Shenping Wu
Research Scientist in Pharmacology
Research & Publications
Biography
News
Coauthors
Selected Publications
- How to correct relative voxel scale factors for calculations of vector-difference Fourier maps in cryo-EMWang J, Liu J, Gisriel CJ, Wu S, Maschietto F, Flesher DA, Lolis E, Lisi GP, Brudvig GW, Xiong Y, Batista VS. How to correct relative voxel scale factors for calculations of vector-difference Fourier maps in cryo-EM. Journal Of Structural Biology 2022, 214: 107902. PMID: 36202310, PMCID: PMC10226527, DOI: 10.1016/j.jsb.2022.107902.
- Structural Studies αvβ8 Integrin by Single Particle Cryo-EMCampbell M, Cormier A, Ito S, Wu S, Lou J, Marks J, Baron J, Nishimura S, Cheng Y. Structural Studies αvβ8 Integrin by Single Particle Cryo-EM. Microscopy And Microanalysis 2019, 25: 1312-1313. DOI: 10.1017/s1431927619007293.
- Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosomeArmache J, Gamarra N, Johnson S, Leonard J, Wu S, Narlikar G, Cheng Y. Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome. ELife 2019, 8: e46057. PMID: 31210637, PMCID: PMC6611695, DOI: 10.7554/elife.46057.
- Cryo-EM structure of the Mechanotransduction Channel NOMPCJin P, Bulkley D, Guo Y, Zhang W, Guo Z, Huynh W, Wu S, Meltzer S, Cheng T, Jan L, Jan Y, Cheng Y. Cryo-EM structure of the Mechanotransduction Channel NOMPC. Biophysical Journal 2018, 114: 22a. DOI: 10.1016/j.bpj.2017.11.164.
- Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporterKim J, Wu S, Tomasiak T, Mergel C, Winter M, Stiller S, Robles-Colmanares Y, Stroud R, Tampé R, Craik C, Cheng Y. Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter. Nature 2014, 517: 396-400. PMID: 25363761, PMCID: PMC4372080, DOI: 10.1038/nature13872.
- Structural Studies of the Yeast Prp8-Snu114 ComplexHe Y, Wu S, Booth D, Agarrd D, Cheng Y, Guthrie C. Structural Studies of the Yeast Prp8-Snu114 Complex. Biophysical Journal 2014, 106: 47a. DOI: 10.1016/j.bpj.2013.11.338.
- The Mechanism of Nucleosome Spacing by a Dimeric Chromatin Remodeling EnzymeLeonard J, Armache J, Naber N, Wu S, Pate E, Cooke R, Cheng Y, Narlikar G. The Mechanism of Nucleosome Spacing by a Dimeric Chromatin Remodeling Enzyme. Biophysical Journal 2014, 106: 69a-70a. DOI: 10.1016/j.bpj.2013.11.461.
- Mechanistic Analysis of HP1 heterochromatin assemblyNarlikar G, Canzio D, Liao M, Naber N, Pate E, Larson A, Wu S, Cooke R, Schuck P, Cheng Y. Mechanistic Analysis of HP1 heterochromatin assembly. The FASEB Journal 2013, 27: 456.3-456.3. DOI: 10.1096/fasebj.27.1_supplement.456.3.
- A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assemblyCanzio D, Liao M, Naber N, Pate E, Larson A, Wu S, Marina D, Garcia J, Madhani H, Cooke R, Schuck P, Cheng Y, Narlikar G. A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly. Nature 2013, 496: 377-381. PMID: 23485968, PMCID: PMC3907283, DOI: 10.1038/nature12032.
- Electron Tomography of Paracrystalline 2D ArraysWinkler H, Wu S, Taylor K. Electron Tomography of Paracrystalline 2D Arrays. 2012, 955: 427-460. PMID: 23132074, PMCID: PMC7032944, DOI: 10.1007/978-1-62703-176-9_23.
- Self-Assembly of Filamentous Amelogenin Requires Calcium and Phosphate: From Dimers via Nanoribbons to FibrilsMartinez-Avila O, Wu S, Kim S, Cheng Y, Khan F, Samudrala R, Sali A, Horst J, Habelitz S. Self-Assembly of Filamentous Amelogenin Requires Calcium and Phosphate: From Dimers via Nanoribbons to Fibrils. Biomacromolecules 2012, 13: 3494-3502. PMID: 22974364, PMCID: PMC3496023, DOI: 10.1021/bm300942c.
- Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped following a Mechanical PerturbationWu S, Liu J, Reedy MC, Perz-Edwards RJ, Tregear RT, Winkler H, Franzini-Armstrong C, Sasaki H, Lucaveche C, Goldman YE, Reedy MK, Taylor KA. Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped following a Mechanical Perturbation. PLOS ONE 2012, 7: e39422. PMID: 22761792, PMCID: PMC3382574, DOI: 10.1371/journal.pone.0039422.
- Fabs Enable Single Particle cryoEM Studies of Small ProteinsWu S, Avila-Sakar A, Kim J, Booth D, Greenberg C, Rossi A, Liao M, Li X, Alian A, Griner S, Juge N, Yu Y, Mergel C, Chaparro-Riggers J, Strop P, Tampé R, Edwards R, Stroud R, Craik C, Cheng Y. Fabs Enable Single Particle cryoEM Studies of Small Proteins. Structure 2012, 20: 582-592. PMID: 22483106, PMCID: PMC3322386, DOI: 10.1016/j.str.2012.02.017.
- Self‐assembly of amelogenin proteins at the water–oil interfaceMartinez‐Avila O, Wu S, Cheng Y, Lee R, Khan F, Habelitz S. Self‐assembly of amelogenin proteins at the water–oil interface. European Journal Of Oral Sciences 2011, 119: 75-82. PMID: 22243231, PMCID: PMC6339812, DOI: 10.1111/j.1600-0722.2011.00907.x.
- Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical TransientWu S, Liu J, Reedy M, Tregear R, Winkler H, Franzini-Armstrong C, Lucaveche C, Sasaki H, Goldman Y, Reedy M, Taylor K. Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Transient. Biophysical Journal 2011, 100: 12a. DOI: 10.1016/j.bpj.2010.12.274.
- Self-aligning amelogenin nanoribbons in oil–water systemHe X, Wu S, Martinez-Avila O, Cheng Y, Habelitz S. Self-aligning amelogenin nanoribbons in oil–water system. Journal Of Structural Biology 2010, 174: 203-212. PMID: 21134461, PMCID: PMC3204882, DOI: 10.1016/j.jsb.2010.11.027.
- Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin InteractionsWu S, Liu J, Reedy MC, Tregear RT, Winkler H, Franzini-Armstrong C, Sasaki H, Lucaveche C, Goldman YE, Reedy MK, Taylor KA. Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions. PLOS ONE 2010, 5: e12643. PMID: 20844746, PMCID: PMC2936580, DOI: 10.1371/journal.pone.0012643.
- Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin InteractionsWu S, Liu J, Reedy M, Winkler H, Tregear R, Lucaveche C, Franzini-Armstrong C, Sasaki H, Goldman Y, Reedy M, Taylor K. Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions. Biophysical Journal 2010, 98: 216a. DOI: 10.1016/j.bpj.2009.12.1166.
- Methods for identifying and averaging variable molecular conformations in tomograms of actively contracting insect flight muscleWu S, Liu J, Reedy MC, Winkler H, Reedy MK, Taylor KA. Methods for identifying and averaging variable molecular conformations in tomograms of actively contracting insect flight muscle. Journal Of Structural Biology 2009, 168: 485-502. PMID: 19698791, PMCID: PMC2805068, DOI: 10.1016/j.jsb.2009.08.007.
- Multivariate Data Analysis of Repeat Volumes from Tomograms of Quick-Frozen Ca2+-activated Isometrically Contracting Insect Flight Muscle Reveals Unconventional Cross-Bridge ConformationsWU S, Reedy M, Winkler H, Goldman Y, Reedy M, Taylor K. Multivariate Data Analysis of Repeat Volumes from Tomograms of Quick-Frozen Ca2+-activated Isometrically Contracting Insect Flight Muscle Reveals Unconventional Cross-Bridge Conformations. Microscopy And Microanalysis 2007, 13: 368-369. DOI: 10.1017/s1431927607072029.
- Imaging Actomyosin In SituTaylor K, Wu S, Reedy M, Reedy M. Imaging Actomyosin In Situ. 2007, 79: 321-368. PMID: 17327163, DOI: 10.1016/s0091-679x(06)79013-6.
- Electron Tomography of Swollen Rigor Fibers of Insect Flight Muscle Reveals a Short and Variably Angled S2 DomainLiu J, Wu S, Reedy MC, Winkler H, Lucaveche C, Cheng Y, Reedy MK, Taylor KA. Electron Tomography of Swollen Rigor Fibers of Insect Flight Muscle Reveals a Short and Variably Angled S2 Domain. Journal Of Molecular Biology 2006, 362: 844-860. PMID: 16949613, DOI: 10.1016/j.jmb.2006.07.084.