Hanno C. Erythropel, PhD
he/him/his
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About
Titles
Research Scientist CENV
Education & Training
- PhD
- McGill University, Chemical Engineering (2016)
- MSc
- McGill University, Chemical Engineering (2011)
- MSc
- Carl-von-Ossietzky Universität Oldenburg, Chemistry (2009)
Research
Publications
Featured Publications
Synthetic Cooling Agent and Other Flavor Additives in “Non-Menthol” Cigarettes Marketed in California and Massachusetts After Menthol Cigarette Bans
Jabba S, Erythropel H, Anastas P, Zimmerman J, Jordt S. Synthetic Cooling Agent and Other Flavor Additives in “Non-Menthol” Cigarettes Marketed in California and Massachusetts After Menthol Cigarette Bans. JAMA 2023, 330: 1689-1691. PMID: 37812408, PMCID: PMC10562986, DOI: 10.1001/jama.2023.17134.Peer-Reviewed Original ResearchGreen chemistry as just chemistry
Lane M, Rudel H, Wilson J, Erythropel H, Backhaus A, Gilcher E, Ishii M, Jean C, Lin F, Muellers T, Wang T, Torres G, Taylor D, Anastas P, Zimmerman J. Green chemistry as just chemistry. Nature Sustainability 2023, 6: 502-512. DOI: 10.1038/s41893-022-01050-z.Peer-Reviewed Original ResearchFormation of flavorant–propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids
Erythropel HC, Jabba SV, DeWinter TM, Mendizabal M, Anastas PT, Jordt SE, Zimmerman JB. Formation of flavorant–propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids. Nicotine & Tobacco Research 2018, 21: 1248-1258. PMID: 30335174, PMCID: PMC6698951, DOI: 10.1093/ntr/nty192.Peer-Reviewed Original ResearchConceptsFlavor aldehydesSolvent componentsNuclear magnetic resonance spectroscopyNovel chemical speciesReaction productsPhysiological aqueous solutionE-cigarette liquidsReactive chemical systemsToxicological propertiesCommercial e-liquidsMagnetic resonance spectroscopyE-liquidsAqueous mediaPropylene glycolAqueous solutionPotential toxicological effectsNew compoundsUltraviolet spectroscopyChemical speciesChemical reactionsGas chromatographyChemical systemsResonance spectroscopyToxicological effectsAldehydesDesigning for a green chemistry future
Zimmerman JB, Anastas PT, Erythropel HC, Leitner W. Designing for a green chemistry future. Science 2020, 367: 397-400. PMID: 31974246, DOI: 10.1126/science.aay3060.Peer-Reviewed Original Research
2024
A review of the toxicity of ingredients in e-cigarettes, including those ingredients having the FDA’s “Generally Recognized as Safe (GRAS)” regulatory status for use in food
Kassem N, Strongin R, Stroup A, Brinkman M, El-Hellani A, Erythropel H, Etemadi A, Exil V, Goniewicz M, Kassem N, Klupinski T, Liles S, Muthumalage T, Noël A, Peyton D, Wang Q, Rahman I, Valerio L. A review of the toxicity of ingredients in e-cigarettes, including those ingredients having the FDA’s “Generally Recognized as Safe (GRAS)” regulatory status for use in food. Nicotine & Tobacco Research 2024, ntae123. PMID: 38783714, DOI: 10.1093/ntr/ntae123.Peer-Reviewed Original ResearchExtract Manufacturers AssociationE-cigarettesE-cigarette productsFood ingredientsFood additivesPrevalence of e-cigarette useGRAS substancesGRASE-liquidsE-cigarette useFoodIngredientsE-cigarette toxicityEvidence of adverse effectsProduct ingredientsToxicity of ingredientsE-liquid ingredientsDrug and Cosmetic ActOral consumptionRegulatory statusElectronic cigarettesChemical compoundsToxicological evaluationProduct labelsRefill liquidsChemical and physiological interactions between e-liquid constituents: cause for concern?
Strongin R, Sharma E, Erythropel H, Kassem N, Noël A, Peyton D, Rahman I. Chemical and physiological interactions between e-liquid constituents: cause for concern? Tobacco Control 2024, tc-2023-058546. PMID: 38658055, DOI: 10.1136/tc-2023-058546.Peer-Reviewed Original ResearchComparison of emissions across tobacco products: A slippery slope in tobacco control
El-Hellani A, Adeniji A, Erythropel H, Wang Q, Lamb T, Mikheev V, Rahman I, Stepanov I, Strongin R, Wagener T, Brinkman M. Comparison of emissions across tobacco products: A slippery slope in tobacco control. Tobacco Induced Diseases 2024, 22: 1-13. PMID: 38560551, PMCID: PMC10980913, DOI: 10.18332/tid/183797.Peer-Reviewed Original ResearchTobacco productsHeated tobacco productsTobacco controlElectronic cigarettesCombustible cigarettesNarrative reviewTobaccoCigaretteNon-target analysisSession lengthData reportingControlled laboratory settingAnalytical method developmentMatrix effectsAssurance measuresActual useLaboratory settingTrap emissionHookahMethod developmentInhaled smokeSmokingReviewAbsolute exposureStatistical analysis
2023
Mechanistic investigation of a Ni-catalyzed electrochemical reductive cleavage of the α-O-4 bond in the lignin model compound benzyl phenyl ether
Lin F, Petrović P, Tse H, Erythropel H, Lam J, Anastas P. Mechanistic investigation of a Ni-catalyzed electrochemical reductive cleavage of the α-O-4 bond in the lignin model compound benzyl phenyl ether. Green Chemistry 2023, 25: 9720-9732. DOI: 10.1039/d3gc01814h.Peer-Reviewed Original ResearchElectrochemical reductive cleavageBenzyl phenyl etherReductive cleavagePhenyl etherO bondReaction mechanismLignin αCarbon paper cathodeO bond scissionCP electrodePaper cathodeRole of methanolElectrode surfaceCatalyst surfaceDFT calculationsProton donorBond scissionRoom temperatureProton transferPhenoxy anionCatalytic cleavageO saltMechanistic routesBenzylic carbonInert atmosphereSynthetic cooling agent in oral nicotine pouch products marketed as ‘Flavour-Ban Approved’
Jabba S, Erythropel H, Woodrow J, Anastas P, O'Malley S, Krishnan-Sarin S, Zimmerman J, Jordt S. Synthetic cooling agent in oral nicotine pouch products marketed as ‘Flavour-Ban Approved’. Tobacco Control 2023, tc-2023-058035. PMID: 37380351, PMCID: PMC10753027, DOI: 10.1136/tc-2023-058035.Peer-Reviewed Original ResearchGas chromatography/mass spectrometryChromatography/mass spectrometryWS-3Oral nicotine pouchesSynthetic coolantsMass spectrometryChemical analysisSensory irritancyFlavor additivesAdditivesChemical contentFlavoring agentProductsIrritant activitySpectrometryFlavourantsEffective strategyExtractAgentsNicotine pouchesSynthetic Cooling Agents in California-Marketed "Non-menthol" Cigarette Brands Introduced After the State’s Menthol Ban
Jordt S, Erythropel H, Yang A, O'Malley S, Krishnan-Sarin S, Zimmerman J, Jabba S. Synthetic Cooling Agents in California-Marketed "Non-menthol" Cigarette Brands Introduced After the State’s Menthol Ban. 2023, a2633-a2633. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2633.Peer-Reviewed Original Research
Links & Media
News
- June 03, 2024Source: Scientific American
How Tobacco Companies Use Chemistry To Get Around Menthol Bans
- October 16, 2023
Chemical additives replace menthol in new ‘non-menthol’ cigarettes
- September 27, 2023
$20M Federal Grant Renewed for Yale Tobacco Center of Regulatory Science
- August 22, 2019
Juul Users Inhaling Chemicals Not Listed