Yuan Lu, ScD
Assistant Professor of Medicine (Cardiology) and of Biomedical Informatics and Data Science and of Epidemiology (Chronic Diseases)Cards
Appointments
Contact Info
About
Titles
Assistant Professor of Medicine (Cardiology) and of Biomedical Informatics and Data Science and of Epidemiology (Chronic Diseases)
Biography
Dr. Lu was trained in epidemiology and global health, with a particular focus on cardiovascular diseases. She obtained both of her ScD and MSc Degrees in Global Health and Population at the Harvard School of Public Health. She works in the intersection of cardiovascular disease prevention, health equity, and digital health, using implementation science methods to resolve real-world issues. Her long-term goal is to improve care, outcomes, and equity of cardiovascular diseases by designing and implementing technology-based interventions.
She successfully completed an NHLBI K12 career development award in implementation science. During this award, she harnessed electronic health records from the Yale New Haven Health System to identify patients with persistent hypertension and designing decision support systems to improve their care. Currently, Dr. Lu serves as the Principal Investigator for an NIH R01 grant, where she leverages real-world data from five electronic health record databases encompassing over 100 million US adults. The goal of this endeavor is to generate real-world evidence that informs decisions regarding hypertension treatment escalation.
In addition to her domestic contributions, Dr. Lu has engaged in groundbreaking collaborative projects between Yale University and the Chinese National Center for Cardiovascular Diseases in Beijing. These include the Millions Persons Project that assembles remarkable population health and biomedical resources from 5 million individuals across China. Moreover, she has collaborated with the NCD Risk Factor Collaboration (NCD-RisC) on global analyses examining the impact of risk factors on the worldwide burden of cardiovascular diseases.
She has authored over 100 peer-reviewed publications, including first author articles in leading journals such as The Lancet, JAMA, Circulation, and BMJ, and her work has been cited more than 40,000 times. Dr. Lu is the recipient of the 2022 John H. Laragh Research Award of the American Journal of Hypertension for her contribution to the field of hypertension.
Appointments
Cardiovascular Medicine
Assistant ProfessorPrimaryBiomedical Informatics & Data Science
Assistant ProfessorSecondaryChronic Disease Epidemiology
Assistant ProfessorSecondary
Other Departments & Organizations
- Biomedical Informatics & Data Science
- Cardiovascular Medicine
- Center for Outcomes Research & Evaluation (CORE)
- Chronic Disease Epidemiology
- Internal Medicine
- Janeway Society
- Preventive Cardiovascular Health Program at Yale
Education & Training
- ScD
- Harvard School of Public Health, Global Health and Population (2015)
Research
Overview
Medical Subject Headings (MeSH)
ORCID
0000-0001-5264-2169- View Lab Website
Yale/YNHH Center for Outcomes Research and Evaluation (CORE)
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Harlan Krumholz, MD, SM
Erica Spatz, MD, MHS
Shiwani Mahajan, MBBS, MHS
Rohan Khera, MD, MS
Karthik Murugiah, MBBS, FACC, FSCAI
Cesar Caraballo-Cordovez, MD
Cardiovascular Diseases
Chronic Disease
Publications
2024
Effect of the COVID-19 Pandemic on Monitoring and Control of Cardiovascular Risk Factors and Disparities
Lu Y, Brush J, Liu Y, Li S, Asher J, Krumholz H. Effect of the COVID-19 Pandemic on Monitoring and Control of Cardiovascular Risk Factors and Disparities. JACC Advances 2024, 3: 101177. DOI: 10.1016/j.jacadv.2024.101177.Peer-Reviewed Original ResearchConceptsFloods and cause-specific mortality in the United States during 2001-2020
Chu L, Warren J, Spatz E, Lowe S, Lu Y, Ma X, Ross J, Krumholz H, Chen K. Floods and cause-specific mortality in the United States during 2001-2020. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.1705.Peer-Reviewed Original ResearchShort-term association between ambient ozone and onset of acute myocardial infarction of young patients: Results from the VIRGO study
Zhang S, Chu L, Lu Y, Krumholz H, Chen K. Short-term association between ambient ozone and onset of acute myocardial infarction of young patients: Results from the VIRGO study. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0539.Peer-Reviewed Original ResearchLong-term exposure to wildfire smoke PM2.5 and mortality in the contiguous United States
Ma Y, Zang E, Liu Y, Wei J, Lu Y, Krumholz H, Bell M, Chen K. Long-term exposure to wildfire smoke PM2.5 and mortality in the contiguous United States. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.1154.Peer-Reviewed Original ResearchBarriers to Optimal Clinician Guideline Adherence in Management of Markedly Elevated Blood Pressure
Lu Y, Arowojolu O, Qiu X, Liu Y, Curry L, Krumholz H. Barriers to Optimal Clinician Guideline Adherence in Management of Markedly Elevated Blood Pressure. JAMA Network Open 2024, 7: e2426135. PMID: 39106065, PMCID: PMC11304113, DOI: 10.1001/jamanetworkopen.2024.26135.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBarriers to guideline adherenceElectronic health recordsGuideline adherenceClinician adherenceEHR dataElevated blood pressureHypertension managementAnalysis of EHR dataYale New Haven Health SystemSevere hypertensionClinical practice guidelinesAdherence scenariosQualitative content analysisPublic health challengeThematic saturationHealth recordsHealth systemBlood pressureThematic analysisTargeted interventionsManagement of severe hypertensionQualitative studyHealth challengesPractice guidelinesPatient outcomesInternal tremors and vibrations in long COVID: a cross-sectional study
Zhou T, Sawano M, Arun A, Caraballo C, Michelsen T, McAlpine L, Bhattacharjee B, Lu Y, Khera R, Huang C, Warner F, Herrin J, Iwasaki A, Krumholz H. Internal tremors and vibrations in long COVID: a cross-sectional study. The American Journal Of Medicine 2024 PMID: 39069199, DOI: 10.1016/j.amjmed.2024.07.008.Peer-Reviewed Original ResearchAltmetricConceptsNew-onset conditionsInternal tremorLong COVID symptomsCOVID symptomsNon-Hispanic whitesCross-sectional studyQuality of lifeVisual analogue scaleWorse healthHealth statusStudy participantsDemographic characteristicsAnalogue scaleOutcome variablesNeurological conditionsLong COVIDMast cell disordersTreatment experienceHealthComorbiditiesSymptomsMedian agePeopleCell disordersExcess Cardiovascular Mortality Among Black Americans 2000-2022
Arun A, Sawano M, Lu Y, Warner F, Caraballo C, Khera R, Echols M, Yancy C, Krumholz H. Excess Cardiovascular Mortality Among Black Americans 2000-2022. Journal Of The American College Of Cardiology 2024, 84: 581-588. PMID: 38901531, DOI: 10.1016/j.jacc.2024.06.004.Peer-Reviewed Original ResearchCitationsAltmetricOptimal Blood Pressure Control for Optimal Longevity: Balancing Cardiovascular and Cognitive Outcomes
Lu Y, Ma Y. Optimal Blood Pressure Control for Optimal Longevity: Balancing Cardiovascular and Cognitive Outcomes. Circulation Cardiovascular Quality And Outcomes 2024, 17: e011135. PMID: 38813694, DOI: 10.1161/circoutcomes.124.011135.Peer-Reviewed Original ResearchAltmetricHypertension Trends and Disparities Over 12 Years in a Large Health System: Leveraging the Electronic Health Records
Brush J, Lu Y, Liu Y, Asher J, Li S, Sawano M, Young P, Schulz W, Anderson M, Burrows J, Krumholz H. Hypertension Trends and Disparities Over 12 Years in a Large Health System: Leveraging the Electronic Health Records. Journal Of The American Heart Association 2024, 13: e033253. PMID: 38686864, PMCID: PMC11179912, DOI: 10.1161/jaha.123.033253.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsElectronic health recordsRegional health systemImprove hypertension careHealth systemHealth recordsHypertension careDiastolic blood pressureAge-adjusted prevalence ratesNon-Hispanic Black patientsPrevalence ratesLarger health systemCross-sectional analysisTransformation of medical dataLeveraging real-world dataHigh prevalence rateHypertension trendsHypertension prevalenceBlood pressureBlood pressure measurementsHypertension diagnosisPrimary outcomeNational trendsProportion of patientsAntihypertensive medicationsBlack patientsLong COVID Characteristics and Experience: A Descriptive Study from the Yale LISTEN Research Cohort
Sawano M, Wu Y, Shah R, Zhou T, Arun A, Khosla P, Kaleem S, Vashist A, Bhattacharjee B, Ding Q, Lu Y, Caraballo C, Warner F, Huang C, Herrin J, Putrino D, Michelsen T, Fisher L, Adinig C, Iwasaki A, Krumholz H. Long COVID Characteristics and Experience: A Descriptive Study from the Yale LISTEN Research Cohort. The American Journal Of Medicine 2024 PMID: 38663793, DOI: 10.1016/j.amjmed.2024.04.015.Peer-Reviewed Original ResearchCitationsAltmetricConceptsExperiences of peopleHealth statusLong COVIDLower health statusNew-onset conditionsCommunity support servicesNon-Hispanic whitesArray of healthQuality of lifeVisual analogue scaleMental healthPsychological distressPsychological statusDescriptive studyHealthcare systemMedian scoreSupport servicesResearch cohortSocial isolationDemographic characteristicsAnalogue scaleImpact of long COVIDHealthFinancial stressParticipants
Academic Achievements and Community Involvement
activity National Institutes of Health (NIH)
Peer Review Groups and Grant Study SectionsReviewerDetails06/01/2023 - Presentactivity JACC
Journal ServiceAssociate EditorDetails02/01/2024 - Presentactivity American Heart Association
Professional OrganizationsFellowDetails07/01/2021 - Presentactivity Unraveling the Interplay between Age, Obesity, and Mortality across Adulthood: Insights from National Health and Nutrition Examination Survey 1999-2018
Poster PresentationAmerican Heart Association Scientific Sessions 2023Details11/11/2023 - 11/13/2023Philadelphia, PA, United Statesactivity Disparities in Low Cognitive Function Score and Mortality Risk Among Older Adults in the United States
Poster PresentationAmerican Heart Association Scientific Sessions 2023Details11/11/2023 - 11/13/2023Philadelphia, PA, United States
Links & Media
News
- August 08, 2024Source: MedCentral
Physicians Are Not Adhering to Severe Hypertension Care Guidelines
- July 02, 2024
Yale Faculty Members Named to JACC Editorial Board
- May 28, 2024
Next Generation Research Uses Real-World Data to Identify Most Effective Hypertension Drugs for Patients
- April 01, 2024
Yale Faculty Present Groundbreaking Clinical Research at the 2024 American College of Cardiology Scientific Sessions
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Contacts
Locations
Yale Center for Outcomes Research and Evaluation
Academic Office
195 Church Street, Rm 5th Floor
New Haven, CT 06510