2023
Recent Vitamin K Antagonist Use and Intracranial Hemorrhage After Endovascular Thrombectomy for Acute Ischemic Stroke
Mac Grory B, Holmes D, Matsouaka R, Shah S, Chang C, Rison R, Jindal J, Holmstedt C, Logan W, Corral C, Mackey J, Gee J, Bonovich D, Walker J, Gropen T, Benesch C, Dissin J, Pandey H, Wang D, Unverdorben M, Hernandez A, Reeves M, Smith E, Schwamm L, Bhatt D, Saver J, Fonarow G, Peterson E, Xian Y. Recent Vitamin K Antagonist Use and Intracranial Hemorrhage After Endovascular Thrombectomy for Acute Ischemic Stroke. JAMA 2023, 329: 2038-2049. PMID: 37338878, PMCID: PMC10282891, DOI: 10.1001/jama.2023.8073.Peer-Reviewed Original ResearchConceptsRisk of sICHSymptomatic intracranial hemorrhageVitamin K antagonistsAcute ischemic strokeSecondary end pointsEndovascular thrombectomyVKA useIschemic strokeHospital mortalityEnd pointIntracranial hemorrhageOral vitamin K antagonistsVitamin K antagonist useGuidelines-Stroke programPrior VKA usePrimary end pointObservational cohort studyLarge vessel occlusionRisk of complicationsAmerican Heart AssociationUse of anticoagulantsSignificant differencesHospital presentationSICH riskAntagonist use
2012
Temporal Trends and Predictors in the Use of Aldosterone Antagonists Post-Acute Myocardial Infarction
Rassi A, Cavender M, Fonarow G, Cannon C, Hernandez A, Peterson E, Peacock W, Laskey W, Rosas S, Zhao X, Schwamm L, Bhatt D. Temporal Trends and Predictors in the Use of Aldosterone Antagonists Post-Acute Myocardial Infarction. Journal Of The American College Of Cardiology 2012, 61: 35-40. PMID: 23137936, DOI: 10.1016/j.jacc.2012.08.1019.Peer-Reviewed Original ResearchMeSH KeywordsAgedDiabetes MellitusDrug PrescriptionsDrug UtilizationFemaleGuideline AdherenceHeart FailureHospital Bed CapacityHumansKidney DiseasesMaleMineralocorticoid Receptor AntagonistsMultivariate AnalysisMyocardial InfarctionMyocardial RevascularizationPatient DischargePractice Guidelines as TopicRegistriesSmokingStroke VolumeUnited StatesConceptsPost-acute myocardial infarctionAldosterone antagonist useAldosterone antagonist therapyAldosterone antagonistsEjection fractionAntagonist useEligible patientsAntagonist therapyHospital dischargeHeart failureMyocardial infarctionActual prescribing patternsGuideline-based therapyAbsence of contraindicationsHistory of diabetesPost-AMI patientsHigher ejection fractionAmerican Heart AssociationLarger hospital sizeCoronary revascularizationPrescribing patternsAMI patientsKidney dysfunctionPost-AMITobacco abuse