A sparse additive model for high-dimensional interactions with an exposure variableBhatnagar S, Lu T, Lovato A, Olds D, Kobor M, Meaney M, O'Donnell K, Yang A, Greenwood C. A sparse additive model for high-dimensional interactions with an exposure variable Computational Statistics & Data Analysis 2023, 179: 107624. DOI: 10.1016/j.csda.2022.107624.
Impulsivity mediates the relationship between childhood maltreatment and quality of life: Does social support make it different?Gao T, Mei S, Li M, O'Donnell K, Caron J, Meng X. Impulsivity mediates the relationship between childhood maltreatment and quality of life: Does social support make it different? Personality And Individual Differences 2022, 184: 111208. DOI: 10.1016/j.paid.2021.111208.
The PedBE clock accurately estimates DNA methylation age in pediatric buccal cellsMcEwen LM, O'Donnell KJ, McGill MG, Edgar RD, Jones MJ, MacIsaac JL, Lin DTS, Ramadori K, Morin A, Gladish N, Garg E, Unternaehrer E, Pokhvisneva I, Karnani N, Kee MZL, Klengel T, Adler NE, Barr RG, Letourneau N, Giesbrecht GF, Reynolds JN, Czamara D, Armstrong JM, Essex MJ, de Weerth C, Beijers R, Tollenaar MS, Bradley B, Jovanovic T, Ressler KJ, Steiner M, Entringer S, Wadhwa PD, Buss C, Bush NR, Binder EB, Boyce WT, Meaney MJ, Horvath S, Kobor MS. The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 117: 23329-23335. PMID: 31611402, PMCID: PMC7519312, DOI: 10.1073/pnas.1820843116.
Positive life events during pregnancy and cellular aging in infantsLazarides C, Epel E, Lin J, Blackburn E, Pokhvisneva I, Oldach M, Meaney M, O’Donnell K, Kobor M, MacIsaac J, Lin D, Buss C, Simhan H, Wadhwa P, Entringer S. Positive life events during pregnancy and cellular aging in infants Psychoneuroendocrinology 2019, 107: 34. DOI: 10.1016/j.psyneuen.2019.07.095.
Association between a biologically-informed polygenic score based on the mesocorticolimbic insulin receptor gene network and at-risk individual characteristics for mental health: A replication in a population-based longitudinal cohortOuellet-Morin I, Silveira P, Paquin S, Langevin S, Morneau-Vaillancourt G, O’Donnell K, Boivin M. Association between a biologically-informed polygenic score based on the mesocorticolimbic insulin receptor gene network and at-risk individual characteristics for mental health: A replication in a population-based longitudinal cohort Psychoneuroendocrinology 2019, 107: 80. DOI: 10.1016/j.psyneuen.2019.07.230.
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-bornsCzamara D, Eraslan G, Page CM, Lahti J, Lahti-Pulkkinen M, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Nystad W, Håberg SE, London SJ, O’Donnell K, Garg E, Meaney MJ, Entringer S, Wadhwa PD, Buss C, Jones MJ, Lin DTS, MacIsaac JL, Kobor MS, Koen N, Zar HJ, Koenen KC, Dalvie S, Stein DJ, Kondofersky I, Müller NS, Theis FJ, Räikkönen K, Binder E. Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns Nature Communications 2019, 10: 2548. PMID: 31186427, PMCID: PMC6559955, DOI: 10.1038/s41467-019-10461-0.
F42. Childhood Internalizing Symptoms and Epigenetic AgingTollenaar M, Beijers R, Garg E, Nguyen T, Lin D, MacIsaac J, Shalev I, Kobor M, Meaney M, O'Donnell K, de Weerth C. F42. Childhood Internalizing Symptoms and Epigenetic Aging Biological Psychiatry 2019, 85: s228. DOI: 10.1016/j.biopsych.2019.03.579.
OXTR brain tissue expression quantitative locus rs237895 moderates the association between maternal childhood maltreatment and non-optimal maternal behavior with implications for offspring socio-emotional development and attachment securityToepfer P, O’Donnell K, Entringer S, Heim C, Lin D, MacIsaac J, Kobor M, Meaney M, Provencal N, Binder E, Wadhwa P, Buss C. OXTR brain tissue expression quantitative locus rs237895 moderates the association between maternal childhood maltreatment and non-optimal maternal behavior with implications for offspring socio-emotional development and attachment security Psychoneuroendocrinology 2019, 100: s48. DOI: 10.1016/j.psyneuen.2018.12.167.
SU9 IDENTIFICATION OF GENES IN CHILD GENETIC RISK FOR ATTENTION DEFICIT/HYPERACTIVITY DISORDER THAT INTERACT WITH MATERNAL DEPRESSIVE SYMPTOMS IN PREDICTION OF INTERNALIZING PROBLEMSChen L, Bouvette-Turcot A, Garg E, Nguyen T, Silveira P, Diorio J, Kobor M, O'Donnell K, Meaney M. SU9 IDENTIFICATION OF GENES IN CHILD GENETIC RISK FOR ATTENTION DEFICIT/HYPERACTIVITY DISORDER THAT INTERACT WITH MATERNAL DEPRESSIVE SYMPTOMS IN PREDICTION OF INTERNALIZING PROBLEMS European Neuropsychopharmacology 2019, 29: s891. DOI: 10.1016/j.euroneuro.2017.08.198.
The early care environment and DNA methylome variation in childhoodGarg E, Chen L, Nguyen TTT, Pokhvisneva I, Chen LM, Unternaehrer E, MacIsaac JL, McEwen LM, Mah SM, Gaudreau H, Levitan R, Moss E, Sokolowski MB, Kennedy JL, Steiner MS, Meaney MJ, Holbrook JD, Silveira PP, Karnani N, Kobor MS, O'Donnell KJ. The early care environment and DNA methylome variation in childhood Development And Psychopathology 2018, 30: 891-903. PMID: 30068421, DOI: 10.1017/s0954579418000627.
Epigenetics and Early Life Adversity: Current Evidence and Considerations for Epigenetic Studies in the Context of Child MaltreatmentBouvette-Turcot A, Meaney M, O’Donnell K. Epigenetics and Early Life Adversity: Current Evidence and Considerations for Epigenetic Studies in the Context of Child Maltreatment 2018, 89-119. DOI: 10.1007/978-3-319-72589-5_7.
Interaction between maternal cortisol in pregnancy and infant FKBP5 genotype on newborn hippocampal volume and infant stress reactivity at 12 monthsMoog N, Entringer S, Styner M, O’Donnell K, Gilmore J, Meaney M, Binder E, Heim C, Wadhwa P, Buss C. Interaction between maternal cortisol in pregnancy and infant FKBP5 genotype on newborn hippocampal volume and infant stress reactivity at 12 months Psychoneuroendocrinology 2017, 83: 26. DOI: 10.1016/j.psyneuen.2017.07.308.
New Insights into Prenatal Stress: Immediate- and Long-Term Effects on the Fetus and Their TimingO’Donnell K, Reissland N, Glover V. New Insights into Prenatal Stress: Immediate- and Long-Term Effects on the Fetus and Their Timing 2017, 75-85. DOI: 10.1007/978-3-319-53232-5_8.
551 Maternal History of Early Adversity and Offspring Temperament: Investigating Rearing Environmental and Genetic ContributionsBouvette-Turcot A, Unternäehrer E, O׳Donnell K, Chen L, Gaudreau H, Silveira P, Meaney M. 551 Maternal History of Early Adversity and Offspring Temperament: Investigating Rearing Environmental and Genetic Contributions Biological Psychiatry 2017, 81: s223. DOI: 10.1016/j.biopsych.2017.02.1159.
Intergenerational transmission of well being–genetic and epigenetic mechanismsUnternaehrer E, Greenlaw K, Dass S, Chen L, Bouvette-Turcot A, Cost K, O’Donnell K, Gaudreau H, McEwen L, MacIsaac J, Kobor M, Fleming A, Atkinson L, Lydon J, Steiner M, Ciampi A, Greenwood C, Meaney M. Intergenerational transmission of well being–genetic and epigenetic mechanisms European Psychiatry 2017, 41: s29-s30. DOI: 10.1016/j.eurpsy.2017.01.146.
Inter-individual differences in the effects of maternal prenatal anxiety on child neurodevelopment: Implications for personalized medicine in perinatal mental healthO’Donnell K, Glover V, Edgar R, O’Connor T. Inter-individual differences in the effects of maternal prenatal anxiety on child neurodevelopment: Implications for personalized medicine in perinatal mental health Psychoneuroendocrinology 2016, 71: 6. DOI: 10.1016/j.psyneuen.2016.07.024.
Chapter 7 Maternal Prenatal Stress and the Developmental Origins of Mental Health The Role of EpigeneticsO’Donnell K, Glover V. Chapter 7 Maternal Prenatal Stress and the Developmental Origins of Mental Health The Role of Epigenetics 2016, 103-126. DOI: 10.1016/b978-0-12-801383-0.00007-4.
Maternal early life adversities and the offspring's epigenome: A M.A.V.A.N. projectUnternaehrer E, O’Donnell K, Bouvette-Turcot A, Gaudreau H, Cost K, Fleming A, Steiner M, MacIsaac J, Mah S, McEwen L, Kobor M, Chen L, Pan H, Hui W, Holbrook J, Meaney M, MAVAN S. Maternal early life adversities and the offspring's epigenome: A M.A.V.A.N. project Psychoneuroendocrinology 2015, 61: 32. DOI: 10.1016/j.psyneuen.2015.07.477.
Prenatal maternal depression and aberrant placental imprintingJanssen A, Capron L, O’Donnell K, Tunster S, Heazell A, Ramchandani P, Glover V, John R. Prenatal maternal depression and aberrant placental imprinting Psychoneuroendocrinology 2015, 61: 4. DOI: 10.1016/j.psyneuen.2015.07.396.
Prenatal anxiety and depression, fetal programming and placental functionGlover V, O’Donnell K, O’Connor T, Ramchandani P, Capron L. Prenatal anxiety and depression, fetal programming and placental function Psychoneuroendocrinology 2015, 61: 3-4. DOI: 10.1016/j.psyneuen.2015.07.395.
Epigenetics and the developmental origins of vulnerability for mental disordersMeaney M, O'Donnell K, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Epigenetics and the developmental origins of vulnerability for mental disorders 2015, 317-329. DOI: 10.1002/9781118381953.ch25.
Down regulation of placental PEG3 infers placental programming of maternal prenatal depressionJensen A, O'Donnell K, Tunster S, John R, Glover V. Down regulation of placental PEG3 infers placental programming of maternal prenatal depression Placenta 2014, 35: a35-a36. DOI: 10.1016/j.placenta.2014.06.118.
P02-503 - Diurnal pattern of cortisol and amylase output in postnatal depressionKammerer M, Taylor A, Khalife N, O’Donnell K, Marks M, Glover V. P02-503 - Diurnal pattern of cortisol and amylase output in postnatal depression European Psychiatry 2011, 26: 1099. DOI: 10.1016/s0924-9338(11)72804-8.
Maternal stress, anxiety, and depression during pregnancy: effects on the fetus and the childGlover V, O’Donnell K, O’Connor T. Maternal stress, anxiety, and depression during pregnancy: effects on the fetus and the child 2010, 266-270. DOI: 10.1093/med/9780199214365.003.0029.
New Insights into Prenatal Stress: Immediate and Long-Term Effects on the Fetus and Their TimingO’Donnell K, Glover V. New Insights into Prenatal Stress: Immediate and Long-Term Effects on the Fetus and Their Timing 2008, 57-64. DOI: 10.1007/978-88-470-0732-1_8.