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INFORMATION FOR

Christian Pettker, MD

Professor of Obstetrics, Gynecology and Reproductive Sciences; Chief Patient Safety Officer and Associate Chief Quality Officer, Yale Medicine and Yale New Haven Health; Chief of Obstetrics; Vice Chair of Quality, Obstetrics, Gynecology & Reproductive Sciences

Research Summary

Dr. Pettker’s research interests relate to clinical and outcomes–based research, particularly in labor and delivery. His work continues to focus on patient safety and quality improvement in obstetrics and hospital care.

He is the site Principal Investigator for the NIH/NICHD sponsored Maternal-Fetal Medicine Unit (MFMU) Network.

Extensive Research Description

Maternal-Fetal Medicine Unit Network (MFMU)

COVID-19 in obstetrics; COVID-19 testing

Shoulder dystocia documentation and outcomes

Impact of patient safety on medical liability claims and payment

Maternal early warning systems

Ultrasound at periviability

Surgical site infection reduction

Coauthors

Research Interests

Cesarean Section; Fetal Membranes, Premature Rupture; Labor, Obstetric; Labor, Induced; Obstetrics; Outcome and Process Assessment, Health Care; Quality Assurance, Health Care; Quality of Health Care; Safety; Epidemiologic Research Design; Randomized Controlled Trial; Evidence-Based Medicine; Delivery, Obstetric; Premature Birth

Public Health Interests

Health Care Quality, Efficiency; Health Care Management

Research Images

Selected Publications

  • Neonatal outcomes by delivery indication after administration of antenatal late preterm corticosteroidsDeshmukh U, Lundsberg L, Pettker C, Rouse D, Reddy U. Neonatal outcomes by delivery indication after administration of antenatal late preterm corticosteroids AJOG Global Reports 2022, 2: 100097. DOI: 10.1016/j.xagr.2022.100097.
  • Improving the identification of equity-related adverse events in gynecologyFan L, Pettker C, Stanwood N, Sheth S. Improving the identification of equity-related adverse events in gynecology American Journal Of Obstetrics And Gynecology 2022, 226: s1285. DOI: 10.1016/j.ajog.2021.12.140.
  • Antibiotics for Preterm Premature Rupture of MembranesKohari K, Pettker C. Antibiotics for Preterm Premature Rupture of Membranes 2021, 43-47. DOI: 10.1093/med/9780190947088.003.0008.
  • Improvement of Operative Vaginal Delivery Training in ResidencyNegi M, Espinal M, Holveck B, Mehlhaff K, Cron J, Pettker C. Improvement of Operative Vaginal Delivery Training in Residency Obstetrics And Gynecology 2020, 135: 75s. DOI: 10.1097/01.aog.0000664884.60120.a8.
  • 545: Putting teamwork to the test: a randomized trial of collaboration in electronic fetal monitoring (EFM)Mehlhaff K, Pettker C, Hosier H, Lipkind H, Reddy U, Tomlinson M, Ball B, Lundsberg L, Raab C. 545: Putting teamwork to the test: a randomized trial of collaboration in electronic fetal monitoring (EFM) American Journal Of Obstetrics And Gynecology 2020, 222: s351. DOI: 10.1016/j.ajog.2019.11.561.
  • 158: The association of delivery indication with neonatal outcomes in the late preterm periodDeshmukh U, Lundsberg L, Pettker C, Rouse D, Reddy U. 158: The association of delivery indication with neonatal outcomes in the late preterm period American Journal Of Obstetrics And Gynecology 2020, 222: s115. DOI: 10.1016/j.ajog.2019.11.174.
  • 156: Clinical management of deliveries resulting in hypoxic ischemic encephalopathyHehir M, Friedman A, Andrikopoulou M, D'Alton M, DiVito M, Havens S, Huang Y, Jain J, Mehlhaff K, Pettker C, Seligman N, Walden B, Berkowitz R. 156: Clinical management of deliveries resulting in hypoxic ischemic encephalopathy American Journal Of Obstetrics And Gynecology 2020, 222: s113-s114. DOI: 10.1016/j.ajog.2019.11.172.
  • Hospital Variation in Utilization and Success of Trial of Labor After a Prior CesareanXu X, Lee H, Lin H, Lundsberg L, Campbell K, Lipkind H, Pettker C, Illuzzi J. Hospital Variation in Utilization and Success of Trial of Labor After a Prior Cesarean Obstetric Anesthesia Digest 2019, 39: 190-190. DOI: 10.1097/01.aoa.0000603684.07921.7c.
  • Hospital Variation in Utilization and Success of Trial of Labor After a Prior CesareanXu X, Lee H, Lin H, Lundsberg L, Campbell K, Lipkind H, Pettker C, Illuzzi J. Hospital Variation in Utilization and Success of Trial of Labor After a Prior Cesarean Obstetrical & Gynecological Survey 2019, 74: 326-328. DOI: 10.1097/01.ogx.0000559949.47029.19.
  • Predicting Neonatal Pathologic Disposition From Cardiotocography Using Machine Learning [25A]Freedman I, Agarwal A, Doilicho N, Cohen E, Pettker C, Copel J. Predicting Neonatal Pathologic Disposition From Cardiotocography Using Machine Learning [25A] Obstetrics And Gynecology 2019, 133: 16s-16s. DOI: 10.1097/01.aog.0000559372.82367.9f.
  • Results From an Multidisciplinary Severe Maternal Morbidity Review at a Tertiary Academic Medical Center [23P]Campbell K, Grechukhina O, Abdel-Razeq S, Raab C, Pettker C, Lipkind H. Results From an Multidisciplinary Severe Maternal Morbidity Review at a Tertiary Academic Medical Center [23P] Obstetrics And Gynecology 2019, 133: 176s-176s. DOI: 10.1097/01.aog.0000559487.48795.79.
  • Adherence to New Definitions of Labor Arrest and Failed Induction Decreases Primary Cesareans [16F]Greenberg J, Cross S, Pettker C, Lee Illuzzi J. Adherence to New Definitions of Labor Arrest and Failed Induction Decreases Primary Cesareans [16F] Obstetrics And Gynecology 2019, 133: 66s-66s. DOI: 10.1097/01.aog.0000559047.40111.6d.
  • 301: The impact of mode of delivery on subsequent pregnancy outcomes after periviable birthDesai A, Krenitsky N, Merriam A, Kohari K, Pettker C, Cross S. 301: The impact of mode of delivery on subsequent pregnancy outcomes after periviable birth American Journal Of Obstetrics And Gynecology 2019, 220: s212-s213. DOI: 10.1016/j.ajog.2018.11.322.
  • Implementing an Internet‐based Decision Aid in Ethnically Diverse Prenatal Care Settings: Reducing Disparities through Shared Decision Making about Birth after CesareanShorten A, Shorten B, Fagerlin A, Illuzzi J, Kennedy H, Pettker C, Raju D, Whittemore R. Implementing an Internet‐based Decision Aid in Ethnically Diverse Prenatal Care Settings: Reducing Disparities through Shared Decision Making about Birth after Cesarean Journal Of Midwifery & Women's Health 2018, 63: 625-626. DOI: 10.1111/jmwh.12916.
  • Severe Maternal Morbidity and Mortality During Delivery Hospitalization of Class I, II, III, and Super Obese Women [39I]Platner M, Ackerman C, Xu X, Campbell K, Pettker C, Lipkind H. Severe Maternal Morbidity and Mortality During Delivery Hospitalization of Class I, II, III, and Super Obese Women [39I] Obstetrics And Gynecology 2018, 131: 107s-108s. DOI: 10.1097/01.aog.0000533465.62923.b2.
  • Improving Patient Safety Through Team TrainingPettker C, Funai E. Improving Patient Safety Through Team Training 2018, 169-176. DOI: 10.1017/9781139505826.020.
  • 765: Gestational weight gain and severe maternal morbidity and mortality during delivery hospitalizationPlatner M, Ackerman C, Xu X, Pettker C, Campbell K, Lipkind H. 765: Gestational weight gain and severe maternal morbidity and mortality during delivery hospitalization American Journal Of Obstetrics And Gynecology 2018, 218: s458. DOI: 10.1016/j.ajog.2017.11.297.
  • 833: Severe maternal morbidity associated with hypertensive disorders of pregnancy after regionalization of perinatal care in New York CityAckerman C, Pettker C, Goffman D, Campbell K, Platner M, Zu X, Abdel-Razeq S, Chung S, Lipkind H. 833: Severe maternal morbidity associated with hypertensive disorders of pregnancy after regionalization of perinatal care in New York City American Journal Of Obstetrics And Gynecology 2018, 218: s496. DOI: 10.1016/j.ajog.2017.11.366.
  • 315: Hypertensive disorders of pregnancy and severe cardiovascular morbidity in the immediate postpartum periodAckerman C, Platner M, Pettker C, Spatz E, Paidas M, Zu X, Campbell K, Chung S, Lipkind H. 315: Hypertensive disorders of pregnancy and severe cardiovascular morbidity in the immediate postpartum period American Journal Of Obstetrics And Gynecology 2018, 218: s198-s199. DOI: 10.1016/j.ajog.2017.10.251.
  • 14 Antepartum Fetal AssessmentPettker C, Campbell K. 14 Antepartum Fetal Assessment 2018, 145-157.e3. DOI: 10.1016/b978-0-323-40139-5.00014-0.
  • 18 Ambiguous GenitaliaPettker C. 18 Ambiguous Genitalia 2018, 72-74.e1. DOI: 10.1016/b978-0-323-44548-1.00018-8.
  • 454: Counsel confidently: Reliability of bedside EFW to predict survival at periviabilityKrenitsky N, Desai A, Johnson A, Pettker C. 454: Counsel confidently: Reliability of bedside EFW to predict survival at periviability American Journal Of Obstetrics And Gynecology 2018, 218: s274. DOI: 10.1016/j.ajog.2017.10.390.
  • Evaluating Effect of New Secure Smartphone Texting Tool in Obstetrics [7K]Feinberg J, Shaw S, Kashyap N, Campbell K, Pettker C. Evaluating Effect of New Secure Smartphone Texting Tool in Obstetrics [7K] Obstetrics And Gynecology 2017, 129: 113s. DOI: 10.1097/01.aog.0000514600.63312.7f.
  • Reducing Cesarean Delivery Surgical Site InfectionPritchard A, Donohue K, Hyland T, Raab C, Omara E, Pettker C. Reducing Cesarean Delivery Surgical Site Infection Obstetrics And Gynecology 2016, 127: 7s. DOI: 10.1097/01.aog.0000483636.97512.be.
  • Development of an obstetrical patient safety programPettker C, Funai E. Development of an obstetrical patient safety program 2015, 510-528. DOI: 10.1002/9781118327241.ch19.
  • Obstetrical emergenciesHan C, Pettker C. Obstetrical emergencies 2015, 225-257. DOI: 10.1002/9781118327241.ch11.
  • Suture Compared With Staple Skin Closure After Cesarean DeliveryMackeen A, Khalifeh A, Fleisher J, Vogell A, Han C, Sendecki J, Pettker C, Leiby B, Baxter J, Sfakianaki A, Berghella V. Suture Compared With Staple Skin Closure After Cesarean Delivery Obstetrical & Gynecological Survey 2014, 69: 549-550. DOI: 10.1097/01.ogx.0000455026.60201.61.
  • Patient Satisfaction and Cosmetic Outcome in a Randomized Study of Cesarean Skin ClosureMackeen A, Fleisher J, Khalifeh A, Pettker C, Berghella V. Patient Satisfaction and Cosmetic Outcome in a Randomized Study of Cesarean Skin Closure Obstetrics And Gynecology 2014, 123: 4s-5s. DOI: 10.1097/01.aog.0000447248.54066.04.
  • 457: Labor induction at 38 weeks versus expectant management of insulin-requiring diabetics in pregnancy: a cost effective analysisNayeri U, Tabbah S, Werner E, Pettker C, Landon M, Thung S. 457: Labor induction at 38 weeks versus expectant management of insulin-requiring diabetics in pregnancy: a cost effective analysis American Journal Of Obstetrics And Gynecology 2014, 210: s230. DOI: 10.1016/j.ajog.2013.10.490.
  • 368: Anti-inflammatory action of metformin in trophoblasts acts in an AMP-activated protein kinase (AMPK)-independent mannerPitruzzello M, Herrin M, Hardy J, Archabald K, Pettker C, Han C. 368: Anti-inflammatory action of metformin in trophoblasts acts in an AMP-activated protein kinase (AMPK)-independent manner American Journal Of Obstetrics And Gynecology 2014, 210: s187-s188. DOI: 10.1016/j.ajog.2013.10.401.
  • 733: Mixed bacteria generate a differential intra-amniotic inflammatory response compared to infections with a single microbial speciesDulay A, Buhimschi C, Shook L, Zhao G, Bahtiyar M, Pettker C, Sfakianaki A, Lipkind H, Abdel-Razeq S, Buhimschi I. 733: Mixed bacteria generate a differential intra-amniotic inflammatory response compared to infections with a single microbial species American Journal Of Obstetrics And Gynecology 2013, 208: s309. DOI: 10.1016/j.ajog.2012.10.071.
  • 836: Limiting exposure of a select group of fetuses to intra-amniotic infection (IAI) may improve short-term neonatal outcome in pregnancies complicated by PPROMArchabald K, Buhimschi I, Bahtiyar M, Dulay A, Abdel-Razeq S, Pettker C, Lipkind H, Hardy J, McCarthy M, Zhao G, Bhandari V, Buhimschi C. 836: Limiting exposure of a select group of fetuses to intra-amniotic infection (IAI) may improve short-term neonatal outcome in pregnancies complicated by PPROM American Journal Of Obstetrics And Gynecology 2013, 208: s349-s350. DOI: 10.1016/j.ajog.2012.10.174.
  • 337: Mode of delivery in the setting of prior shoulder dystocia: a cost-effectiveness analysisNayeri U, Werner E, Han C, Campbell K, Pettker C, Thung S. 337: Mode of delivery in the setting of prior shoulder dystocia: a cost-effectiveness analysis American Journal Of Obstetrics And Gynecology 2013, 208: s150. DOI: 10.1016/j.ajog.2012.10.502.
  • 541: Estimating blood loss: can an easily accessible visual aid significantly improve visual estimation?Zuckerwise L, Raab C, Buhimschi C, Pettker C, Lipkind H. 541: Estimating blood loss: can an easily accessible visual aid significantly improve visual estimation? American Journal Of Obstetrics And Gynecology 2013, 208: s232-s233. DOI: 10.1016/j.ajog.2012.10.707.
  • A Comprehensive Obstetrics Patient Safety Program Improves Safety Climate and CulturePettker C, Thung S, Raab C, Donohue K, Copel J, Lockwood C, Funai E. A Comprehensive Obstetrics Patient Safety Program Improves Safety Climate and Culture Obstetric Anesthesia Digest 2012, 32: 40. DOI: 10.1097/01.aoa.0000410802.93265.d8.
  • Thromboembolic DisordersPettker C, Lockwood C. Thromboembolic Disorders 2012, 121-130. DOI: 10.1002/9781119963783.ch16.
  • Patient SafetyPettker C. Patient Safety 2012, 439-444. DOI: 10.1002/9781119963783.ch53.
  • 584: Once-daily versus twice-daily antiretroviral dosing in HIV-infected pregnant womenHuynh T, Pettker C, Thung S, Magriples U, Duzyj C, Han C, Ali U. 584: Once-daily versus twice-daily antiretroviral dosing in HIV-infected pregnant women American Journal Of Obstetrics And Gynecology 2012, 206: s265. DOI: 10.1016/j.ajog.2011.10.602.
  • 51: Evidence for the presence of super-interleukin-6 (superIL-6) trans-signaling complex in amniotic fluid (AF) and its participation in the intraamniotic inflammatory response to infectionAbdel-Razeq S, Buhimschi I, Trotta K, Zhao G, Bahtiyar M, Pettker C, Buhimschi C. 51: Evidence for the presence of super-interleukin-6 (superIL-6) trans-signaling complex in amniotic fluid (AF) and its participation in the intraamniotic inflammatory response to infection American Journal Of Obstetrics And Gynecology 2012, 206: s32-s33. DOI: 10.1016/j.ajog.2011.10.077.
  • Chapter 13 Antepartum Fetal AssessmentPettker C, Campbell K. Chapter 13 Antepartum Fetal Assessment 2012, 129-139. DOI: 10.1016/b978-1-4377-0134-0.10013-7.
  • 570: Maternal mortality in New York City 1995-2003: disparities and risk factorsCampbell K, Goffman D, Sfakianaki A, Pettker C, Funai E, Savitz D, Lipkind H. 570: Maternal mortality in New York City 1995-2003: disparities and risk factors American Journal Of Obstetrics And Gynecology 2012, 206: s259-s260. DOI: 10.1016/j.ajog.2011.10.588.
  • 814: Evidence that endoglin and transforming growth factor-beta (TGFβ) participate in epithelial-to-mesenchymal transition (EMT) of extravillous trophoblasts in placenta accretaDuzyj C, Buhimschi I, Laky C, Cozzini G, Zhao G, Wehrum M, Pettker C, Abdel-Razeq S, Buhimschi C. 814: Evidence that endoglin and transforming growth factor-beta (TGFβ) participate in epithelial-to-mesenchymal transition (EMT) of extravillous trophoblasts in placenta accreta American Journal Of Obstetrics And Gynecology 2012, 206: s357. DOI: 10.1016/j.ajog.2011.10.832.
  • 250: Long term diabetes risk reduction necessary for gestational diabetes screening to be cost effectiveWerner E, Pettker C, Reel M, Zuckerwise L, Funai E, Thung S. 250: Long term diabetes risk reduction necessary for gestational diabetes screening to be cost effective American Journal Of Obstetrics And Gynecology 2012, 206: s122-s123. DOI: 10.1016/j.ajog.2011.10.268.
  • Chapter 43 Thromboembolic DisordersPettker C, Lockwood C. Chapter 43 Thromboembolic Disorders 2012, 980-993.e1. DOI: 10.1016/b978-1-4377-1935-2.00043-0.
  • 607: Administsration of lamivudine in the third trimester to reduce the risk of perinatal transmission of hepatitis B: a cost-effectiveness analysisAli U, Werner E, Han C, Pettker C, Funai E, Thung S. 607: Administsration of lamivudine in the third trimester to reduce the risk of perinatal transmission of hepatitis B: a cost-effectiveness analysis American Journal Of Obstetrics And Gynecology 2012, 206: s273. DOI: 10.1016/j.ajog.2011.10.625.
  • A Comprehensive Obstetrics Patient Safety Program Improves Safety Climate and CulturePettker C, Thung S, Raab C, Donohue K, Copel J, Lockwood C, Funai E. A Comprehensive Obstetrics Patient Safety Program Improves Safety Climate and Culture Obstetrical & Gynecological Survey 2011, 66: 346-347. DOI: 10.1097/ogx.0b013e31822c186f.
  • 333: Sonographic evaluation of myometrial thickness for prediction of a successful External Cephalic Version (ECV)Buhimschi C, Wehrum M, Sfakianaki A, Pettker C, Dulay A, Molaskey-Jones S, Thung S, Funai E, Buhimschi I, Bahtiyar M. 333: Sonographic evaluation of myometrial thickness for prediction of a successful External Cephalic Version (ECV) American Journal Of Obstetrics And Gynecology 2011, 204: s136-s137. DOI: 10.1016/j.ajog.2010.10.351.
  • 545: A comprehensive OB patient safety program reduces liability claimsPettker C, Thung S, Raab C, Copel J, Funai E. 545: A comprehensive OB patient safety program reduces liability claims American Journal Of Obstetrics And Gynecology 2011, 204: s218-s219. DOI: 10.1016/j.ajog.2010.10.565.
  • 670: Contributing indications to the increasing cesarean delivery rateBarber E, Lundsberg L, Raab C, Pettker C, Funai E, Illuzzi J. 670: Contributing indications to the increasing cesarean delivery rate American Journal Of Obstetrics And Gynecology 2011, 204: s264-s265. DOI: 10.1016/j.ajog.2010.10.690.
  • 280: Screening for gestational diabetes with a 1 hour glucose challenge test: is a 130mg/dL threshold more cost-effective than a 140mg/dL threshold?Reel M, Werner E, Pettker C, Funai E, Thung S. 280: Screening for gestational diabetes with a 1 hour glucose challenge test: is a 130mg/dL threshold more cost-effective than a 140mg/dL threshold? American Journal Of Obstetrics And Gynecology 2011, 204: s117-s118. DOI: 10.1016/j.ajog.2010.10.298.
  • 543: A comprehensive OB patient safety program improves safety climate and culturePettker C, Thung S, Raab C, Copel J, Funai E. 543: A comprehensive OB patient safety program improves safety climate and culture American Journal Of Obstetrics And Gynecology 2009, 201: s202-s203. DOI: 10.1016/j.ajog.2009.10.408.
  • Impact of a Comprehensive Patient Safety Strategy on Obstetric Adverse EventsPettker C, Thung S, Norwitz E, Buhimschi C, Raab C, Copel J, Kuczynski E, Lockwood C, Funai E. Impact of a Comprehensive Patient Safety Strategy on Obstetric Adverse Events Obstetric Anesthesia Digest 2009, 29: 215-216. DOI: 10.1097/01.aoa.0000362104.71945.98.
  • 460: Universal cervical length screening to prevent preterm birth: a cost-effectiveness analysisWerner E, Han C, Pettker C, Buhimschi C, Copel J, Funai E, Thung S. 460: Universal cervical length screening to prevent preterm birth: a cost-effectiveness analysis American Journal Of Obstetrics And Gynecology 2009, 201: s174. DOI: 10.1016/j.ajog.2009.10.626.
  • 193: Cord blood erythropoietin (EPO) levels are associated with an increased risk of intraventricular hemorrhage in the preterm neonateBhandari V, Buhimschi C, Han C, Lee S, Pettker C, Campbell K, Dulay A, Oliver E, Werner E, Buhimschi I. 193: Cord blood erythropoietin (EPO) levels are associated with an increased risk of intraventricular hemorrhage in the preterm neonate American Journal Of Obstetrics And Gynecology 2009, 201: s84. DOI: 10.1016/j.ajog.2009.10.208.
  • 723: Universal antenatal screening for spinal muscular atrophy (SMA): a cost-utility analysisHan C, Werner E, Pettker C, Norwitz E, Funai E, Thung S. 723: Universal antenatal screening for spinal muscular atrophy (SMA): a cost-utility analysis American Journal Of Obstetrics And Gynecology 2009, 201: s261. DOI: 10.1016/j.ajog.2009.10.740.
  • 652: Fetal host response to gram negative bacteria involves the novel Toll-like receptor-4 (TLR4) chaperone protein, soluble myeloid differentiation factor (SMD2)Dulay A, Buhimschi C, Zhao G, Oliver E, Lee S, Lee S, Han C, Pettker C, Buhimschi I. 652: Fetal host response to gram negative bacteria involves the novel Toll-like receptor-4 (TLR4) chaperone protein, soluble myeloid differentiation factor (SMD2) American Journal Of Obstetrics And Gynecology 2009, 201: s237. DOI: 10.1016/j.ajog.2009.10.517.
  • Predicting neonatal acidemia by computer analysis: Costa et alPettker C, Thung S, Dulay A, Han C, Ali U. Predicting neonatal acidemia by computer analysis: Costa et al American Journal Of Obstetrics And Gynecology 2009, 201: 543-544. DOI: 10.1016/j.ajog.2009.08.006.
  • Transcervical Foley Catheter With and Without Oxytocin for Cervical Ripening: A Randomized Controlled TrialPettker C, Pocock S, Smok D, Lee S, Devine P. Transcervical Foley Catheter With and Without Oxytocin for Cervical Ripening: A Randomized Controlled Trial Obstetric Anesthesia Digest 2009, 29: 33-34. DOI: 10.1097/01.aoa.0000344698.57807.3d.
  • 379: Management of twin pregnancies at term: What is the optimal gestational age at which all twin pregnancies should be delivered?Wehrum M, Bahtiyar M, Pettker C, Buhimschi C, Funai E, Thung S. 379: Management of twin pregnancies at term: What is the optimal gestational age at which all twin pregnancies should be delivered? American Journal Of Obstetrics And Gynecology 2008, 199: s115. DOI: 10.1016/j.ajog.2008.09.407.
  • 449: Amniotic fluid (AF) soluble toll-like receptor (TLR)-2 has functional ability to modulate the intensity of an intra-amniotic innate inflammatory response elicited by gram positive bacteriaDulay A, Zhao G, Lee S, Abdel-Razeq S, Bahtiyar M, Pettker C, Buhimschi C, Buhimschi I. 449: Amniotic fluid (AF) soluble toll-like receptor (TLR)-2 has functional ability to modulate the intensity of an intra-amniotic innate inflammatory response elicited by gram positive bacteria American Journal Of Obstetrics And Gynecology 2008, 199: s134. DOI: 10.1016/j.ajog.2008.09.478.
  • 768: The role of urinary endoglin in diagnosing severe preeclampsia: A prospective comparison with soluble fms-like tyrosine kinase (sFlt-1) to placental growth factor (PlGF) ratioBuhimschi C, Baumbusch M, Dulay A, Lee S, Wehrum M, Zhao G, Pettker C, Bahtiyar M, Funai E, Buhimschi I. 768: The role of urinary endoglin in diagnosing severe preeclampsia: A prospective comparison with soluble fms-like tyrosine kinase (sFlt-1) to placental growth factor (PlGF) ratio American Journal Of Obstetrics And Gynecology 2008, 199: s218. DOI: 10.1016/j.ajog.2008.09.799.
  • 6: Comprehensive proteomic mapping of cord blood to identify novel biomarkers and functional protein networks characteristic of early onset neonatal sepsis (EONS)Buhimschi C, Bhandari V, Dulay A, Lee S, Zhao G, Pettker C, Abdel-Razeq S, Thung S, Han Y, Buhimschi I. 6: Comprehensive proteomic mapping of cord blood to identify novel biomarkers and functional protein networks characteristic of early onset neonatal sepsis (EONS) American Journal Of Obstetrics And Gynecology 2008, 199: s3. DOI: 10.1016/j.ajog.2008.09.032.
  • 694: Is lowering the diagnostic threshold for gestational diabetes (GDM) cost-effective? Implications from the hyperglycemia and adverse pregnancy outcomes (HAPO) trialLee S, Pettker C, Funai E, Norwitz E, Thung S. 694: Is lowering the diagnostic threshold for gestational diabetes (GDM) cost-effective? Implications from the hyperglycemia and adverse pregnancy outcomes (HAPO) trial American Journal Of Obstetrics And Gynecology 2008, 199: s199. DOI: 10.1016/j.ajog.2008.09.725.
  • 502: Antimicrobial properties of the amniotic fluid (AF): A growth curve analysis of E. coliPettker C, Buhimschi C, Dulay A, Zhao G, Lee S, Thung S, Buhimschi I. 502: Antimicrobial properties of the amniotic fluid (AF): A growth curve analysis of E. coli American Journal Of Obstetrics And Gynecology 2008, 199: s148. DOI: 10.1016/j.ajog.2008.09.531.
  • Thromboembolic Disease: Diagnosis and Treatment During PregnancyPettker C, Lockwood C. Thromboembolic Disease: Diagnosis and Treatment During Pregnancy The Global Library Of Women's Medicine 2008 DOI: 10.3843/glowm.10165.
  • 137: Ultrasonographic evaluation of cervical length (CL) and myometrial thickness (MT) as predictors of latency interval in PPROMPettker C, Azpurua H, Bahtiyar M, Sfakianaki A, Thung S, Buhimschi I, Buhimschi C. 137: Ultrasonographic evaluation of cervical length (CL) and myometrial thickness (MT) as predictors of latency interval in PPROM American Journal Of Obstetrics And Gynecology 2007, 197: s51. DOI: 10.1016/j.ajog.2007.10.149.
  • 465: Fractional excretion of tumor necrosis factor-alpha (TNF) in women with severe preeclampsiaCackovic M, Buhimschi I, Zhao G, Luo G, Abdel-Razeq S, Dulay A, Rosenberg V, Bahtiyar M, Thung S, Lipkind H, Pettker C, Norwitz E, Funai E, Buhimschi C. 465: Fractional excretion of tumor necrosis factor-alpha (TNF) in women with severe preeclampsia American Journal Of Obstetrics And Gynecology 2007, 197: s136. DOI: 10.1016/j.ajog.2007.10.484.
  • 199: Early onset neonatal sepsis (EONS): Accompanied by an increased interleukin-6 (IL-6) cytokine index, linked to histological chorioamnionitisBuhimschi C, Thung S, Bahtiyar M, Rosenberg V, Dulay A, Abdel-Razeq S, Pettker C, Luo G, Zhao G, Sfakianaki A, Lipkind H, Funai E, Bhandari V, Buhimschi I. 199: Early onset neonatal sepsis (EONS): Accompanied by an increased interleukin-6 (IL-6) cytokine index, linked to histological chorioamnionitis American Journal Of Obstetrics And Gynecology 2007, 197: s67. DOI: 10.1016/j.ajog.2007.10.212.
  • 50: Nucleated red blood cells (NRBC) are a direct response to mediators of inflammation in newborns with early onset neonatal sepsis (EONS)Dulay A, buhimschi I, Zhao G, Luo G, Abdel-Razeq S, Cackovic M, Rosenberg V, Pettker C, Thung S, Bahtiyar M, Bhandari V, Buhimschi C. 50: Nucleated red blood cells (NRBC) are a direct response to mediators of inflammation in newborns with early onset neonatal sepsis (EONS) American Journal Of Obstetrics And Gynecology 2007, 197: s22. DOI: 10.1016/j.ajog.2007.10.056.
  • 81: Impact of a comprehensive strategy to reduce obstetric adverse eventsFunai E, Pettker C, Thung S, Raab C, Norwitz E, Buhimschi C, Copel J, Lockwood C. 81: Impact of a comprehensive strategy to reduce obstetric adverse events American Journal Of Obstetrics And Gynecology 2007, 197: s36. DOI: 10.1016/j.ajog.2007.10.091.
  • 194: A role for the amniotic fluid inhibin (INH) — activin (ACT) system in preterm premature rupture of the membranes and intra-amniotic infectionRosenberg V, Buhimschi C, Dulay A, Oliver E, Jing S, Pettker C, Abdel-Razeq S, Cackovic M, Luo G, Buhimschi I. 194: A role for the amniotic fluid inhibin (INH) — activin (ACT) system in preterm premature rupture of the membranes and intra-amniotic infection American Journal Of Obstetrics And Gynecology 2007, 197: s65. DOI: 10.1016/j.ajog.2007.10.207.
  • 78: Interleukin-1B (IL-1B) but not thrombin upregulates vascular endothelial growth factor (VEGF) production by human cytotrophoblast-derived HTR-8/SV neo cells: Implications for infection-related preterm birth and abruptionHodgson E, Snegovskikh V, Luo G, Dulay A, Pettker C, Lee S, Guller S, Norwitz E. 78: Interleukin-1B (IL-1B) but not thrombin upregulates vascular endothelial growth factor (VEGF) production by human cytotrophoblast-derived HTR-8/SV neo cells: Implications for infection-related preterm birth and abruption American Journal Of Obstetrics And Gynecology 2007, 197: s34. DOI: 10.1016/j.ajog.2007.10.087.
  • 355: Screening for gestational diabetes: Is a 130mg/dL or 140mg/dL glucose challenge test threshold more cost-effective?Thung S, Pettker C, Funai E. 355: Screening for gestational diabetes: Is a 130mg/dL or 140mg/dL glucose challenge test threshold more cost-effective? American Journal Of Obstetrics And Gynecology 2007, 197: s109. DOI: 10.1016/j.ajog.2007.10.372.
  • Pathophysiology and Diagnosis of Thromboembolic Disorders in PregnancyPettker C, Lockwood C. Pathophysiology and Diagnosis of Thromboembolic Disorders in Pregnancy 2007, 133-142. DOI: 10.1002/9780470691878.ch16.
  • Thromboembolic Disorders of PregnancyPaidas M, Pettker C, Lockwood C. Thromboembolic Disorders of Pregnancy 2007, 825-848. DOI: 10.1002/9780470753293.ch47.
  • Thromboembolic Disorders of PregnancyPaidas M, Pettker C, Lockwood C. Thromboembolic Disorders of Pregnancy 2007, 341-349. DOI: 10.1002/9780470753323.ch44.
  • CHAPTER 41 Thromboembolic DisordersPettker C, Lockwood C. CHAPTER 41 Thromboembolic Disorders 2007, 1064-1079. DOI: 10.1016/b978-0-443-06930-7.50043-8.
  • Fetal heart rate monitoring patterns (FHR-MP) to predict early-onset neonatal sepsis in utero in pregnancies complicated by intra-amniotic infection/inflammationBuhimschi C, Abdel-Razeq S, Pettker C, Cackovic M, Bahtiyar M, Norwitz E, Bhandari V, Buhimschi I. Fetal heart rate monitoring patterns (FHR-MP) to predict early-onset neonatal sepsis in utero in pregnancies complicated by intra-amniotic infection/inflammation American Journal Of Obstetrics And Gynecology 2006, 195: s224. DOI: 10.1016/j.ajog.2006.10.814.
  • Intra-amniotic inflammation activates the fetal hypothalamic-pituitary adrenal axis in utero as identified by 3D ultrasound assessment of fetal adrenal gland volumeBuhimschi C, Turan O, Funai E, Turan S, Copel J, Bahtiyar M, Pettker C, Norwitz E, Buhimschi I. Intra-amniotic inflammation activates the fetal hypothalamic-pituitary adrenal axis in utero as identified by 3D ultrasound assessment of fetal adrenal gland volume American Journal Of Obstetrics And Gynecology 2006, 195: s44. DOI: 10.1016/j.ajog.2006.10.121.
  • Lactate dehydrogenase (LDH) isoform activity in the vaginal “pool” - a marker of intra-amniotic infection in women with preterm premature rupture of membranesMagloire L, Buhimschi C, Pettker C, Abdel-Razeq S, Rosenberg V, Cackovic M, Bahtiyar M, Buhimschi I. Lactate dehydrogenase (LDH) isoform activity in the vaginal “pool” - a marker of intra-amniotic infection in women with preterm premature rupture of membranes American Journal Of Obstetrics And Gynecology 2006, 195: s64. DOI: 10.1016/j.ajog.2006.10.199.
  • Ultrasound evaluation of uterine incision healing after cesarean delivery – a randomized controlled study of one-versus two-layer closureHamar B, Saber S, Cackovic M, Magloire L, Pettker C, Abdel-Razeq S, Rosenberg V, Buhimschi I, Buhimschi C. Ultrasound evaluation of uterine incision healing after cesarean delivery – a randomized controlled study of one-versus two-layer closure American Journal Of Obstetrics And Gynecology 2006, 195: s57. DOI: 10.1016/j.ajog.2006.10.171.
  • Preconception multivitamin or folic acid consumption and pregnancy outcome: A population-based screening studyGraham G, Malone F, Pettker C, Sullivan L, Ball R, Luthy D, Comstock C, Hankins G, Eddleman K, Gross S, Dugoff L, Craigo S, Timor I, Carr S, Wolfe H, D'alton M. Preconception multivitamin or folic acid consumption and pregnancy outcome: A population-based screening study American Journal Of Obstetrics And Gynecology 2006, 195: s218. DOI: 10.1016/j.ajog.2006.10.794.
  • Proteomic analysis of the human amniotic fluid (AF) to predict histological chorioamnionitis (HCA) in uteroBuhimschi I, Pettker C, Magloire L, Thung S, Zhao G, Salafia C, Buhimschi C. Proteomic analysis of the human amniotic fluid (AF) to predict histological chorioamnionitis (HCA) in utero American Journal Of Obstetrics And Gynecology 2006, 195: s9. DOI: 10.1016/j.ajog.2006.10.024.
  • A prospective, randomized trial of transcervical foley catheter with or without oxytocin for preinduction cervical ripeningPettker C, Pocock S, Smok D, Devine P. A prospective, randomized trial of transcervical foley catheter with or without oxytocin for preinduction cervical ripening American Journal Of Obstetrics And Gynecology 2006, 195: s27. DOI: 10.1016/j.ajog.2006.10.070.
  • OP06.15: Estimating fetal hematocrit by middle cerebral artery peak systolic flow velocityBahtiyar M, Pettker C, Copel J. OP06.15: Estimating fetal hematocrit by middle cerebral artery peak systolic flow velocity Ultrasound In Obstetrics And Gynecology 2006, 28: 456-457. DOI: 10.1002/uog.3193.
  • A low vaginal “POOL” amniotic fluid (AF) glucose measurement is a predictive but not a sensitive marker for infection in women with PPROMBuhimschi C, Sfakianaki A, Hamar B, Pettker C, Bahtiyar M, Funai E, Norwitz E, Copel J, Lockwood C, Buhimschi I. A low vaginal “POOL” amniotic fluid (AF) glucose measurement is a predictive but not a sensitive marker for infection in women with PPROM American Journal Of Obstetrics And Gynecology 2005, 193: s186. DOI: 10.1016/j.ajog.2005.10.753.
  • Detection of intraamniotic inflammation/infection by proteomic profiling. Prospective comparison with rapid diagnostic tests (glucose, WBC, LDH, Gram stain), IL-6 and MMP-8Buhimschi C, Hamar B, Bahtiyar M, Zhao G, Sfakianaki A, Pettker C, Magloire L, Norwitz E, Funai E, Paidas M, Weiner C, Copel J, Lockwood C, Buhimschi I. Detection of intraamniotic inflammation/infection by proteomic profiling. Prospective comparison with rapid diagnostic tests (glucose, WBC, LDH, Gram stain), IL-6 and MMP-8 American Journal Of Obstetrics And Gynecology 2005, 193: s33. DOI: 10.1016/j.ajog.2005.10.085.
  • Evidence for participation of rage (receptor for advanced glycation end products), soluble rage (sRAGE) and S100A12 proteins, in control of the inflammatory response of amniotic cavity during pregnancyBuhimschi I, Zhao G, Pettker C, Bahtiyar M, Magloire L, Buhimschi C. Evidence for participation of rage (receptor for advanced glycation end products), soluble rage (sRAGE) and S100A12 proteins, in control of the inflammatory response of amniotic cavity during pregnancy American Journal Of Obstetrics And Gynecology 2005, 193: s9. DOI: 10.1016/j.ajog.2005.10.018.
  • Longitudinal ultrasonographic evaluation of myometrial thickness (MT) in twin pregnanciesSfakianaki A, Pettker C, Magloire L, Hamar B, Buhimschi I, Copel J, Buhimschi C. Longitudinal ultrasonographic evaluation of myometrial thickness (MT) in twin pregnancies American Journal Of Obstetrics And Gynecology 2005, 193: s156. DOI: 10.1016/j.ajog.2005.10.627.
  • Urinary inhibin a (INH) and activin (ACT) in hypertensive disorders during pregnancyHamar B, Buhimschi I, Sfakianaki A, Pettker C, Magloire L, Funai E, Copel J, Buhimschi C. Urinary inhibin a (INH) and activin (ACT) in hypertensive disorders during pregnancy American Journal Of Obstetrics And Gynecology 2005, 193: s73. DOI: 10.1016/j.ajog.2005.10.262.
  • Profiling of lactate dehydrogenase (LDH) isoform activity in women with intra-amniotic infection/inflammation (IAI/I)Magloire L, Buhimschi C, Pettker C, Sfakianaki A, Hamar B, Bhandari V, Buhimschi I. Profiling of lactate dehydrogenase (LDH) isoform activity in women with intra-amniotic infection/inflammation (IAI/I) American Journal Of Obstetrics And Gynecology 2005, 193: s6. DOI: 10.1016/j.ajog.2005.10.016.
  • The value of placental microbial studies to predict the results of amniotic fluid (AF) culturesPettker C, Magloire L, Sfakianaki A, Hamar B, Buhimschi I, Buhimschi C. The value of placental microbial studies to predict the results of amniotic fluid (AF) cultures American Journal Of Obstetrics And Gynecology 2005, 193: s17. DOI: 10.1016/j.ajog.2005.10.039.
  • Mass spectrometry (MS) - A novel approach in deciphering the origin and duration of intra-amniotic bleedingBuhimschi I, Buhimschi C, Zhao G, Pettker C, Weiner C. Mass spectrometry (MS) - A novel approach in deciphering the origin and duration of intra-amniotic bleeding American Journal Of Obstetrics And Gynecology 2005, 193: s107. DOI: 10.1016/j.ajog.2005.10.369.

Clinical Trials

ConditionsStudy Title
Pregnancy, Childbirth and the Puerperium; Pain ControlPrescription After Cesarean Trial (PACT)
Pregnancy, Childbirth and the PuerperiumA Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix (PROSPECT)
Pregnancy, Childbirth and the PuerperiumA Randomized Trial of Pessary in Singleton Pregnancies With a Short Cervix (TOPS)
Pregnancy, Childbirth and the Puerperium; HypertensionChronic Hypertension and Pregnancy (CHAP) Project (CHAP)