Breaking the Egg Barrier: A Sperm Story
Yale Physiology researchers found that sperm hyperactivation is an evolutionary conserved mechanism to penetrate the egg barriers, used as early as in monotreme but diverged to use it as a way of navigation in the female reproductive tract when it become more complicated in placenta mammals.
WHRY Launches Studies on Endometrial Cancer, Addiction to Opioids, and Stroke
While continuing to focus on the impacts of COVID-19, the center has enlarged its research portfolio to include new projects on the prevention of endometrial cancer in a growing cohort of women at high risk, non-opioid pain management following a cesarean section for women with opioid use disorder who are in recovery, and sex differences in stroke.
WHRY Funds Studies on Stroke, Endometrial Cancer, and Addiction to Opioids
Women’s Health Research at Yale today announced funding for three studies investigating sex differences in stroke, endometrial cancer, and alternate pain relief for women recovering from past opioid use who are giving birth via cesarean section.
Tiny Miracle: Amidst Pandemic, Connecticut's First Fetal Surgery for Spina Bifida
On March 21, the Yale Fetal Care Center team performed the state’s first fetal surgery to correct myelomeningocele, a serious form of spina bifida that has a limited correction window in an unborn child's development.
Professional Society Issues Pregnancy-related COVID Guidance Co-authored by Yale OB/GYN Professor
The International Society for Ultrasound in Obstetrics and Gynecology (ISUOG) has released a guideline on management of COVID in pregnancy. Joshua Copel, professor and vice chair of obstetrics, gynecology, and reproductive sciences—and past president of ISUOG—is a co-author.
Ravven, Budde, Among Authors of New Review on Impact of Paid Maternity Leave on Mothers, Children
Simha Ravven, MD, Assistant Clinical Professor, and Kristin Budde, MD, MPH, Assistant Professor of Clinical Psychiatry, are among the authors of a new systematic literature review that explores the impact of paid maternity leave on the mental and physical health of mothers and children.
Taylor Receives the “Distinguished Scientist Award” from Society for Reproductive Investigation for 2020
The 2020 Society for Reproductive Investigation “Distinguished Scientist Award” is given to Hugh S. Taylor, MD, chair of the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale.
The harmful effects of stress during pregnancy can last a lifetime
Mice exposed to stress in the womb and soon after birth can expect a lifetime of immune system deficiencies that hinder the ability to ward off infections and cancer, Yale University researchers report March 5 in the journal Cell.
Innovations and Discoveries on the Horizon
On the evening of November 20, Dr. Hugh Taylor welcomed just over 20 guests to an intimate event at the Boyer Center, focusing on the department’s advances for women in gynecological cancer research and infertility. It was an inspiring opportunity for all the guests to gain a more nuanced understanding of the many contributions the Department has made—and is poised to continue make—in these critical aspects of women’s health.
Yale Cancer Center Scientists Build Genomic Research Platform to Help Treat Cervical Cancer
Yale Cancer Center scientists have built a powerful genomic research platform to study cervical cancer, a disease that often is untreatable if it progresses after surgery or primary chemo-radiation treatment.
“We can get just about anybody pregnant,” said Hugh Taylor, MD, HS ’92, FW ’98, chair and the Anita O’Keeffe Young Professor of Obstetrics, Gynecology and Reproductive Sciences. This claim holds true even in situations that seemed to be impossible in the past.Source: Yale Medicine Magazine
Once-Common Hysterectomy Technique Linked to Worse Uterine Cancer Outcomes
Every year, nearly 700,000 American women have surgery to remove their uterus (hysterectomy) or uterine fibroids (myomectomy). A laparoscopic surgical technique once commonly used in these procedures could be worsening the outcomes for women who have undiagnosed uterine cancer at the time of the procedure, Yale Cancer Center scientists report in the Journal of Clinical Oncology.
Study: Accuracy of Five Self‐Report Screening Instruments for Substance Use in Pregnancy
Nearly one-fourth of pregnant women report having used alcohol, tobacco, or other substances in the past month, yet current screening questionnaires used by physicians may not accurately identify many of them. Kimberly A. Yonkers, MD, Professor of Psychiatry, of Epidemiology (Chronic Diseases) and of Obstetrics, Gynecology, and Reproductive Services at Yale School of Medicine, was the senior researcher among investigators across three universities who compared results of five commonly used questionnaires against laboratory testing.
Dr. Vikki Abrahams receives the 2019 American Society for Reproductive Immunology Award
Previously known as the Blackwell Munksgaard Award, the American Journal of Reproductive Immunology Award is presented annually to a senior investigator who has made outstanding contributions to the area of reproductive immunology. Contributions can be in the area of clinical or basic research.
Researchers Identify Stem Cell Source of Key Process in Female Reproduction
Each month during women’s reproductive years, the uterus sheds and regenerates the tissue lining its walls in preparation for a pregnancy or the next cycle. The process behind this age-old and essential part of human reproduction is not well understood. But recent research led by Yale pathologist Wang Min identifies stem cells and a gene that contribute to this monthly event.
New Stem-cell Cultivation Procedure Boosts Hope for Cures
When the Taylor lab in Yale’s Division of Reproductive Sciences extracted stem cells from human endometrial tissue—more commonly known as the uterine lining—the researchers were proud of their accomplishment. They didn’t think the find was extraordinary, and they certainly didn’t imagine that it might lead to treatments for a neurodegenerative condition. They were wrong—and happily so.