Marcelo Orias, MD, PhD
Associate Professor; Affiliated Faculty, Yale Institute for Global Health
Research & Publications
Biography
News
Coauthors
Selected Publications
- It is strongly recommended to not conduct, fund, or publish research studies that use spot urine samples with estimating equations to assess individuals’ sodium (salt) intake in association with health outcomes: a policy statement of the World Hypertension League, International Society of Hypertension and Resolve to Save LivesCampbell N, Whelton P, Orias M, Cobb L, Jones E, Garg R, Willliams B, Khan N, Chia Y, Jafar T, Ide N. It is strongly recommended to not conduct, fund, or publish research studies that use spot urine samples with estimating equations to assess individuals’ sodium (salt) intake in association with health outcomes: a policy statement of the World Hypertension League, International Society of Hypertension and Resolve to Save Lives. Journal Of Hypertension 2023, 41: 683-686. PMID: 36723484, PMCID: PMC10090307, DOI: 10.1097/hjh.0000000000003385.
- Three Times Weekly Dosing of Daprodustat versus Conventional Epoetin for Treatment of Anemia in Hemodialysis PatientsCoyne DW, Singh AK, Lopes RD, Bailey CK, DiMino TL, Huang C, Connaire J, Rastogi A, Kim SG, Orias M, Shah S, Patel V, Cobitz AR, Wanner C. Three Times Weekly Dosing of Daprodustat versus Conventional Epoetin for Treatment of Anemia in Hemodialysis Patients. Clinical Journal Of The American Society Of Nephrology 2022, 17: 1325-1336. PMID: 35918106, PMCID: PMC9625096, DOI: 10.2215/cjn.00550122.
- Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of HypertensionStergiou G, Brunström M, MacDonald T, Kyriakoulis KG, Bursztyn M, Khan N, Bakris G, Kollias A, Menti A, Muntner P, Orias M, Poulter N, Shimbo D, Williams B, Adeoye AM, Damasceno A, Korostovtseva L, Li Y, Muxfeldt E, Zhang Y, Mancia G, Kreutz R, Tomaszewski M. Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of Hypertension. Journal Of Hypertension 2022, 40: 1847-1858. PMID: 35983870, DOI: 10.1097/hjh.0000000000003240.
- 2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to actionCampbell NRC, Whelton PK, Orias M, Wainford RD, Cappuccio FP, Ide N, Neal B, Cohn J, Cobb LK, Webster J, Trieu K, He FJ, McLean RM, Blanco-Metzler A, Woodward M, Khan N, Kokubo Y, Nederveen L, Arcand J, MacGregor GA, Owolabi MO, Lisheng L, Parati G, Lackland DT, Charchar FJ, Williams B, Tomaszewski M, Romero CA, Champagne B, L’Abbe M, Weber MA, Schlaich MP, Fogo A, Feigin VL, Akinyemi R, Inserra F, Menon B, Simas M, Neves MF, Hristova K, Pullen C, Pandeya S, Ge J, Jalil JE, Wang JG, Wideimsky J, Kreutz R, Wenzel U, Stowasser M, Arango M, Protogerou A, Gkaliagkousi E, Fuchs FD, Patil M, Chan AW, Nemcsik J, Tsuyuki RT, Narasingan SN, Sarrafzadegan N, Ramos ME, Yeo N, Rakugi H, Ramirez AJ, Álvarez G, Berbari A, Kim CI, Ihm SH, Chia YC, Unurjargal T, Park HK, Wahab K, McGuire H, Dashdorj NJ, Ishaq M, Ona DID, Mercado-Asis LB, Prejbisz A, Leenaerts M, Simão C, Pinto F, Almustafa BA, Spaak J, Farsky S, Lovic D, Zhang XH. 2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to action. Journal Of Human Hypertension 2022, 37: 428-437. PMID: 35581323, PMCID: PMC9110933, DOI: 10.1038/s41371-022-00690-0.
- Implementación de la Iniciativa HEARTS en Argentina: primeros resultadosRodriguez G, Rosende A, Prado C, Mariño R, Irazola V, DiPette D, Orias M, Arcila G, Laspiur S. Implementación de la Iniciativa HEARTS en Argentina: primeros resultados. BULL PAN AM HEALTH ORGAN 2022, 46: e181. PMID: 36160765, PMCID: PMC9491484, DOI: 10.26633/rpsp.2022.181.
- Is Isolated Diastolic Hypertension an Important Phenotype?Romero CA, Tabares AH, Orias M. Is Isolated Diastolic Hypertension an Important Phenotype? Current Cardiology Reports 2021, 23: 177. PMID: 34657205, PMCID: PMC8753786, DOI: 10.1007/s11886-021-01609-w.
- Erratum to “Second Consensus on Treatment of Patients Recently Diagnosed with Mild Hypertension and Low Cardiovascular Risk”. [YMCD 45/10 (October 2020) 100653]Morales-Salinas A, Olsen M, Kones R, Kario K, Wang J, Beilin L, Weber M, Yano Y, Burrell L, Orias M, Dzudie A, Lavie C, Ventura H, Sundström J, de Simone G, Coca A, Rumana U, Marrugat J. Erratum to “Second Consensus on Treatment of Patients Recently Diagnosed with Mild Hypertension and Low Cardiovascular Risk”. [YMCD 45/10 (October 2020) 100653]. Current Problems In Cardiology 2021, 46: 100877. PMID: 34148707, DOI: 10.1016/j.cpcardiol.2021.100877.
- Llamado a la acción de San Pablo para la prevención y el control de la hipertensión arterial, 2020Campbell NR, Schutte AE, Varghese CV, Ordunez P, Zhang XH, Khan T, Sharman JE, Whelton PK, Parati G, Weber MA, Orías M, Jaffe MG, Moran AE, Plavnik FL, Ram VS, Brainin M, Owolabi MO, Ramirez AJ, Barbosa E, Bortolotto LA, Lackland DT. Llamado a la acción de San Pablo para la prevención y el control de la hipertensión arterial, 2020. BULL PAN AM HEALTH ORGAN 2021, 45: 1. PMID: 33643404, PMCID: PMC7905751, DOI: 10.26633/rpsp.2021.26.
- Standardized treatment to improve hypertension control in primary health care: The HEARTS in the Americas InitiativeDiPette DJ, Goughnour K, Zuniga E, Skeete J, Ridley E, Angell S, Brettler J, Campbell NRC, Coca A, Connell K, Doon R, Jaffe M, Lopez‐Jaramillo P, Moran A, Orias M, Pineiro DJ, Rosende A, González YV, Ordunez P. Standardized treatment to improve hypertension control in primary health care: The HEARTS in the Americas Initiative. Journal Of Clinical Hypertension 2020, 22: 2285-2295. PMID: 33045133, PMCID: PMC8029673, DOI: 10.1111/jch.14072.
- Global Dialysis Perspective: Argentina.Orias M, Rosa Diez GJ. Global Dialysis Perspective: Argentina. Kidney360 2020, 1: 676-679. PMID: 35372938, PMCID: PMC8815540, DOI: 10.34067/kid.0001222019.
- Second Consensus on Treatment of Patients Recently Diagnosed With Mild Hypertension and Low Cardiovascular RiskMorales-Salinas A, Olsen MH, Kones R, Kario K, Wang J, Beilin L, Weber MA, Yano Y, Burrell L, Orias M, Cameroon DA, Lavie CJ, Ventura H, Sundström J, de Simone G, Coca A, Rumana U, Marrugat J. Second Consensus on Treatment of Patients Recently Diagnosed With Mild Hypertension and Low Cardiovascular Risk. Current Problems In Cardiology 2020, 45: 100653. PMID: 32828558, DOI: 10.1016/j.cpcardiol.2020.100653.
- Hypertension and kidney disease progression.Rigo D, Orias M. Hypertension and kidney disease progression. Clinical Nephrology 2020, 93: 103-107. PMID: 31549630, DOI: 10.5414/cnp92s118.
- SUN-330 RELATIONSHIP BETWEEN THE PRESENCE OF FOAM IN URINE AND THE DIAGNOSIS OF PROTEINURIA IN 24-HOURS URINEPIERINA A, Orias M, Belén B. SUN-330 RELATIONSHIP BETWEEN THE PRESENCE OF FOAM IN URINE AND THE DIAGNOSIS OF PROTEINURIA IN 24-HOURS URINE. Kidney International Reports 2019, 4: s297. DOI: 10.1016/j.ekir.2019.05.739.
- SAT-330 MATERNAL AND NEONATAL SAFETY WITH THE USE OF MAGNESIUM SULFATE IN PREECLAMPSIAGRECCO M, Barrón B, Rigo D, Cook A, Scocco J, Novoa P, Orias M. SAT-330 MATERNAL AND NEONATAL SAFETY WITH THE USE OF MAGNESIUM SULFATE IN PREECLAMPSIA. Kidney International Reports 2019, 4: s146. DOI: 10.1016/j.ekir.2019.05.375.
- 2016 Dietary Salt Fact Sheet and Call to Action: The World Hypertension League, International Society of Hypertension, and the International Council of Cardiovascular Prevention and RehabilitationCampbell NR, Lackland DT, Niebylski ML, Orias M, Redburn KA, Nilsson PM, Zhang X, Burrell L, Horiuchi M, Poulter NR, Prabhakaran D, Ramirez AJ, Schiffrin EL, Schutte AE, Touyz RM, Wang J, Weber MA, Prevention and Rehabilitation I. 2016 Dietary Salt Fact Sheet and Call to Action: The World Hypertension League, International Society of Hypertension, and the International Council of Cardiovascular Prevention and Rehabilitation. Journal Of Clinical Hypertension 2016, 18: 1082-1085. PMID: 27515460, PMCID: PMC8032122, DOI: 10.1111/jch.12894.
- High Blood Pressure 2016: Why Prevention and Control Are Urgent and Important. The World Hypertension League, International Society of Hypertension, World Stroke Organization, International Diabetes Foundation, International Council of Cardiovascular Prevention and Rehabilitation, International Society of NephrologyCampbell NR, Khalsa T, Executive: W, Lackland DT, Niebylski ML, Nilsson PM, Redburn KA, Orias M, Zhang X, Executive: I, Burrell L, Horiuchi M, Poulter NR, Prabhakaran D, Ramirez AJ, Schiffrin EL, Touyz RM, Wang J, Weber MA, Organization W, Federation I, Prevention and Rehabilitation I, Society of Nephrology I. High Blood Pressure 2016: Why Prevention and Control Are Urgent and Important. The World Hypertension League, International Society of Hypertension, World Stroke Organization, International Diabetes Foundation, International Council of Cardiovascular Prevention and Rehabilitation, International Society of Nephrology. Journal Of Clinical Hypertension 2016, 18: 714-717. PMID: 27316336, PMCID: PMC8031792, DOI: 10.1111/jch.12840.
- Clinical practice of ambulatory versus home blood pressure monitoring in hypertensive patients.Paolasso JA, Crespo F, Arias V, Moreyra EA, Volmaro A, Orías M, Moreyra E. Clinical practice of ambulatory versus home blood pressure monitoring in hypertensive patients. Blood Pressure Monitoring 2015, 20: 303-9. PMID: 26110369, DOI: 10.1097/MBP.0000000000000138.
- Resources for Blood Pressure Screening Programs in Low Resource Settings: A Guide From the World Hypertension LeagueMangat BK, Campbell N, Mohan S, Niebylski ML, Khalsa TK, Berbari AE, Cloutier L, Jean-Charles R, Kenerson J, Lemogoum D, Orias M, Veiga E, Zhang XH. Resources for Blood Pressure Screening Programs in Low Resource Settings: A Guide From the World Hypertension League. Journal Of Clinical Hypertension 2015, 17: 418-420. PMID: 25689038, PMCID: PMC8031891, DOI: 10.1111/jch.12499.
- Novel RAAS agonists and antagonists: clinical applications and controversiesRomero CA, Orias M, Weir MR. Novel RAAS agonists and antagonists: clinical applications and controversies. Nature Reviews Endocrinology 2015, 11: 242-252. PMID: 25666495, PMCID: PMC7097622, DOI: 10.1038/nrendo.2015.6.
- Los trastornos Nefrourológicos. Insuficiencia Renal CrónicaBarron Belen, Orias M, 2015. Los trastornos Nefrourológicos. Insuficiencia Renal Crónica. In Greca, Gallo, Parodi, Carlson (Eds.) Medicina Ambulatoria. pp. 773-780, Corpus, Second Edition.
- Novel MoleculesVukelic V, Orias M. Novel Molecules. 2014, 47-55. DOI: 10.1007/978-1-4939-1982-6_5.
- Electron Microscopy Contribution to Diagnosing Transplant Glomerulopathy: A Single-Center ExperienceRigo D, Barrón MB, Martinatto C, Mukdsi J, Orías M, Novoa P. Electron Microscopy Contribution to Diagnosing Transplant Glomerulopathy: A Single-Center Experience. Transplantation Proceedings 2014, 46: 2975-2980. PMID: 25420804, DOI: 10.1016/j.transproceed.2014.07.008.
- A honeycomb glomerular mesangial appearance on ultrastructural examination with minimal IgA deposition in a case of hepatic glomerulosclerosis: a case reportGiotto AP, Barrón B, de Diller AB, Torres A, Orías M, Mukdsi J. A honeycomb glomerular mesangial appearance on ultrastructural examination with minimal IgA deposition in a case of hepatic glomerulosclerosis: a case report. Journal Of Nephropathology 2014, 3: 125-126. PMID: 25374880, PMCID: PMC4219613, DOI: 10.12860/jnp.2014.24.
- Estimated GFR or Albuminuria: Which One Is Really Associated With Resistant Hypertension?Romero CA, Peixoto AJ, Orias M. Estimated GFR or Albuminuria: Which One Is Really Associated With Resistant Hypertension? Seminars In Nephrology 2014, 34: 492-497. PMID: 25416657, DOI: 10.1016/j.semnephrol.2014.08.002.
- Monitoriçåo ambulatorial da pressåo arterial na práctica clínicaCuffaro Paula, Orias M, 2014. Monitoriçåo ambulatorial da pressåo arterial na práctica clínica. In Mion Junior, Nobre y Oigman, (Eds.) Monitoricao Ambulatorial Da Pressao Arterial, pp. 41-47, 5th Edition.
- Hemodynamic circulatory patterns in young patients with predominantly diastolic hypertensionRomero CA, Alfie J, Galarza C, Waisman G, Peixoto AJ, Tabares AH, Orias M. Hemodynamic circulatory patterns in young patients with predominantly diastolic hypertension. International Journal Of Cardiology Cardiovascular Risk And Prevention 2013, 7: 157-162. PMID: 23403215, DOI: 10.1016/j.jash.2013.01.001.
- Does Kidney Disease Cause Hypertension?Peixoto AJ, Orias M, Desir GV. Does Kidney Disease Cause Hypertension? Current Hypertension Reports 2013, 15: 89-94. PMID: 23344662, DOI: 10.1007/s11906-013-0327-6.
- Cardiorenal end points in a trial of aliskiren for type 2 diabetes.Parving HH, Brenner BM, McMurray JJ, de Zeeuw D, Haffner SM, Solomon SD, Chaturvedi N, Persson F, Desai AS, Nicolaides M, Richard A, Xiang Z, Brunel P, Pfeffer MA, ALTITUDE Investigators.. Cardiorenal end points in a trial of aliskiren for type 2 diabetes. N Engl J Med 2012, 367:2204-13.
- A renal variant of Fabry disease: A case with a novel Gal A hemizygote mutation.H Mukdsi J, Gutiérrez S, Barrón B, Novoa P, Fernández S, de Diller AB, I Torres A, Formica RN, Orías M. A renal variant of Fabry disease: A case with a novel Gal A hemizygote mutation. Journal Of Nephropathology 2012, 1: 194-7. PMID: 24475416, PMCID: PMC3886146, DOI: 10.5812/nephropathol.8123.
- 540 INCREASED STROKE VOLUME DETERMINES A HYPERDYNAMIC PATTERN IN PREDOMINANTLY DIASTOLIC HYPERTENSIONRomero C, Tabares A, Alfie J, Waisman G, Orias M. 540 INCREASED STROKE VOLUME DETERMINES A HYPERDYNAMIC PATTERN IN PREDOMINANTLY DIASTOLIC HYPERTENSION. Journal Of Hypertension 2012, 30: e158. DOI: 10.1097/01.hjh.0000420810.05409.93.
- Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentinMarquez D, Ramonda C, Lauxmann JE, Romero CA, Vukelic VL, Martinatto C, Barrón B, Novoa PA, Peixoto AJ, Orías M. Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin. Brazilian Journal Of Nephrology 2012, 34: 148-152. PMID: 22850916, DOI: 10.1590/s0101-28002012000200007.
- Efficacy and safety of early versus late titration of fixed-dose irbesartan/hydrochlorothiazide: ACTUAL study.Girerd X, Rosenbaum D, Aoun J, ACTUAL study Investigators.. Efficacy and safety of early versus late titration of fixed-dose irbesartan/hydrochlorothiazide: ACTUAL study. Blood Press Suppl 2011, 2:22-9.
- Chronotherapy in hypertension: a pill at night makes things right?Orías M, Correa-Rotter R. Chronotherapy in hypertension: a pill at night makes things right? Journal Of The American Society Of Nephrology : JASN 2011, 22: 2152-5. PMID: 22080422, DOI: 10.1681/ASN.2011101012.
- Preemptive Kidney Transplantation: Experience in Two CentersRigo DH, Ziraldo L, Di Monte L, Jimenez MP, Giotto AP, Gutierrez L, Rodriguez I, Orias M, Novoa PA. Preemptive Kidney Transplantation: Experience in Two Centers. Transplantation Proceedings 2011, 43: 3355-3358. PMID: 22099795, DOI: 10.1016/j.transproceed.2011.09.083.
- Can aluminum‐based binders be used safely?Jimenez PM, Douthat W, Orías M. Can aluminum‐based binders be used safely? Seminars In Dialysis 2011, 24: 430-431. PMID: 21801208, DOI: 10.1111/j.1525-139x.2011.00889.x.
- INCREASE STROKE VOLUME DETERMINES A HYPERDYNAMIC PATTERN IN PREDOMINANTLY DIASTOLIC HYPERTENSIONRomero C, Chamale R, Jimenez P, Alfie J, Waisman G, Tabares A, Orias M. INCREASE STROKE VOLUME DETERMINES A HYPERDYNAMIC PATTERN IN PREDOMINANTLY DIASTOLIC HYPERTENSION. Journal Of Hypertension 2011, 29: e526-e527. DOI: 10.1097/00004872-201106001-01596.
- Hypothesis: It Is Time to Reconsider Phenotypes in HypertensionOrias M, Tabares AH, Peixoto AJ. Hypothesis: It Is Time to Reconsider Phenotypes in Hypertension. Journal Of Clinical Hypertension 2010, 12: 350-356. PMID: 20546376, PMCID: PMC8673086, DOI: 10.1111/j.1751-7176.2010.00266.x.
- Emergence of interventional nephrology at the international level.Herrera-Felix JP, Orias M. Emergence of interventional nephrology at the international level. Advances In Chronic Kidney Disease 2009, 16: 309-15. PMID: 19695498, DOI: 10.1053/j.ackd.2009.07.006.
- Is there a role for direct renin inhibitors in chronic kidney disease?Peixoto AJ, Orias M. Is there a role for direct renin inhibitors in chronic kidney disease? Current Opinion In Nephrology & Hypertension 2009, 18: 397-403. PMID: 19584722, DOI: 10.1097/mnh.0b013e32832e3183.
- Aliskiren and the Kidney: Beyond HypertensionTrimarchi H, Orías M. Aliskiren and the Kidney: Beyond Hypertension. Nephrology Research & Reviews 2009, 1: 1-4. DOI: 10.4081/nr.2009.e1.
- Association of ACE genotype and predominantly diastolic hypertension: a preliminary studyJiménez PM, Conde C, Casanegra A, Romero C, Hugo Tabares A, Orías M. Association of ACE genotype and predominantly diastolic hypertension: a preliminary study. Journal Of The Renin-Angiotensin-Aldosterone System 2007, 8: 42-44. PMID: 17487825, DOI: 10.3317/jraas.2007.006.
- Argentine Consensus of HypertensionOrias M. Argentine Consensus of Hypertension. Rebista Aregentina de Cardiologia. 2007; 75 Suppl 3:1-43.
- Renoprotective effect of high periprocedural doses of oral N-acetylcysteine in patients scheduled to undergo a same-day angiography.Balderramo DC, Verdu MB, Ramacciotti CF, Cremona LS, Lemos PA, Orías M, Eduardo M. Renoprotective effect of high periprocedural doses of oral N-acetylcysteine in patients scheduled to undergo a same-day angiography. Revista De La Facultad De Ciencias Me´dicas (Co´rdoba, Argentina) 2004, 61: 13-9. PMID: 16211988.
- P-118: Association of the DD ACE polymorphism and predominantly diastolic hypertensionOrias M, Jimenez P, Conde C, Tabares A. P-118: Association of the DD ACE polymorphism and predominantly diastolic hypertension. American Journal Of Hypertension 2003, 16: 81a-82a. DOI: 10.1016/s0895-7061(03)00284-x.
- Reproducibility of ambulatory blood pressure monitoring in hemodialysis patientsPeixoto A, Santos S, Mendes R, Crowley S, Maldonado R, Orias M, Mansoor G, White W. Reproducibility of ambulatory blood pressure monitoring in hemodialysis patients. American Journal Of Kidney Diseases 2000, 36: 983-990. PMID: 11054355, DOI: 10.1053/ajkd.2000.19100.
- KCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channelsLang R, Lee G, Liu W, Tian S, Rafi H, Orias M, Segal A, Desir G. KCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channels. American Journal Of Physiology. Renal Physiology 2000, 278: f1013-f1021. PMID: 10836990, DOI: 10.1152/ajprenal.2000.278.6.f1013.
- C037: Reproducibility of ambulatory blood pressure in hemodialysis patientsPeixoto A, Santos S, Mendes R, Crowley S, Orias M, Maldonado R, Mansoor G, White W. C037: Reproducibility of ambulatory blood pressure in hemodialysis patients. American Journal Of Hypertension 2000, 13: 223a-223a. DOI: 10.1016/s0895-7061(00)00757-3.
- Extreme Hyperphosphatemia and Acute Renal Failure after a Phosphorus-Containing Bowel RegimenOrias M, Mahnensmith R, Perazella M. Extreme Hyperphosphatemia and Acute Renal Failure after a Phosphorus-Containing Bowel Regimen. American Journal Of Nephrology 1999, 19: 60-63. PMID: 10085452, DOI: 10.1159/000013427.
- Blood pressure regulation by potassium channels.Orias M. Blood pressure regulation by potassium channels. Medicina 1998, 58: 429-32. PMID: 9816709.
- Cloning and localization of a double-pore K channel, KCNK1: exclusive expression in distal nephron segmentsOrias M, Velázquez H, Tung F, Lee G, Desir G. Cloning and localization of a double-pore K channel, KCNK1: exclusive expression in distal nephron segments. American Journal Of Physiology 1997, 273: f663-f666. PMID: 9362344, DOI: 10.1152/ajprenal.1997.273.4.f663.
- Genomic Localization of the Human Gene for KCNA10, a cGMP-Activated K ChannelOrias M, Bray-Ward P, Curran M, Keating M, Desir G. Genomic Localization of the Human Gene for KCNA10, a cGMP-Activated K Channel. Genomics 1997, 42: 33-37. PMID: 9177773, DOI: 10.1006/geno.1997.4712.
- Serum sialic acid, a risk factor for cardiovascular disease, improves following pancreas transplantation.Auersvald LA, Perez RV, Lorber MI, Sturges M, Friedman AL, Bia MJ, Orias M, Wilson J, Azhderian E, Gruber J. Serum sialic acid, a risk factor for cardiovascular disease, improves following pancreas transplantation. Transplantation Proceedings 1995, 27: 3037. PMID: 8539831.