Gilbert Moeckel, MD, PhD, FASN

Professor of Pathology; Director of Mentoring Program, Pathology; Director, Renal, Cardiac & Transplant Pathology and Electron Microscopy Laboratory, Pathology; Director, Renal & Genitourinary Fellowship Program, Pathology

Research Departments & Organizations

Pathology: Moeckel Lab | Pathology Research

Office of Cooperative Research

Research Interests

Acute Kidney Injury; Diabetic Nephropathies; Fibrosis; Kidney Failure, Chronic; Stem Cell Niche

Research Summary

My lab studies the molecular mechanisms of acute kidney injury and tubular cell regeneration and the role of adult stem cells in repair of acute kidney injury. Moreover, the lab studies the underlying factors that lead to progression of fibrosis in diabetic nephropathy.

Extensive Research Description

The following projects are currently ongoing in the Moeckel lab:

1. Role of DDT/MIF2 in acute tubular injury repair and regeneration

2. Role of intrinsic progenitor cells/pericytes in tubular injury repair

3. Epigenetic mechanisms of Diabetic Nephropathy progression

4. Role of inorganic phosphate in vascular stiffness

5. Aldosterone-dependent mechanisms of fibronectin synthesis in kidney fibroblasts.

Activities

  • Granulomatous Interstitial Nephritis Bangkok, Thailand (2014 - 2014)

Selected Publications

See list of PubMed publications

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Contact Info

Gilbert Moeckel, MD, PhD, FASN
Lab Location
Renal Pathology LboratoryBrady Memorial Laboratory
310 Cedar Street, Ste LB20

New Haven, CT 06510
Office Location
Department of PathologyBrady Memorial Laboratory
310 Cedar Street, Ste LB20

New Haven, CT 06510
Mailing Address
310 Cedar Street
PO Box 208023

New Haven, CT 06520-8023

Curriculum Vitae

Moeckel Lab

Glomerulonephritis

This image shows a necrotizing lesion in a human glomerulus, which is the main filtration structure in the kidney. These lesions need to be treated promptly or the patient may loose all kidney function.