Jon Koff, MD
Cards
About
Titles
Associate Professor Term
Associate Director, Fellowship Research, Pulmonary, Critical Care & Sleep Medicine; Medical Director, Center for Phage Biology & Therapy, Yale University; Director, Adult Cystic Fibrosis ProgramBiography
Dr. Koff received his undergraduate degree from Hamilton College and his medical degree from Case Western Reserve University. He completed residency training in Internal Medicine at Brown University. He then completed fellowship training in Pulmonary & Critical Care Medicine at the University of California, San Francisco (UCSF). This included research in the Cardiovascular Research Institute in the laboratory of his mentor, Jay A. Nadel, M.D., and dedicated fellowship training in adult cystic fibrosis and lung transplantation. In 2011, Dr. Koff joined the faculty at Yale University to Direct the Adult Cystic Fibrosis Program and to continue his research that focuses on pulmonary innate immunity. Dr. Koff is Medical Director of Yale's Center for Phage Biology & Therapy in which he focuses on bacteriophage therapy for multi-drug resistant infections.
Appointments
Pulmonary, Critical Care & Sleep Medicine
Associate Professor on TermPrimary
Other Departments & Organizations
- Adult Cystic Fibrosis Program
- CPIRT - Center for Pulmonary Injury, Inflammation, Repair and Therapeutics
- Internal Medicine
- Koff Laboratory
- Pulmonary, Critical Care & Sleep Medicine
- Winchester Center for Lung Disease
- Yale Medicine
- Yale Ventures
Education & Training
- Fellowship
- University of California - San Francisco (2008)
- Fellowship
- University of California - San Francisco (2008)
- MD
- Case Western Reserve University School of Medicine (2000)
- BA
- Hamilton College, World Politics
Research
Overview
Medical Subject Headings (MeSH)
Academic Achievements and Community Involvement
Clinical Care
Overview
Jonathan Koff, MD, a pulmonary and critical care physician, is director of the Yale Medicine Adult Cystic Fibrosis Program. He chose pulmonary medicine in part because his grandfather had emphysema. “I wanted to better understand how the disease affected him,” he says.
Dr. Koff was drawn to cystic fibrosis, which is usually diagnosed in childhood, because he was intrigued by the complexity of this genetic disease, which causes recurrent lung infections, and digestive and nutritional problems, among other issues. He works with a multidisciplinary team that includes a nurse, a nutritionist, a physical therapist, a social worker, and respiratory therapists. “We continue to see our patients do better clinically with the multidisciplinary team-based care approach,” he says. He is optimistic about new treatments for cystic fibrosis, such as recently approved therapies that target specific genetic mutations.
An associate professor of medicine (pulmonary) at Yale School of Medicine, Dr. Koff also works in the medical intensive care unit at Yale New Haven Hospital, and conducts laboratory and translational research that focuses on viral infections in asthma and cystic fibrosis. He serves on the board of the Connecticut Chapter of the Cystic Fibrosis Foundation.
Clinical Specialties
Fact Sheets
Adult Cystic Fibrosis
Learn More on Yale MedicineCystic Fibrosis in Children
Learn More on Yale MedicineCoronavirus
Learn More on Yale MedicineLong COVID (Post-COVID Conditions, PCC)
Learn More on Yale Medicine
Yale Medicine News
Links & Media
News
- February 13, 2022
New Yale Center to Advance Phage Understanding, Treatments, Training, Education
- December 16, 2020
Discoveries & Impact (December 2020)
- April 03, 2020
Have a Condition That Can Affect Breathing? What You Need to Know About COVID-19.
- May 07, 2019
Meet Yale Internal Medicine: Jonathan Koff, MD, Associate Professor of Medicine (Pulmonary, Critical Care, and Sleep Medicine) and Director, Adult Cystic Fibrosis Program
Get In Touch
Contacts
Locations
The Anlyan Center
Lab
The Anlyan Center
Academic Office
Patient Care Locations
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