Robert Makuch, PhD

• A. David Paltiel
• Benjamin Bunney
• Benjamin Toll
• Cassius Iyad Ochoa Chaar
• Charles Duncan
• E. Leon Kier
• Edward Perry
• Eliza Myers
• Gail D'Onofrio
• Guadalupe Garcia-Tsao
• John Elsworth
• Joseph Piepmeier
• Kathryn Hawk
• Lawrence Staib
• Lisa Fucito
• Marney White
• Michael Schwartz
• Nallakkandi Rajeevan
• Ralitza Gueorguieva
• Vincent DeVita
• Walter Kernan

Infant, Premature; Public Health; Smoking Cessation; Clinical Trials, Phase IV as Topic; Biostatistics

Maternal & Child Health; Regulatory Affairs; Pharmacoepidemiology

• Association of exposure to ambient particulate matter with maternal thyroid function in early pregnancy.Zhang X, Huels A, Makuch R, Zhou A, Zheng T, Xia W, Gaskins A, Makuch J, Zhu Z, Zhu C, Qian Z, Xu S, Li Y. Association of exposure to ambient particulate matter with maternal thyroid function in early pregnancy. Environmental Research 2022, 214: 113942. PMID: 35870505, DOI: 10.1016/j.envres.2022.113942.
• Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm InfantsPeterson B, Vohr B, Staib L, Cannistraci C, Dolberg A, Schneider K, Katz K, Westerveld M, Sparrow S, Anderson A, Duncan C, Makuch R, Gore J, Ment L. Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants. 2022, 215-223. DOI: 10.4324/9780203822937-21.
• Emergency Use Authorization for Remdesivir and Its Potential ImplicationsOchoa Chaar CI, Makuch R. Emergency Use Authorization for Remdesivir and Its Potential Implications. Therapeutic Innovation & Regulatory Science 2020, 55: 270-271. PMID: 32880853, PMCID: PMC7471551, DOI: 10.1007/s43441-020-00212-5.
• Ability to Reach Low-Income Smokers Enrolled in a Randomised Controlled Trial Varies with Time of MonthHawk K, Shi R, Weiss J, Makuch R, Toll B, Bernstein SL. Ability to Reach Low-Income Smokers Enrolled in a Randomised Controlled Trial Varies with Time of Month. The Journal Of Smoking Cessation 2017, 13: 227-232. PMID: 31452822, PMCID: PMC6709708, DOI: 10.1017/jsc.2017.23.
• Statistical Issues in Drug Research and DevelopmentMakuch R, Pledger G, Hall D, Herson J, Hsu J. Statistical Issues in Drug Research and Development. 2017, 225-262. DOI: 10.1201/9780203738610-5.
• Prognostic Implications of Stage of Disease and Sites of Metastases in Patients with Small Cell Carcinoma of the Lung Treated with Intensive Combination Chemotherapy1,2Ihde D, Makuch R, Carney D, Bunn P, Cohen M, Matthews M, Minna J. Prognostic Implications of Stage of Disease and Sites of Metastases in Patients with Small Cell Carcinoma of the Lung Treated with Intensive Combination Chemotherapy1,2. 2015 DOI: 10.1164/arrd.1981.123.5.500.
• Successful Tobacco Dependence Treatment in Low-Income Emergency Department Patients: A Randomized TrialBernstein SL, D’Onofrio G, Rosner J, O’Malley S, Makuch R, Busch S, Pantalon MV, Toll B. Successful Tobacco Dependence Treatment in Low-Income Emergency Department Patients: A Randomized Trial. Annals Of Emergency Medicine 2015, 66: 140-147. PMID: 25920384, PMCID: PMC4819432, DOI: 10.1016/j.annemergmed.2015.03.030.
• Selection of the treatment effect for sample size determination in a superiority clinical trial using a hybrid classical and Bayesian procedureCiarleglio MM, Arendt CD, Makuch RW, Peduzzi PN. Selection of the treatment effect for sample size determination in a superiority clinical trial using a hybrid classical and Bayesian procedure. Contemporary Clinical Trials 2015, 41: 160-171. PMID: 25583273, DOI: 10.1016/j.cct.2015.01.002.
• Comparison of Drug Approvals in Europe Versus the United StatesMakuch RW, Shi R. Comparison of Drug Approvals in Europe Versus the United States. Therapeutic Innovation & Regulatory Science 2014, 48: 362-366. PMID: 30235531, DOI: 10.1177/2168479013517103.
• How Do Perceptions About Cessation Outcomes Moderate the Effectiveness of a Gain-Framed Smoking Cessation Telephone Counseling Intervention?Latimer-Cheung AE, Fucito LM, Carlin-Menter S, Rodriguez J, Raymond L, Salovey P, Makuch R, Cummings KM, Toll BA. How Do Perceptions About Cessation Outcomes Moderate the Effectiveness of a Gain-Framed Smoking Cessation Telephone Counseling Intervention? Journal Of Health Communication 2012, 17: 1081-1098. PMID: 22765277, PMCID: PMC3644974, DOI: 10.1080/10810730.2012.665420.
• Preterm birth results in alterations in neural connectivity at age 16 yearsMullen KM, Vohr BR, Katz KH, Schneider KC, Lacadie C, Hampson M, Makuch RW, Reiss AL, Constable RT, Ment LR. Preterm birth results in alterations in neural connectivity at age 16 years. NeuroImage 2010, 54: 2563-2570. PMID: 21073965, PMCID: PMC3020252, DOI: 10.1016/j.neuroimage.2010.11.019.
• Nicotine dependence as a moderator of a quitline-based message framing interventionFucito LM, Latimer AE, Carlin-Menter S, Salovey P, Cummings KM, Makuch RW, Toll BA. Nicotine dependence as a moderator of a quitline-based message framing intervention. Drug And Alcohol Dependence 2010, 114: 229-232. PMID: 21036492, PMCID: PMC3044773, DOI: 10.1016/j.drugalcdep.2010.09.012.
• Sample size for post‐marketing safety studies based on historical controlsWu Y, Makuch RW. Sample size for post‐marketing safety studies based on historical controls. Pharmacoepidemiology And Drug Safety 2010, 19: 869-875. PMID: 20572025, DOI: 10.1002/pds.1990.
• Low-dose naltrexone augmentation of nicotine replacement for smoking cessation with reduced weight gain: A randomized trialToll BA, White M, Wu R, Meandzija B, Jatlow P, Makuch R, O’Malley S. Low-dose naltrexone augmentation of nicotine replacement for smoking cessation with reduced weight gain: A randomized trial. Drug And Alcohol Dependence 2010, 111: 200-206. PMID: 20542391, PMCID: PMC3771701, DOI: 10.1016/j.drugalcdep.2010.04.015.
• S1918 A Hemodynamic Response to Treatment With Non-Selective Beta-Blockers Protects Against Worsening of Thrombocytopenia in CirrhosisQamar A, Grace N, Groszmann R, Garcia-Tsao G, Bosch J, Burroughs A, Iskandar H, Maurer R, Planas R, Escorsell A, Garcia-Pagan J, Patch D, Matloff D, Makuch R, From P. S1918 A Hemodynamic Response to Treatment With Non-Selective Beta-Blockers Protects Against Worsening of Thrombocytopenia in Cirrhosis. Gastroenterology 2010, 138: s-817. DOI: 10.1016/s0016-5085(10)63764-x.
• Functional connectivity to a right hemisphere language center in prematurely born adolescentsMyers EH, Hampson M, Vohr B, Lacadie C, Frost SJ, Pugh KR, Katz KH, Schneider KC, Makuch RW, Constable RT, Ment LR. Functional connectivity to a right hemisphere language center in prematurely born adolescents. NeuroImage 2010, 51: 1445-1452. PMID: 20347043, PMCID: PMC2872040, DOI: 10.1016/j.neuroimage.2010.03.049.
• GABAA‐benzodiazepine receptor availability in smokers and nonsmokers: Relationship to subsyndromal anxiety and depressionEsterlis I, Cosgrove KP, Batis JC, Bois F, Kloczynski TA, Stiklus SM, Perry E, Tamagnan GD, Seibyl JP, Makuch R, Krishnan‐Sarin S, O'Malley S, Staley JK. GABAA‐benzodiazepine receptor availability in smokers and nonsmokers: Relationship to subsyndromal anxiety and depression. Synapse 2009, 63: 1089-1099. PMID: 19642218, PMCID: PMC2778224, DOI: 10.1002/syn.20688.
• Alterations in neural connectivity in preterm children at school ageGozzo Y, Vohr B, Lacadie C, Hampson M, Katz KH, Maller-Kesselman J, Schneider KC, Peterson BS, Rajeevan N, Makuch RW, Constable RT, Ment LR. Alterations in neural connectivity in preterm children at school age. NeuroImage 2009, 48: 458-463. PMID: 19560547, PMCID: PMC2775072, DOI: 10.1016/j.neuroimage.2009.06.046.
• Incidence, Prevalence, and Clinical Significance of Abnormal Hematologic Indices in Compensated CirrhosisQamar AA, Grace ND, Groszmann RJ, Garcia–Tsao G, Bosch J, Burroughs AK, Ripoll C, Maurer R, Planas R, Escorsell A, Garcia–Pagan J, Patch D, Matloff DS, Makuch R, Rendon G, Group P. Incidence, Prevalence, and Clinical Significance of Abnormal Hematologic Indices in Compensated Cirrhosis. Clinical Gastroenterology And Hepatology 2009, 7: 689-695. PMID: 19281860, PMCID: PMC4545534, DOI: 10.1016/j.cgh.2009.02.021.
• Detecting Rare Adverse Events in Postmarketing Studies: Sample Size ConsiderationsWu Y, Makuch R. Detecting Rare Adverse Events in Postmarketing Studies: Sample Size Considerations. Therapeutic Innovation & Regulatory Science 2006, 40: 89-98. DOI: 10.1177/009286150604000111.
• Control Group Bias in Randomized Atypical Antipsychotic Medication Trials for SchizophreniaWoods SW, Gueorguieva RV, Baker CB, Makuch RW. Control Group Bias in Randomized Atypical Antipsychotic Medication Trials for Schizophrenia. JAMA Psychiatry 2005, 62: 961-970. PMID: 16143728, DOI: 10.1001/archpsyc.62.9.961.
• Cardiovascular thrombotic events in arthritis trials of the cyclooxygenase-2 inhibitor celecoxibWhite W, Faich G, Borer J, Makuch R. Cardiovascular thrombotic events in arthritis trials of the cyclooxygenase-2 inhibitor celecoxib. ACC Current Journal Review 2003, 12: 14-15. DOI: 10.1016/j.accreview.2003.09.051.
• Systematic review of NSAID-induced adverse reactions in patients with rheumatoid arthritis in JapanTomita T, Ochi T, Sugano K, Uemura S, Makuch R. Systematic review of NSAID-induced adverse reactions in patients with rheumatoid arthritis in Japan. Modern Rheumatology 2003, 13: 143-152. DOI: 10.1007/s10165-002-0214-5.
• 103 Multicenter randomized placebo-controlled trial of non-selective beta-blockers in the prevention of the complications of portal hypertension: final results and identification of a predictive factorGroszmann R, Garcia-Tsao G, Makuch R, Bosch J, Escorsel A, Garcia-Pagan J, Grace N, Matloff D, Burroughs A, Patch D. 103 Multicenter randomized placebo-controlled trial of non-selective beta-blockers in the prevention of the complications of portal hypertension: final results and identification of a predictive factor. Hepatology 2003, 38: 206. DOI: 10.1016/s0270-9139(03)80146-5.
• Which Factors Shape and Limit the Role of the Center for Drug Evaluation and Research's Advisory Committees?*Schulman S, Olson M, Makuch R. Which Factors Shape and Limit the Role of the Center for Drug Evaluation and Research's Advisory Committees?*. Therapeutic Innovation & Regulatory Science 2002, 36: 281-289. DOI: 10.1177/009286150203600206.
• Blood-pressure-lowering treatmentFaich G, Makuch R. Blood-pressure-lowering treatment. The Lancet 2001, 357: 718. PMID: 11247581, DOI: 10.1016/s0140-6736(05)71474-4.
• Heterogeneity Within the Gifted: Higher IQ Boys Exhibit Behaviors Resembling Boys With Learning DisabilitiesShaywitz S, Holahan J, Freudenheim D, Fletcher J, Makuch R, Shaywitz B. Heterogeneity Within the Gifted: Higher IQ Boys Exhibit Behaviors Resembling Boys With Learning Disabilities. Gifted Child Quarterly 2001, 45: 16-23. DOI: 10.1177/001698620104500103.
• Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm InfantsPeterson B, Vohr B, Staib L, Cannistraci C, Dolberg A, Schneider K, Katz K, Westerveld M, Sparrow S, Anderson A, Duncan C, Makuch R, Gore J, Ment L. Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants. JAMA 2000, 284: 1939-1947. PMID: 11035890, DOI: 10.1001/jama.284.15.1939.
• Gastrointestinal Toxicity With Celecoxib vs Nonsteroidal Anti-inflammatory Drugs for Osteoarthritis and Rheumatoid Arthritis: The CLASS Study: A Randomized Controlled TrialSilverstein F, Faich G, Goldstein J, Simon L, Pincus T, Whelton A, Makuch R, Eisen G, Agrawal N, Stenson W, Burr A, Zhao W, Kent J, Lefkowith J, Verburg K, Geis G. Gastrointestinal Toxicity With Celecoxib vs Nonsteroidal Anti-inflammatory Drugs for Osteoarthritis and Rheumatoid Arthritis: The CLASS Study: A Randomized Controlled Trial. JAMA 2000, 284: 1247-1255. PMID: 10979111, DOI: 10.1001/jama.284.10.1247.
• Upper gastrointestinal tolerability of celecoxib, a COX-2 specific inhibitor, compared to naproxen and placebo.Bensen W, Zhao S, Burke T, Zabinski R, Makuch R, Maurath C, Agrawal N, Geis G. Upper gastrointestinal tolerability of celecoxib, a COX-2 specific inhibitor, compared to naproxen and placebo. The Journal Of Rheumatology 2000, 27: 1876-83. PMID: 10955327.
• Guest Editor's NoteMakuch R. Guest Editor's Note. Therapeutic Innovation & Regulatory Science 2000, 34: 335-335. DOI: 10.1177/009286150003400201.
• Outcome of Children in the Indomethacin Intraventricular Hemorrhage Prevention TrialMent L, Vohr B, Allan W, Westerveld M, Sparrow S, Schneider K, Katz K, Duncan C, Makuch R. Outcome of Children in the Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 2000, 105: 485-491. PMID: 10699097, DOI: 10.1542/peds.105.3.485.
• The Stroke Prognosis Instrument II (SPI-II)Kernan W, Viscoli C, Brass L, Makuch R, Sarrel P, Roberts R, Gent M, Rothwell P, Sacco R, Liu R, Boden-Albala B, Horwitz R. The Stroke Prognosis Instrument II (SPI-II). Stroke 2000, 31: 456-462. PMID: 10657422, DOI: 10.1161/01.str.31.2.456.
• Blood Pressure Exceeding National Guidelines Among Women After StrokeKernan W, Viscoli C, Brass L, Makuch R, Sarrel P, Horwitz R. Blood Pressure Exceeding National Guidelines Among Women After Stroke. Stroke 2000, 31: 415-419. PMID: 10657415, DOI: 10.1161/01.str.31.2.415.
• Evaluation of Therapeutic Strategies: A New Method for Balancing Risk and BenefitTroche C, Paltiel A, Makuch R. Evaluation of Therapeutic Strategies: A New Method for Balancing Risk and Benefit. Value In Health 2000, 3: 12-22. PMID: 16464177, DOI: 10.1046/j.1524-4733.2000.31002.x.
• Use of Meta-Analysis to Evaluate Medical Questions of Interest: An Application to Studies of Secondary Prevention of Acute Myocardial InfarctionChen Y, Makuch R. Use of Meta-Analysis to Evaluate Medical Questions of Interest: An Application to Studies of Secondary Prevention of Acute Myocardial Infarction. Therapeutic Innovation & Regulatory Science 1999, 33: 1161-1171. DOI: 10.1177/009286159903300420.
• The Etiology and Outcome of Cerebral Ventriculomegaly at Term in Very Low Birth Weight Preterm InfantsMent L, Vohr B, Allan W, Westerveld M, Katz K, Schneider K, Makuch R. The Etiology and Outcome of Cerebral Ventriculomegaly at Term in Very Low Birth Weight Preterm Infants. Pediatrics 1999, 104: 243-248. PMID: 10429002, DOI: 10.1542/peds.104.2.243.
• Early-onset intraventricular hemorrhage in preterm neonates: Incidence of neurodevelopmental handicapVohr B, Allan W, Scott D, Katz K, Schneider K, Makuch R, Ment L. Early-onset intraventricular hemorrhage in preterm neonates: Incidence of neurodevelopmental handicap. Seminars In Perinatology 1999, 23: 212-217. PMID: 10405190, DOI: 10.1016/s0146-0005(99)80065-2.
• Stratified Randomization for Clinical TrialsKernan W, Viscoli C, Makuch R, Brass L, Horwitz R. Stratified Randomization for Clinical Trials. Journal Of Clinical Epidemiology 1999, 52: 19-26. PMID: 9973070, DOI: 10.1016/s0895-4356(98)00138-3.
• Association of chronic sublethal hypoxia with ventriculomegaly in the developing rat brainMent L, Schwartz M, Makuch R, Stewart W. Association of chronic sublethal hypoxia with ventriculomegaly in the developing rat brain. Brain Research 1998, 111: 197-203. PMID: 9838111, DOI: 10.1016/s0165-3806(98)00139-4.
• Portal hypertension and variceal bleeding: An AASLD single topic symposiumGrace N, Groszmann R, Garcia‐Tsao G, Burroughs A, Pagliaro L, Makuch R, Bosch J, Stiegmann G, Henderson J, de Franchis R, Wagner J, Conn H, Rodes J. Portal hypertension and variceal bleeding: An AASLD single topic symposium. Hepatology 1998, 28: 868-880. PMID: 9731585, DOI: 10.1002/hep.510280339.
• Verapamil use in patients with cardiovascular disease: An overview of randomized trialsPepine C, Faich G, Makuch R. Verapamil use in patients with cardiovascular disease: An overview of randomized trials. Clinical Cardiology 1998, 21: 633-641. PMID: 9755379, PMCID: PMC6655547, DOI: 10.1002/clc.4960210906.
• Prospective individual matching: covariate balance and power in a comparative studyMakuch R, Zhang Z, Charpentier P, Inouye S. Prospective individual matching: covariate balance and power in a comparative study. Statistics In Medicine 1998, 17: 1517-1526. PMID: 9695196, DOI: 10.1002/(sici)1097-0258(19980715)17:13<1517::aid-sim859>3.0.co;2-0.
• Cognitive Outcome at 4½ Years of Very Low Birth Weight Infants Enrolled in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention TrialMent L, Westerveld M, Makuch R, Vohr B, Allan W. Cognitive Outcome at 4½ Years of Very Low Birth Weight Infants Enrolled in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 1998, 102: 159-159. PMID: 9714645, DOI: 10.1542/peds.102.1.159.
• Clinical versus Statistical Considerations in the Design and Analysis of Clinical ResearchHorwitz R, Singer B, Makuch R, Viscoli C. Clinical versus Statistical Considerations in the Design and Analysis of Clinical Research. Journal Of Clinical Epidemiology 1998, 51: 305-307. PMID: 9539886, DOI: 10.1016/s0895-4356(98)00006-7.
• Estrogen after ischemic stroke: Clinical basis and design of The Women's Estrogen for Stroke TrialKernan W, Brass L, Viscoli C, Sarrel P, Makuch R, Horwitz R. Estrogen after ischemic stroke: Clinical basis and design of The Women's Estrogen for Stroke Trial. Journal Of Stroke And Cerebrovascular Diseases 1998, 7: 85-95. PMID: 17895061, DOI: 10.1016/s1052-3057(98)80026-8.
• Antecedents of Cerebral Palsy in a Multicenter Trial of Indomethacin for Intraventricular Hemorrhage-ReplyAllan W, Vohr B, Makuch R, Katz K, Ment L. Antecedents of Cerebral Palsy in a Multicenter Trial of Indomethacin for Intraventricular Hemorrhage-Reply. JAMA Pediatrics 1997, 151: 1270-1270. DOI: 10.1001/archpedi.1997.02170490095024.
• Antecedents of Cerebral Palsy in a Multicenter Trial of Indomethacin for Intraventricular HemorrhageAllan W, Vohr B, Makuch R, Katz K, Ment L. Antecedents of Cerebral Palsy in a Multicenter Trial of Indomethacin for Intraventricular Hemorrhage. JAMA Pediatrics 1997, 151: 580-585. PMID: 9193243, DOI: 10.1001/archpedi.1997.02170430046010.
• Outcome of the Very Low Birth Weight (VLBW) <1250G: Infants Residing in Bilingual and Non English Speaking Households Compared to Monolingual Households. † 1262Vohr B, Westerveld M, Leach T, Allen W, Katz K, Makuch R, Ment L. Outcome of the Very Low Birth Weight (VLBW) <1250G: Infants Residing in Bilingual and Non English Speaking Households Compared to Monolingual Households. † 1262. Pediatric Research 1997, 41: 213-213. DOI: 10.1203/00006450-199704001-01281.
• Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial.Ment L, Vohr B, Oh W, Scott D, Allan W, Westerveld M, Duncan C, Ehrenkranz R, Katz K, Schneider K, Makuch R. Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 1996, 98: 714-8. PMID: 8885951, DOI: 10.1542/peds.98.4.714.
• Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas.Piepmeier J, Susan Christopher R, Spencer D, Byrne T, Kim J, Knisel J, Lacy J, Tsukerman L, Makuch R. Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas. Neurosurgery 1996, 38: 872-8; discussion 878-9. PMID: 8727811, DOI: 10.1097/00006123-199605000-00002.
• Can treatment that is helpful on average be harmful to some patients? A study of the conflicting information needs of clinical inquiry and drug regulationHorwitz R, Singer B, Makuch R, Viscoli C. Can treatment that is helpful on average be harmful to some patients? A study of the conflicting information needs of clinical inquiry and drug regulation. Journal Of Clinical Epidemiology 1996, 49: 395-400. PMID: 8621989, DOI: 10.1016/0895-4356(95)00058-5.
• Psychiatric status after human fetal mesencephalic tissue transplantation in Parkinson's diseasePrice L, Spencer D, Marek K, Robbins R, Leranth C, Farhi A, Naftolin F, Roth R, Bunney B, Hoffer P, Makuch R, Redmond D. Psychiatric status after human fetal mesencephalic tissue transplantation in Parkinson's disease. Biological Psychiatry 1995, 38: 498-505. PMID: 8562661, DOI: 10.1016/0006-3223(95)00129-5.
• Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infantsMent L, Oh W, Ehrenkranz R, Philip A, Duncan C, Makuch R. Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants. American Journal Of Obstetrics And Gynecology 1995, 172: 795-800. PMID: 7892866, DOI: 10.1016/0002-9378(95)90001-2.
• Low-Dose Indomethacin and Prevention of Intraventricular HemorrhageMent L, Oh W, Ehrenkranz R, Philip A, Vohr B, Allan W, Dunean C, Scott D, Taylor K, Katz K, Schneider K, Makuch R. Low-Dose Indomethacin and Prevention of Intraventricular Hemorrhage. Obstetrical & Gynecological Survey 1994, 49: 613-614. DOI: 10.1097/00006254-199409000-00011.
• Low-dose indomethacin therapy and extension of intraventricular hemorrhage: A multicenter randomized trialMent L, Oh W, Ehrenkranz R, Phillip A, Vohr B, Allan W, Makuch R, Taylor K, Schneider K, Katz K, Scott D, Duncan C. Low-dose indomethacin therapy and extension of intraventricular hemorrhage: A multicenter randomized trial. The Journal Of Pediatrics 1994, 124: 951-955. PMID: 8201485, DOI: 10.1016/s0022-3476(05)83191-9.
• Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial.Ment L, Ehrenkranz R, Duncan C, Scott D, Taylor K, Katz K, Schneider K, Makuch R, Oh W, Vohr B, Philip A, Allan W. Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial. Pediatrics 1994, 93: 543-50. PMID: 8134206, DOI: 10.1542/peds.93.4.543.
• Low-Grade Astrocytomas May Arise from Different Astrocyte LineagesPiepmeier J, Fried I, Makuch R. Low-Grade Astrocytomas May Arise from Different Astrocyte Lineages. Neurosurgery 1993, 33: 627-632. DOI: 10.1097/00006123-199310000-00010.
• Low-grade astrocytomas may arise from different astrocyte lineages.Piepmeier J, Fried I, Makuch R. Low-grade astrocytomas may arise from different astrocyte lineages. Neurosurgery 1993, 33: 627-32. PMID: 8232801, DOI: 10.1227/00006123-199310000-00010.
• Risk period for intraventricular hemorrhage of the preterm neonate is independent of gestational age.Ment L, Oh W, Ehrenkranz R, Philip A, Schneider K, Katz K, Taylor K, Duncan C, Makuch R. Risk period for intraventricular hemorrhage of the preterm neonate is independent of gestational age. Seminars In Perinatology 1993, 17: 338-41. PMID: 8290976.
• Unilateral Transplantation of Human Fetal Mesencephalic Tissue Into the Caudate Nucleus of Patients With Parkinson's DiseaseSPENCER D, ROBBINS R, NAFTOLIN F, MAREK K, VOLLMER T, LERANTH C, ROTH R, PRICE L, GJEDDE A, BUNNEY B, SASS K, ELSWORTH J, KIER E, MAKUCH R, HOFFER P, REDMOND D. Unilateral Transplantation of Human Fetal Mesencephalic Tissue Into the Caudate Nucleus of Patients With Parkinson's Disease. Obstetrical & Gynecological Survey 1993, 48: 413-415. DOI: 10.1097/00006254-199306000-00013.
• A phase II trial of mitomycin C, 5-fluorouracil and radiation therapy in the treatment of unresectable non-small cell lung cancer.Murren J, Ganpule S, Papac R, Son Y, Peschel R, Durivage H, Buzaid A, Lamb L, Makuch R, Hait W. A phase II trial of mitomycin C, 5-fluorouracil and radiation therapy in the treatment of unresectable non-small cell lung cancer. Oncology Research Featuring Preclinical And Clinical Cancer Therapeutics 1993, 5: 53-7. PMID: 8395915.
• Unilateral Transplantation of Human Fetal Mesencephalic Tissue into the Caudate Nucleus of Patients with Parkinson's DiseaseSpencer D, Robbins R, Naftolin F, Marek K, Vollmer T, Leranth C, Roth R, Price L, Gjedde A, Bunney B, Sass K, Elsworth J, Kier E, Makuch R, Hoffer P, Redmond D. Unilateral Transplantation of Human Fetal Mesencephalic Tissue into the Caudate Nucleus of Patients with Parkinson's Disease. New England Journal Of Medicine 1992, 327: 1541-1548. PMID: 1435880, DOI: 10.1056/nejm199211263272201.
• Risk factors for early intraventricular hemorrhage in low birth weight infantsMent L, Oh W, Philip A, Ehrenkranz R, Duncan C, Allan W, Taylor K, Schneider K, Katz K, Makuch R. Risk factors for early intraventricular hemorrhage in low birth weight infants. The Journal Of Pediatrics 1992, 121: 776-783. PMID: 1432433, DOI: 10.1016/s0022-3476(05)81915-8.
• A model-based prediction for transvaginal ultrasonographic identification of early intrauterine pregnancyShapiro B, Escobar M, Makuch R, Lavy G, DeCherney A. A model-based prediction for transvaginal ultrasonographic identification of early intrauterine pregnancy. American Journal Of Obstetrics And Gynecology 1992, 166: 1495-1500. PMID: 1595805, DOI: 10.1016/0002-9378(92)91625-k.
• Evidence That Dyslexia May Represent the Lower Tail of a Normal Distribution of Reading AbilityShaywitz S, Escobar M, Shaywitz B, Fletcher J, Makuch R. Evidence That Dyslexia May Represent the Lower Tail of a Normal Distribution of Reading Ability. New England Journal Of Medicine 1992, 326: 145-150. PMID: 1727544, DOI: 10.1056/nejm199201163260301.
• A Phase II Trial of Cyclosporin A in the Treatment of Refractory Metastatic Colorectal CancerMurren J, Ganpule S, Sarris A, Durivage H, Davis C, Makuch R, Handschumacher R, Marsh J. A Phase II Trial of Cyclosporin A in the Treatment of Refractory Metastatic Colorectal Cancer. American Journal Of Clinical Oncology 1991, 14: 208-217. PMID: 2031507, DOI: 10.1097/00000421-199106000-00007.
• EEG coherence of prefrontal areas in normal and schizophrenic males during perceptual activationHoffman R, Buchsbaum M, Escobar M, Makuch R, Nuechterlein K, Guich S. EEG coherence of prefrontal areas in normal and schizophrenic males during perceptual activation. Journal Of Neuropsychiatry 1991, 3: 169-175. PMID: 1821231, DOI: 10.1176/jnp.3.2.169.
• High‐dose cisplatin plus dacarbazine in the treatment of metastatic melanomaMurren J, Derosa W, Durivage H, Davis C, Makuch R, Portlock C. High‐dose cisplatin plus dacarbazine in the treatment of metastatic melanoma. Cancer 1991, 67: 1514-1517. PMID: 2001539, DOI: 10.1002/1097-0142(19910315)67:6<1514::aid-cncr2820670609>3.0.co;2-q.
• myc family DNA amplification in 107 tumors and tumor cell lines from patients with small cell lung cancer treated with different combination chemotherapy regimens.Brennan J, O'Connor T, Makuch R, Simmons A, Russell E, Linnoila R, Phelps R, Gazdar A, Ihde D, Johnson B. myc family DNA amplification in 107 tumors and tumor cell lines from patients with small cell lung cancer treated with different combination chemotherapy regimens. Cancer Research 1991, 51: 1708-12. PMID: 1847842.
• A Two‐Sample Test for Incomplete Multivariate DataMakuch R, Escobar M, Merrill S. A Two‐Sample Test for Incomplete Multivariate Data. Journal Of The Royal Statistical Society Series C (Applied Statistics) 1991, 40: 202-212. DOI: 10.2307/2347934.
• Survival in children with perinatally acquired human immunodeficiency virus type 1 infectionScott G, Hutto C, Makuch R, Mastrucci M, O'Connor T, Mitchell C, Trapido E, Parks W. Survival in children with perinatally acquired human immunodeficiency virus type 1 infection. International Journal Of Gynecology & Obstetrics 1990, 33: 283-283. DOI: 10.1016/0020-7292(90)90032-g.
• Survival in children with perinatally acquired human immunodeficiency virus type 1 infectionScott G, Hutto C, Makuch R, Mastrucci M, O'Connor T, Mitchell C, Trapido E, Parks W. Survival in children with perinatally acquired human immunodeficiency virus type 1 infection. International Journal Of Gynecology & Obstetrics 1990, 33: 191-191. DOI: 10.1016/0020-7292(90)90639-3.
• A phase 1 study of ribavirin in human immunodeficiency virus-infected patients.Roberts R, Jurica K, Meyer W, Paxton H, Makuch R. A phase 1 study of ribavirin in human immunodeficiency virus-infected patients. The Journal Of Infectious Diseases 1990, 162: 638-42. PMID: 2117625, DOI: 10.1093/infdis/162.3.638.
• Survival in children with perinatally acquired human immunodeficiency virus type 1 infectionScott G, Hutto C, Makuch R, Mastrucci M, O'Connor T, Mitchell C, Trapido E, Parks W. Survival in children with perinatally acquired human immunodeficiency virus type 1 infection. International Journal Of Gynecology & Obstetrics 1990, 32: 389-390. DOI: 10.1016/0020-7292(90)90121-z.
• Ten-year survival of patients with small-cell lung cancer treated with combination chemotherapy with or without irradiation.Johnson B, Grayson J, Makuch R, Linnoila R, Anderson M, Cohen M, Glatstein E, Minna J, Ihde D. Ten-year survival of patients with small-cell lung cancer treated with combination chemotherapy with or without irradiation. Journal Of Clinical Oncology 1990, 8: 396-401. PMID: 2155310, DOI: 10.1200/jco.1990.8.3.396.
• A multicenter clinical trial of oral ribavirin in HIV-infected people with lymphadenopathyRoberts R, Hollinger F, Parks W, Rasheed S, Laurence J, Heseltine P, Makuch R, Lubina J, Johnson K, Group R. A multicenter clinical trial of oral ribavirin in HIV-infected people with lymphadenopathy. AIDS 1990, 4: 67-72. PMID: 1690551, DOI: 10.1097/00002030-199001000-00009.
• A multicenter clinical trial of oral ribavirin in HIV-infected patients with lymphadenopathy. The Ribavirin-LAS Collaborative Group.Roberts R, Dickinson G, Heseltine P, Leedom J, Mansell P, Rodriguez S, Johnson K, Lubina J, Makuch R. A multicenter clinical trial of oral ribavirin in HIV-infected patients with lymphadenopathy. The Ribavirin-LAS Collaborative Group. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1990, 3: 884-92. PMID: 1974628.
• Survival in Children with Perinatally Acquired Human Immunodeficiency Virus Type 1 InfectionScott G, Hutto C, Makuch R, Mastrucci M, O'Connor T, Mitchell C, Trapido E, Parks W. Survival in Children with Perinatally Acquired Human Immunodeficiency Virus Type 1 Infection. New England Journal Of Medicine 1989, 321: 1791-1796. PMID: 2594038, DOI: 10.1056/nejm198912283212604.
• Goodman and Kruskal's λ: A new look at an old measure of associationMakuch R, Rosenberg P, Scott G. Goodman and Kruskal's λ: A new look at an old measure of association. Statistics In Medicine 1989, 8: 619-631. PMID: 2727480, DOI: 10.1002/sim.4780080511.
• Issues in planning and interpreting active control equivalence studiesMakuch R, Johnson M. Issues in planning and interpreting active control equivalence studies. Journal Of Clinical Epidemiology 1989, 42: 503-511. PMID: 2661729, DOI: 10.1016/0895-4356(89)90146-7.
• Generalised Binomial Models to Examine the Historical Control Assumption in Active Control Equivalence StudiesMakuch R, Stephens M, Escobar M. Generalised Binomial Models to Examine the Historical Control Assumption in Active Control Equivalence Studies. Journal Of The Royal Statistical Society Series D (The Statistician) 1989, 38: 61-70. DOI: 10.2307/2349019.
• The design and implementation of a software system for clinical studies: An illustration based on the needs of a Comprehensive Cancer CenterVoynick I, Makuch R. The design and implementation of a software system for clinical studies: An illustration based on the needs of a Comprehensive Cancer Center. Journal Of Medical Systems 1988, 12: 295-304. PMID: 3230375, DOI: 10.1007/bf00996580.
• A prospective randomized trial of HLA‐matched versus mismatched single‐donor platelet transfusions in cancer patientsMesserschmidt G, Makuch R, Appelbaum F, Ungerleider R, Abrams R, O'Donnell J, Holohan T, Fontana J, Wright D, Anagnou N, Shan T, Chesbro B, Deisseroth A. A prospective randomized trial of HLA‐matched versus mismatched single‐donor platelet transfusions in cancer patients. Cancer 1988, 62: 795-801. PMID: 3293762, DOI: 10.1002/1097-0142(19880815)62:4<795::aid-cncr2820620426>3.0.co;2-7.
• Identifying prognostic factors in binary outcome data: An application using liver function tests and age to predict liver metastasesMakuch R, Rosenberg P, Mulshine J. Identifying prognostic factors in binary outcome data: An application using liver function tests and age to predict liver metastases. Statistics In Medicine 1988, 7: 843-856. PMID: 2842852, DOI: 10.1002/sim.4780070803.
• Statistical Methods for the Analysis of HIV-1 Core Polypeptide Antigen Data in Clinical StudiesMakuch R, Parks W. Statistical Methods for the Analysis of HIV-1 Core Polypeptide Antigen Data in Clinical Studies. AIDS Research And Human Retroviruses 1988, 4: 305-316. PMID: 3061416, DOI: 10.1089/aid.1988.4.305.
• myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course.Johnson B, Ihde D, Makuch R, Gazdar A, Carney D, Oie H, Russell E, Nau M, Minna J. myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course. Journal Of Clinical Investigation 1987, 79: 1629-1634. PMID: 3034978, PMCID: PMC424486, DOI: 10.1172/jci112999.
• Evaluation of circulating malignant cells provides prognostic information in cutaneous T cell lymphoma.Schechter G, Sausville E, Fischmann A, Soehnlen F, Eddy J, Matthews M, Gazdar A, Guccion J, Munson D, Makuch R. Evaluation of circulating malignant cells provides prognostic information in cutaneous T cell lymphoma. Blood 1987, 69: 841-9. PMID: 3493044, DOI: 10.1182/blood.v69.3.841.bloodjournal693841.
• Evaluation of circulating malignant cells provides prognostic information in cutaneous T cell lymphomaSchechter G, Schechter G, Sausville E, Sausville E, Fischmann A, Fischmann A, Soehnlen F, Soehnlen F, Eddy J, Eddy J, Matthews M, Matthews M, Gazdar A, Gazdar A, Guccion J, Guccion J, Munson D, Munson D, Makuch R, Makuch R, Bunn P. Evaluation of circulating malignant cells provides prognostic information in cutaneous T cell lymphoma. Blood 1987, 69: 841-849. DOI: 10.1182/blood.v69.3.841.841.
• Cytologic transformation in cutaneous T cell lymphoma: a clinicopathologic entity associated with poor prognosis.Dmitrovsky E, Matthews M, Bunn P, Schechter G, Makuch R, Winkler C, Eddy J, Sausville E, Ihde D. Cytologic transformation in cutaneous T cell lymphoma: a clinicopathologic entity associated with poor prognosis. Journal Of Clinical Oncology 1987, 5: 208-15. PMID: 3492594, DOI: 10.1200/jco.1987.5.2.208.
• Late intensive combined modality therapy followed by autologous bone marrow infusion in extensive-stage small-cell lung cancer.Ihde D, Deisseroth A, Lichter A, Bunn P, Carney D, Cohen M, Veach S, Makuch R, Johnston-Early A, Abrams R. Late intensive combined modality therapy followed by autologous bone marrow infusion in extensive-stage small-cell lung cancer. Journal Of Clinical Oncology 1986, 4: 1443-54. PMID: 3020181, DOI: 10.1200/jco.1986.4.10.1443.
• A trial of combination chemotherapy followed by hormonal therapy for previously untreated metastatic carcinoma of the prostate.Seifter E, Bunn P, Cohen M, Makuch R, Dunnick N, Javadpour N, Bensimon H, Eddy J, Minna J, Ihde D. A trial of combination chemotherapy followed by hormonal therapy for previously untreated metastatic carcinoma of the prostate. Journal Of Clinical Oncology 1986, 4: 1365-73. PMID: 2943877, DOI: 10.1200/jco.1986.4.9.1365.
• Changes in the phenotype of human small cell lung cancer cell lines after transfection and expression of the c-myc proto-oncogene.Johnson B, Battey J, Linnoila I, Becker K, Makuch R, Snider R, Carney D, Minna J. Changes in the phenotype of human small cell lung cancer cell lines after transfection and expression of the c-myc proto-oncogene. Journal Of Clinical Investigation 1986, 78: 525-532. PMID: 3016030, PMCID: PMC423589, DOI: 10.1172/jci112604.
• Serial determinations of glutathione levels and glutathione-related enzyme activities in human tumor cels in vitroBatist G, Behrens B, Makuch R, Hamilton T, Katki A, Louie K, Myers C, Ozols R. Serial determinations of glutathione levels and glutathione-related enzyme activities in human tumor cels in vitro. Biochemical Pharmacology 1986, 35: 2257-2259. PMID: 3827990, DOI: 10.1016/0006-2952(86)90601-5.
• Combined modality treatment of cutaneous T cell lymphoma: results of a 6-year follow-up.Winkler C, Sausville E, Ihde D, Fischmann A, Schechter G, Kumar P, Nibhanupdi J, Minna J, Makuch R, Eddy J. Combined modality treatment of cutaneous T cell lymphoma: results of a 6-year follow-up. Journal Of Clinical Oncology 1986, 4: 1094-100. PMID: 3088220, DOI: 10.1200/jco.1986.4.7.1094.
• Non-small-cell lung cancer. Major cause of late mortality in patients with small cell lung cancerJohnson B, Ihde D, Matthews M, Bunn P, Zabell A, Makuch R, Johnston-early A, Cohen M, Glatstein E, Minna J. Non-small-cell lung cancer. Major cause of late mortality in patients with small cell lung cancer. The American Journal Of Medicine 1986, 80: 1103-1110. PMID: 3014875, DOI: 10.1016/0002-9343(86)90672-8.
• Pulmonary toxicity with combined modality therapy for limited stage small-cell lung cancer.Brooks B, Seifter E, Walsh T, Lichter A, Bunn P, Zabell A, Johnston-Early A, Edison M, Makuch R, Cohen M. Pulmonary toxicity with combined modality therapy for limited stage small-cell lung cancer. Journal Of Clinical Oncology 1986, 4: 200-9. PMID: 3003259, DOI: 10.1200/jco.1986.4.2.200.
• Neurologic, neuropsychologic, and computed cranial tomography scan abnormalities in 2- to 10-year survivors of small-cell lung cancer.Johnson B, Becker B, Goff W, Petronas N, Krehbiel M, Makuch R, McKenna G, Glatstein E, Ihde D. Neurologic, neuropsychologic, and computed cranial tomography scan abnormalities in 2- to 10-year survivors of small-cell lung cancer. Journal Of Clinical Oncology 1985, 3: 1659-67. PMID: 2999346, DOI: 10.1200/jco.1985.3.12.1659.
• Histologic assessment of lymph nodes in mycosis fungoides/sézary syndrome (cutaneous T-cell lymphoma): Clinical correlations and prognostic import of a new classification systemSausville E, Worsham G, Matthews M, Makuch R, Fischmann A, Schechter G, Gazdar A, Bunn P. Histologic assessment of lymph nodes in mycosis fungoides/sézary syndrome (cutaneous T-cell lymphoma): Clinical correlations and prognostic import of a new classification system. Human Pathology 1985, 16: 1098-1109. PMID: 3876976, DOI: 10.1016/s0046-8177(85)80177-5.
• Patients with small-cell lung cancer treated with combination chemotherapy with or without irradiation. Data on potential cures, chronic toxicities, and late relapses after a five- to eleven-year follow-up.Johnson B, Ihde D, Bunn P, Becker B, Walsh T, Weinstein Z, Matthews M, Whang-Peng J, Makuch R, Johnston-Early A. Patients with small-cell lung cancer treated with combination chemotherapy with or without irradiation. Data on potential cures, chronic toxicities, and late relapses after a five- to eleven-year follow-up. Annals Of Internal Medicine 1985, 103: 430-8. PMID: 2992337, DOI: 10.7326/0003-4819-103-3-430.
• Effects of fractionated irradiation of endocrine aspects of testicular function.Shapiro E, Kinsella T, Makuch R, Fraass B, Glatstein E, Rosenberg S, Sherins R. Effects of fractionated irradiation of endocrine aspects of testicular function. Journal Of Clinical Oncology 1985, 3: 1232-9. PMID: 3928830, DOI: 10.1200/jco.1985.3.9.1232.
• The role of radiation therapy in the treatment of small cell lung cancerLichter A, Bunn P, Ihde D, Cohen M, Makuch R, Carney D, Johnston‐Early A, Minna J, Glatstein E. The role of radiation therapy in the treatment of small cell lung cancer. Cancer 1985, 55: 2163-2175. PMID: 2983875, DOI: 10.1002/1097-0142(19850501)55:9+<2163::aid-cncr2820551420>3.0.co;2-y.
• A COMPARISON OF COMPUTED TOMOGRAPHY AND RADIONUCLIDE SCANNING FOR DETECTION OF BRAIN METASTASES IN SMALL CELL LUNG CANCERCrane J, Nelson M, Ihde D, Makuch R, Glatstein E, Zabell A, Johnston-Early A, Bates H, Saini N, Cohen M, Bunn P. A COMPARISON OF COMPUTED TOMOGRAPHY AND RADIONUCLIDE SCANNING FOR DETECTION OF BRAIN METASTASES IN SMALL CELL LUNG CANCER. Journal Of Computer Assisted Tomography 1985, 9: 643. DOI: 10.1097/00004728-198505000-00085.
• Approaches to sample size estimation in the design of clinical trials—a reviewDonner B, Makuch R. Approaches to sample size estimation in the design of clinical trials—a review. Statistics In Medicine 1985, 4: 247-247. PMID: 4023483, DOI: 10.1002/sim.4780040215.
• Actuarial risk of isolated cns involvement in Ewing's sarcoma following prophylactic cranial irradiation and intrathecal methotrexateTrigg M, Makuch R, Glaubiger D. Actuarial risk of isolated cns involvement in Ewing's sarcoma following prophylactic cranial irradiation and intrathecal methotrexate. International Journal Of Radiation Oncology • Biology • Physics 1985, 11: 699-702. PMID: 3838542, DOI: 10.1016/0360-3016(85)90300-1.
• Prognostic factors in patients with hepatocellular carcinoma receiving systemic chemotherapy. Identification of two groups of patients with prospects for prolonged survivalIhde D, Matthews M, Makuch R, McIntire K, Eddy J, Seeff L. Prognostic factors in patients with hepatocellular carcinoma receiving systemic chemotherapy. Identification of two groups of patients with prospects for prolonged survival. The American Journal Of Medicine 1985, 78: 399-406. PMID: 2579551, DOI: 10.1016/0002-9343(85)90330-4.
• Predictive factors for tumor response to preoperative chemotherapy in patients with head and neck squamous carcinoma: The head and neck contracts programWolf G, Makuch R, Baker S. Predictive factors for tumor response to preoperative chemotherapy in patients with head and neck squamous carcinoma: The head and neck contracts program. Cancer 1984, 54: 2869-2877. PMID: 6208993, DOI: 10.1002/1097-0142(19841215)54:12<2869::aid-cncr2820541210>3.0.co;2-n.
• Elevated serum creatine kinase BB levels in patients with small cell lung cancer.Carney D, Zweig M, Ihde D, Cohen M, Makuch R, Gazdar A. Elevated serum creatine kinase BB levels in patients with small cell lung cancer. Cancer Research 1984, 44: 5399-403. PMID: 6091876.
• A comparison of computed tomography and radionuclide scanning for detection of brain metastases in small cell lung cancer.Crane J, Nelson M, Ihde D, Makuch R, Glatstein E, Zabell A, Johnston-Early A, Bates H, Saini N, Cohen M. A comparison of computed tomography and radionuclide scanning for detection of brain metastases in small cell lung cancer. Journal Of Clinical Oncology 1984, 2: 1017-24. PMID: 6088707, DOI: 10.1200/jco.1984.2.9.1017.
• Diagnosis and significance of liver metastases in small cell carcinoma of the lung.Mulshine J, Makuch R, Johnston-Early A, Matthews M, Carney D, Ihde D, Cohen M, Bates H, Dunnick N, Minna J. Diagnosis and significance of liver metastases in small cell carcinoma of the lung. Journal Of Clinical Oncology 1984, 2: 733-41. PMID: 6330314, DOI: 10.1200/jco.1984.2.7.733.
• Second malignant neoplasms complicating Hodgkin's disease: the National Cancer Institute experience.Tester W, Kinsella T, Waller B, Makuch R, Kelley P, Glatstein E, DeVita V. Second malignant neoplasms complicating Hodgkin's disease: the National Cancer Institute experience. Journal Of Clinical Oncology 1984, 2: 762-9. PMID: 6547479, DOI: 10.1200/jco.1984.2.7.762.
• A non‐parametric graphical representation of the relationship between survival and the occurrence of an event: Application to responder versus non‐responder biasSimon R, Makuch R. A non‐parametric graphical representation of the relationship between survival and the occurrence of an event: Application to responder versus non‐responder bias. Statistics In Medicine 1984, 3: 35-44. PMID: 6729287, DOI: 10.1002/sim.4780030106.
• Treatment of extensive stage small cell bronchogenic carcinoma Effects of variation in intensity of induction chemotherapyBrower M, Ihde D, Johnston-Early A, Bunn P, Cohen M, Carney D, Makuch R, Matthews M, Radice P, Minna J. Treatment of extensive stage small cell bronchogenic carcinoma Effects of variation in intensity of induction chemotherapy. The American Journal Of Medicine 1983, 75: 993-1000. PMID: 6316784, DOI: 10.1016/0002-9343(83)90880-x.
• Intensive combined modality therapy including low-dose TBI in high-risk ewing's sarcoma patientsKinsella T, Glaubiger D, Diesseroth A, Makuch R, Waller B, Pizzo P, Glatstein E. Intensive combined modality therapy including low-dose TBI in high-risk ewing's sarcoma patients. International Journal Of Radiation Oncology • Biology • Physics 1983, 9: 1955-1960. PMID: 9463099, DOI: 10.1016/0360-3016(83)90368-1.
• Delayed hypersensitivity skin testing as a prognostic indicator in patients with small cell lung cancerJohnston‐Early A, Cohen M, Fossieck B, Harwood S, Ihde D, Bunn P, Matthews M, Minna J, Makuch R. Delayed hypersensitivity skin testing as a prognostic indicator in patients with small cell lung cancer. Cancer 1983, 52: 1395-1400. PMID: 6311393, DOI: 10.1002/1097-0142(19831015)52:8<1395::aid-cncr2820520810>3.0.co;2-t.
• Role of prophylactic cranial irradiation in prevention of central nervous system metastases in small cell lung cancer Potential benefit restricted to patients with complete responseRosen S, Makuch R, Lichter A, Ihde D, Matthews M, Minna J, Glatstein E, Bunn P. Role of prophylactic cranial irradiation in prevention of central nervous system metastases in small cell lung cancer Potential benefit restricted to patients with complete response. The American Journal Of Medicine 1983, 74: 615-624. PMID: 6301274, DOI: 10.1016/0002-9343(83)91019-7.
• The clinical behavior of „mixed”︁ small cell/large cell bronchogenic carcinoma compared to „pure”︁ small cell subtypesRadice P, Matthews M, Ihde D, Gazdar A, Carney D, Bunn P, Cohen M, Fossieck B, Makuch R, Minna J. The clinical behavior of „mixed”︁ small cell/large cell bronchogenic carcinoma compared to „pure”︁ small cell subtypes. Cancer 1982, 50: 2894-2902. PMID: 6291745, DOI: 10.1002/1097-0142(19821215)50:12<2894::aid-cncr2820501232>3.0.co;2-g.
• Classification of cell lines derived from undifferentiated lymphomas according to their expression of complement and Epstein-Barr virus receptors: Implications for the relationship between African and American Burkitt's lymphomaFreeman C, Magrath I, Benjamin D, Makuch R, Douglass E, Santaella M. Classification of cell lines derived from undifferentiated lymphomas according to their expression of complement and Epstein-Barr virus receptors: Implications for the relationship between African and American Burkitt's lymphoma. Clinical Immunology 1982, 25: 103-113. PMID: 7151335, DOI: 10.1016/0090-1229(82)90169-6.
• Dose-response curves for predicting misonidazole-induced peripheral neuropathy.Schwade J, Makuch R, Strong J, Glatstein E. Dose-response curves for predicting misonidazole-induced peripheral neuropathy. Journal Of The National Cancer Institute 1982, 66: 1743-50. PMID: 6288238.
• Flow cytometric analysis of DNA content of bone marrow cells in patients with plasma cell myeloma: clinical implications.Bunn P, Krasnow S, Makuch R, Schlam M, Schechter G. Flow cytometric analysis of DNA content of bone marrow cells in patients with plasma cell myeloma: clinical implications. Blood 1982, 59: 528-35. PMID: 6800416, DOI: 10.1182/blood.v59.3.528.bloodjournal593528.
• Flow cytometric analysis of DNA content of bone marrow cells in patients with plasma cell myeloma: clinical implicationsBunn P, Bunn P, Krasnow S, Krasnow S, Makuch R, Makuch R, Schlam M, Schlam M, Schechter G, Schechter G. Flow cytometric analysis of DNA content of bone marrow cells in patients with plasma cell myeloma: clinical implications. Blood 1982, 59: 528-535. DOI: 10.1182/blood.v59.3.528.528.
• Sample size requirements for comparing time-to-failure among k treatment groupsMakuch R, Simon R. Sample size requirements for comparing time-to-failure among k treatment groups. Journal Of Clinical Epidemiology 1982, 35: 861-867. PMID: 7142364, DOI: 10.1016/0021-9681(82)90051-0.
• Carcinomatous Leptomeningitis in Small Cell Lung CancerROSEN S, AISNER J, MAKUCH R, MATTHEWS M, IHDE D, WHITACRE M, GLATSTEIN E, WIERNIK P, LICHTER A, BUNN P. Carcinomatous Leptomeningitis in Small Cell Lung Cancer. Medicine 1982, 61: 45. PMID: 6276648, DOI: 10.1097/00005792-198201000-00005.
• Der Wert der Laparoskopie in der Verlaufskontrolle des fortgeschrittenen OvarialkarzinomsOzols R, Fisher R, Anderson T, Makuch R, Young R. Der Wert der Laparoskopie in der Verlaufskontrolle des fortgeschrittenen Ovarialkarzinoms. Gynäkologische Rundschau 1982, 22: 132-133. DOI: 10.1159/000269288.
• Adjusted survival curve estimation using covariatesMakuch R. Adjusted survival curve estimation using covariates. Journal Of Clinical Epidemiology 1982, 35: 437-443. PMID: 7042727, DOI: 10.1016/0021-9681(82)90058-3.
• Experience of the National Cancer Institute (USA) in the treatment and biology of small cell lung cancer.Minna J, Bunn P, Carney D, Cohen M, Cuttita F, Fosieck B, Gazdar A, Ihde D, Johnston-Early A, Matthews M, Makuch R, Oie H, Rosen S, Lichter A, Glatstein E. Experience of the National Cancer Institute (USA) in the treatment and biology of small cell lung cancer. Bulletin Du Cancer 1982, 69: 83-93. PMID: 6280795.
• Adjuvant Immunotherapy or Chemotherapy for Malignant Melanoma: Preliminary Report of the National Cancer Institute Randomized Clinical TrialFisher R, Terry W, Hodes R, Rosenberg S, Makuch R, Gordon H, Fisher S. Adjuvant Immunotherapy or Chemotherapy for Malignant Melanoma: Preliminary Report of the National Cancer Institute Randomized Clinical Trial. Surgical Clinics Of North America 1981, 61: 1267-1277. PMID: 7031934, DOI: 10.1016/s0039-6109(16)42582-x.
• Preoperative Cisplatin and Bleomycin Therapy in Head and Neck Squamous Carcinoma: Prognostic Factors for Tumor ResponseBaker S, Makuch R, Wolf G. Preoperative Cisplatin and Bleomycin Therapy in Head and Neck Squamous Carcinoma: Prognostic Factors for Tumor Response. JAMA Otolaryngology - Head & Neck Surgery 1981, 107: 683-689. PMID: 6170283, DOI: 10.1001/archotol.1981.00790470031008.
• Growth of lung cancer colonies from bronchoscopy washingsVon Hoff D, Weisenthal L, Ihde D, Mathews M, Layard M, Makuch R. Growth of lung cancer colonies from bronchoscopy washings. Cancer 1981, 48: 400-403. PMID: 7016303, DOI: 10.1002/1097-0142(19810715)48:2<400::aid-cncr2820480229>3.0.co;2-j.
• Peritoneoscopy in the management of ovarian cancerOzols R, Fisher R, Anderson T, Makuch R, Young R. Peritoneoscopy in the management of ovarian cancer. American Journal Of Obstetrics And Gynecology 1981, 140: 611-619. PMID: 6455064, DOI: 10.1016/0002-9378(81)90192-7.
• Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapyVon Hoff D, Casper J, Bradley E, Sandbach J, Jones D, Makuch R. Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapy. The American Journal Of Medicine 1981, 70: 1027-1032. PMID: 7234870, DOI: 10.1016/0002-9343(81)90859-7.
• Prognostic Implications of Stage of Disease and Sites of Metastases in Patients with Small Cell Carcinoma of the Lung Treated with Intensive Combination Chemotherapy1,2Ihde D, Makuch R, Carney D, Bunn P, Cohen M, Matthews M, Minna J. Prognostic Implications of Stage of Disease and Sites of Metastases in Patients with Small Cell Carcinoma of the Lung Treated with Intensive Combination Chemotherapy1,2. American Journal Of Respiratory And Critical Care Medicine 1981, 123: 500-7. PMID: 6263137, DOI: 10.1164/arrd.1981.123.5.500.
• Influence of prognostic factors on survival in Ewing's sarcoma.Glaubiger D, Makuch R, Schwarz J. Influence of prognostic factors on survival in Ewing's sarcoma. National Cancer Institute Monograph 1981, 285-8. PMID: 7300894.
• Laboratory parameters as an alternative to performance status in prognostic stratification of patients with small cell lung cancer.Cohen M, Makuch R, Johnston-Early A, Ihde D, Bunn P, Fossieck B, Minna J. Laboratory parameters as an alternative to performance status in prognostic stratification of patients with small cell lung cancer. Journal Of The National Cancer Institute 1981, 65: 187-95. PMID: 6263468.
• Influence of histologic subtype of small cell carcinoma of the lung on clinical presentation, response to therapy, and survival.Carney D, Matthews M, Ihde D, Bunn P, Cohen M, Makuch R, Gazdar A, Minna J. Influence of histologic subtype of small cell carcinoma of the lung on clinical presentation, response to therapy, and survival. Journal Of The National Cancer Institute 1980, 65: 1225-30. PMID: 6253711, DOI: 10.1093/jnci/65.6.1225.
• Smoking Abstinence and Small Cell Lung Cancer Survival: An AssociationJohnston-Early A, Cohen M, Minna J, Paxton L, Fossieck B, Ihde D, Bunn P, Matthews M, Makuch R. Smoking Abstinence and Small Cell Lung Cancer Survival: An Association. JAMA 1980, 244: 2175-2179. DOI: 10.1001/jama.1980.03310190027016.
• Smoking abstinence and small cell lung cancer survival. An association.Johnston-Early A, Cohen M, Minna J, Paxton L, Fossieck B, Ihde D, Bunn P, Matthews M, Makuch R. Smoking abstinence and small cell lung cancer survival. An association. JAMA 1980, 244: 2175-9. PMID: 6252357, DOI: 10.1001/jama.244.19.2175.
• Direct cloning of human neuroblastoma cells in soft agar culture.Von Hoff D, Casper J, Bradley E, Trent J, Hodach A, Reichert C, Makuch R, Altman A. Direct cloning of human neuroblastoma cells in soft agar culture. Cancer Research 1980, 40: 3591-7. PMID: 7002289.
• Serum glycoproteins in cancer patients: First report of correlations with in vitro and in vivo parameters of cellular immunityBaskies A, Chretien P, Weiss J, Makuch R, Beveridge R, Catalona W, Spiegel H. Serum glycoproteins in cancer patients: First report of correlations with in vitro and in vivo parameters of cellular immunity. Cancer 1980, 45: 3050-3060. PMID: 7388749, DOI: 10.1002/1097-0142(19800615)45:12<3050::aid-cncr2820451229>3.0.co;2-8.
• Determination of prognostic factors and their influence on therapeutic results in patients with Ewing's sarcomaGlaubiger D, Makuch R, Schwarz J, Levine A, Johnson R. Determination of prognostic factors and their influence on therapeutic results in patients with Ewing's sarcoma. Cancer 1980, 45: 2213-2219. PMID: 7370962, DOI: 10.1002/1097-0142(19800415)45:8<2213::aid-cncr2820450834>3.0.co;2-l.
• Sample size considerations for non-randomized comparative studiesMakuch R, Simon R. Sample size considerations for non-randomized comparative studies. Journal Of Clinical Epidemiology 1980, 33: 175-181. PMID: 7354106, DOI: 10.1016/0021-9681(80)90017-x.
• EFFECTS OF THYMOSIN IN VITRO IN CANCER PATIENTS AND CORRELATION WITH CLINICAL COURSE AFTER THYMOSIN IMMUNOTHERAPYChretien P, Lipson S, Makuch R, Kenady D, Cohen M. EFFECTS OF THYMOSIN IN VITRO IN CANCER PATIENTS AND CORRELATION WITH CLINICAL COURSE AFTER THYMOSIN IMMUNOTHERAPY. Annals Of The New York Academy Of Sciences 1979, 332: 135-147. PMID: 316979, DOI: 10.1111/j.1749-6632.1979.tb47107.x.
• Serum glycoproteins and immunoglobulins in nasopharyngeal carcinoma Correlations with Epstein-Barr virus associated antibodies and clinical tumor stageBaskies A, Chretien P, Yang C, Wolf G, Makuch R, Tu S, Hsu M, Lynn T, Yang H, Weiss J, Spiegel H. Serum glycoproteins and immunoglobulins in nasopharyngeal carcinoma Correlations with Epstein-Barr virus associated antibodies and clinical tumor stage. The American Journal Of Surgery 1979, 138: 478-488. PMID: 225960, DOI: 10.1016/0002-9610(79)90406-9.
• Serum glycoproteins in head and neck squamous carcinoma Correlations with tumor extent, clinical tumor stage, and T-cell levels during chemotherapyWolf G, Chretien P, Elias E, Makuch R, Baskies A, Spiegel H, Weiss J. Serum glycoproteins in head and neck squamous carcinoma Correlations with tumor extent, clinical tumor stage, and T-cell levels during chemotherapy. The American Journal Of Surgery 1979, 138: 489-500. PMID: 90464, DOI: 10.1016/0002-9610(79)90407-0.
• Recommendations for the analysis of the effect of treatment on the development of second malignanciesMakuch R, Simon R. Recommendations for the analysis of the effect of treatment on the development of second malignancies. Cancer 1979, 44: 250-253. PMID: 455251, DOI: 10.1002/1097-0142(197907)44:1<250::aid-cncr2820440141>3.0.co;2-1.
• Thymosin Fraction V and Intensive Combination Chemotherapy: Prolonging the Survival of Patients With Small-Cell Lung CancerCohen M, Chretien P, Ihde D, Fossieck B, Makuch R, Bunn P, Johnston A, Shackney S, Matthews M, Lipson S, Kenady D, Minna J. Thymosin Fraction V and Intensive Combination Chemotherapy: Prolonging the Survival of Patients With Small-Cell Lung Cancer. JAMA 1979, 241: 1813-1815. DOI: 10.1001/jama.1979.03290430031019.
• Thymosin fraction V and intensive combination chemotherapy. Prolonging the survival of patients with small-cell lung cancer.Cohen M, Chretien P, Ihde D, Fossieck B, Makuch R, Bunn P, Johnston A, Shackney S, Matthews M, Lipson S, Kenady D, Minna J. Thymosin fraction V and intensive combination chemotherapy. Prolonging the survival of patients with small-cell lung cancer. JAMA 1979, 241: 1813-5. PMID: 219267, DOI: 10.1001/jama.241.17.1813.
• Improvements in circulating levels of immune-reactive proteins simultaneous with depression of thymus-dependent lymphocytes during radiation therapy for solid malignanciesBaskies A, Chretien P, Weiss J, Makuch R, Spiegel H. Improvements in circulating levels of immune-reactive proteins simultaneous with depression of thymus-dependent lymphocytes during radiation therapy for solid malignancies. International Journal Of Radiation Oncology • Biology • Physics 1979, 5: 67-68. DOI: 10.1016/0360-3016(79)91047-2.
• Thymosin immunotherapy in patients with small cell carcinoma of the lung. Correlation of in vitro studies with clinical courseLipson S, Chretien P, Makuch R, Kenady D, Cohen M. Thymosin immunotherapy in patients with small cell carcinoma of the lung. Correlation of in vitro studies with clinical course. Cancer 1979, 43: 863-870. PMID: 218717, DOI: 10.1002/1097-0142(197903)43:3<863::aid-cncr2820430313>3.0.co;2-5.
• Cyclic alternating combination chemotherapy for small cell bronchogenic carcinoma.Cohen M, Ihde D, Bunn P, Fossieck B, Matthews M, Shackney S, Johnston-Early A, Makuch R, Minna J. Cyclic alternating combination chemotherapy for small cell bronchogenic carcinoma. Journal Of The National Cancer Institute 1979, 63: 163-70. PMID: 221114.
• Effects of Thymosin Fraction 5 in Cancer Patients: In Vitro Studies and Correlations with Clinical Course in Patients Receiving ThymosinChretien P, Lipson S, Makuch R, Kenady D, Snyder J, Cohen M. Effects of Thymosin Fraction 5 in Cancer Patients: In Vitro Studies and Correlations with Clinical Course in Patients Receiving Thymosin. 1979, 159-166. DOI: 10.1016/b978-0-08-023194-5.50023-1.
• Abnormalities of Zinc and Copper During Total Parenteral NutritionLOWRY S, GOODGAME J, SMITH J, MAHER M, MAKUCH R, HENKIN R, BRENNAN M. Abnormalities of Zinc and Copper During Total Parenteral Nutrition. Annals Of Surgery 1979, 189: 120. PMID: 103506, PMCID: PMC1396940, DOI: 10.1097/00000658-197901000-00023.
• Justification for the lognormal distribution as a model for blood pressureMakuch R, Freeman D, Johnson M. Justification for the lognormal distribution as a model for blood pressure. Journal Of Clinical Epidemiology 1979, 32: 245-250. PMID: 429469, DOI: 10.1016/0021-9681(79)90070-5.
• cis-Dichlorodiammineplatinum(II) for the treatment of advanced ovarian cancer.Young R, Von Hoff D, Gormley P, Makuch R, Cassidy J, Howser D, Bull J. cis-Dichlorodiammineplatinum(II) for the treatment of advanced ovarian cancer. Journal Of The National Cancer Institute 1979, 63: 1539-44. PMID: 387224.
• Thymosin in cancer patients: in vitro effects and correlations with clinical response to thymosin immunotherapy.Chretien P, Lipson S, Makuch R, Kenady D, Cohen M, Minna J. Thymosin in cancer patients: in vitro effects and correlations with clinical response to thymosin immunotherapy. Journal Of The National Cancer Institute 1978, 62: 1787-90. PMID: 215307.
• Granulocyte transfusion therapy of experimental Pseudomonas septicemia: study of cell dose and collection technique.Appelbaum F, Bowles C, Makuch R, Deisseroth A. Granulocyte transfusion therapy of experimental Pseudomonas septicemia: study of cell dose and collection technique. Blood 1978, 52: 323-31. PMID: 667359, DOI: 10.1182/blood.v52.2.323.bloodjournal522323.
• Granulocyte transfusion therapy of experimental Pseudomonas septicemia: study of cell dose and collection techniqueAppelbaum F, Bowles C, Makuch R, Deisseroth A. Granulocyte transfusion therapy of experimental Pseudomonas septicemia: study of cell dose and collection technique. Blood 1978, 52: 323-331. DOI: 10.1182/blood.v52.2.323.323.
• CEA levels as an index of prognosis in patients receiving radiotherapy for carcinoma of the lungLipson S, Kenady D, Makuch R, Chretion P. CEA levels as an index of prognosis in patients receiving radiotherapy for carcinoma of the lung. International Journal Of Radiation Oncology • Biology • Physics 1978, 4: 71-72. DOI: 10.1016/0360-3016(78)90667-3.
• 2000 EFFECTS OF THYMOSIN IN CANCER PATIENTS: IN VITRO AND IN VIVO STUDIESChretien P, Lipson S, Cohen M, Makuch R. 2000 EFFECTS OF THYMOSIN IN CANCER PATIENTS: IN VITRO AND IN VIVO STUDIES. 1978, 623. DOI: 10.1016/b978-0-08-023768-8.51611-x.
• Chen, Y.T. and Makuch, R.W.: Use of Meta-Analysis to Evaluate Medical Questions of Interest: An Application to Studies of Secondary Prevention of Acute Myocardial Infarction. Drug Information Journal, 33:1161-1171, 1999.Chen, Y.T. and Makuch, R.W.: Use of Meta-Analysis to Evaluate Medical Questions of Interest: An Application to Studies of Secondary Prevention of Acute Myocardial Infarction. Drug Information Journal, 33:1161-1171, 1999.
• Wu, Y-Te. and Makuch, R.W. Detecting rare adverse events in post-marketing studies: sample size considerations. Drug Information Journal 40: 87-96, 2006.Wu, Y-Te. and Makuch, R.W. Detecting rare adverse events in post-marketing studies: sample size considerations. Drug Information Journal 40: 87-96, 2006.