Mengfei Liu
Assistant Professor of Medicine (Digestive Diseases)
Research & Publications
Biography
News
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Coauthors
Selected Publications
- Mechanotransduction-induced glycolysis epigenetically regulates a CXCL1-dominant angiocrine signaling program in liver sinusoidal endothelial cells in vitro and in vivoGreuter T, Yaqoob U, Gan C, Jalan-Sakrikar N, Kostallari E, Lu J, Gao J, Sun L, Liu M, Sehrawat TS, Ibrahim SH, Furuta K, Nozickova K, Huang BQ, Gao B, Simons M, Cao S, Shah VH. Mechanotransduction-induced glycolysis epigenetically regulates a CXCL1-dominant angiocrine signaling program in liver sinusoidal endothelial cells in vitro and in vivo. Journal Of Hepatology 2022, 77: 723-734. PMID: 35421427, PMCID: PMC9391258, DOI: 10.1016/j.jhep.2022.03.029.
- Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitisLiu M, Cao S, He L, Gao J, Arab J, Cui H, Xuan W, Gao Y, Sehrawat T, Hamdan F, Ventura-Cots M, Argemi J, Pomerantz W, Johnsen S, Lee J, Gao F, Ordog T, Mathurin P, Revzin A, Bataller R, Yan H, Shah V. Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis. Nature Communications 2021, 12: 4560. PMID: 34315876, PMCID: PMC8316465, DOI: 10.1038/s41467-021-24843-w.
- Endothelial p300 Promotes Portal Hypertension and Hepatic Fibrosis Through C‐C Motif Chemokine Ligand 2–Mediated Angiocrine SignalingGao J, Wei B, Liu M, Hirsova P, Sehrawat T, Cao S, Hu X, Xue F, Yaqoob U, Kang N, Cui H, Pomerantz W, Kostallari E, Shah V. Endothelial p300 Promotes Portal Hypertension and Hepatic Fibrosis Through C‐C Motif Chemokine Ligand 2–Mediated Angiocrine Signaling. Hepatology 2021, 73: 2468-2483. PMID: 33159815, PMCID: PMC8102654, DOI: 10.1002/hep.31617.
- Regulation and functional roles of chemokines in liver diseasesCao S, Liu M, Sehrawat T, Shah V. Regulation and functional roles of chemokines in liver diseases. Nature Reviews Gastroenterology & Hepatology 2021, 18: 630-647. PMID: 33976393, PMCID: PMC9036964, DOI: 10.1038/s41575-021-00444-2.
- Circulating Extracellular Vesicles Carrying Sphingolipid Cargo for the Diagnosis and Dynamic Risk Profiling of Alcoholic HepatitisSehrawat T, Arab J, Liu M, Amrollahi P, Wan M, Fan J, Nakao Y, Pose E, Navarro‐Corcuera A, Dasgupta D, Liao C, He L, Mauer A, Avitabile E, Ventura‐Cots M, Bataller R, Sanyal A, Chalasani N, Heimbach J, Watt K, Gores G, Gines P, Kamath P, Simonetto D, Hu T, Shah V, Malhi H. Circulating Extracellular Vesicles Carrying Sphingolipid Cargo for the Diagnosis and Dynamic Risk Profiling of Alcoholic Hepatitis. Hepatology 2021, 73: 571-585. PMID: 32246544, PMCID: PMC7541595, DOI: 10.1002/hep.31256.
- Alcohol-Associated Liver DiseaseLiu M, Sehrawat T, Szabo G, Shah V. Alcohol-Associated Liver Disease. 2020, 309-324. DOI: 10.1007/978-3-030-51709-0_20.
- Hyperammonemic Encephalopathy Exacerbated by Parenteral Nutrition in Fibrolamellar Hepatocellular CarcinomaShah P, Cho J, Albitar H, Pajot G, Liu M, Ravi K. Hyperammonemic Encephalopathy Exacerbated by Parenteral Nutrition in Fibrolamellar Hepatocellular Carcinoma. The American Journal Of Medicine 2020, 133: e745-e746. PMID: 32739410, DOI: 10.1016/j.amjmed.2020.06.022.
- Esophageal Varices: Primary Prophylaxis and Prevention and Management of RebleedingLiu M, Hilscher M, Kamath P. Esophageal Varices: Primary Prophylaxis and Prevention and Management of Rebleeding. Current Hepatology Reports 2020, 19: 213-225. DOI: 10.1007/s11901-020-00525-x.
- IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With SteatohepatitisDasgupta D, Nakao Y, Mauer A, Thompson J, Sehrawat T, Liao C, Krishnan A, Lucien F, Guo Q, Liu M, Xue F, Fukushima M, Katsumi T, Bansal A, Pandey M, Maiers J, DeGrado T, Ibrahim S, Revzin A, Pavelko K, Barry M, Kaufman R, Malhi H. IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis. Gastroenterology 2020, 159: 1487-1503.e17. PMID: 32574624, PMCID: PMC7666601, DOI: 10.1053/j.gastro.2020.06.031.
- The knowns and unknowns of treatment for alcoholic hepatitisSehrawat T, Liu M, Shah V. The knowns and unknowns of treatment for alcoholic hepatitis. The Lancet Gastroenterology & Hepatology 2020, 5: 494-506. PMID: 32277902, PMCID: PMC7238289, DOI: 10.1016/s2468-1253(19)30326-7.
- Author Correction: Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigsShaheen M, Joo D, Ross J, Anderson B, Chen H, Huebert R, Li Y, Amiot B, Young A, Zlochiver V, Nelson E, Mounajjed T, Dietz A, Michalak G, Steiner B, Davidow D, Paradise C, van Wijnen A, Shah V, Liu M, Nyberg S. Author Correction: Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs. Nature Biomedical Engineering 2019, 4: 476-476. PMID: 31690827, DOI: 10.1038/s41551-019-0483-3.
- In Reply: Beta-Blocker Use in Refractory AscitesLiu M, Simonetto D. In Reply: Beta-Blocker Use in Refractory Ascites. Mayo Clinic Proceedings 2019, 94: 2364-2365. PMID: 31685161, DOI: 10.1016/j.mayocp.2019.09.009.
- Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigsShaheen M, Joo D, Ross J, Anderson B, Chen H, Huebert R, Li Y, Amiot B, Young A, Zlochiver V, Nelson E, Mounajjed T, Dietz A, Michalak G, Steiner B, Davidow D, Paradise C, van Wijnen A, Shah V, Liu M, Nyberg S. Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs. Nature Biomedical Engineering 2019, 4: 437-445. PMID: 31611679, PMCID: PMC7153989, DOI: 10.1038/s41551-019-0460-x.
- 239 – Mechanotransduction-Induced Glycolysis Epigenetically Regulates a Cxcl1-Dominant Angiocrine Signaling Program in Liver Sinusoidal Endothelial CellsGreuter T, Yaqoob U, Liu M, Huang B, Cao S, Sh V. 239 – Mechanotransduction-Induced Glycolysis Epigenetically Regulates a Cxcl1-Dominant Angiocrine Signaling Program in Liver Sinusoidal Endothelial Cells. Gastroenterology 2019, 156: s-1184. DOI: 10.1016/s0016-5085(19)39932-9.
- New Prospects for Medical Management of Acute Alcoholic HepatitisLiu M, Shah V. New Prospects for Medical Management of Acute Alcoholic Hepatitis. Clinical Liver Disease 2019, 13: 131-135. PMID: 31236260, PMCID: PMC6544414, DOI: 10.1002/cld.792.
- Portal Hypertension and Related Complications: Diagnosis and ManagementSimonetto D, Liu M, Kamath P. Portal Hypertension and Related Complications: Diagnosis and Management. Mayo Clinic Proceedings 2019, 94: 714-726. PMID: 30947834, DOI: 10.1016/j.mayocp.2018.12.020.
- Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal HypertensionHilscher M, Sehrawat T, Arab J, Zeng Z, Gao J, Liu M, Kostallari E, Gao Y, Simonetto D, Yaqoob U, Cao S, Revzin A, Beyder A, Wang R, Kamath P, Kubes P, Shah V. Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension. Gastroenterology 2019, 157: 193-209.e9. PMID: 30872106, PMCID: PMC6581607, DOI: 10.1053/j.gastro.2019.03.013.
- Corrigendum to “Chronic hepatitis B: immune pathogenesis and emerging immunotherapeutics” [Curr. Opin. Pharmacol. 30 (2016) 93–105]Chang K, Liu M. Corrigendum to “Chronic hepatitis B: immune pathogenesis and emerging immunotherapeutics” [Curr. Opin. Pharmacol. 30 (2016) 93–105]. Current Opinion In Pharmacology 2016, 30: 158-159. PMID: 27707534, DOI: 10.1016/j.coph.2016.09.005.
- Chronic hepatitis B: immune pathogenesis and emerging immunotherapeuticsChang K, Liu M. Chronic hepatitis B: immune pathogenesis and emerging immunotherapeutics. Current Opinion In Pharmacology 2016, 30: 93-105. PMID: 27570126, DOI: 10.1016/j.coph.2016.07.013.
- Polyreactivity and Autoreactivity among HIV-1 AntibodiesLiu M, Yang G, Wiehe K, Nicely N, Vandergrift N, Rountree W, Bonsignori M, Alam S, Gao J, Haynes B, Kelsoe G. Polyreactivity and Autoreactivity among HIV-1 Antibodies. Journal Of Virology 2014, 89: 784-798. PMID: 25355869, PMCID: PMC4301171, DOI: 10.1128/jvi.02378-14.
- HIV broadly neutralizing antibodies and immunological tolerance (VAC7P.988)Yang G, Liu M, Wiehe K, Nicely N, Haynes B, Mascola J, Bjorkman P, Kelsoe G. HIV broadly neutralizing antibodies and immunological tolerance (VAC7P.988). The Journal Of Immunology 2014, 192: 141.33-141.33. DOI: 10.4049/jimmunol.192.supp.141.33.
- An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1Bonsignori M, Wiehe K, Grimm S, Lynch R, Yang G, Kozink D, Perrin F, Cooper A, Hwang K, Chen X, Liu M, McKee K, Parks R, Eudailey J, Wang M, Clowse M, Criscione-Schreiber L, Moody M, Ackerman M, Boyd S, Gao F, Kelsoe G, Verkoczy L, Tomaras G, Liao H, Kepler T, Montefiori D, Mascola J, Haynes B. An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1. Journal Of Clinical Investigation 2014, 124: 1835-1843. PMID: 24614107, PMCID: PMC3973118, DOI: 10.1172/jci73441.
- Radiology Education in ChinaWang Y, Liu M, Jin L, Lungren M, Grimm L, Zhang Z, Maxfield C. Radiology Education in China. Journal Of The American College Of Radiology 2013, 10: 213-219. PMID: 23571062, DOI: 10.1016/j.jacr.2012.11.006.