New Outpatient Raynaud Treatment Saves Fingers and Toes
In a new outpatient treatment at Yale, epopostrenol infusions are safely given to patients whose fingers and toes are damaged by severe Raynaud phenomenon, also known as Raynaud’s phenomenon, to prevent amputation. Previously, these patients were sent to the emergency department, where they often waited for days before receiving treatment.
New Cell Therapy Program to Offer Advanced Cell-based Treatment for Patients With Severe Lupus
A new technology called chimeric antigen receptor (CAR) T-cell therapy has been successfully used to treat patients with cancer. Fotios Koumpouras, MD, Nathan Johnson, MD, PhD, and Marwin Groener, MD, are working to apply this novel branch of science to help patients with lupus.
Large Gift Establishes Colton Center for Autoimmunity at Yale School of Medicine
Philanthropists Judith and Stewart Colton have donated a major gift to establish the Colton Center for Autoimmunity at Yale, under the direction of Joseph E. Craft, MD, Paul B. Beeson Professor of Medicine and professor of immunobiology.
Better Science, Better Lives: Women's Health Research at Yale is Working for You
Across the country, it’s becoming clearer every day: We must study the health of women. We must study the influence of sex-and-gender differences on health. And it’s time for all aspects of medical research and practice to embrace this change.
The enemy within: Gut bacteria drive autoimmune disease
Bacteria found in the small intestines of mice and humans can travel to other organs and trigger an autoimmune response, according to a new Yale study. The researchers also found that the autoimmune reaction can be suppressed with an antibiotic or vaccine designed to target the bacteria, they said.
Chaos, hope, and the lupus butterfly theory
Yale researchers believe some antibodies associated with lupus may be sources of both chaos and hope in cancer. Borrowing from the Greek legend of Pandora’s box and chaos theory by calling it the “lupus butterfly theory,” the idea was described recently in the journal Nature Reviews Rheumatology.
From the Gut: How Beneficial Bacteria Inside Our Bodies Might Trigger and Treat Autoimmune Disease
Two years after obtaining a Women’s Health Research at Yale seed grant, Dr. Martin Kriegel has continued exploring how beneficial bacteria that live in the gut might trick the body into an autoimmune reaction known as antiphospholipid syndrome.
Research in the news: Suppressing the immune response may lead to more potent vaccines, a study finds
Yale researchers uncovered a new role for a type of immune cell, known as regulatory T cells, in promoting long-term immunity. The new insight gets researchers one step closer to developing vaccines that could be more protective against some of the most intractable viral infections, including HIV and flu.
Spotlight on Clinical Research: May is Lupus Awareness Month
Lupus is a lifelong chronic disease in which the body’s immune system attacks healthy cells and tissue. This can cause damage to skin, joints, kidneys and other organs throughout the body. Anyone can get lupus, but it most often affects women and is also more common in women of African American, Hispanic and Asian descent.
Women's Health Research at Yale: 2013 Pilot Project Awards Announced
This year’s content areas include breast cancer, the second leading cause of cancer deaths in women; autoimmune diseases, more common in women than men, including antiphospholipid syndrome, (or APS), which can cause stroke, heart attack and pregnancy-related problems, and lupus; HIV prevention, as HIV is far more prevalent among young black women than other young women, and sexually transmitted infections that affect more women than men and currently have no cure or intervention to prevent recur
Sang Taek Kim Returns to YSM to Lead Immunotherapy Adverse Events Program
A physician scientist, Sang Taek Kim, MD, PhD, assistant professor of medicine (rheumatology), is interested in the autoimmune complications induced by cancer immunotherapy. In his new role, he serves as director of the Immunotherapy Adverse Events in Rheumatology Program.
Philanthropist Nancy Davis Opens Up About Life with Multiple Sclerosis and Her Mission to Help Others
Philanthropist Nancy Davis tells her story of living with multiple sclerosis, from her diagnosis after a ski accident to how she eventually found the treatment plan that was right for her. Yale Neurology Chair David Hafler, MD also speaks about how far research into the autoimmune disease has come and what the most effective treatment strategies are.Source: People