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Zhe Jay Chen, PhD, FAAPM

Professor of Therapeutic Radiology; Vice Chair for Physics Research and Education, Therapeutic Radiology; Director, Cesium Irradiation Shared Resource for Yale Cancer Center, Therapeutic Radiology; Smilow Chief Physicist; Director of Medical Physics Residency Program

Contact Information

Zhe Jay Chen, PhD, FAAPM

Patient Care Location

Office Location

Mailing Address

  • Therapeutic Radiology

    PO Box 208040

    New Haven, CT 06520-8040

    United States



Dr. Zhe (Jay) Chen received his B.S. degree in theoretical physics from Fudan University in Shanghai, China in 1982. In the same year, he was selected by Nobel Laureate T.D. Lee's China-US Physics Scholarship program to pursue graduate study in physics in the United States. After receiving a Ph.D. degree in theoretical condensed matter physics from the City University of New York in 1989, he continued postdoctoral research in physics at Brown University from 1989 to 1992. Driven by the desire to put his training in theoretical physics to more practical applications, he joined the Department of Radiation Oncology of the State University of New York (SUNY) at Stony Brook in 1992. He found the application of radiation physics and radiobiology in radiation therapy not only helpful to cancer patients but also intellectually stimulating and satisfying to a physicist. He became a clinical medical physicist and an assistant professor of research in the Health Science Center and SUNY School of Medicine at Stony Brook. In 1995, he joined the Department of Therapeutic Radiology at Yale-New Haven Hospital and Yale University School of Medicine and has stayed here since. In addition to providing clinical medical physics support in daily patient care, he has been actively involved in teaching physics of radiation therapy to radiation oncology and medical physics residents and in conducting original research towards better understanding and effective use of physics in radiation therapy. He has authored and/or coauthored over 100 peer-reviewed research articles, 14 book chapters and reviews, and over 180 published research abstracts. He has been a research investigator on 5 federal government supported research grants and was the principal investigator of a NIH R01 research grant investigating the effects of prostate edema on the treatment of early-stage prostate cancer using permanent interstitial brachytherapy.

Education & Training

  • Postdoctoral fellow
    Brown University (1992)
  • PhD
    City University of New York (1989)
  • MPhil
    City University of New York (1985)
  • BS
    Fudan University (1982)

Honors & Recognition

AwardAwarding OrganizationDate
Visiting ProfessorUniversity of Pennsylvania (Radiation Physics)2018
Special Achievement of Excellence AwardYale New Haven Hospital2017
Volunteer Service AwardAmerican Board of Radiology2015
FellowAmerican Association of Physicists in Medicine2012
Master of Arts (Honorary)Yale University2012
NIH R01 Research Grant AwardNational Cancer Institute2008
Distinguished Service Award, Board of DirectorsAmerican Association of Physicists in Medicine2008
President (Service Award)Connecticut Area Medical Physics Society2002

Professional Service

American Association of Physicists in Medicine (AAPM)Chair of Task Group No. 267 - Biophysical models and tools for the planning and evaluation of selected brachytherapy modalities2014 - Present
American Society for Radiation Oncology (ASTRO)Member, Physics Core Curriculum Committee2014 - Present
American Association of Physicists in Medicine (AAPM)Member, Working Group on Brachytherapy Clinical Applications2013 - Present
International Journal of Radiation Oncology, Biology, PhysicsAssociate Senior Editor2011 - 2014
American Association of Physicists in Medicine (AAPM)Member, Radiation Oncology Medical Physics Education Subcommittee2011 - Present
American Board of Radiology (ABR), Oral ExaminerOral Examiner2010 - Present
Italian Ministry of Health, Department of ResearchResearch Grant Review2009 - 2012
US Army, Department of DefenseResearch Grants of congressionally directed medical research programs (CDMRP)2009
American Association of Physicists in MedicineMember, Imaging for Treatment Assessment Work Group2008 - 2014
American Association of Physicists in MedicineMember, Task Group No. 137 - AAPM Recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer.2006 - 2010
American Society for Radiation OncologyMember2006 - Present
Medical PhysicsGuest Associate Editor & Reviewer2005 - Present
Connecticut Area Medical Physics SocietyMember1996 - Present
American Association of Physicists in MedicineMember1993 - Present

Departments & Organizations