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Yujun Cai, PhD

Assistant Professor of Surgery (Vascular)

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Yujun Cai, PhD

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Dr. Cai joined Yale School of Medicine from Beth Israel Deaconess Medical Center, Harvard Medical School, Boston. Before moving to Boston, he was a Postdoctoral Associate and then a junior faculty in Aab Cardiovascular Research Institute at the University of Rochester.

Dr. Cai is a Principal Investigator at Yale. His overall research focuses on understanding the molecular mechanisms of cyclic nucleotide signaling in the pathogenesis of arterial and venous disorders. He has a longstanding interest in investigating the function, molecular mechanisms, and therapeutic potential of phosphodiesterase (PDE) in cardiovascular diseases. Dr. Cai has expertise in the areas of inflammation, extracellular matrix, and lysosome function related to vascular diseases. He uses multiple approaches including RNA-Seq/bioinformatics, proteomics, in vitro primary cell culture, state-of-art in vivo rodent surgical models of diseases, human specimens from patients, and transgenic mice, and collaborates with vascular biologists, vascular surgeons, bioengineers, gene/drug delivery experts, and bioinformatics experts to achieve his research goals.

Education & Training

  • Postdoctoral Associate
    University of Rochester (2012)
  • PhD
    Lanzhou University (2003)

Honors & Recognition

AwardAwarding OrganizationDate
Transformational Project AwardAmerican Heart Association2019
The Best Poster Award for Center of Vascular Biology ResearchBeth Israel Deaconess Medical Center, Harvard Medical School2016
Scientist Development GrantAmerican Heart Association2013
Postdoctoral Fellowship AwardChina Postdoctoral Science Foundation2004

Departments & Organizations