Dr. Rachel Perry Receives APS New Investigator Award
Rachel Perry, PhD, assistant professor of medicine (endocrinology) and of cellular and molecular physiology, received the Endocrinology and Metabolism Section New Investigator Award from the American Physiological Society (APS) during its summit on April 21.
Small: Yale study may help resolve bitter debate over low-cal sweeteners
Several studies in recent years have reported that low-calorie sweeteners in foods and beverages disrupt the human metabolism, promoting the development of diabetes and obesity. But other studies have found that consuming low-calorie drinks and food has little impact on metabolism and might actually aid in weight loss. A new study by Yale researchers published March 3 in the journal Cell Metabolism may help reconcile these conflicting findings.
Molecular ‘Doormen’ Open the Way to Potential Obesity Treatment
In obese individuals, cellular "doormen" open the gates far too wide in certain key fat cells, known as visceral fat cells, letting in too many carbohydrates without first burning off lipids. This leads to a ballooning of the size of visceral fat cells in the belly.
Want to Lose Weight? You Don’t Have to Do It Alone
A new Yale weight loss center aims to provide the entire continuum of care for patients with obesity, as a growing body of evidence has shown that weight loss—be it surgical or nonsurgical—also prolongs life, restores mobility, and lowers the risks of cancer, heart disease, liver disease, and other serious illnesses. “You start to get an idea of what a burden obesity is when you relieve patients of that burden. They were affected, literally, from head to toe,” says John Morton, MD, MPH.Source: Yale Medicine
Yale-led Study Reveals Biology of Leptin, the Hunger Hormone
In a new study, Yale researchers offer insight into leptin, a hormone that plays a key role in appetite, overeating, and obesity. Their findings advance knowledge about leptin and weight gain, and also suggest a potential strategy for developing future weight-loss treatments, they said.
Pain and modifiable risk factors among overweight veterans who seek to lose weight
Robin Masheb, PhD, Senior Research Scientist in Psychiatry and Director of the Veterans Initiative for Eating and Weight at the VA Connecticut Healthcare System, is the senior author of a paper published in Appetite that examines the relationship between pain and and modifiable risk factors among overweight veterans who seek to lose weight.
How obesity drives colon cancer in mice
Obesity, which is on the rise worldwide, has been linked to colon cancer but the mechanism has been a mystery. In a new study, Yale researchers and their co-authors have uncovered how obesity drives tumor growth in mice, revealing potential strategies to combat the disease.
Human insulin as safe and effective to treat type 2 diabetes as costlier insulin analogs
Patients with Type 2 diabetes who were treated with the newer generation of insulin analog drugs did not have substantially better outcomes than those treated with less costly human insulin, according to a study by Yale School of Medicine researchers and colleagues at Kaiser Permanente.
Prevalence of eating disorders taken from largest sample in the United States
Carlos Grilo, PhD, Professor of Psychiatry and of Psychology and Director of the Program for Obesity Weight and Eating Research (POWER) at Yale, is the senior author of a new study published in Biological Psychiatry that revises the outdated estimates of the prevalence of eating disorders in the United States.
Study illuminates tiny RNA’s role in heart disease, obesity
A tiny RNA molecule plays a big role in the development of two diseases affecting billions of people worldwide: heart disease and obesity. Yale researchers have found that by disrupting this microRNA in key tissues, they can reduce plaque buildup in arteries while avoiding unintended effects.
Uncovering Asthma's Genetic Origins
The statistics about asthma are staggering. According to a recent Global Burden of Disease Study, more than 334 million people worldwide may suffer from this common chronic disease. In the United States, the Centers for Disease Control and Prevention reports that asthma afflicts an estimated 25 million people, about 8 percent of the population.