Fred Sigworth studied applied physics at Caltech and was a graduate student at Yale, working in the neuroscience laboratory of Charles F. Stevens. He received the PhD in physiology from Yale in 1979 and was a postdoc in the laboratory of Erwin Neher in Göttingen, Germany where he was a co-developer of patch-clamp techniques for single-channel electrophysiology. He returned to Yale as a faculty member at Yale in 1984. His current research is in the structural biology of ion-channel proteins, making use of novel cryo-EM methods. "How do I see the scientific enterprise? An old book puts it this way: one generation commends God's works to another. It is a great privilege to unravel the workings of ion channels, and to pass on the excitement about these molecular machines to students, colleagues and anyone else who will listen!"
|Member||National Academy of Sciences||2016|
|Bohmfalk Teaching Prize||Yale School of Medicine||2002|
|K. C. Cole Award||Biophysical Society||1997|
|Yale Science and Engineering Award||Yale University||1996|
|Jacob Javits Neuroscience Investigator Award||NIH||1992|
|Fellow||Alexander von Humboldt Foundation||1979|