Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsSven-Eric Jordt, PhD
he/him/his
Associate Professor of Anesthesiology, Pharmacology & Cancer Biology, University Program of Environmental Health (UPEH), Duke University School of MedicineAbout
Research
Publications
2025
The Concise Guide to PHARMACOLOGY 2025/26: Ion channels
Alexander S, Striessnig J, Gibb A, Mathie A, Veale E, Kelly E, Peach C, Armstrong J, Faccenda E, Harding S, Southan C, Davies J, Aldrich R, Attali B, Baggetta A, Becirovic E, Beech D, Biel M, Bill R, Caceres A, Catterall W, Chua H, Conner A, Danahay H, Davies P, De Clerq K, Delling M, Di Virgilio F, Falzoni S, Fang W, Fenske S, Fortuny-Gomez A, Fountain S, Chandy G, Ghovanloo M, Goldstein S, Gosling M, Grimm C, Grissmer S, Ha K, Hales T, Hammelmann V, Hanukoglu I, Hu M, Ijzerman A, Jabba S, Jarvis M, Jensen A, Jordt S, Kaczmarek L, Kellenberger S, Kennedy C, King B, Kitchen P, Liu Q, Lynch J, Manville R, Meades J, Mehlfeld V, Nicke A, Offermanns S, Pérez-Reyes E, Plant L, Pless S, Rash L, Ren D, Rubaiy H, Salman M, Sieghart W, Sivilotti L, Smart T, Snutch T, Tammaro P, Tian J, Trimmer J, Van den Eynde C, Vergani P, Vriens J, Waxman S, Wei A, Winn B, Wulff H, Xu H, Yang F, Yue L, Zhang X, Zhu M. The Concise Guide to PHARMACOLOGY 2025/26: Ion channels. British Journal Of Pharmacology 2025, 182: s152-s241. PMID: 41461580, DOI: 10.1111/bph.70231.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsConcise guidePoint-in-time recordHuman drug targetsFamily of drug targetsNomenclature guidanceDrug targetsDrug target familyPharmacological toolsConcise summariesIndividual drug targetsBiennial publicationCatalytic receptorsG protein-coupled receptorsBritish Journal of PharmacologyTarget familiesNuclear hormone receptorsPharmacological profileHormone receptorsClinical pharmacologyPharmacological targetsStyle of presentationInformationOnline databasesNC-IUPHARReceptorsTransient Receptor Potential channels (TRP) in GtoPdb v.2025.4
Blair N, McKemy D, Nilius B, Oancea E, Owsianik G, Riccio A, Sah R, Stotz S, Tian J, Tong D, Vriens J, Wu L, Xu H, Yang F, Yang W, Yue L, Liu Q, Liu B, Caceres A, Carvacho I, Chaudhuri D, Clapham D, De Clercq K, Delling M, Doerner J, Fan L, Grimm C, Ha K, Hu M, Jabba S, Jordt S, Julius D, Kahle K, Zhu M. Transient Receptor Potential channels (TRP) in GtoPdb v.2025.4. IUPHAR/BPS Guide To Pharmacology CITE 2025, 2025 DOI: 10.2218/gtopdb/f78/2025.4.Peer-Reviewed Original ResearchTRPC channelsTransient receptor potential channelsDetection of noxious heatCongenital stationary night blindnessCalcium-activated cationStore-operated channelsPlacental trophoblast cellsNMDA receptorsAdenosine diphosphate riboseSlow afterdepolarizationNoxious heatC-terminal kinase regionSplice variantsIntracellular ATP levelsCation channelsChannel activityNeurodegenerative disorder mucolipidosis type IVTRPA1 activationDepletion of intracellular calcium storesMucolipidosis type IVTRP channelsAssociated with conduction defectsDevelopment of heat hyperalgesiaDevelopment of thermal hyperalgesiaDynamic intracellular vesicular structuresModeling functional responses to pollutant exposure using modular hydrogel supported vascularized alveolosphere-on-a-chip
Perikamana S, Kumar V, Mogha P, Duncan L, Angel N, Tata A, Jabba S, Jordt S, Tata P, Varghese S. Modeling functional responses to pollutant exposure using modular hydrogel supported vascularized alveolosphere-on-a-chip. Biomaterials Science 2025, 13: 6046-6057. PMID: 40960519, PMCID: PMC12442856, DOI: 10.1039/d5bm00552c.Peer-Reviewed Original ResearchExtracellular matrix-based hydrogelsLow Young's modulusExtracellular matrixModular hydrogelsYoung's modulusHydrogelsMicrofluidic devicesExtracellular matrix proteinsAlveolar type 2Cellular contractilityMatrix stiffnessSize distributionDrug responseThree-dimensional cultureDisease mechanismsMatrixLung biologyAlveolar type 2 cellsAT2 cellsResponse to pollutant exposureCellsDrug discoveryLung fibroblastsMatrix degradationModulusPrevalence of Artificial Sweetener Neotame in US-Marketed Disposable E-Cigarettes
Erythropel H, Jabba S, Mellinghoff R, Garcia-Gallet V, Silinski P, Zimmerman J, Jordt S. Prevalence of Artificial Sweetener Neotame in US-Marketed Disposable E-Cigarettes. JAMA: The Journal Of The American Medical Association 2025, 334: 448-449. PMID: 40455485, PMCID: PMC12131167, DOI: 10.1001/jama.2025.7398.Peer-Reviewed Original ResearchTransient Receptor Potential channels (TRP) in GtoPdb v.2025.1
Blair N, McKemy D, Nilius B, Oancea E, Owsianik G, Riccio A, Sah R, Stotz S, Tian J, Tong D, Vriens J, Wu L, Xu H, Yang F, Yang W, Yue L, Liu Q, Liu B, Caceres A, Carvacho I, Chaudhuri D, Clapham D, De Clercq K, Delling M, Doerner J, Fan L, Grimm C, Ha K, Hu M, Jabba S, Jordt S, Julius D, Kahle K, Zhu M. Transient Receptor Potential channels (TRP) in GtoPdb v.2025.1. IUPHAR/BPS Guide To Pharmacology CITE 2025, 2025 DOI: 10.2218/gtopdb/f78/2025.1.Peer-Reviewed Original ResearchTRPC channelsTransient receptor potential channelsCongenital stationary night blindnessCalcium-activated cationStore-operated channelsAdenosine diphosphate riboseNumerous splice variantsNMDA receptorsActivate TRPA1Intracellular ATP levelsCation channelsChannel activityMicromolar concentrations of La3+Mucolipidosis type IVNeurodegenerative disorder mucolipidosis type IVDepletion of intracellular calcium storesTRP channelsRegulation of Ca2+ entryAssociated with conduction defectsDetection of noxious heatDevelopment of heat hyperalgesiaDevelopment of thermal hyperalgesiaDynamic intracellular vesicular structuresExtra-synaptic NMDA receptorsInvolvement of TRP channelsMarketing for Sensa: a ‘zero nicotine vapor product’ from a major tobacco company
Robichaud M, Talbot E, Ganz O, Mercincavage M, Erythropel H, Zimmerman J, Jabba S, Jordt S, Delnevo C. Marketing for Sensa: a ‘zero nicotine vapor product’ from a major tobacco company. Tobacco Control 2025, 35: 132-134. PMID: 39956632, PMCID: PMC12354010, DOI: 10.1136/tc-2024-059074.Peer-Reviewed Original ResearchCalifornia’s Visionary Tobacco Bill—Will the FDA Follow?
Jordt S, Jabba S. California’s Visionary Tobacco Bill—Will the FDA Follow? JAMA: The Journal Of The American Medical Association 2025, 333: 285-286. PMID: 39621329, PMCID: PMC12132922, DOI: 10.1001/jama.2024.22986.Peer-Reviewed Original ResearchHow Tobacco Companies Use Chemistry to Get around Menthol Bans
ZIMMERMAN J, ERYTHROPEL H, MUELLERS T, PETROVIC P, O’MALLEY S, Krishnan-Sarin S, JABBA S, JORDT S, ANASTAS P. How Tobacco Companies Use Chemistry to Get around Menthol Bans. Scientific American 2025, 332: 71-71. PMID: 39688992, PMCID: PMC12208286, DOI: 10.1038/scientificamerican012025-7utzdfyksaqx7txbhvuhtg.Peer-Reviewed Original Research
2024
Artificial Sweeteners in US-Marketed Oral Nicotine Pouch Products: Correlation With Nicotine Contents and Effects on Product Preference
Jabba S, Silinski P, Yang A, Ouyang W, Jordt S. Artificial Sweeteners in US-Marketed Oral Nicotine Pouch Products: Correlation With Nicotine Contents and Effects on Product Preference. Nicotine & Tobacco Research 2024, 28: 223-229. PMID: 39656927, PMCID: PMC12466937, DOI: 10.1093/ntr/ntae293.Peer-Reviewed Original ResearchOral nicotine pouchesWild-type miceReceptor-deficient miceEffects of nicotineIncreased nicotine consumptionSensory effects of nicotineNicotine pouch productsArtificial sweetenersDeficient miceNicotine consumptionSweet taste perceptionNicotine pouchesHigh-nicotineMiceNicotineSmokeless tobaccoAcesulfame-KLiquid chromatography-mass spectrometryWild-typeNicotine contentTaste perceptionTobacco productsArtificial sweeteners acesulfame-KReduced aversionStronger aversionIntroduction of nicotine analogue-containing oral pouch products in the United States
Jordt S, Jabba S. Introduction of nicotine analogue-containing oral pouch products in the United States. Tobacco Prevention & Cessation 2024, 10: 1-5. PMID: 39588526, PMCID: PMC11587819, DOI: 10.18332/tpc/195621.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- April 09, 2026
Research by Bagdas, Addy Named Best Paper in Basic Science by Society for Research on Nicotine and Tobacco
- August 07, 2024
Novel E-Cigarette Products Marketed to Contain Nicotine Analogs Instead of Nicotine Show Discrepancies Between Label Information and Contents
- June 03, 2024Source: Scientific American
How Tobacco Companies Use Chemistry To Get Around Menthol Bans
- September 27, 2023
$20M Federal Grant Renewed for Yale Tobacco Center of Regulatory Science
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