Role of Nutrient May Reveal Dietary Target in Fight Against Microbial Infections
A nutrient that is common in the human diet has been found to aid the survival of a cancer-causing bacterium, a new Yale study finds. The findings could reveal an important target for new drugs to tackle numerous infectious diseases in humans.Source: Yale West Campus
Le Zhang, PhD Wins Avenir Award for Research on Substance Use Disorders and HIV/AIDS
Assistant Professor Le Zhang, PhD was recently awarded a DP2 grant from the National Institutes of Health (NIH), entitled “Immune Network Dysregulation of the Central Nervous System with HIV Persistence and Opioid Abuse.” The grant, which amounts to more than $2.5 million, began on May 15, 2022 and lasts for four years.
Celebrating 18 Years of Microbial Pathogenesis at Yale on the Occasion of Jorge Galán’s 60th Birthday
The Department of Microbial Pathogenesis is pleased to invite our colleagues and friends to attend a symposium on Oct. 14 commemorating 18 years of Microbial Pathogenesis at Yale University, being held on the occasion of Dr. Jorge Galán’s 60th birthday. Following the symposium there will be a reception open to all participants at the Peabody Museum.
Research in the news: Inflammatory immune cells can flip the genetic script
A type of immune cell that promotes inflammation during the immune response, TH17, can convert into another type of cell that reduces inflammation, Yale researchers have found. The finding, published April 29 in Nature, points to a possible therapeutic strategy for inflammation-mediated diseases, such as inflammatory bowel disease, multiple sclerosis, and rheumatoid arthritis.
Dr. David Hafler appointed the inaugural Edgerly Professor of Neurology
Dr. David A. Hafler, newly appointed as the inaugural William S. and Lois Stiles Edgerly Professor of Neurology, is a clinical scientist whose research focuses on understanding the mechanism of autoimmunity with a particular interest in inflammatory central nervous system diseases. The William S. and Lois Stiles Edgerly Professorship was established by William S. Edgerly and his wife, Lois Stiles Edgerly, who are committed to the support of research in the field of multiple sclerosis in the DepSource: YaleNews
Research in the news: Yale team uncovers genetic trigger for immune response
The thousands of mitochondrial DNA (mtDNA) molecules present in each cell are known primarily for their role converting food and oxygen into energy. But Yale researchers have identified an unexpected relationship between mtDNA and the innate immune response.
Infant’s mysterious death leads to discovery of a family disease
Shortly after the death of his newborn son, 43-year-old Erik Drewniak was hospitalized with some of the same symptoms that killed the infant — high fever, severe respiratory distress, and hemorrhaging in the lungs, intestines, and brain.
Yale study identifies potential bacterial drivers of inflammatory bowel disease
Yale University researchers have identified a handful of bacterial culprits that may drive inflammatory bowel diseases (IBD) such as Crohn’s disease and ulcerative colitis, using patients’ own intestinal immune responses as a guide.
Controlling the triggers of age-related inflammation could extend ‘healthspan’
Inflammation is the common denominator of many chronic age-related diseases such as arthritis, gout, Alzheimer’s, and diabetes. But according to a Yale School of Medicine study, even in the absence of a disease, inflammation can lead to serious loss of function throughout the body, reducing healthspan — that portion of our lives spent relatively free of serious illness and disability.