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Roel Verhaak, PhD

Harvey and Kate Cushing Professor of Neurosurgery; Professor, Department of Neurosurgery

Contact Information

Roel Verhaak, PhD

Lab Location

Research Summary

We are a cancer biology lab with a research focus on brain tumors and gliomas/glioblastomas in particular. We study the processes of glioma-related tumor evolution and treatment resistance. We use high-throughput sequencing, computational analysis and functional studies in our research. We have previously identified extrachromosomal oncogene DNA amplifications as playing a particularly important role in tumor evolution of not just gliomas, but all cancers. We are developing new therapies for cancer through targeting of extrachromosomal DNA amplifications.


Research Interests

Astrocytoma; Glioblastoma; Oligodendroglioma; Diffuse Intrinsic Pontine Glioma

Public Health Interests

Cancer; Genetics, Genomics, Epigenetics

Selected Publications