Oliver Karam, MD, PhD
Research & Publications
Biography
News
Research Summary
Dr. Karam focuses his research on transfusion strategies in critically ill children, assessment of bleeding, and anticoagulation on extracorporeal life support.
Extensive Research Description
Bleeding: Bleeding is a frequent complication of critical illness that is associated with significant mortality and morbidity. However, very little is known about bleeding in critically ill children. Dr. Karam's main research focus pertains to the epidemiology of bleeding in critically ill children. In a systematic review, he has shown that, although there are numerous definitions related to bleeding's clinical significance, none are designed for critically ill children. He then used an internationally distributed survey to explore the perceived severity of bleeding in critically ill children. He showed that characteristics most frequently identified as clinically relevant were bleeding in critical locations (e.g., pericardium, pleural space, CNS, and lungs); requiring interventions; leading to physiologic repercussions, including organ failure; and prolonged duration. He then designed an international consensus definition; with the help of 31 experts, he defined bleeding in critically ill children, which was the first definition to be validated in this specific population. He then further explored the relationship between bleeding and poor outcome, examining chest tube bleeding in children on ECMO. He showed a dose-response relationship between bleeding and mortality. These studies have allowed him to develop a new, operationalizable, bleeding definition that is now used in clinical studies. He has set the foundation for future studies, by establishing a consensus definition that is applicable to this patient population.
Thrombosis: The other side of Dr. Karam's research on bleeding is on thrombotic complications, as most therapies that aim to decrease bleeding put patients at increased thrombotic risk. He has evaluated antithrombin's effect on thrombotic complications after pediatric liver transfusion. He has also designed an international survey that identified the heterogeneity of antithrombotic strategies in various transplantation teams around the world. Finally, he evaluated the effect of transfusions on thrombotic complications in an extensive dataset of more than 400,000 children. He showed that perioperative red blood cell transfusions were independently associated with postoperative thrombotic events in children.
Extracorporeal life support: Dr. Karam has two leading research focuses within extracorporeal life support. First, as the extracorporeal circuit is very pro-thrombotic, virtually all patients require anticoagulation, which puts patients at risk of bleeding. In a systematic review and meta-analysis, he has identified the optimal test to guide anticoagulation. His next step is a randomized controlled trial that will evaluate two platelet transfusion thresholds in children on extracorporeal life support. Second, although thousands of children are placed on ECMO during active cardiopulmonary resuscitation, the indications remain unclear. He has designed a score that should help identify ECMO's appropriate indications when the benefits outweigh the risks.
Coauthors
Research Interests
Blood Coagulation; Blood Platelets; Blood Transfusion; Hemorrhage; Hemostasis; Regression Analysis; Extracorporeal Membrane Oxygenation; Randomized Controlled Trial; Sepsis
Selected Publications
- First nosocomial infections in children supported by veno-arterial extracorporeal membrane oxygenation (VA-ECMO)Cousin V, Rodriguez-Vigouroux R, Karam O, Rimensberger P, Posfay-Barbe K. First nosocomial infections in children supported by veno-arterial extracorporeal membrane oxygenation (VA-ECMO) BMC Pediatrics 2023, 23: 89. PMID: 36823601, PMCID: PMC9948414, DOI: 10.1186/s12887-023-03908-3.
- Cardiac manifestations of multisystem inflammatory syndrome of children after SARS-CoV-2 infection: a systematic review and meta-analysis.Carmona C, Kuziez M, Freitas C, Cyrus J, Bain J, Karam O. Cardiac manifestations of multisystem inflammatory syndrome of children after SARS-CoV-2 infection: a systematic review and meta-analysis. Cardiology In The Young 2023, 1-9. PMID: 36762563, DOI: 10.1017/s104795112300015x.
- Epidemiology of anticoagulation for children supported by extracorporeal membrane oxygenation in the United States: A Pediatric Hospital Information System database study.Nellis M, An A, Mahmood H, Prishtina F, Hena Z, Karam O. Epidemiology of anticoagulation for children supported by extracorporeal membrane oxygenation in the United States: A Pediatric Hospital Information System database study. Perfusion 2023, 2676591221151027. PMID: 36606508, DOI: 10.1177/02676591221151027.
- Transfusion Strategies in the 21st Century A Case-Based Narrative ReportShenker J, Abuelhija H, Karam O, Nellis M. Transfusion Strategies in the 21st Century A Case-Based Narrative Report Critical Care Clinics 2022, 39: 287-298. PMID: 36898774, DOI: 10.1016/j.ccc.2022.09.005.
- Transfusion Strategies in the 21st Century A Case-Based Narrative ReportShenker J, Abuelhija H, Karam O, Nellis M. Transfusion Strategies in the 21st Century A Case-Based Narrative Report Critical Care Clinics 2022 DOI: 10.1016/j.ccc.2022.09.005.
- Prophylactic Use of Antifibrinolytics During Pediatric Cardiac Surgery With Cardiopulmonary Bypass on Postoperative Bleeding and Transfusion: A Systematic Review and Meta-Analysis.Schertz K, Karam O, Demetres M, Mayadunna S, Faraoni D, Nellis ME. Prophylactic Use of Antifibrinolytics During Pediatric Cardiac Surgery With Cardiopulmonary Bypass on Postoperative Bleeding and Transfusion: A Systematic Review and Meta-Analysis. Pediatric Critical Care Medicine 2022, 23: e517-e529. PMID: 35997516, DOI: 10.1097/pcc.0000000000003049.
- Editorial: Sedation and analgesia challenges in critically ill neonates and childrenAmigoni A, Simons S, De Hoog M, De Wildt SN, Karam O. Editorial: Sedation and analgesia challenges in critically ill neonates and children Frontiers In Pediatrics 2022, 10: 1003736. PMID: 36061397, PMCID: PMC9434329, DOI: 10.3389/fped.2022.1003736.
- Anticoagulation strategies and recurrence of venous thromboembolic events in patients with sickle cell disease: a systematic review and meta-analysisEl-Amin N, Iness A, Cyrus JW, Sisler I, Karam O. Anticoagulation strategies and recurrence of venous thromboembolic events in patients with sickle cell disease: a systematic review and meta-analysis Annals Of Hematology 2022, 101: 1931-1940. PMID: 35895101, DOI: 10.1007/s00277-022-04901-z.
- Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Severe Traumatic Brain InjuryDengler BA, Karam O, Barthol CA, Chance A, Snider LE, Mundy CM, Bounajem MT, Johnson WC, Maita MM, Mendez-Gomez PM, Seifi A, Hafeez S. Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Severe Traumatic Brain Injury Critical Care Research And Practice 2022, 2022: 3834165. PMID: 35637760, PMCID: PMC9148235, DOI: 10.1155/2022/3834165.
- Effect of Platelet Transfusions on Extracorporeal Life Support Oxygenator’s FunctionChegondi M, Vijayakumar N, Badheka A, Karam O. Effect of Platelet Transfusions on Extracorporeal Life Support Oxygenator’s Function Frontiers In Pediatrics 2022, 10: 826477. PMID: 35321010, PMCID: PMC8936087, DOI: 10.3389/fped.2022.826477.
- What Laboratory Tests and Physiologic Triggers Should Guide the Decision to Administer a Platelet or Plasma Transfusion in Critically Ill Children and What Product Attributes Are Optimal to Guide Specific Product Selection? From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding.Delaney M, Karam O, Lieberman L, Steffen K, Muszynski JA, Goel R, Bateman ST, Parker RI, Nellis ME, Remy KE. What Laboratory Tests and Physiologic Triggers Should Guide the Decision to Administer a Platelet or Plasma Transfusion in Critically Ill Children and What Product Attributes Are Optimal to Guide Specific Product Selection? From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding. Pediatric Critical Care Medicine 2022, 23: e1-e13. PMID: 34989701, PMCID: PMC8769352, DOI: 10.1097/pcc.0000000000002854.
- Plasma and Platelet Transfusion Strategies in Critically Ill Children With Malignancy, Acute Liver Failure and/or Liver Transplantation, or Sepsis: From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding.Lieberman L, Karam O, Stanworth SJ, Goobie SM, Crighton G, Goel R, Lacroix J, Nellis ME, Parker RI, Steffen K, Stricker P, Valentine SL, Steiner ME. Plasma and Platelet Transfusion Strategies in Critically Ill Children With Malignancy, Acute Liver Failure and/or Liver Transplantation, or Sepsis: From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding. Pediatric Critical Care Medicine 2022, 23: e37-e49. PMID: 34989704, PMCID: PMC8769367, DOI: 10.1097/pcc.0000000000002857.
- Executive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusion Practice in Critically Ill Children: From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding (TAXI-CAB).Nellis ME, Karam O, Valentine SL, Bateman ST, Remy KE, Lacroix J, Cholette JM, Bembea MM, Russell RT, Steiner ME, Goobie SM, Tucci M, Stricker PA, Stanworth SJ, Delaney M, Lieberman L, Muszynski JA, Bauer DF, Steffen K, Nishijima D, Ibla J, Emani S, Vogel AM, Haas T, Goel R, Crighton G, Delgado D, Demetres M, Parker RI. Executive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusion Practice in Critically Ill Children: From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding (TAXI-CAB). Pediatric Critical Care Medicine 2022, 23: 34-51. PMID: 34989711, PMCID: PMC8820267, DOI: 10.1097/pcc.0000000000002851.
- Coagulation Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.Faustino EVS, Karam O, Parker RI, Hanson SJ, Brandão LR, Monagle P. Coagulation Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics 2022, 149: s79-s83. PMID: 34970670, DOI: 10.1542/peds.2021-052888l.
- Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary.Bembea MM, Agus M, Akcan-Arikan A, Alexander P, Basu R, Bennett TD, Bohn D, Brandão LR, Brown AM, Carcillo JA, Checchia P, Cholette J, Cheifetz IM, Cornell T, Doctor A, Eckerle M, Erickson S, Farris RWD, Faustino EVS, Fitzgerald JC, Fuhrman DY, Giuliano JS, Guilliams K, Gaies M, Gorga SM, Hall M, Hanson SJ, Hartman M, Hassinger AB, Irving SY, Jeffries H, Jouvet P, Kannan S, Karam O, Khemani RG, Kissoon N, Lacroix J, Laussen P, Leclerc F, Lee JH, Leteurtre S, Lobner K, McKiernan PJ, Menon K, Monagle P, Muszynski JA, Odetola F, Parker R, Pathan N, Pierce RW, Pineda J, Prince JM, Robinson KA, Rowan CM, Ryerson LM, Sanchez-Pinto LN, Schlapbach LJ, Selewski DT, Shekerdemian LS, Simon D, Smith LS, Squires JE, Squires RH, Sutherland SM, Ouellette Y, Spaeder MC, Srinivasan V, Steiner ME, Tasker RC, Thiagarajan R, Thomas N, Tissieres P, Traube C, Tucci M, Typpo KV, Wainwright MS, Ward SL, Watson RS, Weiss S, Whitney J, Willson D, Wynn JL, Yehya N, Zimmerman JJ. Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Pediatrics 2022, 149: s1-s12. PMID: 34970673, PMCID: PMC9599725, DOI: 10.1542/peds.2021-052888b.
- Accuracy of Bioimpedance Modalities for Fluid Assessment in Hemodialysis Patients: A Randomized Observational StudyJohn J, Division of Pediatric Nephrology C, Gipson G, King C, Bunchman T, Karam O, Division of Nephrology V, Division of Pediatric Critical Care Medicine C. Accuracy of Bioimpedance Modalities for Fluid Assessment in Hemodialysis Patients: A Randomized Observational Study Nephrology - Open Journal 2021, 6: 1-7. DOI: 10.17140/npoj-6-124.
- 660: FACTORS ASSOCIATED WITH RECURRENT THROMBOSIS IN PEDIATRIC PATIENTS RECEIVING ECMO THERAPYHughes T, Treffalls R, Dalton H, Karam O, Meyer A. 660: FACTORS ASSOCIATED WITH RECURRENT THROMBOSIS IN PEDIATRIC PATIENTS RECEIVING ECMO THERAPY Critical Care Medicine 2021, 50: 323-323. DOI: 10.1097/01.ccm.0000808964.56608.d9.
- 866: THE EFFECTS OF EXPECTATION SETTING AND BUNDLE CONSENT ON CAREGIVER STRESS IN THE PEDIATRIC ICUGoldstein G, Karam O, Ferguson N. 866: THE EFFECTS OF EXPECTATION SETTING AND BUNDLE CONSENT ON CAREGIVER STRESS IN THE PEDIATRIC ICU Critical Care Medicine 2021, 50: 428-428. DOI: 10.1097/01.ccm.0000809788.66396.1a.
- 1270: STUCK IN THE DARK: NO ASSOCIATION BETWEEN LIGHT, SOUND, AND DELIRIUM IN THE PICUKaram O, Greenfield K, O’Meara A. 1270: STUCK IN THE DARK: NO ASSOCIATION BETWEEN LIGHT, SOUND, AND DELIRIUM IN THE PICU Critical Care Medicine 2021, 50: 635-635. DOI: 10.1097/01.ccm.0000811404.65256.c2.
- 502: PROSPECTIVE VALIDATION OF BASIC DEFINITION OF BLEEDING IN DIVERSE COHORT OF CRITICALLY ILL CHILDRENNellis M, Willems A, Alqahtani M, Gerlak E, Karam O. 502: PROSPECTIVE VALIDATION OF BASIC DEFINITION OF BLEEDING IN DIVERSE COHORT OF CRITICALLY ILL CHILDREN Critical Care Medicine 2021, 50: 242-242. DOI: 10.1097/01.ccm.0000808332.61092.aa.
- Airway microbiome dynamics and relationship to ventilator‐associated infection in intubated pediatric patientsTarquinio KM, Karsies T, Shein SL, Beardsley A, Khemani R, Schwarz A, Smith L, Flori H, Karam O, Cao Q, Haider Z, Smirnova E, Serrano MG, Buck GA, Willson DF. Airway microbiome dynamics and relationship to ventilator‐associated infection in intubated pediatric patients Pediatric Pulmonology 2021, 57: 508-518. PMID: 34811963, PMCID: PMC8809006, DOI: 10.1002/ppul.25769.
- Availability and Quality of Grief and Bereavement Care in Pediatric Intensive Care Units Around the World, Opportunities for ImprovementGrunauer M, Mikesell C, Bustamante G, Aronowitz D, Zambrano K, Icaza-Freire A, Gavilanes A, Barrera R, Group T, González J, López-Herce J, Rossetti E, Fabrizio C, Karam O, Saint-Faust M, Biban P, Carlassara S, von Dessauer B, Ordenes N, Urízar F, A A, Canarie M, Miller K, Irazuzta J, Tawfik D, Tucker E, Shilkofski N, Wenchao W, Yuxia Z, See L, Priscilla, Tekin R, Aktar F, Düzkaya D, Dursun O, Ongun E, Yilmaz R, Yildizdas D, Tekgüç H, Sazonov V, Tsoy T, Sazonov V, Saparov A, Sazonov V, Kalmbakh E, Grunauer M, Quiñones E, Eguiguren L, Briones K, Tovilla Y, Gómez S, Torres S, Cobarrubias P, Dmytriiev D, Martínez A, Guzaman G, Sanabria R, Krupanandan R, Ramachandran B, Choraria N, Patel J, Pooni P, Gill K, Appiah J, Heye T, Argaw R, Demtse A, Admasu I. Availability and Quality of Grief and Bereavement Care in Pediatric Intensive Care Units Around the World, Opportunities for Improvement Frontiers In Pediatrics 2021, 9: 742916. PMID: 34869100, PMCID: PMC8634722, DOI: 10.3389/fped.2021.742916.
- Epidemiology of Bleeding in Critically Ill Children With an Underlying Oncologic DiagnosisRomano J, Martinez M, Levasseur J, Killinger JS, Karam O, Nellis ME. Epidemiology of Bleeding in Critically Ill Children With an Underlying Oncologic Diagnosis Critical Care Explorations 2021, 3: e0572. PMID: 34746797, PMCID: PMC8565795, DOI: 10.1097/cce.0000000000000572.
- Pain Assessment and Management in Pediatric Intensive Care Units Around the World, an International, Multicenter StudyGrunauer M, Mikesell C, Bustamante G, Cobo G, Sánchez S, Román A, Icaza-Freire A, Gavilanes A, Wang N, Group T, González J, López-Herce J, Rossetti E, Fabrizio C, Karam O, Saint-Faust M, Biban P, Carlassara S, von Dessauer B, Ordenes N, Urízar F, A A, Canarie M, Miller K, Irazuzta J, Chiriboga N, Tawfik D, Sourkes B, Wang N, Vongsachang H, Tucker E, Shilkofski N, Wang 王, Wenchao R, RN Z, See L, Priscilla, Tekin R, Aktar F, Düzkaya D, Dursun O, Ongun E, Yilmaz R, Yildizdas D, Tekgüç H, Sazonov V, Tsoy T, Sazonov V, Saparov A, Sazonov V, Kalmbakh E, Grunauer M, Eguiguren L, Claudette K, Tovilla Y, Gómez S, Torres S, Cobarrubias P, Dmytriiev D, Martínez A, Guzaman G, Sanabria R, Krupanandan R, Ramachandran B, Choraria N, Patel J, Pooni P, Gill K, Appiah J, Anokye K, Heye T, Argaw R, Demtse A, Admasu I. Pain Assessment and Management in Pediatric Intensive Care Units Around the World, an International, Multicenter Study Frontiers In Pediatrics 2021, 9: 746489. PMID: 34778135, PMCID: PMC8581242, DOI: 10.3389/fped.2021.746489.
- Transfusion practices for pediatric oncology and hematopoietic stem cell transplantation patients: Data from the National Heart Lung and Blood Institute Recipient Epidemiology and Donor Evaluation Study‐III (REDS‐III)Goel R, Nellis ME, Karam O, Hanson SJ, Tormey CA, Patel RM, Birch R, Sachais BS, Sola‐Visner M, Hauser RG, Luban NLC, Gottschall J, Josephson CD, Hendrickson JE, Karafin MS, Study‐IV‐Pediatric F. Transfusion practices for pediatric oncology and hematopoietic stem cell transplantation patients: Data from the National Heart Lung and Blood Institute Recipient Epidemiology and Donor Evaluation Study‐III (REDS‐III) Transfusion 2021, 61: 2589-2600. PMID: 34455598, DOI: 10.1111/trf.16626.
- Epidemiology of Bleeding in Critically Ill ChildrenSequeira J, Nellis ME, Karam O. Epidemiology of Bleeding in Critically Ill Children Frontiers In Pediatrics 2021, 9: 699991. PMID: 34422724, PMCID: PMC8371326, DOI: 10.3389/fped.2021.699991.
- Transfusion Practices in Pediatric Cardiac Surgery Requiring Cardiopulmonary Bypass: A Secondary Analysis of a Clinical Database.Hanson SJ, Karam O, Birch R, Goel R, Patel RM, Sola-Visner M, Sachais BS, Hauser RG, Luban NLC, Gottschall J, Josephson CD, Hendrickson JE, Karafin MS, Nellis ME. Transfusion Practices in Pediatric Cardiac Surgery Requiring Cardiopulmonary Bypass: A Secondary Analysis of a Clinical Database. Pediatric Critical Care Medicine 2021, 22: 978-987. PMID: 34261944, PMCID: PMC8570986, DOI: 10.1097/pcc.0000000000002805.
- Editorial: Hemostatic Challenges in Pediatric Critical Care MedicineCrighton GL, Karam O, Nellis ME, Stanworth SJ. Editorial: Hemostatic Challenges in Pediatric Critical Care Medicine Frontiers In Pediatrics 2021, 9: 697921. PMID: 34322464, PMCID: PMC8311020, DOI: 10.3389/fped.2021.697921.
- Performance of Platelet Mass Index as a Marker of Severity for Sepsis and Septic Shock in ChildrenChegondi M, Vijayakumar N, Billa R, Badheka A, Karam O. Performance of Platelet Mass Index as a Marker of Severity for Sepsis and Septic Shock in Children Journal Of Pediatric Intensive Care 2021 DOI: 10.1055/s-0041-1731434.
- Factors Associated With Initiation of Extracorporeal Cardiopulmonary Resuscitation in the Pediatric Population: An International SurveyNguyen DA, De Mul A, Hoskote AU, Cogo P, da Cruz EM, Erickson S, Lasa JJ, Thiagarajan RR, Bembea MM, Karam O. Factors Associated With Initiation of Extracorporeal Cardiopulmonary Resuscitation in the Pediatric Population: An International Survey ASAIO Journal 2021, 68: 413-418. PMID: 34074851, DOI: 10.1097/mat.0000000000001495.
- Transfusion practices in a large cohort of hospitalized childrenNellis ME, Goel R, Hendrickson JE, Birch R, Patel RM, Karafin MS, Hanson SJ, Sachais BS, Hauser RG, Luban NLC, Gottschall J, Sola‐Visner M, Josephson CD, Karam O, Study‐IV‐Pediatric F. Transfusion practices in a large cohort of hospitalized children Transfusion 2021, 61: 2042-2053. PMID: 33973660, DOI: 10.1111/trf.16443.
- Compliance With an Antibiotic Guideline for Suspected Ventilator-Associated Infection: The Ventilator-Associated INfection (VAIN2) Study.Karsies T, Tarquinio K, Shein SL, Beardsley AL, Prentice E, Karam O, Fontela P, Moore-Clingenpeel M, Willson DF. Compliance With an Antibiotic Guideline for Suspected Ventilator-Associated Infection: The Ventilator-Associated INfection (VAIN2) Study. Pediatric Critical Care Medicine 2021, 22: 859-869. PMID: 33965989, DOI: 10.1097/pcc.0000000000002761.
- Epidemiology of the Use of Hemostatic Agents in Children Supported by Extracorporeal Membrane Oxygenation: A Pediatric Health Information System Database StudyNellis ME, Vasovic LV, Goel R, Karam O. Epidemiology of the Use of Hemostatic Agents in Children Supported by Extracorporeal Membrane Oxygenation: A Pediatric Health Information System Database Study Frontiers In Pediatrics 2021, 9: 673613. PMID: 34041211, PMCID: PMC8141845, DOI: 10.3389/fped.2021.673613.
- Variation in Neonatal Transfusion PracticePatel RM, Hendrickson JE, Nellis ME, Birch R, Goel R, Karam O, Karafin MS, Hanson SJ, Sachais BS, Hauser RG, Luban NLC, Gottschall J, Josephson CD, Sola-Visner M, National Heart L, Mast A, Hod E, Custer B, Vichinsky E, Spencer B, Mathew S, Harris D, Busch M, Norris P, Ness P, Kleinman S, Tamburro R, Glynn S, Malkin K. Variation in Neonatal Transfusion Practice The Journal Of Pediatrics 2021, 235: 92-99.e4. PMID: 33836184, PMCID: PMC8316298, DOI: 10.1016/j.jpeds.2021.04.002.
- Lung Ultrasound versus Chest X-Ray for the Detection of Fluid Overload in Critically Ill Children: A Systematic ReviewSchapka E, Gee J, Cyrus JW, Goldstein G, Greenfield K, Marinello M, Karam O. Lung Ultrasound versus Chest X-Ray for the Detection of Fluid Overload in Critically Ill Children: A Systematic Review Journal Of Pediatric Intensive Care 2021, 11: 177-182. PMID: 35928036, PMCID: PMC9345674, DOI: 10.1055/s-0041-1725123.
- O050 / #605: EPIDEMIOLOGY OF HEMOSTATIC BLOOD PRODUCTS AND MEDICATIONS IN CHILDREN SUPPORTED BY EXTRACORPOREAL MEMBRANE OXYGENATIONKaram O, Vasovic L, Goel R, Joashi U, Nellis M. O050 / #605: EPIDEMIOLOGY OF HEMOSTATIC BLOOD PRODUCTS AND MEDICATIONS IN CHILDREN SUPPORTED BY EXTRACORPOREAL MEMBRANE OXYGENATION Pediatric Critical Care Medicine 2021, 22: 31-31. DOI: 10.1097/01.pcc.0000738304.68952.41.
- P0244 / #1602: ANTI-XA VERSUS TIME-GUIDED ANTICOAGULATION STRATEGY IN EXTRACORPOREAL MEMBRANE OXYGENATION: A SYSTEMATIC REVIEW AND META-ANALYSISWillems A, Roeleveld P, Nellis M, Labarinas S, Muszynski J, Cyrus J, Karam O. P0244 / #1602: ANTI-XA VERSUS TIME-GUIDED ANTICOAGULATION STRATEGY IN EXTRACORPOREAL MEMBRANE OXYGENATION: A SYSTEMATIC REVIEW AND META-ANALYSIS Pediatric Critical Care Medicine 2021, 22: 142-142. DOI: 10.1097/01.pcc.0000739320.11353.7f.
- P0253 / #1874: FACTORS ASSOCIATED WITH INITIATION OF EXTRACORPOREAL CARDIOPULMONARY RESUSCITATION IN THE PEDIATRIC POPULATION: AN INTERNATIONAL SURVEYNguyen D, De Mul A, Hoskote A, Cogo P, Da Cruz E, Erickson S, Lasa J, Thiagarajan R, Bembea M, Karam O. P0253 / #1874: FACTORS ASSOCIATED WITH INITIATION OF EXTRACORPOREAL CARDIOPULMONARY RESUSCITATION IN THE PEDIATRIC POPULATION: AN INTERNATIONAL SURVEY Pediatric Critical Care Medicine 2021, 22: 145-145. DOI: 10.1097/01.pcc.0000739352.15763.6e.
- A new tool to assess Clinical Diversity In Meta‐analyses (CDIM) of interventionsBarbateskovic M, Koster TM, Eck RJ, Maagaard M, Afshari A, Blokzijl F, Cronhjort M, Dieperink W, Fabritius ML, Feinberg J, French C, Gareb B, Geisler A, Granholm A, Hiemstra B, Hu R, Imberger G, Jensen BT, Jonsson AB, Karam O, Kong Z, Korang SK, Koster G, Lai B, Liang N, Lundstrøm LH, Marker S, Meyhoff TS, Nielsen EE, Nørskov AK, Munch MW, Risom EC, Rygård SL, Safi S, Sethi N, Sjövall F, Lauridsen SV, van Bakelen N, Volbeda M, van der Horst ICC, Gluud C, Perner A, Møller MH, Keus E, Wetterslev J. A new tool to assess Clinical Diversity In Meta‐analyses (CDIM) of interventions Journal Of Clinical Epidemiology 2021, 135: 29-41. PMID: 33561529, DOI: 10.1016/j.jclinepi.2021.01.023.
- Bleeding in Critically Ill Children—Review of Literature, Knowledge Gaps, and Suggestions for Future InvestigationAran AA, Karam O, Nellis ME. Bleeding in Critically Ill Children—Review of Literature, Knowledge Gaps, and Suggestions for Future Investigation Frontiers In Pediatrics 2021, 9: 611680. PMID: 33585373, PMCID: PMC7873638, DOI: 10.3389/fped.2021.611680.
- Transfusion management for children supported by extracorporeal membrane oxygenationKaram O, Nellis ME. Transfusion management for children supported by extracorporeal membrane oxygenation Transfusion 2021, 61: 660-664. PMID: 33491189, DOI: 10.1111/trf.16272.
- 496: Epidemiology of Bleeding in Critically Ill ChildrenSequeira J, Karam O, Nellis M. 496: Epidemiology of Bleeding in Critically Ill Children Critical Care Medicine 2020, 49: 239-239. DOI: 10.1097/01.ccm.0000727872.28935.ab.
- 498: Bleeding in Critically Ill Children With Underlying Oncologic DiagnosesLevasseur J, Fikse L, Mauguen A, Killinger J, Karam O, Nellis M. 498: Bleeding in Critically Ill Children With Underlying Oncologic Diagnoses Critical Care Medicine 2020, 49: 240-240. DOI: 10.1097/01.ccm.0000727880.44510.37.
- 1213: Platelet Mass Index as Prognostic Marker in Pediatric Septic ShockChegondi M, Vijayakumar N, Badheka A, Karam O. 1213: Platelet Mass Index as Prognostic Marker in Pediatric Septic Shock Critical Care Medicine 2020, 49: 610-610. DOI: 10.1097/01.ccm.0000730740.44907.64.
- Ketamine Boluses Decrease Intracranial Pressure and Improve Cerebral Perfusion Pressure in Patients with Severe Traumatic Brain InjuryDengler B, Karam O, Barthol C, Hafeez S. Ketamine Boluses Decrease Intracranial Pressure and Improve Cerebral Perfusion Pressure in Patients with Severe Traumatic Brain Injury Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_450.
- Overview of Plasma and Platelet Transfusions in Critically Ill ChildrenKahn S, Chegondi M, Nellis ME, Karam O. Overview of Plasma and Platelet Transfusions in Critically Ill Children Frontiers In Pediatrics 2020, 8: 601659. PMID: 33282804, PMCID: PMC7691248, DOI: 10.3389/fped.2020.601659.
- Brighter Days May Be Ahead: Continuous Measurement of Pediatric Intensive Care Unit Light and SoundGreenfield KD, Karam O, O'Meara A. Brighter Days May Be Ahead: Continuous Measurement of Pediatric Intensive Care Unit Light and Sound Frontiers In Pediatrics 2020, 8: 590715. PMID: 33194924, PMCID: PMC7649178, DOI: 10.3389/fped.2020.590715.
- Effect of platelet storage duration on clinical outcomes and incremental platelet change in critically ill childrenNellis ME, Spinella PC, Tucci M, Stanworth SJ, Steiner ME, Cushing MM, Davis PJ, Karam O, The Pediatric Acute Lung Injury and Sepsis Investigators network P. Effect of platelet storage duration on clinical outcomes and incremental platelet change in critically ill children Transfusion 2020, 60: 2849-2858. PMID: 32959409, PMCID: PMC8396066, DOI: 10.1111/trf.16094.
- Anti-Xa versus time-guided anticoagulation strategies in extracorporeal membrane oxygenation: a systematic review and meta-analysisWillems A, Roeleveld PP, Labarinas S, Cyrus JW, Muszynski JA, Nellis ME, Karam O. Anti-Xa versus time-guided anticoagulation strategies in extracorporeal membrane oxygenation: a systematic review and meta-analysis Perfusion 2020, 36: 501-512. PMID: 32862767, PMCID: PMC8216320, DOI: 10.1177/0267659120952982.
- Designing Appropriate and Individualized Transfusion Strategies: Finding the Sweet Spot.Demaret P, Karam O. Designing Appropriate and Individualized Transfusion Strategies: Finding the Sweet Spot. Pediatric Critical Care Medicine 2020, 21: 770-772. PMID: 32769943, DOI: 10.1097/pcc.0000000000002369.
- Preoperative erythropoietin within a patient blood management program decreases both blood transfusion and postoperative anemia: a prospective observational studyBiboulet P, Motais C, Pencole M, Karam O, Dangelser G, Smilevitch P, Maissiat G, Capdevila X, Bringuier S. Preoperative erythropoietin within a patient blood management program decreases both blood transfusion and postoperative anemia: a prospective observational study Transfusion 2020, 60: 1732-1740. PMID: 32681743, DOI: 10.1111/trf.15900.
- Individual‐ and hospital‐level correlates of red blood cell, platelet, and plasma transfusions among hospitalized children and neonates: a nationally representative study in the United StatesGoel R, Josephson CD, Patel EU, Petersen MR, Packman Z, Gehrie E, Bloch EM, Lokhandwala P, Ness PM, Katz L, Nellis M, Karam O, Tobian AAR. Individual‐ and hospital‐level correlates of red blood cell, platelet, and plasma transfusions among hospitalized children and neonates: a nationally representative study in the United States Transfusion 2020, 60: 1700-1712. PMID: 32589286, PMCID: PMC7951993, DOI: 10.1111/trf.15855.
- Association Between Lactates, Blood Glucose, and Systemic Oxygen Delivery in Children After Cardiopulmonary BypassKlee P, Rimensberger PC, Karam O. Association Between Lactates, Blood Glucose, and Systemic Oxygen Delivery in Children After Cardiopulmonary Bypass Frontiers In Pediatrics 2020, 8: 332. PMID: 32656170, PMCID: PMC7325592, DOI: 10.3389/fped.2020.00332.
- Epidemiology of Hemostatic Transfusions in Children Supported by Extracorporeal Membrane Oxygenation.Karam O, Goel R, Dalton H, Nellis ME. Epidemiology of Hemostatic Transfusions in Children Supported by Extracorporeal Membrane Oxygenation. Critical Care Medicine 2020, 48: e698-e705. PMID: 32697511, DOI: 10.1097/ccm.0000000000004417.
- Pleural Effusions After Congenital Cardiac Surgery Requiring Readmission: A Systematic Review and Meta-analysisHughes A, Carter K, Cyrus J, Karam O. Pleural Effusions After Congenital Cardiac Surgery Requiring Readmission: A Systematic Review and Meta-analysis Pediatric Cardiology 2020, 41: 1145-1152. PMID: 32424719, DOI: 10.1007/s00246-020-02365-4.
- Association Between Lactates, Blood Glucose, and Oxygen Extraction in Critically Ill Children After Cardiopulmonary BypassKaram O, Klee P, Rimensberger P. Association Between Lactates, Blood Glucose, and Oxygen Extraction in Critically Ill Children After Cardiopulmonary Bypass 2020, a6311-a6311. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6311.
- Hemostatic Transfusions in Children Supported by Extracorporeal Membrane OxygenationKaram O, Goel R, Dalton H, Nellis M. Hemostatic Transfusions in Children Supported by Extracorporeal Membrane Oxygenation 2020, a1742-a1742. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1742.
- Potential Neurodevelopmental Effects of Pediatric Intensive Care Sedation and Analgesia: Repetitive Benzodiazepine and Opioid Exposure Alters Expression of Glial and Synaptic Proteins in Juvenile RatsIqbal O'Meara AM, Miller Ferguson N, Zven SE, Karam OL, Meyer LC, Bigbee JW, Sato-Bigbee C. Potential Neurodevelopmental Effects of Pediatric Intensive Care Sedation and Analgesia: Repetitive Benzodiazepine and Opioid Exposure Alters Expression of Glial and Synaptic Proteins in Juvenile Rats Critical Care Explorations 2020, 2: e0105. PMID: 32426747, PMCID: PMC7188419, DOI: 10.1097/cce.0000000000000105.
- Perioperative Transfusions and Venous ThromboembolismGoel R, Josephson CD, Patel EU, Petersen MR, Makhani S, Frank SM, Ness PM, Bloch EM, Gehrie EA, Lokhandwala PM, Nellis MM, Karam O, Shaz BH, Patel RM, Tobian AAR. Perioperative Transfusions and Venous Thromboembolism Pediatrics 2020, 145: e20192351. PMID: 32198293, PMCID: PMC7111487, DOI: 10.1542/peds.2019-2351.
- How 217 Pediatric Intensivists Manage Anemia at PICU Discharge: Online Responses to an International Survey.Demaret P, Karam O, Labreuche Bst J, Chiusolo F, Mayordomo Colunga J, Erickson S, Nellis ME, Perez MH, Ray S, Tucci M, Willems A, Duhamel A, Lebrun F, Loeckx I, Mulder A, Leteurtre S. How 217 Pediatric Intensivists Manage Anemia at PICU Discharge: Online Responses to an International Survey. Pediatric Critical Care Medicine 2020, 21: e342-e353. PMID: 32217901, DOI: 10.1097/pcc.0000000000002307.
- Pediatric Plasma and Platelet Transfusions on Extracorporeal Membrane Oxygenation: A Subgroup Analysis of Two Large International Point-Prevalence Studies and the Role of Local Guidelines.Nellis ME, Saini A, Spinella PC, Davis PJ, Steiner ME, Tucci M, Cushing M, Demaret P, Stanworth SJ, Leteurtre S, Karam O. Pediatric Plasma and Platelet Transfusions on Extracorporeal Membrane Oxygenation: A Subgroup Analysis of Two Large International Point-Prevalence Studies and the Role of Local Guidelines. Pediatric Critical Care Medicine 2020, 21: 267-275. PMID: 31644453, PMCID: PMC7060816, DOI: 10.1097/pcc.0000000000002160.
- Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in childrenWeiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children Intensive Care Medicine 2020, 46: 1-9. PMID: 32030528, DOI: 10.1007/s00134-019-05877-7.
- Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in childrenWeiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children Intensive Care Medicine 2020, 46: 10-67. PMID: 32030529, PMCID: PMC7095013, DOI: 10.1007/s00134-019-05878-6.
- Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatric Critical Care Medicine 2020, 21: 186-195. PMID: 32032264, DOI: 10.1097/pcc.0000000000002197.
- Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatric Critical Care Medicine 2020, 21: e52-e106. PMID: 32032273, DOI: 10.1097/pcc.0000000000002198.
- 503: EFFECT OF PLATELET TRANSFUSIONS ON EXTRACORPOREAL LIFE SUPPORT OXYGENATOR FUNCTIONChegondi M, Badheka A, Karam O. 503: EFFECT OF PLATELET TRANSFUSIONS ON EXTRACORPOREAL LIFE SUPPORT OXYGENATOR FUNCTION Critical Care Medicine 2020, 48: 232-232. DOI: 10.1097/01.ccm.0000620356.85007.e7.
- Bleeding Assessment Scale in Critically Ill Children (BASIC): Physician-Driven Diagnostic Criteria for Bleeding Severity.Nellis ME, Tucci M, Lacroix J, Spinella PC, Haque KD, Stock A, Steiner ME, Faustino EVS, Zantek ND, Davis PJ, Stanworth SJ, Cholette JM, Parker RI, Demaret P, Kneyber MCJ, Russell RT, Stricker PA, Vogel AM, Willems A, Josephson CD, Luban NLC, Loftis LL, Leteurtre S, Stocker CF, Goobie SM, Karam O. Bleeding Assessment Scale in Critically Ill Children (BASIC): Physician-Driven Diagnostic Criteria for Bleeding Severity. Critical Care Medicine 2019, 47: 1766-1772. PMID: 31567407, PMCID: PMC6861687, DOI: 10.1097/ccm.0000000000004025.
- Quantifiable Bleeding in Children Supported by Extracorporeal Membrane Oxygenation and Outcome.Nellis ME, Dalton H, Karam O. Quantifiable Bleeding in Children Supported by Extracorporeal Membrane Oxygenation and Outcome. Critical Care Medicine 2019, 47: e886-e892. PMID: 31449061, PMCID: PMC8608374, DOI: 10.1097/ccm.0000000000003968.
- Transfusion in children with acute respiratory distress syndrome.François T, Emeriaud G, Karam O, Tucci M. Transfusion in children with acute respiratory distress syndrome. Annals Of Translational Medicine 2019, 7: 511. PMID: 31728364, PMCID: PMC6828792, DOI: 10.21037/atm.2019.08.28.
- Anemia at Discharge From the PICU: A Bicenter Descriptive Study.Demaret P, Valla FV, Behal H, Mimouni Y, Baudelet JB, Karam O, Recher M, Duhamel A, Tucci M, Javouhey E, Leteurtre S. Anemia at Discharge From the PICU: A Bicenter Descriptive Study. Pediatric Critical Care Medicine 2019, 20: e400-e409. PMID: 31246740, DOI: 10.1097/pcc.0000000000002015.
- Development of an Antibiotic Guideline for Children With Suspected Ventilator-Associated Infections.Shein SL, Karam O, Beardsley A, Karsies T, Prentice E, Tarquinio KM, Willson DF. Development of an Antibiotic Guideline for Children With Suspected Ventilator-Associated Infections. Pediatric Critical Care Medicine 2019, 20: 697-706. PMID: 30985606, DOI: 10.1097/pcc.0000000000001942.
- Reply to: Prognostic Evaluation of Mortality after Pediatric Resuscitation Assisted by Extracorporeal Life SupportDoell C, De Mul A, Nguyen DA, Perez MH, Karam O, Cannizzaro V. Reply to: Prognostic Evaluation of Mortality after Pediatric Resuscitation Assisted by Extracorporeal Life Support Journal Of Pediatric Intensive Care 2019, 08: 193-194. PMID: 31404921, PMCID: PMC6687445, DOI: 10.1055/s-0039-1692969.
- Transfusion Management in Pediatric Oncology PatientsNellis ME, Goel R, Karam O. Transfusion Management in Pediatric Oncology Patients Hematology/Oncology Clinics Of North America 2019, 33: 903-913. PMID: 31466612, DOI: 10.1016/j.hoc.2019.05.011.
- Bleeding Scales Applicable to Critically Ill Children: A Systematic Review.Nellis ME, Levasseur J, Stribling J, Faustino EVS, Zantek ND, Sheth S, Karam O. Bleeding Scales Applicable to Critically Ill Children: A Systematic Review. Pediatric Critical Care Medicine 2019, 20: 603-607. PMID: 30925573, DOI: 10.1097/pcc.0000000000001943.
- International Study of the Epidemiology of Platelet Transfusions in Critically Ill Children With an Underlying Oncologic Diagnosis.Nellis ME, Goel R, Karam O, Cushing MM, Davis PJ, Steiner ME, Tucci M, Stanworth SJ, Spinella PC. International Study of the Epidemiology of Platelet Transfusions in Critically Ill Children With an Underlying Oncologic Diagnosis. Pediatric Critical Care Medicine 2019, 20: e342-e351. PMID: 31107379, DOI: 10.1097/pcc.0000000000001987.
- Criteria for Clinically Relevant Bleeding in Critically Ill ChildrenKaram O, Nellis ME, Zantek ND, Lacroix J, Faustino EVS. Criteria for Clinically Relevant Bleeding in Critically Ill Children Pediatric Critical Care Medicine 2019, Publish Ahead of Print: &na;. PMID: 30575698, DOI: 10.1097/pcc.0000000000001828.
- Effects of Blindfold on Leadership in Pediatric Resuscitation Simulation: A Randomized TrialBuyck M, Manzano S, Haddad K, Moncousin AC, Galetto-Lacour A, Blondon K, Karam O. Effects of Blindfold on Leadership in Pediatric Resuscitation Simulation: A Randomized Trial Frontiers In Pediatrics 2019, 7: 10. PMID: 30838188, PMCID: PMC6383074, DOI: 10.3389/fped.2019.00010.
- Effects of ABO Matching of Platelet Transfusions in Critically Ill Children*Nellis ME, Goel R, Karam O, Cushing MM, Davis PJ, Steiner ME, Tucci M, Stanworth SJ, Spinella PC. Effects of ABO Matching of Platelet Transfusions in Critically Ill Children* Pediatric Critical Care Medicine 2019, 20: e61-e69. PMID: 30422914, PMCID: PMC6709973, DOI: 10.1097/pcc.0000000000001779.
- 511Saini A, Nellis M, Davis P, Spinella P, Karam O. 511 Critical Care Medicine 2019, 47: 236. DOI: 10.1097/01.ccm.0000551263.36275.d3.
- 512Saini A, Nellis M, Davis P, Spinella P, Karam O. 512 Critical Care Medicine 2019, 47: 236. DOI: 10.1097/01.ccm.0000551264.74392.25.
- 1390Greenfield K, Karam O, O’Meara A. 1390 Critical Care Medicine 2019, 47: 671. DOI: 10.1097/01.ccm.0000552134.59636.77.
- International survey on anticoagulation and antiplatelet strategies after pediatric liver transplantationCalinescu AM, Karam O, Wilde JCH, Ansari M, McLin VA, Wildhaber BE. International survey on anticoagulation and antiplatelet strategies after pediatric liver transplantation Pediatric Transplantation 2018, 23: e13317. PMID: 30393923, DOI: 10.1111/petr.13317.
- International, multicentre, observational study of fluid bolus therapy in neonatesKeir AK, Karam O, Hodyl N, Stark MJ, Liley HG, Shah PS, Stanworth SJ, Group O. International, multicentre, observational study of fluid bolus therapy in neonates Journal Of Paediatrics And Child Health 2018, 55: 632-639. PMID: 30328174, DOI: 10.1111/jpc.14260.
- Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise InitiativeValentine SL, Bembea MM, Muszynski JA, Cholette JM, Doctor A, Spinella PC, Steiner ME, Tucci M, Hassan NE, Parker RI, Lacroix J, Argent A, Carson JL, Remy KE, Demaret P, Emeriaud G, Kneyber MCJ, Guzzetta N, Hall MW, Macrae D, Karam O, Russell RT, Stricker PA, Vogel AM, Tasker RC, Turgeon AF, Schwartz SM, Willems A, Josephson CD, Luban NLC, Lehmann LE, Stanworth SJ, Zantek ND, Bunchman TE, Cheifetz IM, Fortenberry JD, Delaney M, van de Watering L, Robinson KA, Malone S, Steffen KM, Bateman ST. Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative Pediatric Critical Care Medicine 2018, 19: 884-898. PMID: 30180125, PMCID: PMC6126913, DOI: 10.1097/pcc.0000000000001613.
- Recommendations on RBC Transfusion in Critically Ill Children With Nonlife-Threatening Bleeding or Hemorrhagic Shock From the Pediatric Critical Care Transfusion and Anemia Expertise InitiativeKaram O, Russell RT, Stricker P, Vogel AM, Bateman ST, Valentine SL, Spinella PC. Recommendations on RBC Transfusion in Critically Ill Children With Nonlife-Threatening Bleeding or Hemorrhagic Shock From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative Pediatric Critical Care Medicine 2018, 19: s127-s132. PMID: 30161067, PMCID: PMC6121734, DOI: 10.1097/pcc.0000000000001605.
- Platelet Transfusion Practices in Critically Ill ChildrenNellis ME, Karam O, Mauer E, Cushing MM, Davis PJ, Steiner ME, Tucci M, Stanworth SJ, Spinella PC. Platelet Transfusion Practices in Critically Ill Children Critical Care Medicine 2018, 46: 1309-1317. PMID: 29727368, PMCID: PMC6476545, DOI: 10.1097/ccm.0000000000003192.
- Prognostic Evaluation of Mortality after Pediatric Resuscitation Assisted by Extracorporeal Life SupportDe Mul A, Nguyen DA, Doell C, Perez MH, Cannizzaro V, Karam O. Prognostic Evaluation of Mortality after Pediatric Resuscitation Assisted by Extracorporeal Life Support Journal Of Pediatric Intensive Care 2018, 08: 057-063. PMID: 31093456, PMCID: PMC6517051, DOI: 10.1055/s-0038-1667012.
- CEREBRAL OXYGENATION AND PERIPHERAL OXIMETRY IN EXTREMELY PRETERM INFANTS WITH PULMONARY AND/OR CEREBRAL INTRAVENTRICULAR HEMORRHAGE IN THE FIRST 72 HOURS OF LIFEBeausoleil T, Janaillac M, Barrington K, Raboisson M, Karam O, Lapointe A, Dehaes M. CEREBRAL OXYGENATION AND PERIPHERAL OXIMETRY IN EXTREMELY PRETERM INFANTS WITH PULMONARY AND/OR CEREBRAL INTRAVENTRICULAR HEMORRHAGE IN THE FIRST 72 HOURS OF LIFE Paediatrics & Child Health 2018, 23: e22-e23. PMCID: PMC5961098, DOI: 10.1093/pch/pxy054.056.
- RELATIONSHIPS BETWEEN NEAR-INFRARED SPECTROSCOPY, PREDUCTAL PERFUSION INDEX AND CARDIAC OUTPUTS IN EXTREMELY PRETERM INFANTS IN THE FIRST 72 HOURS OF LIFEJanaillac M, Beausoleil T, Karam O, Raboisson M, Barrington K, Dehaes M, Lapointe A. RELATIONSHIPS BETWEEN NEAR-INFRARED SPECTROSCOPY, PREDUCTAL PERFUSION INDEX AND CARDIAC OUTPUTS IN EXTREMELY PRETERM INFANTS IN THE FIRST 72 HOURS OF LIFE Paediatrics & Child Health 2018, 23: e23-e24. PMCID: PMC5961382, DOI: 10.1093/pch/pxy054.059.
- Effects of plasma transfusions on antithrombin levels after paediatric liver transplantationArni D, Wildhaber BE, McLin V, Rimensberger PC, Ansari M, Fontana P, Karam O. Effects of plasma transfusions on antithrombin levels after paediatric liver transplantation Vox Sanguinis 2018, 113: 569-576. PMID: 29761839, DOI: 10.1111/vox.12664.
- Assessing our current practice: point prevalence studies in transfusion medicineNellis ME, Karam O. Assessing our current practice: point prevalence studies in transfusion medicine Transfusion 2018, 58: 843-845. PMID: 29380394, DOI: 10.1111/trf.14492.
- Correlations between near-infrared spectroscopy, perfusion index, and cardiac outputs in extremely preterm infants in the first 72 h of lifeJanaillac M, Beausoleil TP, Barrington KJ, Raboisson MJ, Karam O, Dehaes M, Lapointe A. Correlations between near-infrared spectroscopy, perfusion index, and cardiac outputs in extremely preterm infants in the first 72 h of life European Journal Of Pediatrics 2018, 177: 541-550. PMID: 29374830, DOI: 10.1007/s00431-018-3096-z.
- Diagnosis and Management of Necrotizing Enterocolitis: An International Survey of Neonatologists and Pediatric SurgeonsValpacos M, Arni D, Keir A, Aspirot A, Wilde JCH, Beasley S, De Luca D, Pfister RE, Karam O. Diagnosis and Management of Necrotizing Enterocolitis: An International Survey of Neonatologists and Pediatric Surgeons Neonatology 2017, 113: 170-176. PMID: 29241163, DOI: 10.1159/000484197.
- Perceived changes in behavior and values after a red blood cell transfusionBroccolo M, Favez N, Karam O. Perceived changes in behavior and values after a red blood cell transfusion International Journal Of Clinical Transfusion Medicine 2017, 6: 1-5. DOI: 10.2147/ijctm.s155338.
- Anemia at pediatric intensive care unit discharge: prevalence and risk markersDemaret P, Karam O, Tucci M, Lacroix J, Behal H, Duhamel A, Lebrun F, Mulder A, Leteurtre S. Anemia at pediatric intensive care unit discharge: prevalence and risk markers Annals Of Intensive Care 2017, 7: 107. PMID: 29067568, PMCID: PMC5655401, DOI: 10.1186/s13613-017-0328-8.
- A Quantitative Pilot Study on Donation after Cardiac Death (DCD)Zellweger A, Eckert P, Karam O, Cedraschi C, Moretti D, Majmou H, Carre D, Ludwig V, Gasche Y. A Quantitative Pilot Study on Donation after Cardiac Death (DCD) Transplantation 2017, 101: s21. DOI: 10.1097/01.tp.0000525002.75001.e9.
- Outcomes Related to the Use of Frozen Plasma or Pooled Solvent/Detergent-Treated Plasma in Critically Ill Children*Camazine MN, Karam O, Colvin R, Leteurtre S, Demaret P, Tucci M, Muszynski JA, Stanworth S, Spinella PC. Outcomes Related to the Use of Frozen Plasma or Pooled Solvent/Detergent-Treated Plasma in Critically Ill Children* Pediatric Critical Care Medicine 2017, 18: e215-e223. PMID: 28350560, DOI: 10.1097/pcc.0000000000001149.
- Rapid detection and ruling out of neonatal sepsis by PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS)Delcò C, Karam O, Pfister R, Gervaix A, Renzi G, Emonet S, Schrenzel J, Posfay-Barbe KM. Rapid detection and ruling out of neonatal sepsis by PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS) Early Human Development 2017, 108: 17-22. PMID: 28343091, DOI: 10.1016/j.earlhumdev.2017.03.004.
- Factors influencing plasma transfusion practices in paediatric intensive care units around the worldKaram O, Demaret P, Duhamel A, Shefler A, Spinella PC, Tucci M, Leteurtre S, Stanworth SJ, investigators T. Factors influencing plasma transfusion practices in paediatric intensive care units around the world Vox Sanguinis 2017, 112: 140-149. PMID: 28176380, DOI: 10.1111/vox.12490.
- Hypoglycemic relapse in term infants treated with glucose infusionSternberg J, Pfister R, Karam O. Hypoglycemic relapse in term infants treated with glucose infusion Journal Of Clinical Neonatology 2017, 6: 163-167. DOI: 10.4103/jcn.jcn_10_17.
- 603Labarinas S, Karam O. 603 Critical Care Medicine 2016, 44: 227. DOI: 10.1097/01.ccm.0000509280.64732.6a.
- The effect of inhaled nitric oxide in acute respiratory distress syndrome in children and adults: a Cochrane Systematic Review with trial sequential analysisKaram O, Gebistorf F, Wetterslev J, Afshari A. The effect of inhaled nitric oxide in acute respiratory distress syndrome in children and adults: a Cochrane Systematic Review with trial sequential analysis Anaesthesia 2016, 72: 106-117. PMID: 27762438, DOI: 10.1111/anae.13628.
- Effectiveness of a High-Fidelity Simulation-Based Training Program in Managing Cardiac Arrhythmias in Children: A Randomized Pilot Study.Bragard I, Farhat N, Seghaye MC, Karam O, Neuschwander A, Shayan Y, Schumacher K. Effectiveness of a High-Fidelity Simulation-Based Training Program in Managing Cardiac Arrhythmias in Children: A Randomized Pilot Study. Pediatric Emergency Care 2016, 35: 412-418. PMID: 27763955, DOI: 10.1097/pec.0000000000000931.
- Performance of the PEdiatric Logistic Organ Dysfunction-2 score in critically ill children requiring plasma transfusionsKaram O, Demaret P, Duhamel A, Shefler A, Spinella PC, Stanworth SJ, Tucci M, Leteurtre S, for the PlasmaTV investigators. Performance of the PEdiatric Logistic Organ Dysfunction-2 score in critically ill children requiring plasma transfusions Annals Of Intensive Care 2016, 6: 98. PMID: 27714707, PMCID: PMC5053948, DOI: 10.1186/s13613-016-0197-6.
- Are Scores Reliable in Predicting the Need for Surgery and Mortality in Necrotizing Enterocolitis?Arni D, Karam O, Vidal I, Rimensberger PC, Hanquinet S, Wildhaber BE. Are Scores Reliable in Predicting the Need for Surgery and Mortality in Necrotizing Enterocolitis? European Journal Of Pediatric Surgery 2016, 27: 330-335. PMID: 27706524, DOI: 10.1055/s-0036-1593382.
- Potential Pediatric Organ Donors After Cardiac DeathPregernig A, Karam O. Potential Pediatric Organ Donors After Cardiac Death Transplantation Proceedings 2016, 48: 2588-2591. PMID: 27788786, DOI: 10.1016/j.transproceed.2016.06.049.
- Ketosis After Cardiopulmonary Bypass in Children Is Associated With an Inadequate Balance Between Oxygen Transport and Consumption*Klee P, Arni D, Saudan S, Schwitzgebel VM, Sharma R, Karam O, Rimensberger PC. Ketosis After Cardiopulmonary Bypass in Children Is Associated With an Inadequate Balance Between Oxygen Transport and Consumption* Pediatric Critical Care Medicine 2016, 17: 852-859. PMID: 27472253, DOI: 10.1097/pcc.0000000000000880.
- Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adultsGebistorf F, Karam O, Wetterslev J, Afshari A. Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults Cochrane Database Of Systematic Reviews 2016, 2018: cd002787. PMID: 27347773, PMCID: PMC6464789, DOI: 10.1002/14651858.cd002787.pub3.
- Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature InfantsJanaillac M, Labarinas S, Pfister RE, Karam O. Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants Critical Care Research And Practice 2016, 2016: 8041967. PMID: 27375901, PMCID: PMC4916268, DOI: 10.1155/2016/8041967.
- Massive Transfusion in ChildrenKaram O, Tucci M. Massive Transfusion in Children Transfusion Medicine Reviews 2016, 30: 213-216. PMID: 27287298, DOI: 10.1016/j.tmrv.2016.05.010.
- Identifying Prognostic Criteria for Survival after Resuscitation Assisted by Extracorporeal Membrane OxygenationBrunner A, Dubois N, Rimensberger PC, Karam O. Identifying Prognostic Criteria for Survival after Resuscitation Assisted by Extracorporeal Membrane Oxygenation Critical Care Research And Practice 2016, 2016: 9521091. PMID: 27006826, PMCID: PMC4781941, DOI: 10.1155/2016/9521091.
- Molecular Adsorbent Recirculating System (MARS™ en réanimation pédiatriqueHagerman A, Karam O. Molecular Adsorbent Recirculating System (MARS™ en réanimation pédiatrique Médecine Intensive Réanimation 2016, 25: 239-245. DOI: 10.1007/s13546-015-1162-3.
- Donneurs d’organes potentiels aux soins intensifs pédiatriquesKaram O, Pregernig A. Donneurs d’organes potentiels aux soins intensifs pédiatriques Bioethica Forum 2016 DOI: 10.24894/bf.2016.09005.
- Rapid diagnosis to rule out bacterial bloodstream infection in neonatesDelco-Volonte C, Posfay-Barbe K, Karam O. Rapid diagnosis to rule out bacterial bloodstream infection in neonates Intensive Care Medicine Experimental 2015, 3: a298. PMCID: PMC4798179, DOI: 10.1186/2197-425x-3-s1-a298.
- Clinical Outcomes Associated With RBC Transfusions in Critically Ill ChildrenDemaret P, Tucci M, Karam O, Trottier H, Ducruet T, Lacroix J. Clinical Outcomes Associated With RBC Transfusions in Critically Ill Children Pediatric Critical Care Medicine 2015, 16: 505-514. PMID: 25905491, DOI: 10.1097/pcc.0000000000000423.
- Indications and Effects of Plasma Transfusions in Critically Ill ChildrenKaram O, Demaret P, Shefler A, Leteurtre S, Spinella PC, Stanworth SJ, Tucci M. Indications and Effects of Plasma Transfusions in Critically Ill Children American Journal Of Respiratory And Critical Care Medicine 2015, 191: 1395-1402. PMID: 25859890, DOI: 10.1164/rccm.201503-0450oc.
- Moderate and extended neonatal resuscitations occur in one in 10 births and require specialist cover 24 hours a dayTry A, Karam O, Delcò C, Kraemer K, Boulvain M, Pfister RE. Moderate and extended neonatal resuscitations occur in one in 10 births and require specialist cover 24 hours a day Acta Paediatrica 2015, 104: 589-595. PMID: 25619977, DOI: 10.1111/apa.12909.
- Primum Non Nocere*Karam O, Tucci M. Primum Non Nocere* Pediatric Critical Care Medicine 2015, 16: 189-190. PMID: 25647127, DOI: 10.1097/pcc.0000000000000326.
- New Generation Neonatal High Frequency Ventilators: Effect of Oscillatory Frequency and Working Principles on PerformanceGrazioli S, Karam O, Rimensberger PC. New Generation Neonatal High Frequency Ventilators: Effect of Oscillatory Frequency and Working Principles on Performance Respiratory Care 2014, 60: 363-370. PMID: 25406342, DOI: 10.4187/respcare.03048.
- Transfusions de plasma en réanimation pédiatriqueLabarinas S, Arni D, Karam O. Transfusions de plasma en réanimation pédiatrique Médecine Intensive Réanimation 2014, 23: 455-462. DOI: 10.1007/s13546-014-0900-2.
- Plasma transfusion strategies for critically ill patientsKaram O, Tucci M, Combescure C, Lacroix J, Rimensberger PC. Plasma transfusion strategies for critically ill patients Cochrane Database Of Systematic Reviews 2013, cd010654. PMID: 24374651, DOI: 10.1002/14651858.cd010654.pub2.
- Board 424 - Research Abstract Validation of a Tool for the Assessment of Trainees During Simulated Pediatric Resuscitation (Submission #967)Shayan Y, Gravel J, Bhanji F, Weiss M, Karam O, Manzano S, Bank I, Choker G, Levy A. Board 424 - Research Abstract Validation of a Tool for the Assessment of Trainees During Simulated Pediatric Resuscitation (Submission #967) Simulation In Healthcare The Journal Of The Society For Simulation In Healthcare 2013, 8: 593. DOI: 10.1097/01.sih.0000441676.11945.49.
- Patient–Ventilator Asynchrony During Noninvasive Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist in Infants and ChildrenVignaux L, Grazioli S, Piquilloud L, Bochaton N, Karam O, Levy-Jamet Y, Jaecklin T, Tourneux P, Jolliet P, Rimensberger PC. Patient–Ventilator Asynchrony During Noninvasive Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist in Infants and Children Pediatric Critical Care Medicine 2013, 14: e357-e364. PMID: 23863816, DOI: 10.1097/pcc.0b013e3182917922.
- Optimizing Patient-Ventilator Synchrony During Invasive Ventilator Assist in Children and Infants Remains a Difficult Task*Vignaux L, Grazioli S, Piquilloud L, Bochaton N, Karam O, Jaecklin T, Levy-Jamet Y, Tourneux P, Jolliet P, Rimensberger PC. Optimizing Patient-Ventilator Synchrony During Invasive Ventilator Assist in Children and Infants Remains a Difficult Task* Pediatric Critical Care Medicine 2013, 14: e316-e325. PMID: 23842584, DOI: 10.1097/pcc.0b013e31828a8606.
- Plasma Transfusion ThresholdsKaram O, Tucci M, Lacroix J, Rimensberger PC, Network C. Plasma Transfusion Thresholds Transfusion 2013, 54: 1125-1132. PMID: 24032693, DOI: 10.1111/trf.12393.
- Plasma transfusion strategies for critically ill patientsKaram O, Tucci M, Combescure C, Lacroix J, Rimensberger P. Plasma transfusion strategies for critically ill patients 2013 DOI: 10.1002/14651858.cd010654.
- Plasma in the PICU: why and when should we transfuse?Labarinas S, Arni D, Karam O. Plasma in the PICU: why and when should we transfuse? Annals Of Intensive Care 2013, 3: 16. PMID: 23725411, PMCID: PMC3698065, DOI: 10.1186/2110-5820-3-16.
- Association between plasma transfusions and clinical outcome in critically ill children: a prospective observational studyKaram O, Lacroix J, Robitaille N, Rimensberger PC, Tucci M. Association between plasma transfusions and clinical outcome in critically ill children: a prospective observational study Vox Sanguinis 2013, 104: 342-349. PMID: 23294337, DOI: 10.1111/vox.12009.
- 17 Red Blood Cell Transfusions in ChildrenKaram O. 17 Red Blood Cell Transfusions in Children Archives Of Disease In Childhood 2012, 97: a5. DOI: 10.1136/archdischild-2012-302724.0017.
- Mortality associated with restrictive threshold for red blood cell transfusion in pediatric patients with sepsisKaram O, Tucci M, Ducruet T, Hume H, Lacroix J, Gauvin F. Mortality associated with restrictive threshold for red blood cell transfusion in pediatric patients with sepsis Pediatric Critical Care Medicine 2012, 13: 495. DOI: 10.1097/pcc.0b013e31824fbefe.
- Red blood cell transfusion thresholds in pediatric patients with sepsis*Karam O, Tucci M, Ducruet T, Hume HA, Lacroix J, Gauvin F. Red blood cell transfusion thresholds in pediatric patients with sepsis* Pediatric Critical Care Medicine 2011, 12: 512-518. PMID: 21057356, DOI: 10.1097/pcc.0b013e3181fe344b.
- Long-distance air transport of an infant weighing less than 500 g: Is it in the patient’s best interest?Karam O, Roy M, Barrington K, Janvier A. Long-distance air transport of an infant weighing less than 500 g: Is it in the patient’s best interest? Paediatrics & Child Health 2011, 16: 79-81. PMID: 22294866, PMCID: PMC3043038, DOI: 10.1093/pch/16.2.79.
- Red blood cell transfusion thresholds in pediatric septic patientsKaram O, Tucci M, Ducruet T, Hume H, Lacroix J, Gauvin F. Red blood cell transfusion thresholds in pediatric septic patients Critical Care 2011, 15: p428. PMCID: PMC3068357, DOI: 10.1186/cc9848.
- Chapter 82 Transfusion MedicineLacroix J, Tucci M, Tinmouth A, Gauvin F, Karam O. Chapter 82 Transfusion Medicine 2011, 1162-1176. DOI: 10.1016/b978-0-323-07307-3.10082-5.
- National Survey on Abdominal Trauma Practices of Pediatric SurgeonsKaram1 O, Sanchez2 O, Wildhaber2 B, La Scala2 G. National Survey on Abdominal Trauma Practices of Pediatric Surgeons European Journal Of Pediatric Surgery 2010, 20: 334-338. PMID: 20976655, DOI: 10.1055/s-0030-1261885.
- Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patientsGauvin F, Spinella PC, Lacroix J, Choker G, Ducruet T, Karam O, Hébert PC, Hutchison JS, Hume HA, Tucci M, Network O. Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients Transfusion 2010, 50: 1902-1913. PMID: 20456697, DOI: 10.1111/j.1537-2995.2010.02661.x.
- Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational studyKaram O, Tucci M, Bateman ST, Ducruet T, Spinella PC, Randolph AG, Lacroix J. Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study Critical Care 2010, 14: r57. PMID: 20377853, PMCID: PMC2887178, DOI: 10.1186/cc8953.
- Length of storage and in vitro immunomodulation induced by prestorage leukoreduced red blood cellsKaram O, Tucci M, Toledano BJ, Robitaille N, Cousineau J, Thibault L, Lacroix J, Le Deist F. Length of storage and in vitro immunomodulation induced by prestorage leukoreduced red blood cells Transfusion 2009, 49: 2326-2334. PMID: 19624600, DOI: 10.1111/j.1537-2995.2009.02319.x.
- Effect of length of storage of red blood cell units on outcome in critically ill childrenKaram O, Tucci M, Bateman S, Ducruet T, Spinella P, Randolph A, Lacroix J. Effect of length of storage of red blood cell units on outcome in critically ill children Critical Care 2009, 13: p417. PMCID: PMC4084303, DOI: 10.1186/cc7581.
- Blunt abdominal trauma in children: a score to predict the absence of organ injuryKaram O, Sanchez O, Wildhaber B, Chardot C, La Scala G. Blunt abdominal trauma in children: a score to predict the absence of organ injury Critical Care 2009, 13: p421. PMCID: PMC4084307, DOI: 10.1186/cc7585.
- Blunt Abdominal Trauma in Children: A Score to Predict the Absence of Organ InjuryKaram O, Sanchez O, Chardot C, La Scala G. Blunt Abdominal Trauma in Children: A Score to Predict the Absence of Organ Injury The Journal Of Pediatrics 2009, 154: 912-917. PMID: 19230903, DOI: 10.1016/j.jpeds.2009.01.001.
- VGAM induced high-flow congestive heart failure responsive to PGE1 infusionKaram O, da Cruz E, Rimensberger PC. VGAM induced high-flow congestive heart failure responsive to PGE1 infusion International Journal Of Cardiology 2007, 132: e60-e62. PMID: 18022260, DOI: 10.1016/j.ijcard.2007.08.020.
- Liver Function Tests in Children with Blunt Abdominal TraumasKaram O, La Scala G, Le Coultre C, Chardot C. Liver Function Tests in Children with Blunt Abdominal Traumas European Journal Of Pediatric Surgery 2007, 17: 313-316. PMID: 17968786, DOI: 10.1055/s-2007-965533.
- Unilateral focal polymicrogyria in a patient with classical Aarskog-Scott syndrome due to a novel missense mutation in an evolutionary conserved RhoGEF domain of the faciogenital dysplasia gene FGD1.Bottani A, Orrico A, Galli L, Karam O, Haenggeli CA, Ferey S, Conrad B. Unilateral focal polymicrogyria in a patient with classical Aarskog-Scott syndrome due to a novel missense mutation in an evolutionary conserved RhoGEF domain of the faciogenital dysplasia gene FGD1. American Journal Of Medical Genetics. Part A 2007, 143A: 2334-8. PMID: 17847065, DOI: 10.1002/ajmg.a.31733.
- Noise levels during nCPAP are flow-dependent but not device-dependentKaram O, Donatiello C, Van Lancker E, Chritin V, Pfister RE, Rimensberger PC. Noise levels during nCPAP are flow-dependent but not device-dependent Archives Of Disease In Childhood - Fetal And Neonatal Edition 2007, 93: f132. PMID: 18089628, DOI: 10.1136/adc.2007.129098.
- Congenital lingual cystsKaram O, Pfister RE, Extermann P, La Scala GC. Congenital lingual cysts Journal Of Pediatric Surgery 2007, 42: e25-e27. PMID: 17448749, DOI: 10.1016/j.jpedsurg.2007.01.060.