Hee-Hoon Kim, PhD
Postdoctoral FellowAbout
Titles
Postdoctoral Fellow
Biography
Hee-Hoon is a postdoctoral associate in the Dixit lab. His primary focus revolves around discovering immunometabolic pathways with the potential to mitigate inflammation and extend health span. In particular, he delves into the characterization of both metabolic and immunological changes occurring within the adipose tissue microenvironment during the aging process, utilizing a novel healthy aging model organism.
Appointments
Education & Training
- Postdoctoral researcher
- Korea Advanced Institute of Science and Technology (2023)
- PhD
- Korea Advanced Institute of Science and Technology, Graduate School of Medical Science and Engineering (2022)
Research
Research at a Glance
Publications Timeline
A big-picture view of Hee-Hoon Kim's research output by year.
18Publications
Publications
2024
Defying "IL-11ness" by inhibiting inflammation: Strategy for health and longevity.
Kim HH, Dixit VD. Defying "IL-11ness" by inhibiting inflammation: Strategy for health and longevity. Cell Metab 2024, 36: 1911-1913. PMID: 39232279, DOI: 10.1016/j.cmet.2024.08.003.Commentaries, Editorials and LettersCX3CR1+ macrophages interact with hepatic stellate cells to promote hepatocellular carcinoma through CD8+ T cell suppression.
Jeong JM, Choi SE, Shim YR, Kim HH, Lee YS, Yang K, Kim K, Kim MJ, Chung KPS, Kim SH, Byun JS, Eun HS, Jeong WI. CX3CR1+ macrophages interact with hepatic stellate cells to promote hepatocellular carcinoma through CD8+ T cell suppression. Hepatology 2024 PMID: 39028913, DOI: 10.1097/HEP.0000000000001021.Peer-Reviewed Original Research
2023
xCT-mediated glutamate excretion in white adipocytes stimulates interferon-γ production by natural killer cells in obesity.
Kim HH, Shim YR, Kim HN, Yang K, Ryu T, Kim K, Choi SE, Kim MJ, Woo C, Chung KPS, Hong SH, Shin H, Suh JM, Jung Y, Hwang GS, Kim W, Kim SH, Eun HS, Seong JK, Jeong WI. xCT-mediated glutamate excretion in white adipocytes stimulates interferon-γ production by natural killer cells in obesity. Cell Rep 2023, 42: 112636. PMID: 37310859, DOI: 10.1016/j.celrep.2023.112636.Peer-Reviewed Original ResearchComprehensive transcriptomic analysis and meta-analysis identify therapeutic effects of N-acetylcysteine in nonalcoholic fatty liver disease.
Yang K, Kim HH, Shim YR, Ryu T, Kim CW. Comprehensive transcriptomic analysis and meta-analysis identify therapeutic effects of N-acetylcysteine in nonalcoholic fatty liver disease. Front Pharmacol 2023, 14: 1186582. PMID: 37256235, DOI: 10.3389/fphar.2023.1186582.Peer-Reviewed Original ResearchExosome-Based Delivery of Super-Repressor IκBα Alleviates Alcohol-Associated Liver Injury in Mice.
Kim HH, Shim YR, Choi SE, Falana TE, Yoo JK, Ahn SH, Park M, Seo H, Choi C, Jeong WI. Exosome-Based Delivery of Super-Repressor IκBα Alleviates Alcohol-Associated Liver Injury in Mice. Pharmaceutics 2023, 15 PMID: 36839957, DOI: 10.3390/pharmaceutics15020636.Peer-Reviewed Original ResearchThe Efficacy of Panax ginseng for the Treatment of Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Preclinical Studies.
Yang K, Kim HH, Shim YR, Song MJ. The Efficacy of Panax ginseng for the Treatment of Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Preclinical Studies. Nutrients 2023, 15 PMID: 36771427, DOI: 10.3390/nu15030721.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCatecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease.
Kim HH, Shim YR, Choi SE, Kim MH, Lee G, You HJ, Choi WM, Yang K, Ryu T, Kim K, Kim MJ, Woo C, Chung KPS, Hong SH, Eun HS, Kim SH, Ko G, Park JE, Gao B, Kim W, Jeong WI. Catecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease. Exp Mol Med 2023, 55: 158-170. PMID: 36631664, DOI: 10.1038/s12276-022-00921-x.Peer-Reviewed Original ResearchIsolation of Hepatic Stellate Cells and Lymphocytes for Co-culture Systems.
Kim HH, Kim K, Hong SH, Jeong WI. Isolation of Hepatic Stellate Cells and Lymphocytes for Co-culture Systems. Methods Mol Biol 2023, 2669: 111-128. PMID: 37247057, DOI: 10.1007/978-1-0716-3207-9_7.Chapters
2022
NAMPT mitigates colitis severity by supporting redox-sensitive activation of phagocytosis in inflammatory macrophages.
Hong SM, Lee AY, Hwang SM, Ha YJ, Kim MJ, Min S, Hwang W, Yoon G, Kwon SM, Woo HG, Kim HH, Jeong WI, Shen HM, Im SH, Lee D, Kim YS. NAMPT mitigates colitis severity by supporting redox-sensitive activation of phagocytosis in inflammatory macrophages. Redox Biol 2022, 50: 102237. PMID: 35063804, DOI: 10.1016/j.redox.2022.102237.Peer-Reviewed Original Research
2021
Metabotropic Glutamate Receptor 5 in Natural Killer Cells Attenuates Liver Fibrosis by Exerting Cytotoxicity to Activated Stellate Cells.
Choi WM, Ryu T, Lee JH, Shim YR, Kim MH, Kim HH, Kim YE, Yang K, Kim K, Choi SE, Kim W, Kim SH, Eun HS, Jeong WI. Metabotropic Glutamate Receptor 5 in Natural Killer Cells Attenuates Liver Fibrosis by Exerting Cytotoxicity to Activated Stellate Cells. Hepatology 2021, 74: 2170-2185. PMID: 33932306, DOI: 10.1002/hep.31875.Peer-Reviewed Original Research
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Mailing Address
Pathology
310 Cedar Street, BML 316A
New Haven, Connecticut 06510
United States
Locations
Brady Memorial Laboratory
Lab
310 Cedar Street, Fl 3rd, Rm 316A
New Haven, CT 06510