Paul Clark, PhD
Associate Research Scientist in Genetics
Research & Publications
Biography
Coauthors
Selected Publications
- The Receptor for Advanced Glycation Endproducts Drives T Cell Survival and Inflammation in Type 1 Diabetes MellitusDurning SP, Preston-Hurlburt P, Clark PR, Xu D, Herold KC, Group T. The Receptor for Advanced Glycation Endproducts Drives T Cell Survival and Inflammation in Type 1 Diabetes Mellitus. The Journal Of Immunology 2016, 197: 3076-3085. PMID: 27655844, PMCID: PMC5101164, DOI: 10.4049/jimmunol.1600197.
- Tumor Necrosis Factor Disrupts Claudin-5 Endothelial Tight Junction Barriers in Two Distinct NF-κB-Dependent PhasesClark PR, Kim RK, Pober JS, Kluger MS. Tumor Necrosis Factor Disrupts Claudin-5 Endothelial Tight Junction Barriers in Two Distinct NF-κB-Dependent Phases. PLOS ONE 2015, 10: e0120075. PMID: 25816133, PMCID: PMC4376850, DOI: 10.1371/journal.pone.0120075.
- MEK5 is Activated by Shear Stress, Activates ERK5 and Induces KLF4 to Modulate TNF Responses in Human Dermal Microvascular Endothelial CellsCLARK PR, JENSEN TJ, KLUGER MS, MORELOCK M, HANIDU A, QI Z, TATAKE RJ, POBER JS. MEK5 is Activated by Shear Stress, Activates ERK5 and Induces KLF4 to Modulate TNF Responses in Human Dermal Microvascular Endothelial Cells. Microcirculation 2011, 18: 102-117. PMID: 21166929, PMCID: PMC3075844, DOI: 10.1111/j.1549-8719.2010.00071.x.
- Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effectClark PR, Pober JS, Kluger MS. Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect. Nucleic Acids Research 2007, 36: 1081-1097. PMID: 18096615, PMCID: PMC2275081, DOI: 10.1093/nar/gkm630.
- Increased ICAM-1 Expression Causes Endothelial Cell Leakiness, Cytoskeletal Reorganization and Junctional AlterationsClark PR, Manes TD, Pober JS, Kluger MS. Increased ICAM-1 Expression Causes Endothelial Cell Leakiness, Cytoskeletal Reorganization and Junctional Alterations. Journal Of Investigative Dermatology 2006, 127: 762-774. PMID: 17195014, DOI: 10.1038/sj.jid.5700670.
- The inducible Hsp70 as a marker of tumor immunogenicity.Clark PR, Ménoret A. The inducible Hsp70 as a marker of tumor immunogenicity. Cell Stress & Chaperones 2001, 6: 121-5. PMID: 11599573, PMCID: PMC434389.
- A novel drug screening assay for papillomavirus specific antiviral activity.Clark PR, Roberts ML, Cowsert LM. A novel drug screening assay for papillomavirus specific antiviral activity. Antiviral Research 1998, 37: 97-106. PMID: 9588842.