Michael Bloch, MD, MS

Associate Professor in the Child Study Center; Associate Director, Albert J. Solnit Integrated Training Program; Associate Director of the Tic and OCD Program

Research Departments & Organizations

Child Study Center: Tic Disorder & Obsessive Compulsive Disorder Program

Clinical Neuroscience Research Unit

Neuroscience Research Training Program (NRTP)

Obsessive Compulsive Disorder Research Clinic

Office of Cooperative Research

Research Interests

Child Psychiatry; Meta-Analysis; Neuroimaging; Obsessive-Compulsive Disorder; Psychiatry and Psychology; Tourette Syndrome; Trichotillomania

Research Summary

Michael H. Bloch's research interests focus on studying Tourette syndrome (TS), Obsessive-compulsive disorder (OCD) and Trichotillomania (TTM) across the lifespan. His research focuses on developing better treatments for children and adults with these conditions and examining predictors of long-term outcome with an emphasis on neuroimaging.

Specialized Terms: Tourette syndrome; Obsessive-compulsive disorder; Trichotillomania

Extensive Research Description

Double-Blind, Placebo-Controlled Trial of N-acetylcysteine for Pediatric Trichotillomania, OCD and Tourette Syndrome

Neuroimaging Study of Adulthood Outcome in Children with Tourette Syndrome

Functional Neuroimaging Study of Response to an NMDA-Receptor Antagonist in Treatment-Refractory OCD

Clinical Trials

Conditions Study Title
Child Development & Autism, Diseases of the Nervous System, Genetics - Adult, Genetics - Pediatric, Mental Health & Behavioral Research Genetic and molecular studies of developmental neuropsychiatric disorders
Children's Health, Genetics - Pediatric AFQ056 for Language Learning in Children With FXS
Diseases of the Nervous System, Mental Health & Behavioral Research Examination of Glutamate and mGluR5 in Psychiatric Disorders
Children's Health, Mental Health & Behavioral Research Open-Label Safety and Tolerability Study of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Syndrome
Mental Health & Behavioral Research Ketamine in Borderline Personality Disorder
Mental Health & Behavioral Research Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide
Mental Health & Behavioral Research Evaluation of glutamate levels in adolescent mood disorders
Diseases of the Nervous System, Genetics - Adult, Genetics - Pediatric, Mental Health & Behavioral Research Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)
Mental Health & Behavioral Research Imaging SV2A in mood disorders
Diseases of the Nervous System, Mental Health & Behavioral Research Biomarkers of Clinical Subtype and Treatment Response in Obsessive-Compulsive Disorder
Children's Health, Mental Health & Behavioral Research Ketamine Infusion for Adolescent Depression
Diseases of the Nervous System, Mental Health & Behavioral Research Neurofeedback for Obsessive-Compulsive Disorder
Addictive Behaviors PET Imaging of mGLuR5 With Drug Challenge
Mental Health & Behavioral Research, Tobacco Addiction Acetylcholine, Tobacco Smoking, Genes and Nicotinic Receptors (nic_physo)

Selected Publications

  • Trichotillomania across the life span.

    Bloch MH. Trichotillomania across the life span. Journal Of The American Academy Of Child And Adolescent Psychiatry 2009, 48:879-83. 2009

  • Predictors of early adult outcomes in pediatric-onset obsessive-compulsive disorder.

    Bloch MH, Craiglow BG, Landeros-Weisenberger A, Dombrowski PA, Panza KE, Peterson BS, Leckman JF. Predictors of early adult outcomes in pediatric-onset obsessive-compulsive disorder. Pediatrics 2009, 124:1085-93. 2009

  • Meta-analysis of the symptom structure of obsessive-compulsive disorder.

    Bloch MH, Landeros-Weisenberger A, Rosario MC, Pittenger C, Leckman JF. Meta-analysis of the symptom structure of obsessive-compulsive disorder. The American Journal Of Psychiatry 2008, 165:1532-42. 2008

  • Systematic Review: Antipsychotic Augmentation for Treatment-Resistant Obsessive-Compulsive Disorder

    Bloch MH, Landeros-Weisenberger A, Kelmendi BK, Coric V, Bracken MB, Leckman JF. Systematic Review: Antipsychotic Augmentation for Treatment-Resistant Obsessive-Compulsive Disorder. Molecular Psychiatry 2006; 11: 622-632. 2006

  • Meta-analysis: treatment of attention-deficit/hyperactivity disorder in children with comorbid tic disorders.

    Bloch MH, Panza KE, Landeros-Weisenberger A, Leckman JF. Meta-analysis: treatment of attention-deficit/hyperactivity disorder in children with comorbid tic disorders. Journal Of The American Academy Of Child And Adolescent Psychiatry 2009, 48:884-93. 2009

  • Basal Ganglia Volumes and Future Tic Severity in Children with Tourette Syndrome

    Bloch MH, Leckman JF, Zhu H, Peterson BS. Basal Ganglia Volumes and Future Tic Severity in Children with Tourette Syndrome – Neurology 2005; 65:1253-8. 2005

See list of PubMed publications

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