Featured Publications
White and Brown Adipose Tissue in Obesity and Diabetes
Leitner B, Martinez-Tellez B. White and Brown Adipose Tissue in Obesity and Diabetes. 2020, 55-69. DOI: 10.1007/978-3-030-53370-0_5.ChaptersWhite adipose tissueBrown adipose tissueAdipose tissueTotal body massSevere insulin resistanceAdipose tissue typesEnergy storage tissueBody massInsulin resistanceObese humansImmune regulationFunctional roleType 2Hormone productionNoninvasive imagingPotential mechanismsEnergy expenditureObesityDiabetesRecent scientific advancesTissueDynamic tissueHuman energy expenditureHuman physiologyFuture investigations
2021
501-P: Lower Plasma Membrane Sn-1,2-Diacylglycerol Content and PKCepsilon/theta Activity Explain the Athlete’s Paradox
GASPAR R, LYU K, HUBBARD B, LEITNER B, LUUKKONEN P, HIRABARA S, SAKUMA I, NASIRI A, ZHANG D, KAHN M, CLINE G, PAULI J, PERRY R, PETERSEN K, SHULMAN G. 501-P: Lower Plasma Membrane Sn-1,2-Diacylglycerol Content and PKCepsilon/theta Activity Explain the Athlete’s Paradox. Diabetes 2021, 70 DOI: 10.2337/db21-501-p.Peer-Reviewed Original ResearchHigh-fat diet feedingMuscle insulin sensitivityEX miceInsulin sensitivitySpouse/partnerGlucose toleranceIntramyocellular lipidsAthlete's paradoxRC micePKCθ translocationHyperinsulinemic-euglycemic clamp studiesGilead SciencesJanssen ResearchMuscle TAG contentMuscle triglyceride contentMale C57BL/6J miceImproved glucose toleranceNovo NordiskMuscle insulin resistanceNovo Nordisk FoundationBoehringer Ingelheim PharmaceuticalsChow feedingHFD groupHFD miceInsulin resistance