VA/Yale Researchers Lead Study That Assesses Well-being of U.S. Veterans
A new study led by the National Center for PTSD and Yale researchers analyzed data from a nationally representative sample of more than 2,400 U.S. veterans to examine subjective ratings and key sociodemographic, health, and psychosocial correlates of well-being. Peter Jongho Na, MD, MPH, and Robert Pietrzak, PhD, MPH, were lead and senior authors of the study, published in JAMA Network Open.
Bile Duct Function and Disease Highlighted in New Research Study
Recent research from the Gupta Lab, led by Serrena Singh and supervised by Vikas Gupta, MD, PhD, assistant professor of medicine (digestive diseases), provides insights into the extrahepatic bile ducts. These bile ducts outside of the liver are a critical but poorly understood component of the human digestive system. This study, which was published in the journal Development Cell, marks a significant step forward in understanding diseases affecting these ducts, such as primary sclerosing cholangitis and cholangiocarcinoma.
Neural Patterns Differentiate Traumatic From Sad Autobiographical Memories in PTSD
Investigators from Yale and Mount Sinai schools of medicine studied the neural activity of 28 people diagnosed with post-traumatic stress disorder (PTSD). They found that autobiographical memories for sad and neutral memories are processed differently in the brain than for traumatic memories. The findings were published in Nature Neuroscience. The co-senior author is Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology at Yale School of Medicine.
Thalidomide Use In Gastrointestinal Bleeding
Angiodysplasia, a type of benign vascular lesion made up of dilated blood vessels, is a common source of gastrointestinal bleeding from the small intestine. A recent editorial from Yale Internal Medicine’s Loren Laine, MD, professor of medicine and chief of digestive diseases, in the New England Journal of Medicine highlights novel findings from a recent multicenter, double-blind, randomized clinical trial evaluating thalidomide in the treatment of angiodysplasia-related bleeding.
New Advanced Diagnostic Tests Lab to Perform, Interpret Clinical-grade Molecular Testing of Biomarkers
The Yale Advanced Diagnostic Tests Laboratory in the Department of Pathology, a new unit of Yale Pathology Laboratories, offers access to novel molecular tests to external users, performing and interpreting clinical grade and high-quality molecular analysis of human tissue samples.
Implicit Bias From Providers Inhibits HCV Treatment
A new study reveals significant insights into the challenges that can occur for hepatitis C virus (HCV) micro-elimination efforts in people with HIV (PWH). Due to the opioid epidemic, the prevalence of co-infection with HIV and HCV has been increasing. If left untreated, HCV infection can lead to liver damage, cancer, and death. Although HIV requires lifelong therapy, HCV can be cured with a few months of oral medications.
Yale Study Finds Genetic Links Between Some Health Conditions and PTSD
A new study led by Yale Department of Psychiatry researchers and published in JAMA Psychiatry has identified numerous physical health conditions, particularly diseases of the cardiovascular and respiratory systems, that have genetic links to post-traumatic stress disorder (PTSD). Gita Pathak, PhD, and Renato Polimanti, PhD, are first and senior authors, respectively.
Screening for Intimate Partner Violence Experience and Use in the Veterans Health Administration
A first-of-its-kind study by Yale School of Medicine researchers revealed high amounts of intimate partner violence involvement among adult patients seeking mental health services at veterans’ health care facilities in the United States.
New Yale Initiative Looks Beyond Life Span to Increase Years of Health
Aging is a major risk factor for most chronic conditions, evidence shows, yet much of current research focuses on addressing specific diseases. The new Translational Geroscience Initiative at Yale School of Medicine (YSM) seeks to change that approach by studying the effects of aging on various ailments.
Africa on the Global Stage: Analyzing 30 Years of African-Led Clinical Trials in Cardiovascular Medicine
In order to understand the limitations faced by African investigators in modern cardiology research, a group of researchers, led by Internal Medicine Resident Abdelrahman Abushouk, MD, analyzed 30 years of African-led clinical trials in cardiovascular medicine.
Pathology Office of Research Affairs Makes an Impact
Gina Della Porta, left, Director of the Office of Research Affairs, and David Stern, Professor of Pathology and Vice Chair for Basic and Translational Sciences, who oversees the office. In just one year, the Department of Pathology’s Office of Research Affairs has made an impact.
Investigators Launch Study Aimed at Accelerating Understanding of Bipolar Disorder
A multidisciplinary team of researchers based at Yale will launch a series of studies aimed at accelerating understanding of bipolar disorder and generating new and more effective treatments. Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience and Professor of Psychiatry, and in the Child Study Center and of Radiology and Biomedical Imaging, will lead the research team.
Electronic Health Record Strategies Can Improve Care of Patients with Heart Failure
Doctors frequently rely on the electronic health record (EHR) when caring for patients. Oftentimes, EHR systems will include clinical decision support tools that offer recommendations and reminders for physicians determining how to manage diagnosis or treatment plans.
Yale Older Adult Research Center Receives Renewed Funding
For the sixth consecutive time, the Yale Claude D. Pepper Older Americans Independence Center (OAIC) has been renewed for funding from the National Institute on Aging (NIA). The center is one of only two such programs nationwide that have received continuous NIA support since it was first funded in 1992.
New Outpatient Raynaud Treatment Saves Fingers and Toes
In a new outpatient treatment at Yale, epopostrenol infusions are safely given to patients whose fingers and toes are damaged by severe Raynaud phenomenon, also known as Raynaud’s phenomenon, to prevent amputation. Previously, these patients were sent to the emergency department, where they often waited for days before receiving treatment.
Montalvo-Ortiz Awarded NIDA Grant for Opioid Use Disorder Study
Janitza Montalvo-Ortiz, PhD, assistant professor of psychiatry, has been awarded a grant by the National Institute on Drug Abuse (NIDA) for the project, “Deciphering the single-nucleus genomic regulatory structure of opioid use disorder in the human brain.”