DownloadHi-Res Photo

William Chang, MD, PhD

Assistant Professor of Medicine (Nephrology)

Research & Publications
Biography
News

Coauthors

Selected Publications

Differential functional roles of fibroblasts and pericytes in the formation of tissue-engineered microvascular networks in vitroKosyakova N, Kao DD, Figetakis M, López-Giráldez F, Spindler S, Graham M, James KJ, Won Shin J, Liu X, Tietjen GT, Pober JS, Chang WG. Differential functional roles of fibroblasts and pericytes in the formation of tissue-engineered microvascular networks in vitro Npj Regenerative Medicine 2020, 5: 1. PMID: 31934351, PMCID: PMC6944695, DOI: 10.1038/s41536-019-0086-3.
NSAID associated bilateral renal infarctions: a case reportJeon Y, Lis JB, Chang WG. NSAID associated bilateral renal infarctions: a case report International Journal Of Nephrology And Renovascular Disease 2019, 12: 177-181. PMID: 31447577, PMCID: PMC6682756, DOI: 10.2147/ijnrd.s212010.
Tools for Kidney Tissue Engineering: Bioreactor Systems, Scaffolds, and Cell SourcesChang WG. (2019). Tools for Kidney Tissue Engineering: Bioreactor Systems, Scaffolds, and Cell Sources. In R. L. Reis, & M. E. Gomes (Eds.), Encyclopedia of Tissue Engineering and Regenerative Medicine, Vol. 1 (pp. 199–208). Academic Press: Elsevier.
A short discourse on vascular tissue engineeringChang WG, Niklason LE. A short discourse on vascular tissue engineering Npj Regenerative Medicine 2017, 2: 7. PMID: 29057097, PMCID: PMC5649630, DOI: 10.1038/s41536-017-0011-6.
ISL1 cardiovascular progenitor cells for cardiac repair after myocardial infarctionBartulos O, Zhuang ZW, Huang Y, Mikush N, Suh C, Bregasi A, Wang L, Chang W, Krause DS, Young LH, Pober JS, Qyang Y. ISL1 cardiovascular progenitor cells for cardiac repair after myocardial infarction JCI Insight 2016, 1: e80920. PMID: 27525311, PMCID: PMC4982472, DOI: 10.1172/jci.insight.80920.
Blocking MHC class II on human endothelium mitigates acute rejectionAbrahimi P, Qin L, Chang WG, Bothwell AL, Tellides G, Saltzman WM, Pober JS. Blocking MHC class II on human endothelium mitigates acute rejection JCI Insight 2016, 1: e85293. PMID: 26900601, PMCID: PMC4756651, DOI: 10.1172/jci.insight.85293.
Tissue-Engineered Microvasculature to Reperfuse Isolated Renal GlomeruliChang WG, Fornoni A, Tietjen G, Mendez JJ, Niklason LE, Saltzman WM, Pober JS. Tissue-Engineered Microvasculature to Reperfuse Isolated Renal Glomeruli Tissue Engineering Part A 2015, 21: 2673-2679. PMID: 26414101, PMCID: PMC4652181, DOI: 10.1089/ten.tea.2015.0060.
Efficient Gene Disruption in Cultured Primary Human Endothelial Cells by CRISPR/Cas9Abrahimi P, Chang WG, Kluger MS, Qyang Y, Tellides G, Saltzman WM, Pober JS. Efficient Gene Disruption in Cultured Primary Human Endothelial Cells by CRISPR/Cas9 Circulation Research 2015, 117: 121-128. PMID: 25940550, PMCID: PMC4490936, DOI: 10.1161/circresaha.117.306290.
Sustained delivery of proangiogenic microRNA‐132 by nanoparticle transfection improves endothelial cell transplantationDevalliere J, Chang WG, Andrejecsk JW, Abrahimi P, Cheng CJ, Jane‐wit D, Saltzman WM, Pober JS. Sustained delivery of proangiogenic microRNA‐132 by nanoparticle transfection improves endothelial cell transplantation The FASEB Journal 2013, 28: 908-922. PMID: 24221087, PMCID: PMC3898640, DOI: 10.1096/fj.13-238527.
Pericytes modulate endothelial sproutingChang WG, Andrejecsk JW, Kluger MS, Saltzman WM, Pober JS. Pericytes modulate endothelial sprouting Cardiovascular Research 2013, 100: 492-500. PMID: 24042014, PMCID: PMC3826704, DOI: 10.1093/cvr/cvt215.
Paracrine exchanges of molecular signals between alginate-encapsulated pericytes and freely suspended endothelial cells within a 3D protein gelAndrejecsk JW, Cui J, Chang WG, Devalliere J, Pober JS, Saltzman WM. Paracrine exchanges of molecular signals between alginate-encapsulated pericytes and freely suspended endothelial cells within a 3D protein gel Biomaterials 2013, 34: 8899-8908. PMID: 23973174, PMCID: PMC3839675, DOI: 10.1016/j.biomaterials.2013.08.008.
In vitro Self-Assembly of Human Pericyte-Supported Endothelial Microvessels in Three-Dimensional Coculture: A Simple Model for Interrogating Endothelial-Pericyte InteractionsWaters JP, Kluger MS, Graham M, Chang WG, Bradley JR, Pober JS. In vitro Self-Assembly of Human Pericyte-Supported Endothelial Microvessels in Three-Dimensional Coculture: A Simple Model for Interrogating Endothelial-Pericyte Interactions Journal Of Vascular Research 2013, 50: 324-331. PMID: 23860328, PMCID: PMC3879598, DOI: 10.1159/000353303.
Controlled protein delivery in the generation of microvascular networksAndrejecsk JW, Chang WG, Pober JS, Saltzman WM. Controlled protein delivery in the generation of microvascular networks Drug Delivery And Translational Research 2012, 5: 75-88. PMID: 25767747, PMCID: PMC4354697, DOI: 10.1007/s13346-012-0122-y.
GDP-Mannose-4,6-Dehydratase Is a Cytosolic Partner of Tankyrase 1 That Inhibits Its Poly(ADP-Ribose) Polymerase ActivityBisht KK, Dudognon C, Chang WG, Sokol ES, Ramirez A, Smith S. GDP-Mannose-4,6-Dehydratase Is a Cytosolic Partner of Tankyrase 1 That Inhibits Its Poly(ADP-Ribose) Polymerase Activity Molecular And Cellular Biology 2012, 32: 3044-3053. PMID: 22645305, PMCID: PMC3434517, DOI: 10.1128/mcb.00258-12.
Protein requirements for sister telomere association in human cellsCanudas S, Houghtaling BR, Kim JY, Dynek JN, Chang WG, Smith S. Protein requirements for sister telomere association in human cells The EMBO Journal 2007, 26: 4867-4878. PMID: 17962804, PMCID: PMC2099466, DOI: 10.1038/sj.emboj.7601903.
NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosisChang W, Dynek JN, Smith S. NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis Biochemical Journal 2005, 391: 177-184. PMID: 16076287, PMCID: PMC1276914, DOI: 10.1042/bj20050885.
Impact of E1a modifications on tumor-selective adenoviral replication and toxicity.Sauthoff H, Pipiya T, Heitner S, Chen S, Bleck B, Reibman J, Chang W, Norman RG, Rom WN, Hay JG. Impact of E1a modifications on tumor-selective adenoviral replication and toxicity. Molecular Therapy : The Journal Of The American Society Of Gene Therapy 2004, 10: 749-57. PMID: 15451459, DOI: 10.1016/j.ymthe.2004.07.014.
A Dynamic Molecular Link between the Telomere Length Regulator TRF1 and the Chromosome End Protector TRF2Houghtaling BR, Cuttonaro L, Chang W, Smith S. A Dynamic Molecular Link between the Telomere Length Regulator TRF1 and the Chromosome End Protector TRF2 Current Biology 2004, 14: 1621-1631. PMID: 15380063, DOI: 10.1016/j.cub.2004.08.052.
TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeresChang W, Dynek JN, Smith S. TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres Genes & Development 2003, 17: 1328-1333. PMID: 12782650, PMCID: PMC196064, DOI: 10.1101/gad.1077103.
Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human TelomeresCook BD, Dynek JN, Chang W, Shostak G, Smith S. Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres Molecular And Cellular Biology 2002, 22: 332-342. PMID: 11739745, PMCID: PMC134233, DOI: 10.1128/mcb.22.1.332-342.2002.
The Vibrio cholerae O139 Calcutta bacteriophage CTXphi is infectious and encodes a novel repressor.Davis B, Kimsey H, Chang W, Waldor M. The Vibrio cholerae O139 Calcutta bacteriophage CTXphi is infectious and encodes a novel repressor. Journal Of Bacteriology 1999, 181: 6779-87. PMID: 10542181, PMCID: PMC94144, DOI: 10.1128/jb.181.21.6779-6787.1999.

Edit Profile

William Chang, MD, PhD

Contact Information

Mailing Address

Research & Publications

Biography

News

Coauthors

Selected Publications