment in the Postnatal Mouse Forebrain Journal Of Neuroscience 2013, 33: 13375-13387. PMID: 23946395, PMCID: PMC3742925, DOI: 10.1523/jneurosci.5286-12.2013.
- Candidate Gene Analysis: Severe Intraventricular Hemorrhage in Inborn Preterm NeonatesÅdén U, Lin A, Carlo W, Leviton A, Murray JC, Hallman M, Lifton RP, Zhang H, Ment LR, Group G. Candidate Gene Analysis: Severe Intraventricular Hemorrhage in Inborn Preterm Neonates The Journal Of Pediatrics 2013, 163: 1503-1506.e1. PMID: 23896193, PMCID: PMC3812267, DOI: 10.1016/j.jpeds.2013.06.025.
- Systemic Inflammation, Intraventricular Hemorrhage, and White Matter InjuryLeviton A, Allred EN, Dammann O, Engelke S, Fichorova RN, Hirtz D, Kuban KC, Ment LR, O’shea T, Paneth N, Shah B, Schreiber MD. Systemic Inflammation, Intraventricular Hemorrhage, and White Matter Injury Journal Of Child Neurology 2012, 28: 1637-1645. PMID: 23112243, PMCID: PMC4166653, DOI: 10.1177/0883073812463068.
- A left cerebellar pathway mediates language in prematurely-born young adultsConstable RT, Vohr BR, Scheinost D, Benjamin JR, Fulbright RK, Lacadie C, Schneider KC, Katz KH, Zhang H, Papademetris X, Ment LR. A left cerebellar pathway mediates language in prematurely-born young adults NeuroImage 2012, 64: 371-378. PMID: 22982585, PMCID: PMC3508203, DOI: 10.1016/j.neuroimage.2012.09.008.
- Environmental Enrichment Increases the GFAP+ Stem Cell Pool and Reverses Hypoxia-Induced Cognitive Deficits in Juvenile MiceSalmaso N, Silbereis J, Komitova M, Mitchell P, Chapman K, Ment LR, Schwartz ML, Vaccarino FM. Environmental Enrichment Increases the GFAP+ Stem Cell Pool and Reverses Hypoxia-Induced Cognitive Deficits in Juvenile Mice Journal Of Neuroscience 2012, 32: 8930-8939. PMID: 22745493, PMCID: PMC3399175, DOI: 10.1523/jneurosci.1398-12.2012.
- The intrinsic connectivity distribution: A novel contrast measure reflecting voxel level functional connectivityScheinost D, Benjamin J, Lacadie CM, Vohr B, Schneider KC, Ment LR, Papademetris X, Constable RT. The intrinsic connectivity distribution: A novel contrast measure reflecting voxel level functional connectivity NeuroImage 2012, 62: 1510-1519. PMID: 22659477, PMCID: PMC3538880, DOI: 10.1016/j.neuroimage.2012.05.073.
- Evidence for Catch-up in Cognition and Receptive Vocabulary Among Adolescents Born Very PretermLuu TM, Vohr BR, Allan W, Schneider KC, Ment LR. Evidence for Catch-up in Cognition and Receptive Vocabulary Among Adolescents Born Very Preterm Pediatrics 2011, 128: 313-322. PMID: 21768322, PMCID: PMC3146356, DOI: 10.1542/peds.2010-2655.
- Cortical Glial Fibrillary Acidic Protein-Positive Cells Generate Neurons after Perinatal Hypoxic InjuryBi B, Salmaso N, Komitova M, Simonini MV, Silbereis J, Cheng E, Kim J, Luft S, Ment LR, Horvath TL, Schwartz ML, Vaccarino FM. Cortical Glial Fibrillary Acidic Protein-Positive Cells Generate Neurons after Perinatal Hypoxic Injury Journal Of Neuroscience 2011, 31: 9205-9221. PMID: 21697371, PMCID: PMC3142780, DOI: 10.1523/jneurosci.0518-11.2011.
- Consequence of Preterm Birth in Early Adolescence: The Role of Language on Auditory Short-term MemoryFraello D, Maller-Kesselman J, Vohr B, Katz KH, Kesler S, Schneider K, Reiss A, Ment L, Spann MN. Consequence of Preterm Birth in Early Adolescence: The Role of Language on Auditory Short-term Memory Journal Of Child Neurology 2011, 26: 738-742. PMID: 21471553, PMCID: PMC3581362, DOI: 10.1177/0883073810391904.
- Executive and Memory Function in Adolescents Born Very PretermLuu TM, Ment L, Allan W, Schneider K, Vohr BR. Executive and Memory Function in Adolescents Born Very Preterm Pediatrics 2011, 127: e639-e646. PMID: 21300680, PMCID: PMC3065148, DOI: 10.1542/peds.2010-1421.
- Microstructural and Functional Connectivity in the Developing Preterm BrainLubsen J, Vohr B, Myers E, Hampson M, Lacadie C, Schneider KC, Katz KH, Constable RT, Ment LR. Microstructural and Functional Connectivity in the Developing Preterm Brain Seminars In Perinatology 2011, 35: 34-43. PMID: 21255705, PMCID: PMC3063450, DOI: 10.1053/j.semperi.2010.10.006.
- Preterm birth results in alterations in neural connectivity at age 16 yearsMullen KM, Vohr BR, Katz KH, Schneider KC, Lacadie C, Hampson M, Makuch RW, Reiss AL, Constable RT, Ment LR. Preterm birth results in alterations in neural connectivity at age 16 years NeuroImage 2010, 54: 2563-2570. PMID: 21073965, PMCID: PMC3020252, DOI: 10.1016/j.neuroimage.2010.11.019.
- Early predictors of hypertension in prematurely born adolescentsVohr BR, Allan W, Katz KH, Schneider KC, Ment LR. Early predictors of hypertension in prematurely born adolescents Acta Paediatrica 2010, 99: 1812-1818. PMID: 20586997, PMCID: PMC2970763, DOI: 10.1111/j.1651-2227.2010.01926.x.
- Astroglial cells in the external granular layer are precursors of cerebellar granule neurons in neonatesSilbereis J, Heintz T, Taylor MM, Ganat Y, Ment LR, Bordey A, Vaccarino F. Astroglial cells in the external granular layer are precursors of cerebellar granule neurons in neonates Molecular And Cellular Neuroscience 2010, 44: 362-373. PMID: 20470892, PMCID: PMC2900521, DOI: 10.1016/j.mcn.2010.05.001.
- Functional connectivity to a right hemisphere language center in prematurely born adolescentsMyers EH, Hampson M, Vohr B, Lacadie C, Frost SJ, Pugh KR, Katz KH, Schneider KC, Makuch RW, Constable RT, Ment LR. Functional connectivity to a right hemisphere language center in prematurely born adolescents NeuroImage 2010, 51: 1445-1452. PMID: 20347043, PMCID: PMC2872040, DOI: 10.1016/j.neuroimage.2010.03.049.
- Long-term Outcome of Preterm Infants and the Role of NeuroimagingMyers E, Ment LR. Long-term Outcome of Preterm Infants and the Role of Neuroimaging Clinics In Perinatology 2009, 36: 773-789. PMID: 19944835, PMCID: PMC3808964, DOI: 10.1016/j.clp.2009.07.008.
- COL4A1 Mutation in Preterm Intraventricular HemorrhageBilguvar K, DiLuna ML, Bizzarro MJ, Bayri Y, Schneider KC, Lifton RP, Gunel M, Ment LR. COL4A1 Mutation in Preterm Intraventricular Hemorrhage The Journal Of Pediatrics 2009, 155: 743-745. PMID: 19840616, PMCID: PMC2884156, DOI: 10.1016/j.jpeds.2009.04.014.
- Imaging biomarkers of outcome in the developing preterm brainMent LR, Hirtz D, Hüppi PS. Imaging biomarkers of outcome in the developing preterm brain The Lancet Neurology 2009, 8: 1042-1055. PMID: 19800293, DOI: 10.1016/s1474-4422(09)70257-1.
- Mutations in the Type IV Collagens, COL4A1 and COL4A2 are Associated with Intraventricular Hemorrhage in Preterm Infants: 956.DiLuna ML, Bilguvar K, Louvi A, Bizzarro M, Bayrakli F, Bayri Y, Bydon M, Schneider K, Duncan CC, State M, Lifton RP, Ment LR, Gunel M. Mutations in the Type IV Collagens, COL4A1 and COL4A2 are Associated with Intraventricular Hemorrhage in Preterm Infants: 956. Neurosurgery 2009, 65: 419. PMID: 28173201, DOI: 10.1227/01.neu.0000358727.92507.ea.
- Trajectories of Receptive Language Development From 3 to 12 Years of Age for Very Preterm ChildrenLuu TM, Vohr BR, Schneider KC, Katz KH, Tucker R, Allan WC, Ment LR. Trajectories of Receptive Language Development From 3 to 12 Years of Age for Very Preterm Children Pediatrics 2009, 124: 333-341. PMID: 19564317, PMCID: PMC2704989, DOI: 10.1542/peds.2008-2587.
- Alterations in neural connectivity in preterm children at school ageGozzo Y, Vohr B, Lacadie C, Hampson M, Katz KH, Maller-Kesselman J, Schneider KC, Peterson BS, Rajeevan N, Makuch RW, Constable RT, Ment LR. Alterations in neural connectivity in preterm children at school age NeuroImage 2009, 48: 458-463. PMID: 19560547, PMCID: PMC2775072, DOI: 10.1016/j.neuroimage.2009.06.046.
- Dementia in a Child with Myotubular MyopathyMcCrea HJ, Kretz C, Laporte J, Ment LR. Dementia in a Child with Myotubular Myopathy Pediatric Neurology 2009, 40: 483-485. PMID: 19433289, PMCID: PMC3808886, DOI: 10.1016/j.pediatrneurol.2009.01.005.
- Modeling premature brain injury and recoveryScafidi J, Fagel DM, Ment LR, Vaccarino FM. Modeling premature brain injury and recovery International Journal Of Developmental Neuroscience 2009, 27: 863-871. PMID: 19482072, PMCID: PMC2783901, DOI: 10.1016/j.ijdevneu.2009.05.009.
- Hypoxic Injury during Neonatal Development in Murine Brain: Correlation between In Vivo DTI Findings and Behavioral AssessmentChahboune H, Ment LR, Stewart WB, Rothman DL, Vaccarino FM, Hyder F, Schwartz ML. Hypoxic Injury during Neonatal Development in Murine Brain: Correlation between In Vivo DTI Findings and Behavioral Assessment Cerebral Cortex 2009, 19: 2891-2901. PMID: 19380380, PMCID: PMC2774398, DOI: 10.1093/cercor/bhp068.
- Randomized Clinical Trials in ChildrenMent LR, Shinnar S. Randomized Clinical Trials in Children 2009, 25: 158-162. PMID: 19478517, DOI: 10.1159/000209495.
- Lasting Effects of Preterm Birth and Neonatal Brain Hemorrhage at 12 Years of AgeLuu TM, Ment LR, Schneider KC, Katz KH, Allan WC, Vohr BR. Lasting Effects of Preterm Birth and Neonatal Brain Hemorrhage at 12 Years of Age Pediatrics 2009, 123: 1037-1044. PMID: 19255037, PMCID: PMC2651566, DOI: 10.1542/peds.2008-1162.
- Longitudinal Brain Volume Changes in Preterm and Term Control Subjects During Late Childhood and AdolescenceMent LR, Kesler S, Vohr B, Katz KH, Baumgartner H, Schneider KC, Delancy S, Silbereis J, Duncan CC, Constable RT, Makuch RW, Reiss AL. Longitudinal Brain Volume Changes in Preterm and Term Control Subjects During Late Childhood and Adolescence Pediatrics 2009, 123: 503-511. PMID: 19171615, PMCID: PMC2679898, DOI: 10.1542/peds.2008-0025.
- Precursors with Glial Fibrillary Acidic Protein Promoter Activity Transiently Generate GABA Interneurons in the Postnatal CerebellumSilbereis J, Cheng E, Ganat YM, Ment LR, Vaccarino FM. Precursors with Glial Fibrillary Acidic Protein Promoter Activity Transiently Generate GABA Interneurons in the Postnatal Cerebellum Stem Cells 2009, 27: 1152-1163. PMID: 19418461, PMCID: PMC2903623, DOI: 10.1002/stem.18.
- Fgfr1 Is Required for Cortical Regeneration and Repair after Perinatal HypoxiaFagel DM, Ganat Y, Cheng E, Silbereis J, Ohkubo Y, Ment LR, Vaccarino FM. Fgfr1 Is Required for Cortical Regeneration and Repair after Perinatal Hypoxia Journal Of Neuroscience 2009, 29: 1202-1211. PMID: 19176828, PMCID: PMC2768410, DOI: 10.1523/jneurosci.4516-08.2009.
- Alterations in functional connectivity for language in prematurely born adolescentsSchafer RJ, Lacadie C, Vohr B, Kesler SR, Katz KH, Schneider KC, Pugh KR, Makuch RW, Reiss AL, Constable RT, Ment LR. Alterations in functional connectivity for language in prematurely born adolescents Brain 2009, 132: 661-670. PMID: 19158105, PMCID: PMC2664451, DOI: 10.1093/brain/awn353.
- The Diagnosis, Management, and Postnatal Prevention of Intraventricular Hemorrhage in the Preterm NeonateMcCrea HJ, Ment LR. The Diagnosis, Management, and Postnatal Prevention of Intraventricular Hemorrhage in the Preterm Neonate Clinics In Perinatology 2008, 35: 777-792. PMID: 19026340, PMCID: PMC2901530, DOI: 10.1016/j.clp.2008.07.014.
- Preterm birth and the developing brainMent LR, Vohr BR. Preterm birth and the developing brain The Lancet Neurology 2008, 7: 378-379. PMID: 18420149, PMCID: PMC2762422, DOI: 10.1016/s1474-4422(08)70073-5.
- Sickle cell disease complicated by post‐streptococcal glomerulonephritis, cerebral hemorrhage and reversible posterior leucoencephalopathy syndromePashankar FD, Ment LR, Pearson HA. Sickle cell disease complicated by post‐streptococcal glomerulonephritis, cerebral hemorrhage and reversible posterior leucoencephalopathy syndrome Pediatric Blood & Cancer 2008, 50: 864-866. PMID: 17973321, DOI: 10.1002/pbc.21321.
- Prematurely Born Children Demonstrate White Matter Microstructural Differences at 12 Years of Age, Relative to Term Control Subjects: An Investigation of Group and Gender EffectsConstable RT, Ment LR, Vohr BR, Kesler SR, Fulbright RK, Lacadie C, Delancy S, Katz KH, Schneider KC, Schafer RJ, Makuch RW, Reiss AR. Prematurely Born Children Demonstrate White Matter Microstructural Differences at 12 Years of Age, Relative to Term Control Subjects: An Investigation of Group and Gender Effects Pediatrics 2008, 121: 306-316. PMID: 18245422, DOI: 10.1542/peds.2007-0414.
- Brain Volume Reductions within Multiple Cognitive Systems in Male Preterm Children at Age TwelveKesler SR, Reiss AL, Vohr B, Watson C, Schneider KC, Katz KH, Maller-Kesselman J, Silbereis J, Constable RT, Makuch RW, Ment LR. Brain Volume Reductions within Multiple Cognitive Systems in Male Preterm Children at Age Twelve The Journal Of Pediatrics 2007, 152: 513-520.e1. PMID: 18346506, PMCID: PMC3270939, DOI: 10.1016/j.jpeds.2007.08.009.
- Injury and recovery in the developing brain: evidence from functional MRI studies of prematurely born childrenMent LR, Constable RT. Injury and recovery in the developing brain: evidence from functional MRI studies of prematurely born children Nature Reviews Neurology 2007, 3: 558-571. PMID: 17914344, PMCID: PMC2673538, DOI: 10.1038/ncpneuro0616.
- Neonatal Seizures: Multicenter Variability in Current Treatment PracticesBartha AI, Shen J, Katz KH, Mischel RE, Yap KR, Ivacko JA, Andrews EM, Ferriero DM, Ment LR, Silverstein FS. Neonatal Seizures: Multicenter Variability in Current Treatment Practices Pediatric Neurology 2007, 37: 85-90. PMID: 17675022, DOI: 10.1016/j.pediatrneurol.2007.04.003.
- Neurodevelopment of C57B/L6 mouse brain assessed by in vivo diffusion tensor imagingChahboune H, Ment LR, Stewart WB, Ma X, Rothman DL, Hyder F. Neurodevelopment of C57B/L6 mouse brain assessed by in vivo diffusion tensor imaging NMR In Biomedicine 2007, 20: 375-382. PMID: 17451176, DOI: 10.1002/nbm.1130.
- Astroglial Cells in Development, Regeneration, and RepairVaccarino FM, Fagel DM, Ganat Y, Maragnoli ME, Ment LR, Ohkubo Y, Schwartz ML, Silbereis J, Smith KM. Astroglial Cells in Development, Regeneration, and Repair The Neuroscientist 2007, 13: 173-185. PMID: 17404377, DOI: 10.1177/1073858406298336.
- Functional analysis of a novel potassium channel (KCNA1) mutation in hereditary myokymiaChen H, von Hehn C, Kaczmarek LK, Ment LR, Pober BR, Hisama FM. Functional analysis of a novel potassium channel (KCNA1) mutation in hereditary myokymia Neurogenetics 2006, 8: 131-135. PMID: 17136396, PMCID: PMC1820748, DOI: 10.1007/s10048-006-0071-z.
- Genetic Susceptibility to Retinopathy of PrematurityBizzarro MJ, Hussain N, Jonsson B, Feng R, Ment LR, Gruen JR, Zhang H, Bhandari V. Genetic Susceptibility to Retinopathy of Prematurity Pediatrics 2006, 118: 1858-1863. PMID: 17079555, DOI: 10.1542/peds.2006-1088.
- Cortical recruitment patterns in children born prematurely compared with control subjects during a passive listening functional magnetic resonance imaging taskMent LR, Peterson BS, Vohr B, Allan W, Schneider KC, Lacadie C, Katz KH, Maller-Kesselman J, Pugh K, Duncan CC, Makuch RW, Constable RT. Cortical recruitment patterns in children born prematurely compared with control subjects during a passive listening functional magnetic resonance imaging task The Journal Of Pediatrics 2006, 149: 490-498.e2. PMID: 17011320, PMCID: PMC2386989, DOI: 10.1016/j.jpeds.2006.06.007.
- A Functional Magnetic Resonance Imaging Study of the Long-term Influences of Early Indomethacin Exposure on Language Processing in the Brains of Prematurely Born ChildrenMent LR, Peterson BS, Meltzer JA, Vohr B, Allan W, Katz KH, Lacadie C, Schneider KC, Duncan CC, Makuch RW, Constable RT. A Functional Magnetic Resonance Imaging Study of the Long-term Influences of Early Indomethacin Exposure on Language Processing in the Brains of Prematurely Born Children Pediatrics 2006, 118: 961-970. PMID: 16950986, PMCID: PMC2364718, DOI: 10.1542/peds.2005-2870.
- Early Postnatal Astroglial Cells Produce Multilineage Precursors and Neural Stem Cells In VivoGanat YM, Silbereis J, Cave C, Ngu H, Anderson GM, Ohkubo Y, Ment LR, Vaccarino FM. Early Postnatal Astroglial Cells Produce Multilineage Precursors and Neural Stem Cells In Vivo Journal Of Neuroscience 2006, 26: 8609-8621. PMID: 16914687, PMCID: PMC6674357, DOI: 10.1523/jneurosci.2532-06.2006.
- Familial and Genetic Susceptibility to Major Neonatal Morbidities in Preterm TwinsBhandari V, Bizzarro MJ, Shetty A, Zhong X, Page GP, Zhang H, Ment LR, Gruen JR. Familial and Genetic Susceptibility to Major Neonatal Morbidities in Preterm Twins Pediatrics 2006, 117: 1901-1906. PMID: 16740829, DOI: 10.1542/peds.2005-1414.
- Cortical neurogenesis enhanced by chronic perinatal hypoxiaFagel DM, Ganat Y, Silbereis J, Ebbitt T, Stewart W, Zhang H, Ment LR, Vaccarino FM. Cortical neurogenesis enhanced by chronic perinatal hypoxia Experimental Neurology 2006, 199: 77-91. PMID: 15916762, DOI: 10.1016/j.expneurol.2005.04.006.
- Grade 3 to 4 Intraventricular Hemorrhage and Bayley Scores Predict OutcomeMent LR, Allan WC, Makuch RW, Vohr B. Grade 3 to 4 Intraventricular Hemorrhage and Bayley Scores Predict Outcome Pediatrics 2005, 116: 1597-1598. PMID: 16322189, DOI: 10.1542/peds.2005-2020.
- Increased temporal lobe gyrification in preterm childrenKesler SR, Vohr B, Schneider KC, Katz KH, Makuch RW, Reiss AL, Ment LR. Increased temporal lobe gyrification in preterm children Neuropsychologia 2005, 44: 445-453. PMID: 15985272, DOI: 10.1016/j.neuropsychologia.2005.05.015.
- Prevention of intraventricular hemorrhage by indomethacin in male preterm infantsMent LR, Vohr BR, Makuch RW, Westerveld M, Katz KH, Schneider KC, Duncan CC, Ehrenkranz R, Oh W, Philip AG, Scott DT, Allan WC. Prevention of intraventricular hemorrhage by indomethacin in male preterm infants The Journal Of Pediatrics 2004, 145: 832-834. PMID: 15580211, DOI: 10.1016/j.jpeds.2004.07.035.
- Chronic neonatal hypoxia leads to long term decreases in the volume and cell number of the rat cerebral cortexSchwartz ML, Vaccarino F, Chacon M, Yan WL, Ment LR, Stewart WB. Chronic neonatal hypoxia leads to long term decreases in the volume and cell number of the rat cerebral cortex Seminars In Perinatology 2004, 28: 379-388. PMID: 15693394, DOI: 10.1053/j.semperi.2004.10.009.
- Preterm birth: A cost benefit analysisRushing S, Ment LR. Preterm birth: A cost benefit analysis Seminars In Perinatology 2004, 28: 444-450. PMID: 15693401, DOI: 10.1053/j.semperi.2004.10.007.
- Volumetric analysis of regional cerebral development in preterm childrenKesler SR, Ment LR, Vohr B, Pajot SK, Schneider KC, Katz KH, Ebbitt TB, Duncan CC, Makuch RW, Reiss AL. Volumetric analysis of regional cerebral development in preterm children Pediatric Neurology 2004, 31: 318-325. PMID: 15519112, PMCID: PMC3061618, DOI: 10.1016/j.pediatrneurol.2004.06.008.
- Neonatal hypoxia suppresses oligodendrocyte Nogo-A and increases axonal sprouting in a rodent model for human prematurityWeiss J, Takizawa B, McGee A, Stewart WB, Zhang H, Ment L, Schwartz M, Strittmatter S. Neonatal hypoxia suppresses oligodendrocyte Nogo-A and increases axonal sprouting in a rodent model for human prematurity Experimental Neurology 2004, 189: 141-149. PMID: 15296844, DOI: 10.1016/j.expneurol.2004.05.018.
- Sex differences in cerebral volumes of 8-year-olds born pretermReiss AL, Kesler SR, Vohr B, Duncan CC, Katz KH, Pajot S, Schneider KC, Makuch RW, Ment LR. Sex differences in cerebral volumes of 8-year-olds born preterm The Journal Of Pediatrics 2004, 145: 242-249. PMID: 15289777, DOI: 10.1016/j.jpeds.2004.04.031.
- Injury and repair in developing brainVaccarino FM, Ment LR. Injury and repair in developing brain Archives Of Disease In Childhood - Fetal And Neonatal Edition 2004, 89: f190. PMID: 15102716, PMCID: PMC1721670, DOI: 10.1136/adc.2003.043661.
- Fetal strokeÖzduman K, Pober BR, Barnes P, Copel JA, Ogle EA, Duncan CC, Ment LR. Fetal stroke Pediatric Neurology 2004, 30: 151-162. PMID: 15033196, DOI: 10.1016/j.pediatrneurol.2003.08.004.
- An Evidence-Based Approach to Predicting Low IQ in Very Preterm Infants From the Neurological Examination: Outcome Data From the Indomethacin Intraventricular Hemorrhage Prevention TrialPleacher MD, Vohr BR, Katz KH, Ment LR, Allan WC. An Evidence-Based Approach to Predicting Low IQ in Very Preterm Infants From the Neurological Examination: Outcome Data From the Indomethacin Intraventricular Hemorrhage Prevention Trial Pediatrics 2004, 113: 416-419. PMID: 14754962, DOI: 10.1542/peds.113.2.416.
- A1 adenosine receptors mediate hypoxia-induced ventriculomegalyTurner CP, Seli M, Ment L, Stewart W, Yan H, Johansson B, Fredholm BB, Blackburn M, Rivkees SA. A1 adenosine receptors mediate hypoxia-induced ventriculomegaly Proceedings Of The National Academy Of Sciences Of The United States Of America 2003, 100: 11718-11722. PMID: 12975523, PMCID: PMC208824, DOI: 10.1073/pnas.1931975100.
- Regional Brain Volumes and Their Later Neurodevelopmental Correlates in Term and Preterm InfantsPeterson BS, Anderson AW, Ehrenkranz R, Staib LH, Tageldin M, Colson E, Gore JC, Duncan CC, Makuch R, Ment LR. Regional Brain Volumes and Their Later Neurodevelopmental Correlates in Term and Preterm Infants Pediatrics 2003, 111: 939-948. PMID: 12728069, DOI: 10.1542/peds.111.5.939.
- School-Age Outcomes of Very Low Birth Weight Infants in the Indomethacin Intraventricular Hemorrhage Prevention TrialVohr BR, Allan WC, Westerveld M, Schneider KC, Katz KH, Makuch RW, Ment LR. School-Age Outcomes of Very Low Birth Weight Infants in the Indomethacin Intraventricular Hemorrhage Prevention Trial Pediatrics 2003, 111: e340-e346. PMID: 12671149, DOI: 10.1542/peds.111.4.e340.
- Change in Cognitive Function Over Time in Very Low-Birth-Weight InfantsMent LR, Vohr B, Allan W, Katz KH, Schneider KC, Westerveld M, Duncan CC, Makuch RW. Change in Cognitive Function Over Time in Very Low-Birth-Weight Infants JAMA 2003, 289: 705-711. PMID: 12585948, DOI: 10.1001/jama.289.6.705.
- A Functional Magnetic Resonance Imaging Study of Language Processing and Its Cognitive Correlates in Prematurely Born ChildrenPeterson BS, Vohr B, Kane MJ, Whalen DH, Schneider KC, Katz KH, Zhang H, Duncan CC, Makuch R, Gore JC, Ment LR. A Functional Magnetic Resonance Imaging Study of Language Processing and Its Cognitive Correlates in Prematurely Born Children Pediatrics 2002, 110: 1153-1162. PMID: 12456913, DOI: 10.1542/peds.110.6.1153.
- Case report: a young boy with painful leg swellingMiller DT, Ment LR. Case report: a young boy with painful leg swelling Current Opinion In Pediatrics 2002, 14: 731-734. PMID: 12436046, DOI: 10.1097/00008480-200212000-00017.
- Disrupted synaptic development in the hypoxic newborn brainCurristin SM, Cao A, Stewart WB, Zhang H, Madri JA, Morrow JS, Ment LR. Disrupted synaptic development in the hypoxic newborn brain Proceedings Of The National Academy Of Sciences Of The United States Of America 2002, 99: 15729-15734. PMID: 12438650, PMCID: PMC137784, DOI: 10.1073/pnas.232568799.
- Paracrine and Autocrine Functions of Neuronal Vascular Endothelial Growth Factor (VEGF) in the Central Nervous System*Ogunshola OO, Antic A, Donoghue MJ, Fan SY, Kim H, Stewart WB, Madri JA, Ment LR. Paracrine and Autocrine Functions of Neuronal Vascular Endothelial Growth Factor (VEGF) in the Central Nervous System* Journal Of Biological Chemistry 2002, 277: 11410-11415. PMID: 11777931, DOI: 10.1074/jbc.m111085200.
Clinical Trials
Conditions | Study Title |
---|---|
Children's Health | Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-ACQUIRE) (I-ACQUIRE) |
Diseases of the Cardiovascular System | Genomic Basis of Neurodevelopmental and Brain Outcomes in Congenital Heart Disease (CHD Brain and Genes) |
Child Development & Autism | Understanding Neurodevelopment in Autism |