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Jonathan Weber, MA, PA-C, DFAAPA

he/him/his
Assistant Professor in the Physician Associate Program, Department of Medicine
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Additional Titles

Director of Didactic Education, Department of Medicine, Physician Associate Program

Course Director, Prevention, Population & Patient-Centered Medicine, Department of Medicine, Physician Associate Program

Course Co-Director, Clinical Medicine & Pharmacology, Internal Medicine

About

Titles

Assistant Professor in the Physician Associate Program, Department of Medicine

Director of Didactic Education, Department of Medicine, Physician Associate Program; Course Director, Prevention, Population & Patient-Centered Medicine, Department of Medicine, Physician Associate Program; Course Co-Director, Clinical Medicine & Pharmacology, Internal Medicine

Biography

Jonathan is assistant professor of medicine, director of didactic education and course director for prevention, populations and patient-centered medicine in the Yale School of Medicine Physician Associate Program. He has practiced internal medicine in the Yale New Haven Health and Yale University health systems for 27 years. He currently practices at the Yale Medicine Diabetes Center, the joint clinical practice of the Yale School of Medicine and Yale New Haven Health System. He works with medically complex patients on diabetes management specializing on the integration of diabetes technologies and personalized lifestyle medicine.

Previously, he practiced as a hospitalist, primary care, urgent care and athletic medicine clinician. Throughout his career, Jonathan has remained active in PA education, program administration and leadership. Chief academic interests and expertise include chronic disease management, AI care innovations, lifestyle medicine, comprehensive wellness, psychosocial communication, ethically vulnerable populations and health equity.

He has remained committed to advocacy and professional service. As past chair of legislative affairs for the CT Academy of PAs, he has been responsible for leading major health care reform efforts resulting in modernization of the PA Practice Act and improved patient care for CT residents. He is the recipient of several awards for his clinical service, teaching and professional service including recognition as a distinguished fellow by the American Academy of Physician Associates.

Major responsibilities as Director of Didactic Education include:

  • Development, coordination & delivery of academic curriculum
  • Maintenance of national accreditation standards
  • Course Director of Prevention, Populations & Patient-Centered Medicine master course
  • Course Co-Director of Pharmacology and Clinical Medicine master courses
  • Academic advisor & mentor to graduate medical students
  • Participation in School of Medicine & Program committees: Diversity, Admissions, Curriculum & Educational Policy, Academic Progress & Program Assessment


Last Updated on June 21, 2025.

Appointments

Other Departments & Organizations

Education & Training

PA-C
Yale University School of Medicine, Physician Associate (1998)
MA
Michigan State University, Education (1991)
BA
Saint Olaf College, Biology (1985)

Advanced Training & Certifications

Advancement of Clinician-Educator Scholarship Program
Yale School of Medicine, Department of Internal Medicine (2024)
Collaborative Behavioral Health and Addiction Medicine in Primary Care (CHAMP) Program
Yale School of Medicine, Department of Internal Medicine (2021)

Research

Overview

My academic and scholarly interests focus on improving clinical outcomes and quality of life for patients with chronic diseases through the clinical practice guidelines development and the design, evaluation, and delivery of effective graduate medical curriculum. I am nationally known for leading diabetes care and technology workshops and presentations. In 2025, I coauthored the first clinical practice guideline, titled “Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults.” with a select group of multi-disciplinary experts. This landmark guideline offers clear, actionable, and evidence-based strategies for helping individuals with prediabetes or type 2 diabetes optimize their lifestyle behaviors, sustain positive changes, and potentially reduce or eliminate the need for medications. I am also thrilled to have co-authored with first author and graduate PA student mentee, Jay Gandhi, a retrospective study on the use of telemedicine in diabetes care delivery that is currently in press by the Journal of Diabetes Science and Technology

Additionally, I worked with a select group of providers to develop two YNHHS Care Pathways for pre-diabetes and type 2 diabetes and have collaborated with the American Academy of Physician Associates (AAPA), the Endocrine Society, the American Academy of Family Physicians (AAFP), and the American Association of Nurse Practitioners (AANP) to develop enduring CME curriculum on diabetes management. Locally, I have collaborated and published educational research abstracts and poster presentations with several Yale faculty for the Obesity Society, the American College of Lifestyle Medicine and for the Yale Medical Education conference on novel obesity, transgender care and lifestyle medicine curriculum respectively.

Medical Research Interests

Biotechnology; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Healthy Lifestyle

Public Health Interests

Health Systems Reform; Chronic Diseases; Behavioral Health; End-of-life Care

Research at a Glance

Yale Co-Authors

Frequent collaborators of Jonathan Weber's published research.

Publications

Featured Publications

  • DLE: Advancing PA Leadership in the Management of Type 2 Diabetes | Module 7 - The Cardiorenal Syndrome (CRS) and New Concepts in Preventing Diabetic Kidney Disease (DKD)
    Weber J, DePalma S, Juergensen P, Leger M. Diabetes Leadership Edge | Module 7 - The Cardiorenal Syndrome (CRS) and New Concepts in Preventing Diabetic Kidney Disease (DKD). 2020. This activity has been reviewed by the AAPA Review Panel and is compliant with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits.
    Peer-Reviewed Educational Materials
  • Diabetes Leadership Edge: Module 4 - Pharmacotherapy Part 1: Treatment Algorithm and Non-Insulin Therapies
    DePalma S, Juergensen P, Leger M, Weber J. (Reviewers/ Editors) Diabetes Leadership Edge | Module 4 - Pharmacotherapy Part 1: Treatment Algorithm and Non-Insulin Therapies. 2020. This activity has been reviewed by the AAPA Review Panel and is compliant with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits.
    Peer-Reviewed Educational Materials
  • Diabetes Leadership Edge: Module 5 - Pharmocotherapy Part 2: Insulin Therapy and Challenging Cases
    DePalma S, Juergensen P, Leger M, Weber J. (Reviewers/ Editors) Diabetes Leadership Edge | Module 5 - Pharmocotherapy Part 2: Insulin Therapy and Challenging Cases. 2020. This activity has been reviewed by the AAPA Review Panel and is compliant with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits.
    Peer-Reviewed Educational Materials
  • Current and Future State of Cardiovascular Disease and Type 2 Diabetes - Prediabetes: A Primary Call to Action
    Purnell J, Unger J, Weber J, Thompson A. Endocrine Society, AAFP, AAPA & AANP National Education Program CME Series. Current and Future State of Cardiovascular Disease and Type 2 Diabetes - Prediabetes: A Primary Call to Action. 2020. 1.0 Category 1 AAPA CME credits
    Peer-Reviewed Educational Materials
  • Current and Future State of Cardiovascular Disease and Type 2 Diabetes - Patient-Centered Management of Diabetes and Prevention of Cardiovascular Disease
    Purnell J, Unger J, Weber J, Thompson A. Endocrine Society, AAFP, AAPA & AANP National Education Program CME Series. Current and Future State of Cardiovascular Disease and Type 2 Diabetes - Patient-Centered Management of Diabetes and Prevention of Cardiovascular Disease. 2020. 1.0 Category 1 AAPA CME credits
    Peer-Reviewed Educational Materials
  • Current and Future State of Cardiovascular Disease and Type 2 Diabetes - Managing Macrovascular Complications in Patients with Diabetes
    Purnell J, Unger J, Weber J, Thompson A. Endocrine Society, AAFP, AAPA & AANP National Education Program – 3 case CME Series. Current and Future State of Cardiovascular Disease and Type 2 Diabetes - Managing Macrovascular Complications in Patients with Diabetes. 2020. 1.0 Category 1 AAPA CME credits
    Peer-Reviewed Educational Materials
  • Telemedicine decreases no-show rates and achieves comparable outcomes in publicly insured patients with diabetes
    Gandhi J, Doolittle B, Weber J. Telemedicine decreases no-show rates and achieves comparable outcomes in publicly insured patients with diabetes. Journal of Diabetes Science and Technology. (In Press; Accepted 2/25/25)
    Peer-Reviewed Original Research In Press

Academic Achievements & Community Involvement

Activities

  • activity

    Educational Policy and Curriculum Committee, Physician Associate Program

  • activity

    Admissions Committee, Physician Associate Program

  • activity

    Academic Progress Committee, Physician Associate Program

  • activity

    Program Assessment Committee, Physician Associate Program

  • activity

    Self-Assessment Committee, Physician Associate Program

Honors

  • honor

    Jack Cole Society Award

  • honor

    American Academy of Physician Associates Distinguished Fellow

  • honor

    Peer-Appointed Faculty Member

  • honor

    “Inspiring Yale” Honoree

  • honor

    Annual Professional Service Award

Teaching & Mentoring

Mentoring

  • Deepak Sharma, PA-C

    Postgrad associate
    2024 - 2024
  • Jay Gandhi, MMSc, PA-C

    Postgrad associate
    2022 - 2023

Clinical Care

Overview

Jonathan Weber helps patients with diabetes at Yale Medicine’s Diabetes Center manage all aspects of their disease. He specializes in treating patients with kidney issues or other complications caused by diabetes.

“Working together with patients to find the best solutions to help them manage their diabetes and prevent diabetes-related complications is very rewarding,” Weber says.

He says he enjoys helping patients take steps to gain more control over their diabetes and make lifestyle changes such as eating healthier or exercising more to improve their overall health.

“I am interested in sharing what we know about lifestyle medicine along with current and emerging prescription therapies that meet patients’ needs and fit best into their lives,” he says. “The burdens that come with any chronic disease can be challenging. With a consistent and strong ‘therapeutic alliance’ between the patient and provider, I believe we can overcome any challenge together.”

Weber has practiced internal medicine for more than two decades in the Yale New Haven Health system.

Clinical Specialties

Diabetes Medicine & Management; Endocrinology; General Internal Medicine

Fact Sheets

Board Certifications

  • Physician Assistant - Medical

    Certification Organization
    National Commission on Certification of Physician Assistants
    Original Certification Date
    1998

Yale Medicine News

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Contacts

Academic Office Number
Secondary Academic Office Number
Appointment Number
Office Fax Number

Administrative Support

Locations

  • Yale Physician Associate Program

    Academic Office

    100 Church Street South, Ste A250

    New Haven, CT 06519

    General Information

    203.785.2860
  • Patient Care Locations

    Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.