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Audrey Leasure, MD, MHS

Hospital Resident

Research & Publications
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Selected Publications

Thyroid disorders associated with lichen sclerosus: a case–control study in the All of Us Research ProgramFan R, Leasure AC, Maisha FI, Cohen JM, Little AJ. Thyroid disorders associated with lichen sclerosus: a case–control study in the All of Us Research Program. British Journal Of Dermatology 2022, 187: 797-799. PMID: 35661997, PMCID: PMC9633359, DOI: 10.1111/bjd.21702.
Alcohol use disorder among adults with atopic dermatitis: A case-control study in the All of Us research programFan R, Leasure AC, Damsky W, Cohen JM. Alcohol use disorder among adults with atopic dermatitis: A case-control study in the All of Us research program. Journal Of The American Academy Of Dermatology 2022, 87: 1378-1380. PMID: 36152694, DOI: 10.1016/j.jaad.2022.09.015.
Association of Chronic Kidney Disease With Risk of Intracerebral HemorrhageVanent KN, Leasure AC, Acosta JN, Kuohn LR, Woo D, Murthy SB, Kamel H, Messé SR, Mullen MT, Cohen JB, Cohen DL, Townsend RR, Petersen NH, Sansing LH, Gill TM, Sheth KN, Falcone GJ. Association of Chronic Kidney Disease With Risk of Intracerebral Hemorrhage. JAMA Neurology 2022, 79: 911-918. PMID: 35969388, PMCID: PMC9379821, DOI: 10.1001/jamaneurol.2022.2299.
Association of autoimmune comorbidities with lichen planus: A United States-based case-control study in the All of Us research programFan R, Leasure AC, Cohen JM. Association of autoimmune comorbidities with lichen planus: A United States-based case-control study in the All of Us research program. Journal Of The American Academy Of Dermatology 2022, 87: 1451-1453. PMID: 35931217, DOI: 10.1016/j.jaad.2022.07.037.
Depression and Anxiety in Patients With Lichen SclerosusFan R, Leasure AC, Maisha FI, Little AJ, Cohen JM. Depression and Anxiety in Patients With Lichen Sclerosus. JAMA Dermatology 2022, 158: 953-954. PMID: 35704313, PMCID: PMC9201736, DOI: 10.1001/jamadermatol.2022.1964.
Genetically‐Proxied Levels of Vitamin D and Risk of Intracerebral HemorrhageSzejko N, Acosta JN, Both CP, Leasure A, Matouk C, Sansing L, Gill TM, Hongyu Z, Sheth K, Falcone GJ. Genetically‐Proxied Levels of Vitamin D and Risk of Intracerebral Hemorrhage. Journal Of The American Heart Association 2022, 11: e024141. PMID: 35730641, PMCID: PMC9333362, DOI: 10.1161/jaha.121.024141.
Analysis of Clinical Traits Associated With Cardiovascular Health, Genomic Profiles, and Neuroimaging Markers of Brain Health in Adults Without Stroke or DementiaAcosta JN, Both CP, Rivier C, Szejko N, Leasure AC, Gill TM, Payabvash S, Sheth KN, Falcone GJ. Analysis of Clinical Traits Associated With Cardiovascular Health, Genomic Profiles, and Neuroimaging Markers of Brain Health in Adults Without Stroke or Dementia. JAMA Network Open 2022, 5: e2215328. PMID: 35622359, PMCID: PMC9142873, DOI: 10.1001/jamanetworkopen.2022.15328.
Association of atopic dermatitis with attention-deficit hyperactivity disorder among US adults in the “All of Us” research program: A case-control studyFan R, Leasure AC, Damsky W, Cohen JM. Association of atopic dermatitis with attention-deficit hyperactivity disorder among US adults in the “All of Us” research program: A case-control study. Journal Of The American Academy Of Dermatology 2022, 87: 691-692. PMID: 35283246, DOI: 10.1016/j.jaad.2022.03.014.
Prevalence of eczema among adults in the United States: a cross-sectional study in the All of Us research programLeasure AC, Cohen JM. Prevalence of eczema among adults in the United States: a cross-sectional study in the All of Us research program. Archives Of Dermatological Research 2022, 315: 999-1001. PMID: 35147780, DOI: 10.1007/s00403-022-02328-0.
The authors replyAcosta JN, Leasure AC, Sheth KN, Falcone GJ. The authors reply. Critical Care Medicine 2022, 50: e215-e216. PMID: 35100204, PMCID: PMC8842829, DOI: 10.1097/ccm.0000000000005388.
Facial hyperpigmentation and crusted papules on the hands.Leasure AC, Turner N, Lim I. Facial hyperpigmentation and crusted papules on the hands. JAAD Case Reports 2022, 20: 23-25. PMID: 35036499, PMCID: PMC8753054, DOI: 10.1016/j.jdcr.2021.09.043.
Association between atopic dermatitis and COVID-19 infection: A case-control study in the All of Us research programFan R, Leasure AC, Damsky W, Cohen JM. Association between atopic dermatitis and COVID-19 infection: A case-control study in the All of Us research program. JAAD International 2021, 6: 77-81. PMID: 34977817, PMCID: PMC8712258, DOI: 10.1016/j.jdin.2021.12.007.
Prevalence of lichen planus in the United States: A cross-sectional study of the All of Us research programLeasure AC, Cohen JM. Prevalence of lichen planus in the United States: A cross-sectional study of the All of Us research program. Journal Of The American Academy Of Dermatology 2021, 87: 686-687. PMID: 34920026, DOI: 10.1016/j.jaad.2021.12.013.
Genetically Determined Low‐Density Lipoprotein Cholesterol and Risk of Subarachnoid HemorrhageAcosta JN, Both CP, Szejko N, Leasure AC, Abdelhakim S, Torres‐Lopez V, Brown SC, Matouk CC, Gunel M, Sheth KN, Falcone GJ. Genetically Determined Low‐Density Lipoprotein Cholesterol and Risk of Subarachnoid Hemorrhage. Annals Of Neurology 2021, 91: 145-149. PMID: 34709661, DOI: 10.1002/ana.26250.
Association of lichen planus with cardiovascular disease: A combined analysis of the UK Biobank and All of Us StudyLeasure AC, Acosta JN, Sansing LH, Sheth KN, Cohen JM, Falcone GJ. Association of lichen planus with cardiovascular disease: A combined analysis of the UK Biobank and All of Us Study. Journal Of The American Academy Of Dermatology 2021, 87: 454-456. PMID: 34562549, DOI: 10.1016/j.jaad.2021.09.030.
Cardiovascular Health Disparities in Racial and Other Underrepresented Groups: Initial Results From the All of Us Research ProgramAcosta JN, Leasure AC, Both CP, Szejko N, Brown S, Torres‐Lopez V, Abdelhakim S, Schindler J, Petersen N, Sansing L, Gill TM, Sheth KN, Falcone GJ. Cardiovascular Health Disparities in Racial and Other Underrepresented Groups: Initial Results From the All of Us Research Program. Journal Of The American Heart Association 2021, 10: e021724. PMID: 34431358, PMCID: PMC8649271, DOI: 10.1161/jaha.121.021724.
Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhageMazurek MH, Cahn BA, Yuen MM, Prabhat AM, Chavva IR, Shah JT, Crawford AL, Welch EB, Rothberg J, Sacolick L, Poole M, Wira C, Matouk CC, Ward A, Timario N, Leasure A, Beekman R, Peng TJ, Witsch J, Antonios JP, Falcone GJ, Gobeske KT, Petersen N, Schindler J, Sansing L, Gilmore EJ, Hwang DY, Kim JA, Malhotra A, Sze G, Rosen MS, Kimberly WT, Sheth KN. Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage. Nature Communications 2021, 12: 5119. PMID: 34433813, PMCID: PMC8387402, DOI: 10.1038/s41467-021-25441-6.
Intracerebral Hemorrhage in COVID-19 InfectionAtillasoy J, Leasure AC, Sheth KN. Intracerebral Hemorrhage in COVID-19 Infection. World Neurosurgery 2021, 153: 142-143. PMID: 34420767, PMCID: PMC8376376, DOI: 10.1016/j.wneu.2021.06.102.
Prevalence of granuloma annulare in the United States: a cross‐sectional study in the All of Us Research ProgramLeasure AC, Damsky W, Cohen JM. Prevalence of granuloma annulare in the United States: a cross‐sectional study in the All of Us Research Program. International Journal Of Dermatology 2021, 61: e301-e302. PMID: 34363612, PMCID: PMC8818807, DOI: 10.1111/ijd.15832.
Comorbidities associated with granuloma annulare: A case-control study in the All of Us research programLeasure AC, Damsky W, Cohen JM. Comorbidities associated with granuloma annulare: A case-control study in the All of Us research program. Journal Of The American Academy Of Dermatology 2021, 87: 197-199. PMID: 34333076, PMCID: PMC8799765, DOI: 10.1016/j.jaad.2021.07.033.
Stroke Disparities Among Nonracial Minorities in the All of Us Research ProgramLeasure AC, Acosta JN, Both C, Szejko N, Brown SC, Sheth KN, Falcone GJ. Stroke Disparities Among Nonracial Minorities in the All of Us Research Program. Stroke 2021, 52: e488-e490. PMID: 34139858, PMCID: PMC8316290, DOI: 10.1161/strokeaha.121.034903.
Intracerebral Hemorrhage in Patients With COVID-19Leasure AC, Khan YM, Iyer R, Elkind MSV, Sansing LH, Falcone GJ, Sheth KN. Intracerebral Hemorrhage in Patients With COVID-19. Stroke 2021, 52: e321-e323. PMID: 34082576, PMCID: PMC8238884, DOI: 10.1161/strokeaha.121.034215.
Obstructive Sleep Apnea as a Risk Factor for Intracerebral HemorrhageGeer JH, Falcone GJ, Vanent KN, Leasure AC, Woo D, Molano JR, Sansing LH, Langefeld CD, Pisani MA, Yaggi HK, Sheth KN. Obstructive Sleep Apnea as a Risk Factor for Intracerebral Hemorrhage. Stroke 2021, 52: 1835-1838. PMID: 33827242, PMCID: PMC8085039, DOI: 10.1161/strokeaha.120.033342.
Association of Serum IL-6 (Interleukin 6) With Functional Outcome After Intracerebral HemorrhageLeasure AC, Kuohn LR, Vanent KN, Bevers MB, Kimberly WT, Steiner T, Mayer SA, Matouk CC, Sansing LH, Falcone GJ, Sheth KN. Association of Serum IL-6 (Interleukin 6) With Functional Outcome After Intracerebral Hemorrhage. Stroke 2021, 52: 1733-1740. PMID: 33682454, PMCID: PMC8085132, DOI: 10.1161/strokeaha.120.032888.
Admission Hemoglobin Levels Are Associated With Functional Outcome in Spontaneous Intracerebral HemorrhageAcosta JN, Leasure AC, Kuohn LR, Both CP, Petersen NH, Sansing LH, Matouk CC, Testai F, Langefeld CD, Woo D, Kamel H, Murthy SB, Qureshi A, Mayer SA, Sheth KN, Falcone GJ. Admission Hemoglobin Levels Are Associated With Functional Outcome in Spontaneous Intracerebral Hemorrhage. Critical Care Medicine 2021, 49: 828-837. PMID: 33591003, PMCID: PMC8611893, DOI: 10.1097/ccm.0000000000004891.
Intracerebral Hemorrhage with Intraventricular Extension Associated with Loss of Consciousness at Symptom OnsetWitsch J, Falcone GJ, Leasure AC, Matouk C, Endres M, Sansing L, Woo D, Sheth KN. Intracerebral Hemorrhage with Intraventricular Extension Associated with Loss of Consciousness at Symptom Onset. Neurocritical Care 2021, 35: 418-427. PMID: 33479920, PMCID: PMC8578176, DOI: 10.1007/s12028-020-01180-2.
Author response: Racial/ethnic disparities in the risk of intracerebral hemorrhage recurrence.Leasure AC, Sheth KN. Author response: Racial/ethnic disparities in the risk of intracerebral hemorrhage recurrence. Neurology 2020, 95: 660. PMID: 33020203, DOI: 10.1212/wnl.0000000000010665.
Cause of death in spontaneous intracerebral hemorrhage survivors: Multistate longitudinal study.Kuohn LR, Leasure AC, Acosta JN, Vanent K, Murthy SB, Kamel H, Matouk CC, Sansing LH, Falcone GJ, Sheth KN. Cause of death in spontaneous intracerebral hemorrhage survivors: Multistate longitudinal study. Neurology 2020, 95: e2736-e2745. PMID: 32917797, PMCID: PMC7734723, DOI: 10.1212/wnl.0000000000010736.
Genetically Elevated LDL Associates with Lower Risk of Intracerebral HemorrhageFalcone GJ, Kirsch E, Acosta JN, Noche RB, Leasure A, Marini S, Chung J, Selim M, Meschia JF, Brown DL, Worrall BB, Tirschwell DL, Jagiella JM, Schmidt H, Jimenez‐Conde J, Fernandez‐Cadenas I, Lindgren A, Slowik A, Gill D, Holmes M, Phuah C, Petersen NH, Matouk CN, Gunel M, Sansing L, Bennett D, Chen Z, Sun LL, Clarke R, Walters RG, Gill TM, Biffi A, Kathiresan S, Langefeld CD, Woo D, Rosand J, Sheth KN, Anderson CD, Consortium F. Genetically Elevated LDL Associates with Lower Risk of Intracerebral Hemorrhage. Annals Of Neurology 2020, 88: 56-66. PMID: 32277781, PMCID: PMC7523882, DOI: 10.1002/ana.25740.
Race/ethnicity influences outcomes in young adults with supratentorial intracerebral hemorrhage.Miyares LC, Falcone GJ, Leasure A, Adeoye O, Shi FD, Kittner SJ, Langefeld C, Vagal A, Sheth KN, Woo D. Race/ethnicity influences outcomes in young adults with supratentorial intracerebral hemorrhage. Neurology 2020, 94: e1271-e1280. PMID: 31969467, PMCID: PMC7274930, DOI: 10.1212/wnl.0000000000008930.
Racial/ethnic disparities in the risk of intracerebral hemorrhage recurrence.Leasure AC, King ZA, Torres-Lopez V, Murthy SB, Kamel H, Shoamanesh A, Al-Shahi Salman R, Rosand J, Ziai WC, Hanley DF, Woo D, Matouk CC, Sansing LH, Falcone GJ, Sheth KN. Racial/ethnic disparities in the risk of intracerebral hemorrhage recurrence. Neurology 2019, 94: e314-e322. PMID: 31831597, PMCID: PMC7108806, DOI: 10.1212/wnl.0000000000008737.
Perihematomal Edema After Intracerebral Hemorrhage in Patients With Active MalignancyGusdon AM, Nyquist PA, Torres-Lopez VM, Leasure AC, Falcone GJ, Sheth KN, Sansing LH, Hanley DF, Malani R. Perihematomal Edema After Intracerebral Hemorrhage in Patients With Active Malignancy. Stroke 2019, 51: 129-136. PMID: 31744426, PMCID: PMC7048624, DOI: 10.1161/strokeaha.119.027085.
Association of Surgical Hematoma Evacuation vs Conservative Treatment With Functional Outcome in Patients With Cerebellar Intracerebral HemorrhageKuramatsu JB, Biffi A, Gerner ST, Sembill JA, Sprügel MI, Leasure A, Sansing L, Matouk C, Falcone GJ, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker J, Rizos T, Volkmann J, Müllges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Rahmig J, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Claßen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Günther A, Hamann GF, Hagen M, Roeder SS, Lücking H, Dörfler A, Testai FD, Woo D, Schwab S, Sheth KN, Huttner HB. Association of Surgical Hematoma Evacuation vs Conservative Treatment With Functional Outcome in Patients With Cerebellar Intracerebral Hemorrhage. JAMA 2019, 322: 1392-1403. PMID: 31593272, PMCID: PMC6784768, DOI: 10.1001/jama.2019.13014.
Resuming Anticoagulation After Cerebral Intraparenchymal HemorrhageLeasure AC, Sheth KN. Resuming Anticoagulation After Cerebral Intraparenchymal Hemorrhage. JAMA 2019, 322: 694-694. PMID: 31429890, DOI: 10.1001/jama.2019.8650.
Association of Intensive Blood Pressure Reduction With Risk of Hematoma Expansion in Patients With Deep Intracerebral HemorrhageLeasure AC, Qureshi AI, Murthy SB, Kamel H, Goldstein JN, Woo D, Ziai WC, Hanley DF, Salman R, Matouk CC, Sansing LH, Sheth KN, Falcone GJ. Association of Intensive Blood Pressure Reduction With Risk of Hematoma Expansion in Patients With Deep Intracerebral Hemorrhage. JAMA Neurology 2019, 76: 949-955. PMID: 31081862, PMCID: PMC6515816, DOI: 10.1001/jamaneurol.2019.1141.
Intensive Blood Pressure Reduction and Perihematomal Edema Expansion in Deep Intracerebral HemorrhageLeasure AC, Qureshi AI, Murthy SB, Kamel H, Goldstein JN, Walsh KB, Woo D, Shi FD, Huttner HB, Ziai WC, Hanley DF, Matouk CC, Sansing LH, Falcone GJ, Sheth KN. Intensive Blood Pressure Reduction and Perihematomal Edema Expansion in Deep Intracerebral Hemorrhage. Stroke 2019, 50: 2016-2022. PMID: 31272326, PMCID: PMC6646091, DOI: 10.1161/strokeaha.119.024838.
Identification and Validation of Hematoma Volume Cutoffs in Spontaneous, Supratentorial Deep Intracerebral HemorrhageLeasure AC, Sheth KN, Comeau M, Aldridge C, Worrall BB, Vashkevich A, Rosand J, Langefeld C, Moomaw CJ, Woo D, Falcone GJ. Identification and Validation of Hematoma Volume Cutoffs in Spontaneous, Supratentorial Deep Intracerebral Hemorrhage. Stroke 2019, 50: 2044-2049. PMID: 31238829, PMCID: PMC6646054, DOI: 10.1161/strokeaha.118.023851.
Cardioembolic Stroke Risk and Recovery After Anticoagulation-Related Intracerebral HemorrhageMurphy MP, Kuramatsu JB, Leasure A, Falcone GJ, Kamel H, Sansing LH, Kourkoulis C, Schwab K, Elm JJ, Gurol ME, Tran H, Greenberg SM, Viswanathan A, Anderson CD, Schwab S, Rosand J, Shi FD, Kittner SJ, Testai FD, Woo D, Langefeld CD, James ML, Koch S, Huttner HB, Biffi A, Sheth KN. Cardioembolic Stroke Risk and Recovery After Anticoagulation-Related Intracerebral Hemorrhage. Stroke 2018, 49: 2652-2658. PMID: 30355194, PMCID: PMC6211810, DOI: 10.1161/strokeaha.118.021799.
Publication and Dissemination of Results in Clinical Trials of NeurologySreekrishnan A, Mampre D, Ormseth C, Miyares L, Leasure A, Ross JS, Sheth KN. Publication and Dissemination of Results in Clinical Trials of Neurology. JAMA Neurology 2018, 75: 890-891. PMID: 29710083, PMCID: PMC6145765, DOI: 10.1001/jamaneurol.2018.0674.
Minority Patients are Less Likely to Undergo Withdrawal of Care After Spontaneous Intracerebral HemorrhageOrmseth CH, Falcone GJ, Jasak SD, Mampre DM, Leasure AC, Miyares LC, Hwang DY, James ML, Testai FD, Becker KJ, Tirschwell DL, Langefeld CD, Woo D, Sheth KN. Minority Patients are Less Likely to Undergo Withdrawal of Care After Spontaneous Intracerebral Hemorrhage. Neurocritical Care 2018, 29: 419-425. PMID: 29949003, PMCID: PMC6286261, DOI: 10.1007/s12028-018-0554-4.
Left Atrial Appendage Morphology and Embolic Stroke of Undetermined Source: A Cross-Sectional Multicenter Pilot StudyYaghi S, Chang AD, Hung P, Mac Grory B, Collins S, Gupta A, Reynolds J, Finn CB, Hemendinger M, Cutting SM, McTaggart RA, Jayaraman M, Leasure A, Sansing L, Panda N, Song C, Chu A, Merkler A, Gialdini G, Sheth KN, Kamel H, Elkind MSV, Greer D, Furie K, Atalay M. Left Atrial Appendage Morphology and Embolic Stroke of Undetermined Source: A Cross-Sectional Multicenter Pilot Study. Journal Of Stroke And Cerebrovascular Diseases 2018, 27: 1497-1501. PMID: 29398537, DOI: 10.1016/j.jstrokecerebrovasdis.2017.12.036.
Oral Anticoagulation and Functional Outcome after Intracerebral HemorrhageBiffi A, Kuramatsu JB, Leasure A, Kamel H, Kourkoulis C, Schwab K, Ayres AM, Elm J, Gurol ME, Greenberg SM, Viswanathan A, Anderson CD, Schwab S, Rosand J, Testai FD, Woo D, Huttner HB, Sheth KN. Oral Anticoagulation and Functional Outcome after Intracerebral Hemorrhage. Annals Of Neurology 2017, 82: 755-765. PMID: 29028130, PMCID: PMC5730065, DOI: 10.1002/ana.25079.
Functional Improvement Among Intracerebral Hemorrhage (ICH) Survivors up to 12 Months Post-injurySreekrishnan A, Leasure AC, Shi FD, Hwang DY, Schindler JL, Petersen NH, Gilmore EJ, Kamel H, Sansing LH, Greer DM, Sheth KN. Functional Improvement Among Intracerebral Hemorrhage (ICH) Survivors up to 12 Months Post-injury. Neurocritical Care 2017, 27: 326-333. PMID: 28685394, PMCID: PMC5700855, DOI: 10.1007/s12028-017-0425-4.
Perihematomal Edema Expansion Rates and Patient Outcomes in Deep and Lobar Intracerebral HemorrhageGrunwald Z, Beslow LA, Urday S, Vashkevich A, Ayres A, Greenberg SM, Goldstein JN, Leasure A, Shi FD, Kahle KT, Battey TW, Simard JM, Rosand J, Kimberly WT, Sheth KN. Perihematomal Edema Expansion Rates and Patient Outcomes in Deep and Lobar Intracerebral Hemorrhage. Neurocritical Care 2016, 26: 205-212. PMID: 27844466, PMCID: PMC5378491, DOI: 10.1007/s12028-016-0321-3.
Intracerebral Hemorrhage Location and Functional Outcomes of Patients: A Systematic Literature Review and Meta-AnalysisSreekrishnan A, Dearborn JL, Greer DM, Shi FD, Hwang DY, Leasure AC, Zhou SE, Gilmore EJ, Matouk CC, Petersen NH, Sansing LH, Sheth KN. Intracerebral Hemorrhage Location and Functional Outcomes of Patients: A Systematic Literature Review and Meta-Analysis. Neurocritical Care 2016, 25: 384-391. PMID: 27160888, DOI: 10.1007/s12028-016-0276-4.
Rate of Perihematomal Edema Expansion Predicts Outcome After Intracerebral HemorrhageUrday S, Beslow LA, Dai F, Zhang F, Battey TW, Vashkevich A, Ayres AM, Leasure AC, Selim MH, Simard JM, Rosand J, Kimberly WT, Sheth KN. Rate of Perihematomal Edema Expansion Predicts Outcome After Intracerebral Hemorrhage. Critical Care Medicine 2016, 44: 790-797. PMID: 26757167, PMCID: PMC4859217, DOI: 10.1097/ccm.0000000000001553.
Treatment of Edema Associated With Intracerebral HemorrhageLeasure A, Kimberly WT, Sansing LH, Kahle KT, Kronenberg G, Kunte H, Simard JM, Sheth KN. Treatment of Edema Associated With Intracerebral Hemorrhage. Current Treatment Options In Neurology 2016, 18: 9. PMID: 26874842, DOI: 10.1007/s11940-015-0392-z.

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