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John Geibel

DSc, MD, AGAF, MS, FRS

Professor Emeritus of Surgery (Gastrointestinal); Vice Chair, Surgery; Director, Surgical Research; American Gastroenterological Association Fellow; Fellow of the Royal Society of Medicine

Research & Publications
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Research Summary

Our primary focus is on real time monitoring of ion transport mechanisms in epithelia, using high-resolution microscopy. One of the crucial problems facing all epithelial cells is the control of the intracellular milieu. In an effort to maintain ionic homeostasis, epithelial cells have devised a variety of ion channels, transport proteins, and carriers to regulate and maintain the intracellular ionic concentrations. To further understand how ions are transported in epithelial cells, we have developed a variety of optical techniques to continuously monitor intracellular ionic concentrations in real time. Using high-resolution video or confocal microscopy we are presently able to monitor intracellular Ca2+, Na+, K+, Cl-, pH, and membrane potential. We are currently investigating various aspects of renal tubule and gastric tissue ion transport in intact renal tubules and gastric glands. We also are characterizing the secretory and reabsorptive properties of the colonic crypt, with a special focus on diarrheal disease.

Specialized Terms: Gastric Acid Secretion; Colonic Fluid Transport; Renal Physiology; Intracellular Ion Activity Measurements; Calcium Sensing Receptor; Diarrheal disease; electrophysiology; CFTR; AMPKinase volume regulation

Extensive Research Description

We are focused on 3 main areas; gastric ion transport in health and disease, intestinal ion transport in health and disease, and 3DBioprinting. For gastric ion transport we are focusing on means to modulate acid secretion and reverse erosion. We use a combination of natural products and biochemical modifications to treat acid disease at the cellular level. For studies of intestinal ion transport, we are focusing on how the calcium sensing receptor(CaSR) can modulate fluid transport during toxin induced diarrhea. We are also looking at nanoparticle therapies for Ulcerative Colitis. In addition we are investigating means to prevent ischemic injury by activating ionic pathways using the AMPKinase. Finally we are trying to prevent IBD/IBS associated epithelial injury in the gut by CaSR activation using nutraceuticals . For the 3DBioprinting area we are developing replacement conduits that can be used for the aorta, the inferior vena cava, and also as small and large intestine repair tool. Along with this research we are now examining the potential for intestinal elongation using a 3D printed replacement.

Coauthors

Research Interests

Diarrhea; Electrophysiology; Gastric Acid; Gastroenterology; Gastrointestinal Agents; Physiology; Bioprinting; Chemicals and Drugs

Research Image

Isolated Human Gastric Gland

Isolated gastric gland loaded with the pH sensitive dye BCECF and a lysosomal tracker on a Zeiss Spinning Disk confocal. Image shows 3-D reconstruction of the gland in real time.

Selected Publications

3D Bioprinting Using Hydrogels: Cell Inks and Tissue Engineering ApplicationsDell A, Wagner G, Own J, Geibel J. 3D Bioprinting Using Hydrogels: Cell Inks and Tissue Engineering Applications Pharmaceutics 2022, 14: 2596. PMID: 36559090, PMCID: PMC9784738, DOI: 10.3390/pharmaceutics14122596.
L-ARGININE PREVENTS ISCHEMIC INJURY IN EXPLANTED RAT INTESTINAL REGIONS IN AN EX VIVO PERFUSION MODELFinotti M, Barahona M, Maina R, Lysyy T, Agarwal R, Schmitt P, Caturegli G, Di Renzo C, Anselmo A, Mulligan D, Geibel J, D'Amico F. L-ARGININE PREVENTS ISCHEMIC INJURY IN EXPLANTED RAT INTESTINAL REGIONS IN AN EX VIVO PERFUSION MODEL Transplantation Reports 2022, 7: 100096. DOI: 10.1016/j.tpr.2022.100096.
Colonic Fluid and Electrolyte Transport 2022: An UpdateNegussie AB, Dell AC, Davis BA, Geibel JP. Colonic Fluid and Electrolyte Transport 2022: An Update Cells 2022, 11: 1712. PMID: 35626748, PMCID: PMC9139964, DOI: 10.3390/cells11101712.
Gastric secretionsGeibel J. Gastric secretions 2022, 313-333. DOI: 10.1002/9781119600206.ch17.
3D Bioprinting of Vascularized Tissues for in vitro and in vivo ApplicationsChen EP, Toksoy Z, Davis BA, Geibel JP. 3D Bioprinting of Vascularized Tissues for in vitro and in vivo Applications Frontiers In Bioengineering And Biotechnology 2021, 9: 664188. PMID: 34055761, PMCID: PMC8158943, DOI: 10.3389/fbioe.2021.664188.
Bile Microbiota in Liver Transplantation: Proof of Concept Using Gene Amplification in a Heterogeneous Clinical ScenarioD'Amico F, Bertacco A, Finotti M, Di Renzo C, Rodriguez-Davalos MI, Gondolesi GE, Cillo U, Mulligan D, Geibel J. Bile Microbiota in Liver Transplantation: Proof of Concept Using Gene Amplification in a Heterogeneous Clinical Scenario Frontiers In Surgery 2021, 8: 621525. PMID: 33796547, PMCID: PMC8009296, DOI: 10.3389/fsurg.2021.621525.
Hydrogel‐based 3D bioprints repair rat small intestine injuries and integrate into native intestinal tissueMaina RM, Barahona MJ, Geibel P, Lysyy T, Finotti M, Isaji T, Wengerter B, Mentone S, Dardik A, Geibel JP. Hydrogel‐based 3D bioprints repair rat small intestine injuries and integrate into native intestinal tissue Journal Of Tissue Engineering And Regenerative Medicine 2020, 15: 129-138. PMID: 33197151, DOI: 10.1002/term.3157.
Penicillin G Induces H+, K+-ATPase via a Nitric Oxide-Dependent Mechanism in the Rat Colonic CryptBaratta VM, Norz V, Barahona MJ, Gisinger TM, Mulligan D, Geibel JP. Penicillin G Induces H+, K+-ATPase via a Nitric Oxide-Dependent Mechanism in the Rat Colonic Crypt Cellular Physiology And Biochemistry 2020, 54: 1132-1142. PMID: 33175479, PMCID: PMC8095381, DOI: 10.33594/000000305.
Human Small Intestine Transplantation: Segmental Susceptibility to Ischemia Using Different Preservation Solutions and ConditionsLysyy T, Finotti M, Maina RM, Morotti R, Munoz-Abraham AS, Bertacco A, Ibarra C, Barahona M, Agarwal R, D'Amico F, Rodriguez-Davalos MI, Mulligan D, Geibel J. Human Small Intestine Transplantation: Segmental Susceptibility to Ischemia Using Different Preservation Solutions and Conditions Transplantation Proceedings 2020, 52: 2934-2940. PMID: 32768284, DOI: 10.1016/j.transproceed.2020.06.031.
In Pursuit of the Parietal Cell – An Evolution of Scientific Methodology and TechniquesBaratta V, Own J, Di Renzo C, Ollodart J, Geibel JP, Barahona M. In Pursuit of the Parietal Cell – An Evolution of Scientific Methodology and Techniques Frontiers In Physiology 2019, 10: 1497. PMID: 31920702, PMCID: PMC6920182, DOI: 10.3389/fphys.2019.01497.
Induction of Secretagogue Independent Gastric Acid Secretion via a Novel Aspirin-Activated PathwayKitay AM, Ferstl FS, Link A, Geibel JP. Induction of Secretagogue Independent Gastric Acid Secretion via a Novel Aspirin-Activated Pathway Frontiers In Physiology 2019, 10: 1264. PMID: 31649553, PMCID: PMC6795678, DOI: 10.3389/fphys.2019.01264.
The calcium‐sensing receptor: A novel target for treatment and prophylaxis of neratinib‐induced diarrheaLysyy T, Lalani AS, Olek EA, Diala I, Geibel JP. The calcium‐sensing receptor: A novel target for treatment and prophylaxis of neratinib‐induced diarrhea Pharmacology Research & Perspectives 2019, 7: e00521. PMID: 31523434, PMCID: PMC6743423, DOI: 10.1002/prp2.521.
Activation of the Calcium Sensing Receptor Decreases Secretagogue-Induced Fluid Secretion in the Rat Small IntestineBarahona MJ, Maina RM, Lysyy T, Finotti M, Caturegli G, Baratta V, D’Amico F, Mulligan D, Geibel JP. Activation of the Calcium Sensing Receptor Decreases Secretagogue-Induced Fluid Secretion in the Rat Small Intestine Frontiers In Physiology 2019, 10: 439. PMID: 31130866, PMCID: PMC6509940, DOI: 10.3389/fphys.2019.00439.
Mo1102 – Aspirin and Ischemia in the Murine Distal ColonBaratta V, Barahona M, Mulligan D, Geibel J. Mo1102 – Aspirin and Ischemia in the Murine Distal Colon Gastroenterology 2019, 156: s-708. DOI: 10.1016/s0016-5085(19)38700-1.
Sa1745 – Glacial Acetic Acid-Induced Ulcerative Colitis Lesions Improve After Oral Calcium Nanoparticle Therapy in a Rat ModelBarahona M, Baratta V, Mulligan D, Geibel J. Sa1745 – Glacial Acetic Acid-Induced Ulcerative Colitis Lesions Improve After Oral Calcium Nanoparticle Therapy in a Rat Model Gastroenterology 2019, 156: s-384. DOI: 10.1016/s0016-5085(19)37812-6.
Sa1746 – Oral Calcium Nanoparticle Therapy Aids in the Recovery from Dss-Induced Ulcerative Colitis in the Rat ModelBaratta V, Barahona M, Mulligan D, Geibel J. Sa1746 – Oral Calcium Nanoparticle Therapy Aids in the Recovery from Dss-Induced Ulcerative Colitis in the Rat Model Gastroenterology 2019, 156: s-384-s-385. DOI: 10.1016/s0016-5085(19)37813-8.
Design and implementation of novel nutraceuticals and derivatives for treating intestinal disordersBarahona MJ, Baratta V, Ollodart J, Mulligan D, Geibel JP. Design and implementation of novel nutraceuticals and derivatives for treating intestinal disorders Future Medicinal Chemistry 2019, 11: 847-855. PMID: 30994367, PMCID: PMC8008207, DOI: 10.4155/fmc-2018-0313.
Activation of the Calcium Sensing Receptor (casr) Prevents Secretagogue-Induced Diarrhea in the Rat Small IntestineFinotti M, Lysyy T, Caturegli G, Barahona M, Maina R, D'Amico F, Mulligan D, Geibel J. Activation of the Calcium Sensing Receptor (casr) Prevents Secretagogue-Induced Diarrhea in the Rat Small Intestine Transplantation 2018, 102: s669. DOI: 10.1097/01.tp.0000543607.00911.f4.
Prevention of Ischemic Injury in Colon and Small Intestine in an Ex Vivo Perfusion Animal ModelFinotti M, Lysyy T, Barahona M, Maina R, Caturegli G, D'Amico F, Mulligan D, Geibel J. Prevention of Ischemic Injury in Colon and Small Intestine in an Ex Vivo Perfusion Animal Model Transplantation 2018, 102: s709. DOI: 10.1097/01.tp.0000543675.85457.d2.
Generating vascular conduits: from tissue engineering to three-dimensional bioprintingMaina RM, Barahona MJ, Finotti M, Lysyy T, Geibel P, D’Amico F, Mulligan D, Geibel JP. Generating vascular conduits: from tissue engineering to three-dimensional bioprinting Innovative Surgical Sciences 2018, 3: 203-213. PMID: 31579784, PMCID: PMC6604577, DOI: 10.1515/iss-2018-0016.
Sa1180 - Activation of the Calcium Sensing Receptor (Casr) Leads to Enhanced Fluid and Electrolyte Absorption in the Rat Small IntestineLysyy T, Caturegli G, Finotti M, Maina R, Barahona M, D'Amico F, Mulligan D, Geibel J. Sa1180 - Activation of the Calcium Sensing Receptor (Casr) Leads to Enhanced Fluid and Electrolyte Absorption in the Rat Small Intestine Gastroenterology 2018, 154: s-269-s-270. DOI: 10.1016/s0016-5085(18)31261-7.
Sa1181 - Zinc Acetate Inhibits Metformin-Stimulated H+-Atpasedependent Gastric Acid SecretionGeibel J, Schneebacher M, Stroehl Y, Barahona M. Sa1181 - Zinc Acetate Inhibits Metformin-Stimulated H+-Atpasedependent Gastric Acid Secretion Gastroenterology 2018, 154: s-270. DOI: 10.1016/s0016-5085(18)31262-9.
Sa1178 - Activation of the Vacuolar H+-Atpase via Casr Activation in the RatStroehl Y, Finotti M, Geibel J, Barahona M. Sa1178 - Activation of the Vacuolar H+-Atpase via Casr Activation in the Rat Gastroenterology 2018, 154: s-269. DOI: 10.1016/s0016-5085(18)31259-9.
Tu1257 - Three-Dimensional Printed Biopatches are Viable Conduits for Repair of small Intestinal Injuries in a Rat ModelMaina R, Geibel P, Lysyy T, Finotti M, Wengerter B, Barahona M, Caturegli G, Geibel J. Tu1257 - Three-Dimensional Printed Biopatches are Viable Conduits for Repair of small Intestinal Injuries in a Rat Model Gastroenterology 2018, 154: s-917. DOI: 10.1016/s0016-5085(18)33083-x.
Modulations in extracellular calcium lead to H+-ATPase-dependent acid secretion: a clarification of PPI failureKitay AM, Schneebacher MT, Schmitt A, Heschl K, Kopic S, Alfadda T, Alsaihati A, Link A, Geibel J. Modulations in extracellular calcium lead to H+-ATPase-dependent acid secretion: a clarification of PPI failure AJP Gastrointestinal And Liver Physiology 2018, 315: g36-g42. PMID: 29517927, DOI: 10.1152/ajpgi.00132.2017.
Modulation of Intestinal Microbiome Prevents Intestinal Ischemic InjuryBertacco A, Dehner CA, Caturegli G, D'Amico F, Morotti R, Rodriguez MI, Mulligan DC, Kriegel MA, Geibel JP. Modulation of Intestinal Microbiome Prevents Intestinal Ischemic Injury Frontiers In Physiology 2017, 8: 1064. PMID: 29311987, PMCID: PMC5742259, DOI: 10.3389/fphys.2017.01064.
Activation of Secretagogue Independent Gastric Acid Secretion via Endothelial Nitric Oxide Synthase Stimulation in RatsKitay AM, Link A, Geibel JP. Activation of Secretagogue Independent Gastric Acid Secretion via Endothelial Nitric Oxide Synthase Stimulation in Rats Cellular Physiology And Biochemistry 2017, 44: 1606-1615. PMID: 29212068, DOI: 10.1159/000485755.
Acute Effects of Vitamin C Exposure On Colonic Crypts: Direct Modulation of pH RegulationAldajani MM, Vanicek CN, Alhazzaa N, Lysyy T, Agarwal R, Geibel JP. Acute Effects of Vitamin C Exposure On Colonic Crypts: Direct Modulation of pH Regulation Cellular Physiology And Biochemistry 2017, 44: 377-387. PMID: 29132138, DOI: 10.1159/000484914.
Stomach and BoneKitay AM, Geibel JP. Stomach and Bone 2017, 1033: 97-131. PMID: 29101653, DOI: 10.1007/978-3-319-66653-2_6.
Sa1982 Elevated no Production is Protective Against Small Intestine Ischemic InjuryIbarra C, Caturegli G, Abraham A, Rodriguez-Davalos M, Mulligan D, Geibel J. Sa1982 Elevated no Production is Protective Against Small Intestine Ischemic Injury Gastroenterology 2017, 152: s415-s416. DOI: 10.1016/s0016-5085(17)31617-7.
Tu1595 Acute Exposure to Vitamin C Activates Na+-H+ Exchanger 4(NHE4) in Colonic CryptsAldajani M, Alhazzaa N, Geibel J. Tu1595 Acute Exposure to Vitamin C Activates Na+-H+ Exchanger 4(NHE4) in Colonic Crypts Gastroenterology 2017, 152: s912. DOI: 10.1016/s0016-5085(17)33114-1.
Tu1597 Zinc Acts as a Potent Inhibitor of Aspirin Induced Gastric Acid Secretion in Rat Gastric GlandsFerstl F, Kitay A, Geibel J. Tu1597 Zinc Acts as a Potent Inhibitor of Aspirin Induced Gastric Acid Secretion in Rat Gastric Glands Gastroenterology 2017, 152: s912. DOI: 10.1016/s0016-5085(17)33116-5.
3D Bioprinting in TransplantationMunoz-Abraham A, Ibarra C, Agarwal R, Geibel J, Mulligan D. 3D Bioprinting in Transplantation 2017, 261-276. DOI: 10.1007/978-3-319-62142-5_11.
Chapter 2 Molecular Aspects of the Calcium-Sensing Receptor and Calcium HomeostasisAlkukhun A, Munoz-Abraham A, Judeeba S, Geibel J. Chapter 2 Molecular Aspects of the Calcium-Sensing Receptor and Calcium Homeostasis 2017, 15-26. DOI: 10.1016/b978-0-12-802168-2.00002-6.
Use of Fluorescein Isothiocyanate-Inulin as a Marker for Intestinal Ischemic InjuryAlKukhun A, Caturegli G, Munoz-Abraham AS, Judeeba S, Patron-Lozano R, Morotti R, Rodriguez-Davalos MI, Geibel JP. Use of Fluorescein Isothiocyanate-Inulin as a Marker for Intestinal Ischemic Injury Journal Of The American College Of Surgeons 2016, 224: 1066-1073. PMID: 28017811, DOI: 10.1016/j.jamcollsurg.2016.12.016.
Secretagogue-dependent and -independent transport of zinc hydration forms in rat parietal cellsFerstl FS, Kitay AM, Trattnig RM, Alsaihati A, Geibel JP. Secretagogue-dependent and -independent transport of zinc hydration forms in rat parietal cells Pflügers Archiv - European Journal Of Physiology 2016, 468: 1877-1883. PMID: 27757581, DOI: 10.1007/s00424-016-1889-3.
Is Normothermic Perfusion a Feasible Option for Intestinal Preservation? Experience with a Porcine ModelBertacco A, AlKukhun A, Kitay A, Aldajani M, D'Amico F, Rodriguez-Davalos M, Mulligan D, Geibel J. Is Normothermic Perfusion a Feasible Option for Intestinal Preservation? Experience with a Porcine Model Journal Of The American College Of Surgeons 2016, 223: e50-e51. DOI: 10.1016/j.jamcollsurg.2016.08.147.
Use of FITC-Inulin As a Real-Time Marker For Intestinal Graft ViabilityAlKukhun A, Bertacco A, Abraham A, Caturegli G, D'Amico F, Rodriguez-Davalos M, Mulligan D, Geibel J. Use of FITC-Inulin As a Real-Time Marker For Intestinal Graft Viability Journal Of The American College Of Surgeons 2016, 223: e193. DOI: 10.1016/j.jamcollsurg.2016.08.489.
Three-dimensional Printing in the IntestineWengerter BC, Emre G, Park JY, Geibel J. Three-dimensional Printing in the Intestine Clinical Gastroenterology And Hepatology 2016, 14: 1081-1085. PMID: 27189913, DOI: 10.1016/j.cgh.2016.05.008.
Su1913 Stimulation of the Intestinal Microbiome By Lactate Perfusion Prevents Ischemic InjuryGeibel J, Dehner C, Bertacco A, Caturegli G, Kriegel M, Rodriguez-Davalos M, D'Amico F. Su1913 Stimulation of the Intestinal Microbiome By Lactate Perfusion Prevents Ischemic Injury Gastroenterology 2016, 150: s586-s587. DOI: 10.1016/s0016-5085(16)32012-1.
Tu1415 Renalase Protects Against Intestinal Ischemic InjuryAlkukhun A, Wang Y, Guo X, Dehner C, Desir G, Geibel J. Tu1415 Renalase Protects Against Intestinal Ischemic Injury Gastroenterology 2016, 150: s899. DOI: 10.1016/s0016-5085(16)33039-6.
3D Printing of Organs for Transplantation: Where Are We and Where Are We Heading?Munoz-Abraham A, Rodriguez-Davalos M, Bertacco A, Wengerter B, Geibel J, Mulligan D. 3D Printing of Organs for Transplantation: Where Are We and Where Are We Heading? Current Transplantation Reports 2016, 3: 93-99. DOI: 10.1007/s40472-016-0089-6.
Extracorporeal Hypothermic Perfusion Device for Intestinal Graft Preservation to Decrease Ischemic Injury During TransportationMuñoz-Abraham AS, Patrón-Lozano R, Narayan RR, Judeeba SS, Alkukhun A, Alfadda TI, Belter JT, Mulligan DC, Morotti R, Zinter JP, Geibel JP, Rodríguez-Dávalos MI. Extracorporeal Hypothermic Perfusion Device for Intestinal Graft Preservation to Decrease Ischemic Injury During Transportation Journal Of Gastrointestinal Surgery 2015, 20: 313-321. PMID: 26487331, DOI: 10.1007/s11605-015-2986-x.
Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epitheliumMcNeer NA, Anandalingam K, Fields RJ, Caputo C, Kopic S, Gupta A, Quijano E, Polikoff L, Kong Y, Bahal R, Geibel JP, Glazer PM, Saltzman WM, Egan ME. Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium Nature Communications 2015, 6: 6952. PMID: 25914116, PMCID: PMC4480796, DOI: 10.1038/ncomms7952.
A new method to measure intestinal secretion using fluorescein isothiocyanate-inulin in small bowel of ratsMunoz-Abraham AS, Judeeba S, Alkukhun A, Alfadda T, Patron-Lozano R, Rodriguez-Davalos MI, Geibel JP. A new method to measure intestinal secretion using fluorescein isothiocyanate-inulin in small bowel of rats Journal Of Surgical Research 2015, 197: 225-230. PMID: 25976849, DOI: 10.1016/j.jss.2015.02.049.
974 Extracorporeal Hypothermic Perfusion Device for Human Intestine Preservation to Decrease Ischemic Injury During Graft TransportationMunoz-Abraham A, Patron-Lozano R, Alfadda T, Judeeba S, Alkukhun A, Narayan R, Chauhan Y, Belter J, Morotti R, Zinter J, Rodriguez-Davalos M, Geibel J. 974 Extracorporeal Hypothermic Perfusion Device for Human Intestine Preservation to Decrease Ischemic Injury During Graft Transportation Gastroenterology 2015, 148: s-1127. DOI: 10.1016/s0016-5085(15)33838-5.
Tu1406 Effect of Induced Ischemia on Intestinal Fluid Secretion: A Novel ApproachAlkukhun A, Judeeba S, Munoz-Abraham A, Patron-Lozano R, Rodriguez-Davalos M, Geibel J. Tu1406 Effect of Induced Ischemia on Intestinal Fluid Secretion: A Novel Approach Gastroenterology 2015, 148: s-881. DOI: 10.1016/s0016-5085(15)32993-0.
Tu1899 Gastric Acid Secretion via the H+-ATPase Is Modulated by the Calcium-Sensing ReceptorAlfadda T, Alsaihati A, Schmitt A, Bloecker K, Kopic S, Geibel J. Tu1899 Gastric Acid Secretion via the H+-ATPase Is Modulated by the Calcium-Sensing Receptor Gastroenterology 2015, 148: s-931. DOI: 10.1016/s0016-5085(15)33169-3.
The Putative Role of the Non-Gastric H+/K+-ATPase ATP12A (ATP1AL1) as Anti-Apoptotic Ion Transporter: Effect of the H+/K+ ATPase Inhibitor SCH28080 on Butyrate-Stimulated Myelomonocytic HL-60 CellsJakab M, Hofer S, Ravasio A, Huber F, Schmidt S, Hitzl W, Geibel JP, Fürst J, Ritter M. The Putative Role of the Non-Gastric H+/K+-ATPase ATP12A (ATP1AL1) as Anti-Apoptotic Ion Transporter: Effect of the H+/K+ ATPase Inhibitor SCH28080 on Butyrate-Stimulated Myelomonocytic HL-60 Cells Cellular Physiology And Biochemistry 2014, 34: 1507-1526. PMID: 25322912, DOI: 10.1159/000366355.
Kir1.1 (ROMK) and Kv7.1 (KCNQ1/KvLQT1) are essential for normal gastric acid secretion: importance of functional Kir1.1Vucic E, Alfadda T, MacGregor GG, Dong K, Wang T, Geibel JP. Kir1.1 (ROMK) and Kv7.1 (KCNQ1/KvLQT1) are essential for normal gastric acid secretion: importance of functional Kir1.1 Pflügers Archiv - European Journal Of Physiology 2014, 467: 1457-1468. PMID: 25127675, DOI: 10.1007/s00424-014-1593-0.
Calcium-sensing receptor 20 years laterAlfadda TI, Saleh AM, Houillier P, Geibel JP. Calcium-sensing receptor 20 years later American Journal Of Physiology - Cell Physiology 2014, 307: c221-c231. PMID: 24871857, PMCID: PMC4121584, DOI: 10.1152/ajpcell.00139.2014.
758 When Tissue Is the Issue: A New Device for Extracorporeal Hypothermic Perfusion of Intestinal Lumen and Vasculature Decreases the Rate of Necrosis During Graft TransportationNarayan R, Patron-Lozano R, Loeb B, Oki K, Pancer N, Crouch A, Chauhan Y, Backus S, Fan R, Zinter J, Mulligan D, Emre S, Geibel J, Rodriguez-Davalos M. 758 When Tissue Is the Issue: A New Device for Extracorporeal Hypothermic Perfusion of Intestinal Lumen and Vasculature Decreases the Rate of Necrosis During Graft Transportation Gastroenterology 2014, 146: s-1029-s-1030. DOI: 10.1016/s0016-5085(14)63753-7.
A Novel Device to Preserve Intestinal Tissue Ex-Vivo by Cold Peristaltic PerfusionNarayan RR, Pancer NE, Loeb BW, Oki K, Crouch A, Backus S, Chauhan Y, Patrón-Lozano R, Rodriguez-Davalos MI, Geibel JP, Fan RE, Zinter JP. A Novel Device to Preserve Intestinal Tissue Ex-Vivo by Cold Peristaltic Perfusion Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2014, 2014: 3118-3121. PMID: 25570651, DOI: 10.1109/embc.2014.6944283.
Functional vacuolar ATPase (V-ATPase) proton pumps traffic to the enterocyte brush border membrane and require CFTRCollaco AM, Geibel P, Lee BS, Geibel JP, Ameen NA. Functional vacuolar ATPase (V-ATPase) proton pumps traffic to the enterocyte brush border membrane and require CFTR American Journal Of Physiology - Cell Physiology 2013, 305: c981-c996. PMID: 23986201, PMCID: PMC4109618, DOI: 10.1152/ajpcell.00067.2013.
Activation of AMPK Inhibits Cholera Toxin Stimulated Chloride Secretion in Human and Murine IntestineRogers AC, Huetter L, Hoekstra N, Collins D, Collaco A, Baird AW, Winter DC, Ameen N, Geibel JP, Kopic S. Activation of AMPK Inhibits Cholera Toxin Stimulated Chloride Secretion in Human and Murine Intestine PLOS ONE 2013, 8: e69050. PMID: 23935921, PMCID: PMC3728293, DOI: 10.1371/journal.pone.0069050.
Effect of NSAIDs on Na+/H+ exchanger activity in rat colonic cryptsRoginiel AC, Kohut DL, Kaur S, Saleh AM, Weber T, Geibel P, Singh H, Geibel JP. Effect of NSAIDs on Na+/H+ exchanger activity in rat colonic crypts American Journal Of Physiology - Cell Physiology 2013, 305: c512-c518. PMID: 23739181, DOI: 10.1152/ajpcell.00303.2012.
Identification of Functionally Distinct Na-HCO3 Co-Transporters in ColonBarmeyer C, Ye JH, Soroka C, Geibel P, Hingsammer LM, Weitgasser L, Atway D, Geibel JP, Binder HJ, Rajendran VM. Identification of Functionally Distinct Na-HCO3 Co-Transporters in Colon PLOS ONE 2013, 8: e62864. PMID: 23690961, PMCID: PMC3653958, DOI: 10.1371/journal.pone.0062864.
The calcium sensing receptor modulates fluid reabsorption and acid secretion in the proximal tubuleCapasso G, Geibel PJ, Damiano S, Jaeger P, Richards WG, Geibel JP. The calcium sensing receptor modulates fluid reabsorption and acid secretion in the proximal tubule Kidney International 2013, 84: 277-284. PMID: 23615500, DOI: 10.1038/ki.2013.137.
CFTR and V‐ATPase trafficking and function in the intestinal brush border membraneCollaco A, Geibel P, Kravtsov D, Ghantaphang S, Lee B, Geibel J, Ameen N. CFTR and V‐ATPase trafficking and function in the intestinal brush border membrane The FASEB Journal 2013, 27: 913.10-913.10. DOI: 10.1096/fasebj.27.1_supplement.913.10.
Gastric Acid, Calcium Absorption, and Their Impact on Bone HealthKopic S, Geibel JP. Gastric Acid, Calcium Absorption, and Their Impact on Bone Health Physiological Reviews 2013, 93: 189-268. PMID: 23303909, DOI: 10.1152/physrev.00015.2012.
Activation of the Ca2+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membraneJouret F, Wu J, Hull M, Rajendran V, Mayr B, Schöfl C, Geibel J, Caplan MJ. Activation of the Ca2+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane Journal Of Cell Science 2013, 126: 5132-5142. PMID: 24013548, PMCID: PMC3828589, DOI: 10.1242/jcs.127555.
Chapter 63 The Calcium-Sensing ReceptorBrown E, Hebert S, Riccardi D, Geibel J. Chapter 63 The Calcium-Sensing Receptor 2013, 2187-2224. DOI: 10.1016/b978-0-12-381462-3.00063-x.
Calcium Modulation Decreases Chloride Efflux And Cytokine Secretion In Activated Cystic Fibrosis Murine MacrophagesShenoy A, Kopic S, Bruscia E, Caputo C, Geibel J, Egan M. Calcium Modulation Decreases Chloride Efflux And Cytokine Secretion In Activated Cystic Fibrosis Murine Macrophages 2012, a5272-a5272. DOI: 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5272.
Su1617 Dopamine Can Directly Inhibit Gastric Acid SecretionSchmidt S, Geibel P, Kopic S, Ritter M, Geibel J. Su1617 Dopamine Can Directly Inhibit Gastric Acid Secretion Gastroenterology 2012, 142: s-465. DOI: 10.1016/s0016-5085(12)61761-2.
391 The Role of Calcium-Activated Chloride Channels (CaCCS) in the Process of Gastric Acid SecretionSchmidt S, Kopic S, Roberts K, Ritter M, Geibel J. 391 The Role of Calcium-Activated Chloride Channels (CaCCS) in the Process of Gastric Acid Secretion Gastroenterology 2012, 142: s-86. DOI: 10.1016/s0016-5085(12)60327-8.
Mo1829 Modulation of Bicarbonate Transport in the Proximal and Distal Colon Following Exposure to ForskolinAtway D, Geibel P, Schmidt K, Geibel J. Mo1829 Modulation of Bicarbonate Transport in the Proximal and Distal Colon Following Exposure to Forskolin Gastroenterology 2012, 142: s-694. DOI: 10.1016/s0016-5085(12)62681-x.
Effect of the AMP-Kinase Modulators AICAR, Metformin and Compound C on Insulin Secretion of INS-1E Rat Insulinoma Cells under Standard Cell Culture ConditionsLangelueddecke C, Jakab M, Ketterl N, Lehner L, Hufnagl C, Schmidt S, Geibel JP, Fuerst J, Ritter M. Effect of the AMP-Kinase Modulators AICAR, Metformin and Compound C on Insulin Secretion of INS-1E Rat Insulinoma Cells under Standard Cell Culture Conditions Cellular Physiology And Biochemistry 2012, 29: 75-86. PMID: 22415077, DOI: 10.1159/000337589.
Hypoxia Inhibits Colonic Ion Transport via Activation of AMP KinaseCollins D, Kopic S, Bachlechner J, Ritter M, Winter DC, Geibel JP. Hypoxia Inhibits Colonic Ion Transport via Activation of AMP Kinase Annals Of Surgery 2011, 254: 957-963. PMID: 21562404, DOI: 10.1097/sla.0b013e31821d477f.
Angiotensin II Stimulates H+-ATPase Activity in Intercalated Cells from Isolated Mouse Connecting Tubules and Cortical Collecting DuctsWagner CA, Mohebbi N, Uhlig U, Giebisch GH, Breton S, Brown D, Geibel JP. Angiotensin II Stimulates H+-ATPase Activity in Intercalated Cells from Isolated Mouse Connecting Tubules and Cortical Collecting Ducts Cellular Physiology And Biochemistry 2011, 28: 513-520. PMID: 22116365, PMCID: PMC3709473, DOI: 10.1159/000335112.
The Anion Exchanger Pendrin (SLC26A4) and Renal Acid-base HomeostasisWagner CA, Mohebbi N, Capasso G, Geibel JP. The Anion Exchanger Pendrin (SLC26A4) and Renal Acid-base Homeostasis Cellular Physiology And Biochemistry 2011, 28: 497-504. PMID: 22116363, DOI: 10.1159/000335111.
Vacuolar-type H+-ATPase-mediated proton transport in the rat parietal cellKopic S, Wagner ME, Griessenauer C, Socrates T, Ritter M, Geibel JP. Vacuolar-type H+-ATPase-mediated proton transport in the rat parietal cell Pflügers Archiv - European Journal Of Physiology 2011, 463: 419-427. PMID: 22146938, DOI: 10.1007/s00424-011-1060-0.
Functional role of NHE4 as a pH regulator in rat and human colonic cryptsArena EA, Longo WE, Roberts KE, Geibel P, Nateqi J, Brandstetter M, Geibel JP. Functional role of NHE4 as a pH regulator in rat and human colonic crypts American Journal Of Physiology - Cell Physiology 2011, 302: c412-c418. PMID: 22049213, DOI: 10.1152/ajpcell.00163.2011.
Calcium-Modulated Chloride Pathways Contribute to Chloride Flux in Murine Cystic Fibrosis-Affected MacrophagesSHENOY A, KOPIC S, MUREK M, CAPUTO C, GEIBEL JP, EGAN ME. Calcium-Modulated Chloride Pathways Contribute to Chloride Flux in Murine Cystic Fibrosis-Affected Macrophages Pediatric Research 2011, 70: 447-452. PMID: 21796019, PMCID: PMC3189336, DOI: 10.1203/pdr.0b013e31822f2448.
The flavonone naringenin inhibits chloride secretion in isolated colonic epitheliaCollins D, Kopic S, Geibel JP, Hogan AM, Medani M, Baird AW, Winter DC. The flavonone naringenin inhibits chloride secretion in isolated colonic epithelia European Journal Of Pharmacology 2011, 668: 271-277. PMID: 21762688, DOI: 10.1016/j.ejphar.2011.06.052.
CFTR is Necessary for Vacuolar ATPase Proton Pump (VATPase) Localization and Function in Polarized Intestinal CaCo2BBe CellsCollaco A, Geibel P, Geibel J, Ameen N. CFTR is Necessary for Vacuolar ATPase Proton Pump (VATPase) Localization and Function in Polarized Intestinal CaCo2BBe Cells Gastroenterology 2011, 140: s-645. DOI: 10.1016/s0016-5085(11)62673-5.
Activation of AMPK Inhibits Guanylin Induced Chloride Secretion in Rat ColonKopic S, Geibel P, Geibel J. Activation of AMPK Inhibits Guanylin Induced Chloride Secretion in Rat Colon Gastroenterology 2011, 140: s-133. DOI: 10.1016/s0016-5085(11)60545-3.
Modulation of Bicarbonate Transport in the Colon by Activation of AMPKinaseGeibel P, Kopic S, Geibel J. Modulation of Bicarbonate Transport in the Colon by Activation of AMPKinase Gastroenterology 2011, 140: s-662. DOI: 10.1016/s0016-5085(11)62749-2.
Insulin Antagonizes Glucose-Induced Gastric Acid Secretion via the AMP Kinase - A Reason for the High Prevalence of Peptic Ulcer Disease and GERD in DM 2?von Keudell A, Lehmann R, Kopic S, Murek M, Boroumand R, Geibel J. Insulin Antagonizes Glucose-Induced Gastric Acid Secretion via the AMP Kinase - A Reason for the High Prevalence of Peptic Ulcer Disease and GERD in DM 2? The American Journal Of Gastroenterology 2010, 105: s37. DOI: 10.14309/00000434-201010001-00097.
CaSR Mediated Gastric Acid Secretion via the Vacuolar H+-ATPase - With Special Emphasis on the Effect of Extracellular Calcium and Changes in Systemic pHSchmitt A, Bloecker K, Geibel J. CaSR Mediated Gastric Acid Secretion via the Vacuolar H+-ATPase - With Special Emphasis on the Effect of Extracellular Calcium and Changes in Systemic pH The American Journal Of Gastroenterology 2010, 105: s41. DOI: 10.14309/00000434-201010001-00109.
Update on the Mechanisms of Gastric Acid SecretionKopic S, Geibel JP. Update on the Mechanisms of Gastric Acid Secretion Current Colorectal Cancer Reports 2010, 12: 458-464. PMID: 20821079, DOI: 10.1007/s11894-010-0137-9.
Zinc Salts Provide a Novel, Prolonged and Rapid Inhibition of Gastric Acid SecretionKirchhoff P, Socrates T, Sidani S, Duffy A, Breidthardt T, Grob C, Viehl CT, Beglinger C, Oertli D, Geibel JP. Zinc Salts Provide a Novel, Prolonged and Rapid Inhibition of Gastric Acid Secretion The American Journal Of Gastroenterology 2010, 106: 62. PMID: 20736941, DOI: 10.1038/ajg.2010.327.
Toxin Mediated Diarrhea in the 21st Century: The Pathophysiology of Intestinal Ion Transport in the Course of ETEC, V. cholerae and Rotavirus InfectionKopic S, Geibel JP. Toxin Mediated Diarrhea in the 21st Century: The Pathophysiology of Intestinal Ion Transport in the Course of ETEC, V. cholerae and Rotavirus Infection Toxins 2010, 2: 2132-2157. PMID: 22069677, PMCID: PMC3153279, DOI: 10.3390/toxins2082132.
Cystic Fibrosis Transmembrane Conductance Regulator Protein And Calcium Activated Chloride Channels Mediate Chloride Efflux In Murine MacrophagesShenoy A, Kopic S, Murek M, Caputo C, Geibel J, Egan M. Cystic Fibrosis Transmembrane Conductance Regulator Protein And Calcium Activated Chloride Channels Mediate Chloride Efflux In Murine Macrophages 2010, a6575-a6575. DOI: 10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6575.
400 Capsaicin Causes Mitochondrial Proton Buffering in Parietal CellsKopic S, Murek M, Collins D, Boroumand M, Geibel J. 400 Capsaicin Causes Mitochondrial Proton Buffering in Parietal Cells Gastroenterology 2010, 138: s-59. DOI: 10.1016/s0016-5085(10)60268-5.
T1868 The Flavanone Naringenin Inhibits Epithelial Chloride Secretion in Rat and Human ColonCollins D, Hogan A, Kopic S, Boroumand M, Baird A, Geibel J, Winter D. T1868 The Flavanone Naringenin Inhibits Epithelial Chloride Secretion in Rat and Human Colon Gastroenterology 2010, 138: s-595. DOI: 10.1016/s0016-5085(10)62746-1.
M1681 Calcium-Sensing Receptor and AMP-Activated Protein Kinase Regulated Acid Secretion in the Parietal CellGreenstein A, Boroumand M, Geibel P, Geibel J. M1681 Calcium-Sensing Receptor and AMP-Activated Protein Kinase Regulated Acid Secretion in the Parietal Cell Gastroenterology 2010, 138: s-397. DOI: 10.1016/s0016-5085(10)61824-0.
M1861 Hypoxia Inhibits Chloride Secretion in Human Colon Through Activation of AMP KinaseCollins D, Kopic S, Bachlechner J, Hogan A, Geibel J, Winter D. M1861 Hypoxia Inhibits Chloride Secretion in Human Colon Through Activation of AMP Kinase Gastroenterology 2010, 138: s-434. DOI: 10.1016/s0016-5085(10)62004-5.
503 Ischemia Reduces Colonic Chloride Secretion by Activation of AMP-KinaseBachlechner J, Kopic S, Collins D, Boroumand M, Greenstein A, Geibel J. 503 Ischemia Reduces Colonic Chloride Secretion by Activation of AMP-Kinase Gastroenterology 2010, 138: s-72. DOI: 10.1016/s0016-5085(10)60329-0.
Commentary on ‘Diarrhoeal disease through enterocyte secretion: a doctrine untroubled by proof’Kopic S, Murek M, Geibel JP. Commentary on ‘Diarrhoeal disease through enterocyte secretion: a doctrine untroubled by proof’ Experimental Physiology 2010, 95: 484-485. PMID: 20233894, DOI: 10.1113/expphysiol.2009.051912.
Evidence for intestinal chloride secretionMurek M, Kopic S, Geibel J. Evidence for intestinal chloride secretion Experimental Physiology 2010, 95: 471-478. PMID: 20233891, DOI: 10.1113/expphysiol.2009.049445.
Ethanol Inhibits Gastric Acid Secretion in Rats Through Increased AMP-Kinase ActivityKopic S, Corradini S, Sidani S, Murek M, Vardanyan A, Föller M, Ritter M, Geibel JP. Ethanol Inhibits Gastric Acid Secretion in Rats Through Increased AMP-Kinase Activity Cellular Physiology And Biochemistry 2010, 25: 195-202. PMID: 20110680, DOI: 10.1159/000276553.
The calcium-sensing receptor.Geibel JP. The calcium-sensing receptor. Journal Of Nephrology 2010, 23 Suppl 16: s130-5. PMID: 21170870.
Revisiting the parietal cellKopic S, Murek M, Geibel JP. Revisiting the parietal cell American Journal Of Physiology - Cell Physiology 2009, 298: c1-c10. PMID: 19889964, DOI: 10.1152/ajpcell.00478.2009.
AMP-activated protein kinase: a physiological off switch for murine gastric acid secretionSidani S, Kopic S, Socrates T, Kirchhoff P, Föller M, Murek M, Capasso A, Geibel JP. AMP-activated protein kinase: a physiological off switch for murine gastric acid secretion Pflügers Archiv - European Journal Of Physiology 2009, 459: 39. PMID: 19621238, DOI: 10.1007/s00424-009-0698-3.
The Phytostilbene Resveratrol Induces Apoptosis in INS-1E Rat Insulinoma CellsBortolotti C, Kunit T, Moder A, Hufnagl C, Schmidt S, Hartl A, Langelueddecke C, Fürst J, Geibel J, Ritter M, Jakab M. The Phytostilbene Resveratrol Induces Apoptosis in INS-1E Rat Insulinoma Cells Cellular Physiology And Biochemistry 2009, 23: 245-254. PMID: 19471092, DOI: 10.1159/000218171.
S2063 Calcium Sensing Receptor (CaSR) Function in Intestine Epithelial Cells of Rodents and HumansGeibel P, Ballwieser D, Masoud A, Rajendren L, Boroumand M, Longo W, Roberts K, Duffy A, Geibel J. S2063 Calcium Sensing Receptor (CaSR) Function in Intestine Epithelial Cells of Rodents and Humans Gastroenterology 2009, 136: a-323. DOI: 10.1016/s0016-5085(09)61478-5.
W1541 Reduction of Dietary Zinc Leads to Hypersecretion of Acid via a Novel PathwayGrotz B, Buchinger N, Arena E, Kopic S, Murek M, Ritter M, Geibel J. W1541 Reduction of Dietary Zinc Leads to Hypersecretion of Acid via a Novel Pathway Gastroenterology 2009, 136: a-687-a-688. DOI: 10.1016/s0016-5085(09)63166-8.
S2062 Reversal of Osmotic Diarrhea Through Activation of the Rat Ileal Calcium Sensing Receptor (CaSR)Ballwieser D, Joseph R, Sauter M, Geibel J. S2062 Reversal of Osmotic Diarrhea Through Activation of the Rat Ileal Calcium Sensing Receptor (CaSR) Gastroenterology 2009, 136: a-322-a-323. DOI: 10.1016/s0016-5085(09)61477-3.
46 Capsaicin - A Potent Stimulator of Gastric Acid Secretion via Parietal Cell ActivationKopic S, Murek M, Arena E, Buchinger N, Grotz B, Geibel J. 46 Capsaicin - A Potent Stimulator of Gastric Acid Secretion via Parietal Cell Activation Gastroenterology 2009, 136: a-7. DOI: 10.1016/s0016-5085(09)60036-6.
T1975 NSAIDs: A Direct Activator of Acid Secretion in Parietal CellsArena E, Buchinger N, Grotz B, Kopic S, Murek M, Geibel J. T1975 NSAIDs: A Direct Activator of Acid Secretion in Parietal Cells Gastroenterology 2009, 136: a-612-a-613. DOI: 10.1016/s0016-5085(09)62822-5.
The Functions and Roles of the Extracellular Ca2+–Sensing Receptor along the Gastrointestinal TractGeibel JP, Hebert SC. The Functions and Roles of the Extracellular Ca2+–Sensing Receptor along the Gastrointestinal Tract Annual Review Of Physiology 2009, 71: 205-217. PMID: 19575679, DOI: 10.1146/annurev.physiol.010908.163128.
QS90. Calcium-Sensing Receptor: A Potential Off-Switch for Gastric Acid SecretionArena E, Hellmich U, Schilcher A, Geibel J. QS90. Calcium-Sensing Receptor: A Potential Off-Switch for Gastric Acid Secretion Journal Of Surgical Research 2009, 151: 286. DOI: 10.1016/j.jss.2008.11.385.
Resveratrol Inhibits Electrical Activity and Insulin Release from Insulinoma Cells by Block of Voltage-Gated Ca2+ Channels and Swelling-Dependent Cl- CurrentsJakab M, Lach S, Bacová Z, Langelüddecke C, Strbák V, Schmidt S, Iglseder E, Paulmichl M, Geibel J, Ritter M. Resveratrol Inhibits Electrical Activity and Insulin Release from Insulinoma Cells by Block of Voltage-Gated Ca2+ Channels and Swelling-Dependent Cl- Currents Cellular Physiology And Biochemistry 2008, 22: 567-578. PMID: 19088439, DOI: 10.1159/000185541.
T1829 Vesicular Pool of Sodium Hydrogen Exchanger NHE4 in Rat Stomach Plays a Role in Acid SecretionBrandstetter M, Elsayed M, Nateqi J, Geibel J. T1829 Vesicular Pool of Sodium Hydrogen Exchanger NHE4 in Rat Stomach Plays a Role in Acid Secretion Gastroenterology 2008, 134: a-572. DOI: 10.1016/s0016-5085(08)62670-0.
T1830 Functional Role of Sodium Hydrogen Exchanger NHE4 in Rat StomachNateqi J, Brandstetter M, Elsayed M, Bezerra C, Reboucas N, Geibel J. T1830 Functional Role of Sodium Hydrogen Exchanger NHE4 in Rat Stomach Gastroenterology 2008, 134: a-572. DOI: 10.1016/s0016-5085(08)62671-2.
T1874 Functional Role of the Sodium Hydrogen Exchanger Nhe4 in Human ColonArena E, Longo W, Geibel J. T1874 Functional Role of the Sodium Hydrogen Exchanger Nhe4 in Human Colon Gastroenterology 2008, 134: a-581. DOI: 10.1016/s0016-5085(08)62715-8.
Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteinsWagner CA, Loffing-Cueni D, Yan Q, Schulz N, Fakitsas P, Carrel M, Wang T, Verrey F, Geibel JP, Giebisch G, Hebert SC, Loffing J. Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins American Journal Of Physiology. Renal Physiology 2008, 294: f1373-f1380. PMID: 18322017, DOI: 10.1152/ajprenal.00613.2007.
QS66. Aldosterone Rapidly Enhances NHE4 Activation in Colonic CryptsArena E, Geibel J. QS66. Aldosterone Rapidly Enhances NHE4 Activation in Colonic Crypts Journal Of Surgical Research 2008, 144: 295. DOI: 10.1016/j.jss.2007.12.305.
CHAPTER 45 Expression, Function, and Regulation of H+,K+-ATPase in the KidneyWagner C, Geibel J. CHAPTER 45 Expression, Function, and Regulation of H+,K+-ATPase in the Kidney 2008, 1269-1276. DOI: 10.1016/b978-012088488-9.50048-6.
CHAPTER 63 The Calcium-Sensing ReceptorHebert S, Riccardi D, Geibel J. CHAPTER 63 The Calcium-Sensing Receptor 2008, 1785-1802. DOI: 10.1016/b978-012088488-9.50066-8.
Intragastric Injection of Botulinum Toxin A for the Treatment of ObesityMittermair R, Keller C, Geibel J. Intragastric Injection of Botulinum Toxin A for the Treatment of Obesity Obesity Surgery 2007, 17: 732-736. PMID: 17879570, DOI: 10.1007/s11695-007-9135-x.
SLC26A7 Can function as a chloride-loading mechanism in parietal cellsKosiek O, Busque SM, Föller M, Shcheynikov N, Kirchhoff P, Bleich M, Muallem S, Geibel JP. SLC26A7 Can function as a chloride-loading mechanism in parietal cells Pflügers Archiv - European Journal Of Physiology 2007, 454: 989-998. PMID: 17404755, DOI: 10.1007/s00424-007-0254-y.
Characteristics of rat downregulated in adenoma (rDRA) expressed in HEK 293 cellsBarmeyer C, Ye JH, Sidani S, Geibel J, Binder HJ, Rajendran VM. Characteristics of rat downregulated in adenoma (rDRA) expressed in HEK 293 cells Pflügers Archiv - European Journal Of Physiology 2007, 454: 441-450. PMID: 17492310, DOI: 10.1007/s00424-007-0213-7.
Stimulatory Pathways of the Calcium-Sensing Receptor on Acid Secretion in Freshly Isolated Human Gastric GlandsRemy C, Kirchhoff P, Hafner P, Busque S, Mueller M, Geibel J, Wagner C. Stimulatory Pathways of the Calcium-Sensing Receptor on Acid Secretion in Freshly Isolated Human Gastric Glands Cellular Physiology And Biochemistry 2007, 19: 33-42. PMID: 17310098, DOI: 10.1159/000099190.
We may be able to stop common lethal secretory diarrhea by activating the intestinal calcium sensing receptors.Geibel J. We may be able to stop common lethal secretory diarrhea by activating the intestinal calcium sensing receptors. MedGenMed : Medscape General Medicine 2007, 9: 9. PMID: 17435618, PMCID: PMC1925006.
PI3 Kinase Dependent Stimulation of Gastric Acid Secretion by DexamethasoneLang P, Schniepp R, Kirchhoff P, Socrates T, Sidani S, Geibel J. PI3 Kinase Dependent Stimulation of Gastric Acid Secretion by Dexamethasone Cellular Physiology And Biochemistry 2007, 20: 527-534. PMID: 17762179, DOI: 10.1159/000107536.
Ethanol inhibits gastric acid secretion in rats through increased AMP‐K activityCorradini S, Kopic S, Ritter M, Geibel J. Ethanol inhibits gastric acid secretion in rats through increased AMP‐K activity The FASEB Journal 2007, 21: a1317-a1317. DOI: 10.1096/fasebj.21.6.a1317-c.
ΔF508 Mutation Results in Impaired Gastric Acid Secretion*Sidani SM, Kirchhoff P, Socrates T, Stelter L, Ferreira E, Caputo C, Roberts KE, Bell RL, Egan ME, Geibel JP. ΔF508 Mutation Results in Impaired Gastric Acid Secretion* Journal Of Biological Chemistry 2006, 282: 6068-6074. PMID: 17178714, DOI: 10.1074/jbc.m608427200.
Characteristics of the K+-competitive H+,K+-ATPase inhibitor AZD0865 in isolated rat gastric glandsKirchhoff P, Andersson K, Socrates T, Sidani S, Kosiek O, Geibel J. Characteristics of the K+-competitive H+,K+-ATPase inhibitor AZD0865 in isolated rat gastric glands AJP Gastrointestinal And Liver Physiology 2006, 291: g838-g843. PMID: 16798725, DOI: 10.1152/ajpgi.00120.2006.
Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destructionGeibel J, Sritharan K, Geibel R, Geibel P, Persing JS, Seeger A, Roepke TK, Deichstetter M, Prinz C, Cheng SX, Martin D, Hebert SC. Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction Proceedings Of The National Academy Of Sciences Of The United States Of America 2006, 103: 9390-9397. PMID: 16760252, PMCID: PMC1475505, DOI: 10.1073/pnas.0602996103.
Somatostatin modulates PI3K-Akt, eNOS and NHE activity in the ciliary epitheliumGhosh S, Choritz L, Geibel J, Coca-Prados M. Somatostatin modulates PI3K-Akt, eNOS and NHE activity in the ciliary epithelium Molecular And Cellular Endocrinology 2006, 253: 63-75. PMID: 16764985, DOI: 10.1016/j.mce.2006.05.002.
The KCNE2 Potassium Channel Ancillary Subunit Is Essential for Gastric Acid Secretion*Roepke TK, Anantharam A, Kirchhoff P, Busque SM, Young JB, Geibel JP, Lerner DJ, Abbott GW. The KCNE2 Potassium Channel Ancillary Subunit Is Essential for Gastric Acid Secretion* Journal Of Biological Chemistry 2006, 281: 23740-23747. PMID: 16754665, DOI: 10.1074/jbc.m604155200.
Hypertonic Saline Attenuates Colonic Tumor Cell Metastatic Potential by Activating Transmembrane Sodium ConductanceShields CJ, Winter DC, Geibel JP, O’Sullivan G, Wang JH, Redmond HP. Hypertonic Saline Attenuates Colonic Tumor Cell Metastatic Potential by Activating Transmembrane Sodium Conductance The Journal Of Membrane Biology 2006, 211: 35-42. PMID: 16988862, DOI: 10.1007/s00232-006-0011-8.
An update on acid secretionGeibel JP, Wagner C. An update on acid secretion 2006, 156: 45-60. PMID: 16634146, DOI: 10.1007/s10254-005-0003-0.
An update on acid secretionGeibel J, Wagner C. An update on acid secretion 2006, 45-60. DOI: 10.1007/s10254-005-0003-0.
Distal tubule acidification.Geibel JP. Distal tubule acidification. Journal Of Nephrology 2006, 19 Suppl 9: s18-26. PMID: 16736436.
Role of calcium and other trace elements in the gastrointestinal physiologyKirchhoff P, Geibel J. Role of calcium and other trace elements in the gastrointestinal physiology World Journal Of Gastroenterology 2006, 12: 3229-3236. PMID: 16718844, PMCID: PMC4087967, DOI: 10.3748/wjg.v12.i20.3229.
An amino acid transporter involved in gastric acid secretionKirchhoff P, Dave MH, Remy C, Kosiek O, Busque SM, Dufner M, Geibel JP, Verrey F, Wagner CA. An amino acid transporter involved in gastric acid secretion Pflügers Archiv - European Journal Of Physiology 2005, 451: 738-748. PMID: 16308696, DOI: 10.1007/s00424-005-1507-2.
The B1-subunit of the H+ ATPase is required for maximal urinary acidificationFinberg KE, Wagner CA, Bailey MA, Păunescu T, Breton S, Brown D, Giebisch G, Geibel JP, Lifton RP. The B1-subunit of the H+ ATPase is required for maximal urinary acidification Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 13616-13621. PMID: 16174750, PMCID: PMC1224669, DOI: 10.1073/pnas.0506769102.
Regulation of colonic crypt fluid and electrolyte secretion by the calcium sensing receptorOsigweh J, Longo W, Dudrick S, Geibel J. Regulation of colonic crypt fluid and electrolyte secretion by the calcium sensing receptor Journal Of The American College Of Surgeons 2005, 201: s17. DOI: 10.1016/j.jamcollsurg.2005.06.026.
The calcium-sensing receptor acts as a modulator of gastric acid secretion in freshly isolated human gastric glandsDufner MM, Kirchhoff P, Remy C, Hafner P, Müller M, Cheng SX, Tang LQ, Hebert SC, Geibel JP, Wagner CA. The calcium-sensing receptor acts as a modulator of gastric acid secretion in freshly isolated human gastric glands AJP Gastrointestinal And Liver Physiology 2005, 289: g1084-g1090. PMID: 16109841, DOI: 10.1152/ajpgi.00571.2004.
l-Type amino acids stimulate gastric acid secretion by activation of the calcium-sensing receptor in parietal cellsBusque SM, Kerstetter JE, Geibel JP, Insogna K. l-Type amino acids stimulate gastric acid secretion by activation of the calcium-sensing receptor in parietal cells AJP Gastrointestinal And Liver Physiology 2005, 289: g664-g669. PMID: 15961860, DOI: 10.1152/ajpgi.00096.2005.
Bicarbonate SecretionBinder HJ, Rajendran V, Sadasivan V, Geibel JP. Bicarbonate Secretion Journal Of Clinical Gastroenterology 2005, 39: s53-s58. PMID: 15758660, DOI: 10.1097/01.mcg.0000155521.81382.3a.
SECRETION AND ABSORPTION BY COLONIC CRYPTSGeibel JP. SECRETION AND ABSORPTION BY COLONIC CRYPTS Annual Review Of Physiology 2005, 67: 471-490. PMID: 15709966, DOI: 10.1146/annurev.physiol.67.031103.153530.
Role of short-chain fatty acids in colonic HCO3 secretionVidyasagar S, Barmeyer C, Geibel J, Binder HJ, Rajendran VM. Role of short-chain fatty acids in colonic HCO3 secretion AJP Gastrointestinal And Liver Physiology 2005, 288: g1217-g1226. PMID: 15677553, DOI: 10.1152/ajpgi.00415.2004.
Insulin Receptor (IR) and Glucose Transporter 2 (GLUT2) Proteins Form a Complex on the Rat Hepatocyte MembraneEisenberg M, Maker A, Slezak L, Nathan J, Sritharan K, Jena B, Geibel J, Andersen D. Insulin Receptor (IR) and Glucose Transporter 2 (GLUT2) Proteins Form a Complex on the Rat Hepatocyte Membrane Cellular Physiology And Biochemistry 2005, 15: 051-058. PMID: 15665515, DOI: 10.1159/000083638.
Fluorescent imaging of Cl- in Amphiuma red blood cells: How the nuclear exclusion of Cl- affects the plasma membrane potentialHoffman JF, Geibel JP. Fluorescent imaging of Cl- in Amphiuma red blood cells: How the nuclear exclusion of Cl- affects the plasma membrane potential Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 921-926. PMID: 15637151, PMCID: PMC545567, DOI: 10.1073/pnas.0408597102.
Role of potassium in acid secretionGeibel JP. Role of potassium in acid secretion World Journal Of Gastroenterology 2005, 11: 5259-5265. PMID: 16149129, PMCID: PMC4622792, DOI: 10.3748/wjg.v11.i34.5259.
Renal Vacuolar H+-ATPaseWagner CA, Finberg KE, Breton S, Marshansky V, Brown D, Geibel JP. Renal Vacuolar H+-ATPase Physiological Reviews 2004, 84: 1263-1314. PMID: 15383652, DOI: 10.1152/physrev.00045.2003.
Inhibition of NHE-1 Na+/H+ exchanger by natriuretic peptides in ocular nonpigmented ciliary epitheliumFidzinski P, Salvador-Silva M, Choritz L, Geibel J, Coca-Prados M. Inhibition of NHE-1 Na+/H+ exchanger by natriuretic peptides in ocular nonpigmented ciliary epithelium American Journal Of Physiology - Cell Physiology 2004, 287: c655-c663. PMID: 15140751, DOI: 10.1152/ajpcell.00552.2003.
Functions and roles of the extracellular Ca2+-sensing receptor in the gastrointestinal tractHebert SC, Cheng S, Geibel J. Functions and roles of the extracellular Ca2+-sensing receptor in the gastrointestinal tract Cell Calcium 2004, 35: 239-247. PMID: 15200147, DOI: 10.1016/j.ceca.2003.10.015.
Nongenomic stimulation of vacuolar H+-ATPases in intercalated renal tubule cells by aldosteroneWinter C, Schulz N, Giebisch G, Geibel JP, Wagner CA. Nongenomic stimulation of vacuolar H+-ATPases in intercalated renal tubule cells by aldosterone Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 2636-2641. PMID: 14983061, PMCID: PMC357002, DOI: 10.1073/pnas.0307321101.
Extracellular polyamines regulate fluid secretion in rat colonic crypts via the extracellular calcium-sensing receptorCheng SX, Geibel JP, Hebert SC. Extracellular polyamines regulate fluid secretion in rat colonic crypts via the extracellular calcium-sensing receptor Gastroenterology 2004, 126: 148-158. PMID: 14699496, DOI: 10.1053/j.gastro.2003.10.064.
Localization and Regulation of the ATP6V0A4 (a4) Vacuolar H+-ATPase Subunit Defective in an Inherited Form of Distal Renal Tubular AcidosisStehberger PA, Schulz N, Finberg KE, Karet FE, Giebisch G, Lifton RP, Geibel JP, Wagner CA. Localization and Regulation of the ATP6V0A4 (a4) Vacuolar H+-ATPase Subunit Defective in an Inherited Form of Distal Renal Tubular Acidosis Journal Of The American Society Of Nephrology 2003, 14: 3027-3038. PMID: 14638902, DOI: 10.1097/01.asn.0000099375.74789.ab.
Intracellular pH Activates Membrane-Bound Na+/H+ Exchanger and Vacuolar H+-ATPase in Human Embryonic Kidney (HEK) CellsLang K, Wagner C, Haddad G, Burnekova O, Geibel J. Intracellular pH Activates Membrane-Bound Na+/H+ Exchanger and Vacuolar H+-ATPase in Human Embryonic Kidney (HEK) Cells Cellular Physiology And Biochemistry 2003, 13: 257-262. PMID: 14586169, DOI: 10.1159/000074540.
Molecular cloning and characterization of Atp6v1b1, the murine vacuolar H+-ATPase B1-subunitFinberg KE, Wagner CA, Stehberger PA, Geibel JP, Lifton RP. Molecular cloning and characterization of Atp6v1b1, the murine vacuolar H+-ATPase B1-subunit Gene 2003, 318: 25-34. PMID: 14585495, DOI: 10.1016/s0378-1119(03)00790-x.
Demonstration of a functional apical sodium hydrogen exchanger in isolated rat gastric glandsKirchhoff P, Wagner CA, Gaetzschmann F, Radebold K, Geibel JP. Demonstration of a functional apical sodium hydrogen exchanger in isolated rat gastric glands AJP Gastrointestinal And Liver Physiology 2003, 285: g1242-g1248. PMID: 12907430, DOI: 10.1152/ajpgi.00165.2003.
Characterization of Cl-HCO3 exchange in basolateral membrane of rat distal colonIkuma M, Geibel J, Binder HJ, Rajendran VM. Characterization of Cl-HCO3 exchange in basolateral membrane of rat distal colon American Journal Of Physiology - Cell Physiology 2003, 285: c912-c921. PMID: 12826602, DOI: 10.1152/ajpcell.00396.2002.
A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouseWagner CA, Lükewille U, Valles P, Breton S, Brown D, Giebisch GH, Geibel JP. A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouse Pflügers Archiv - European Journal Of Physiology 2003, 446: 623-632. PMID: 12748863, DOI: 10.1007/s00424-003-1082-3.
CFTR plays a major role in acid secretion in gastric glandsStelter L, Kirchhoff P, Boucher R, Grubb B, Wagner C, Egan M, Geibel J. CFTR plays a major role in acid secretion in gastric glands Gastroenterology 2003, 124: a443. DOI: 10.1016/s0016-5085(03)82240-0.
Ethanol induced inhibition of gastric acid secretion is mediated via the soluble adenylate cyclase (sAC)Radebold K, Vucic E, Geibel J. Ethanol induced inhibition of gastric acid secretion is mediated via the soluble adenylate cyclase (sAC) Gastroenterology 2003, 124: a301. DOI: 10.1016/s0016-5085(03)81518-4.
Polyamines interact with the Ca2+ sensing receptor (CaSR) to modulate fluid secretion by rat colonic epitheliumCheng S, Geibel J, Hebert S. Polyamines interact with the Ca2+ sensing receptor (CaSR) to modulate fluid secretion by rat colonic epithelium Gastroenterology 2003, 124: a609. DOI: 10.1016/s0016-5085(03)83087-1.
Soluble Adenylyl Cyclase (sAC) is an important mediator for gastrin, histamine and carbachol stimulated acid secretion in rat parietal cellsVucic E, Radebold K, Wagner C, Litvin T, Levin L, Buck J, Geibel J. Soluble Adenylyl Cyclase (sAC) is an important mediator for gastrin, histamine and carbachol stimulated acid secretion in rat parietal cells Gastroenterology 2003, 124: a467. DOI: 10.1016/s0016-5085(03)82360-0.
The stomach-calcium-sensing-receptor(SCAR)decreases NHE activity during gastric acid secretinKirchhoff P, Vucic E, Stelter L, Geibel J. The stomach-calcium-sensing-receptor(SCAR)decreases NHE activity during gastric acid secretin Gastroenterology 2003, 124: a443. DOI: 10.1016/s0016-5085(03)82239-4.
Na-H Exchange Function in Colonic Epithelial CellsBinder H, Rajendran V, Geibel J. Na-H Exchange Function in Colonic Epithelial Cells 2003, 71-90. DOI: 10.1007/978-1-4615-0427-6_5.
Cellular Mechanisms and Physiology of Nucleotide and Nucleoside Release from Cells: Current Knowledge, Novel Assays to Detect Purinergic Agonists, and Future DirectionsSchwiebert E, Zsembery A, Geibel J. Cellular Mechanisms and Physiology of Nucleotide and Nucleoside Release from Cells: Current Knowledge, Novel Assays to Detect Purinergic Agonists, and Future Directions 2003, 54: 31-58. DOI: 10.1016/s1063-5823(03)01002-0.
Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base statusWagner CA, Finberg KE, Stehberger PA, Lifton RP, Giebisch GH, Aronson PS, Geibel JP. Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status Kidney International 2002, 62: 2109-2117. PMID: 12427135, DOI: 10.1046/j.1523-1755.2002.00671.x.
Expression of calcium-sensing receptor in rat colonic epithelium: evidence for modulation of fluid secretionCheng SX, Okuda M, Hall AE, Geibel JP, Hebert SC. Expression of calcium-sensing receptor in rat colonic epithelium: evidence for modulation of fluid secretion AJP Gastrointestinal And Liver Physiology 2002, 283: g240-g250. PMID: 12065312, DOI: 10.1152/ajpgi.00500.2001.
Calcium-pump inhibitors induce functional surface expression of ΔF508-CFTR protein in cystic fibrosis epithelial cellsEgan ME, Glöckner-Pagel J, Ambrose C, Cahill PA, Pappoe L, Balamuth N, Cho E, Canny S, Wagner CA, Geibel J, Caplan MJ. Calcium-pump inhibitors induce functional surface expression of ΔF508-CFTR protein in cystic fibrosis epithelial cells Nature Medicine 2002, 8: 485-492. PMID: 11984593, DOI: 10.1038/nm0502-485.
Acid-base transport in the collecting duct.Wagner CA, Geibel JP. Acid-base transport in the collecting duct. Journal Of Nephrology 2002, 15 Suppl 5: s112-27. PMID: 12027210.
Microscopy as a tool for renal research.Geibel JP. Microscopy as a tool for renal research. Journal Of Nephrology 2002, 15 Suppl 5: s161-9. PMID: 12027215.
Cloning and Expression of a Chloride-dependent Na+-H+ Exchanger*Sangan P, Rajendran VM, Geibel JP, Binder HJ. Cloning and Expression of a Chloride-dependent Na+-H+ Exchanger* Journal Of Biological Chemistry 2001, 277: 9668-9675. PMID: 11773056, DOI: 10.1074/jbc.m110852200.
Gap Junctional Channels Regulate Acid Secretion in the Mammalian Gastric GlandRadebold K, Horakova E, Gloeckner J, Ortega G, Spray D, Vieweger H, Siebert K, Manuelidis L, Geibel J. Gap Junctional Channels Regulate Acid Secretion in the Mammalian Gastric Gland The Journal Of Membrane Biology 2001, 183: 147-153. PMID: 11696856, DOI: 10.1007/s00232-001-0062-9.
The Stomach Divalent Ion-sensing Receptor SCAR Is a Modulator of Gastric Acid Secretion*Geibel J, Wagner C, Caroppo R, Qureshi I, Gloeckner J, Manuelidis L, Kirchhoff P, Radebold K. The Stomach Divalent Ion-sensing Receptor SCAR Is a Modulator of Gastric Acid Secretion* Journal Of Biological Chemistry 2001, 276: 39549-39552. PMID: 11507103, DOI: 10.1074/jbc.m107315200.
Effects of the Serine/Threonine Kinase SGK1 on the Epithelial Na+ Channel (ENaC) and CFTR: Implications for Cystic FibrosisWagner C, Ott M, Klingel K, Beck S, Melzig J, Friedrich B, Wild K, Bröer S, Moschen I, Albers A, Waldegger S, Tümmler B, Egan M, Geibel J, Kandolf R, Lang F. Effects of the Serine/Threonine Kinase SGK1 on the Epithelial Na+ Channel (ENaC) and CFTR: Implications for Cystic Fibrosis Cellular Physiology And Biochemistry 2001, 11: 209-218. PMID: 11509829, DOI: 10.1159/000051935.
K+-induced HSP-72 expression is mediated via rapid Ca2+ influx in renal epithelial cellsEickelberg O, Geibel J, Seebach F, Giebisch G, Kashgarian M. K+-induced HSP-72 expression is mediated via rapid Ca2+ influx in renal epithelial cells American Journal Of Physiology. Renal Physiology 2001, 281: f280-f287. PMID: 11457719, DOI: 10.1152/ajprenal.2001.281.2.f280.
Stimulation of the colonic divalent cation receptor leads to a down regulation in basolateral NKCC transportGeibel P, O'Reilly M, Vieweger H, Siebert K, O'Brein N, Cheng S, Hebert S, Binder H, Geibel J. Stimulation of the colonic divalent cation receptor leads to a down regulation in basolateral NKCC transport Gastroenterology 2001, 120: a529. DOI: 10.1016/s0016-5085(08)82628-5.
Stimulation of the colonic divalent cation receptor leads to a down regulation in basolateral NKCC transportGEIBEL P, OREILLY M, VIEWEGER H, SIEBERT K, OBREIN N, CHENG S, HEBERT S, BINDER H, GEIBEL J. Stimulation of the colonic divalent cation receptor leads to a down regulation in basolateral NKCC transport Gastroenterology 2001, 120: a529-a529. DOI: 10.1016/s0016-5085(01)82628-7.
Demonstration of a basolateral NHE3 exchanger in isolated rat gastric glandsRadebold K, Hansen M, Geibel J. Demonstration of a basolateral NHE3 exchanger in isolated rat gastric glands Gastroenterology 2001, 120: a157. DOI: 10.1016/s0016-5085(08)80775-5.
Colocalization of insulin receptor (IR) and glucose transporter 2 (GLUT2) proteins in rat hepatocytesEisenberg M, Maker A, Sritharan K, Geibel J, Andersen D. Colocalization of insulin receptor (IR) and glucose transporter 2 (GLUT2) proteins in rat hepatocytes Gastroenterology 2001, 120: a309. DOI: 10.1016/s0016-5085(08)81532-6.
Functional expression of an extracellular calcium-sensing receptor in rat colonCheng S, Hall A, Okuda M, Geibel J, Hebert S. Functional expression of an extracellular calcium-sensing receptor in rat colon Gastroenterology 2001, 120: a511. DOI: 10.1016/s0016-5085(08)82538-3.
Demonstration of a direct interaction between a colonic divalent cation receptor and the basolateral Na−H exchangerGeibel P, O'Reilly M, Vieweger H, Siebert K, O'Brein N, Cheng S, Hebert S, Geibel J. Demonstration of a direct interaction between a colonic divalent cation receptor and the basolateral Na−H exchanger Gastroenterology 2001, 120: a529-a530. DOI: 10.1016/s0016-5085(08)82630-3.
ROMK is the apical membrane K+ recycling pathway in the gastric giandSritharan K, Wagner C, Dong K, Radebold K, Hebert S, Geibel J. ROMK is the apical membrane K+ recycling pathway in the gastric giand Gastroenterology 2001, 120: a102. DOI: 10.1016/s0016-5085(08)80500-8.
ROMK is the apical membrane K+ recycling pathway in the gastric giandSRITHARAN K, WAGNER C, DONG K, RADEBOLD K, HEBERT S, GEIBEL J. ROMK is the apical membrane K+ recycling pathway in the gastric giand Gastroenterology 2001, 120: a102-a102. DOI: 10.1016/s0016-5085(01)80500-x.
Demonstration of a basolateral NHE3 exchanger in isolated rat gastric glandsRADEBOLD K, HANSEN M, GEIBEL J. Demonstration of a basolateral NHE3 exchanger in isolated rat gastric glands Gastroenterology 2001, 120: a157-a157. DOI: 10.1016/s0016-5085(01)80775-7.
Colocalization of insulin receptor (IR) and glucose transporter 2 (GLUT2) proteins in rat hepatocytesEISENBERG M, MAKER A, SRITHARAN K, GEIBEL J, ANDERSEN D. Colocalization of insulin receptor (IR) and glucose transporter 2 (GLUT2) proteins in rat hepatocytes Gastroenterology 2001, 120: a309-a309. DOI: 10.1016/s0016-5085(01)81532-8.
Demonstration of a direct interaction between a colonic divalent cation receptor and the basolateral Na−H exchangerGEIBEL P, OREILLY M, VIEWEGER H, SIEBERT K, OBREIN N, CHENG S, HEBERT S, GEIBEL J. Demonstration of a direct interaction between a colonic divalent cation receptor and the basolateral Na−H exchanger Gastroenterology 2001, 120: a529-a530. DOI: 10.1016/s0016-5085(01)82630-5.
Characterization of apical membrane Cl-dependent Na/H exchange in crypt cells of rat distal colonRajendran V, Geibel J, Binder H. Characterization of apical membrane Cl-dependent Na/H exchange in crypt cells of rat distal colon AJP Gastrointestinal And Liver Physiology 2001, 280: g400-g405. PMID: 11171622, DOI: 10.1152/ajpgi.2001.280.3.g400.
Impaired Hepatocyte Glucose Transport Protein (GLUT2) Internalization in Chronic PancreatitisNathan J, Zdankiewicz P, Wang J, Spector S, Aspelund G, Jena B, Seymour N, Geibel J, Andersen D. Impaired Hepatocyte Glucose Transport Protein (GLUT2) Internalization in Chronic Pancreatitis Pancreas 2001, 22: 172-178. PMID: 11249072, DOI: 10.1097/00006676-200103000-00010.
Na+-dependent fluid absorption in intact perfused rat colonic cryptsGeibel J, Rajendran V, Binder H. Na+-dependent fluid absorption in intact perfused rat colonic crypts Gastroenterology 2001, 120: 144-150. PMID: 11208723, DOI: 10.1053/gast.2001.20890.
Cell pH and H+ Secretion by S3 Segment of Mammalian Kidney: Role of H+-ATPase and Cl−Malnic G, Geibel J. Cell pH and H+ Secretion by S3 Segment of Mammalian Kidney: Role of H+-ATPase and Cl− The Journal Of Membrane Biology 2000, 178: 115-125. PMID: 11083900, DOI: 10.1007/s002320010019.
Gap junctional protins play an important regulatory role in mouse gastric acid secretionRadebold K, Wojdermann M, Zaitsev I, Gloeckner J, Spicer Z, Shull G, Manuelidis L, Geibel J. Gap junctional protins play an important regulatory role in mouse gastric acid secretion Gastroenterology 2000, 118: a32. DOI: 10.1016/s0016-5085(00)82198-8.
Ouabain-sensitive H,K-ATPase Functions as Na,K-ATPase in Apical Membranes of Rat Distal Colon*Rajendran V, Sangan P, Geibel J, Binder H. Ouabain-sensitive H,K-ATPase Functions as Na,K-ATPase in Apical Membranes of Rat Distal Colon* Journal Of Biological Chemistry 2000, 275: 13035-13040. PMID: 10777607, DOI: 10.1074/jbc.275.17.13035.
Histamine activates intracellular calcium by dual signaling cascades in parietal cells of miceWojdemann M, Radebold K, Spicer Z, Shull G, Geibel J. Histamine activates intracellular calcium by dual signaling cascades in parietal cells of mice Gastroenterology 2000, 118: a1324. DOI: 10.1016/s0016-5085(00)81160-9.
The stimulation of gastric acid secretion in mice is dependent on a divalent cation receptorRadebold K, Wojdemann M, Spicer Z, Shull G, Geibel J. The stimulation of gastric acid secretion in mice is dependent on a divalent cation receptor Gastroenterology 2000, 118: a1298. DOI: 10.1016/s0016-5085(00)81049-5.
Calcium dependent stimulation of gastric acid secretion in wild-type and H+/K+-ATPase knock-out miceWojdemann M, Radebold K, Spicer Z, Shull G, Geibel J. Calcium dependent stimulation of gastric acid secretion in wild-type and H+/K+-ATPase knock-out mice Gastroenterology 2000, 118: a1324. DOI: 10.1016/s0016-5085(00)81159-2.
H+/K+-ATPase deficient mice employ an alternative acid secretory pathwayWojdemann M, Radebold K, Spicer Z, Shull G, Geibel J. H+/K+-ATPase deficient mice employ an alternative acid secretory pathway Gastroenterology 2000, 118: a34. DOI: 10.1016/s0016-5085(00)82207-6.
Calcium, ATP and nuclear pore channel gatingBustamante J, Michelette E, Geibel J, Dean D, Hanover J, McDonnell T. Calcium, ATP and nuclear pore channel gating Pflügers Archiv - European Journal Of Physiology 2000, 439: 433-444. PMID: 10678739, PMCID: PMC4400178, DOI: 10.1007/s004249900189.
Dendrimer-assisted patch-clamp sizing of nuclear poresBustamante J, Michelette E, Geibel J, Hanover J, McDonnell T, Dean D. Dendrimer-assisted patch-clamp sizing of nuclear pores Pflügers Archiv - European Journal Of Physiology 2000, 439: 829-837. PMID: 10784359, PMCID: PMC4397974, DOI: 10.1007/s004249900233.
Cl‐Dependent Na‐H Exchange: A Novel Colonic Crypt Transport MechanismBINDER H, RAJENDRAN V, GEIBEL J. Cl‐Dependent Na‐H Exchange: A Novel Colonic Crypt Transport Mechanism Annals Of The New York Academy Of Sciences 2000, 915: 43-53. PMID: 11193600, DOI: 10.1111/j.1749-6632.2000.tb05222.x.
Direct observation of oxidative stress on the cell wall of Saccharomyces cerevisiae strains with atomic force microscopyde Souza Pereira R, Geibel J. Direct observation of oxidative stress on the cell wall of Saccharomyces cerevisiae strains with atomic force microscopy Molecular And Cellular Biochemistry 1999, 201: 17-24. PMID: 10630618, DOI: 10.1023/a:1007007704657.
Continuous detection of extracellular ATP on living cells by using atomic force microscopySchneider S, Egan M, Jena B, Guggino W, Oberleithner H, Geibel J. Continuous detection of extracellular ATP on living cells by using atomic force microscopy Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 12180-12185. PMID: 10518596, PMCID: PMC18432, DOI: 10.1073/pnas.96.21.12180.
Thresholds for cellular disruption and activation of the stress response in renal epitheliavan Why S, Kim S, Geibel J, Seebach F, Kashgarian M, Siegel N. Thresholds for cellular disruption and activation of the stress response in renal epithelia American Journal Of Physiology 1999, 277: f227-f234. PMID: 10444577, DOI: 10.1152/ajprenal.1999.277.2.f227.
Rapid Effects of Aldosterone on Sodium-Hydrogen Exchange in Isolated Colonic CryptsWinter D, Schneider M, O'Sullivan G, Harvey B, Geibel J. Rapid Effects of Aldosterone on Sodium-Hydrogen Exchange in Isolated Colonic Crypts The Journal Of Membrane Biology 1999, 170: 17-26. PMID: 10398757, DOI: 10.1007/s002329900534.
Direct Effects of Dopamine on Colonic Mucosal pH: Implications for TonometryWinter D, O'Sullivan G, Harvey B, Geibel J. Direct Effects of Dopamine on Colonic Mucosal pH: Implications for Tonometry Journal Of Surgical Research 1999, 83: 62-68. PMID: 10210644, DOI: 10.1006/jsre.1998.5561.
Introduction to use of atomic force microscopy and optical tweezers in biologyJena B, Geibel J, Schneider S. Introduction to use of atomic force microscopy and optical tweezers in biology Microscopy Research And Technique 1999, 44: 311-311. DOI: 10.1002/(sici)1097-0029(19990301)44:5<311::aid-jemt1>3.0.co;2-t.
Role of Cl channels in Cl-dependent Na/H exchangeRajendran V, Geibel J, Binder H. Role of Cl channels in Cl-dependent Na/H exchange American Journal Of Physiology 1999, 276: g73-g78. PMID: 9886981, DOI: 10.1152/ajpgi.1999.276.1.g73.
Expression of an extracellular calcium-sensing receptor in rat stomachCheng* ‡, Qureshi§ I, Chattopadhyay‡ N, Qureshi§ A, Butters‡ R, Hall∥ A, Cima* R, Rogers∥ K, Hebert∥ S, Geibel§ J, Brown‡ E, Soybel* D, ¶NPS Pharmaceuticals I. Expression of an extracellular calcium-sensing receptor in rat stomach Gastroenterology 1999, 116: 118-126. PMID: 9869609, DOI: 10.1016/s0016-5085(99)70235-0.
Role of Apical H-K Exchange and Basolateral K Channel in the Regulation of Intracellular pH in Rat Distal Colon Crypt CellsIkuma M, Binder H, Geibel J. Role of Apical H-K Exchange and Basolateral K Channel in the Regulation of Intracellular pH in Rat Distal Colon Crypt Cells The Journal Of Membrane Biology 1998, 166: 205-212. PMID: 9843594, DOI: 10.1007/s002329900462.
Angiotensin II stimulates vesicular H+-ATPase in rat proximal tubular cellsWagner C, Giebisch G, Lang F, Geibel J. Angiotensin II stimulates vesicular H+-ATPase in rat proximal tubular cells Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 9665-9668. PMID: 9689138, PMCID: PMC21396, DOI: 10.1073/pnas.95.16.9665.
Sorting of P-type ATPases in polarized epithelial cells.Dunbar LA, Courtois-Coutry N, Roush DL, Muth TR, Gottardi CJ, Rajendran V, Geibel J, Kashgarian M, Caplan MJ. Sorting of P-type ATPases in polarized epithelial cells. Acta Physiologica Scandinavica. Supplementum 1998, 643: 289-95. PMID: 9789572.
Cl−HCO3 and Cl−OH exchanges of basolateral membranes (BLM) regulate intracellular pH (pHi) in crypt cells of rat distal colonIkuma M, Geibel J, Binder H, Rajendran V. Cl−HCO3 and Cl−OH exchanges of basolateral membranes (BLM) regulate intracellular pH (pHi) in crypt cells of rat distal colon Gastroenterology 1998, 114: a380. DOI: 10.1016/s0016-5085(98)81539-4.
The role of intracellular calcium in cholera toxin-mediated chloride secretion in colonic cryptsOureshi A, Ikuma M, Rodas E, Ortega G, Geibel J. The role of intracellular calcium in cholera toxin-mediated chloride secretion in colonic crypts Gastroenterology 1998, 114: a407. DOI: 10.1016/s0016-5085(98)81648-x.
Demonstration of gap junctional protein connexin 32 and connexin 26 among parietal cells of mammalian gastric glandsOrtega G, Caroppo R, Rodas E, Qureshi A, Spray D, Gao Y, Geibel J. Demonstration of gap junctional protein connexin 32 and connexin 26 among parietal cells of mammalian gastric glands Gastroenterology 1998, 114: a1171. DOI: 10.1016/s0016-5085(98)84762-8.
Effects of cholera toxin on chloride transport mechanisms in the basolateral membrane of colonic cryptsOureshi A, Ortega G, Rodas E, Geibel J. Effects of cholera toxin on chloride transport mechanisms in the basolateral membrane of colonic crypts Gastroenterology 1998, 114: a407. DOI: 10.1016/s0016-5085(98)81647-8.
Identification of the ROMK channel in mammalian parietal cellsRodas E, Ortega G, Qureshi A, MacGregor G, Xu J, Hebert S, Geibel J. Identification of the ROMK channel in mammalian parietal cells Gastroenterology 1998, 114: a269. DOI: 10.1016/s0016-5085(98)81093-7.
Immunolocalization of the Na-HCO3 cotransporter (NBC) in rat gastric parietal cellsCaroppo R, Schmitt B, Boron W, Geibel J. Immunolocalization of the Na-HCO3 cotransporter (NBC) in rat gastric parietal cells Gastroenterology 1998, 114: a1132-a1133. DOI: 10.1016/s0016-5085(98)84605-2.
Differential localization of colonic H+-K+-ATPase isoforms in surface and crypt cellsRajendran V, Singh S, Geibel J, Binder H. Differential localization of colonic H+-K+-ATPase isoforms in surface and crypt cells American Journal Of Physiology 1998, 274: g424-g429. PMID: 9486199, DOI: 10.1152/ajpgi.1998.274.2.g424.
Atomic Force Microscopy on Living Cells: Aldosterone–Induced Localized Cell SwellingSchneider SW, Pagel P, Storck J, Yano Y, Sumpio BE, Geibel JP, Oberleithner H. Atomic Force Microscopy on Living Cells: Aldosterone–Induced Localized Cell Swelling Kidney & Blood Pressure Research 1998, 21: 256-258. PMID: 9762848, DOI: 10.1159/000025869.
Gi regulation of secretory vesicle swelling examined by atomic force microscopyJena B, Schneider S, Geibel J, Webster P, Oberleithner H, Sritharan K. Gi regulation of secretory vesicle swelling examined by atomic force microscopy Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 13317-13322. PMID: 9371843, PMCID: PMC24306, DOI: 10.1073/pnas.94.24.13317.
Sorting of Ion Pumps in Polarized Epithelial Cells.aDUNBAR L, ROUSH D, COURTOIS‐COUTRY N, MUTH T, GOTTARDI CJ, RAJENDRAN V, GEIBEL J, KASHGARIAN M, CAPLAN M. Sorting of Ion Pumps in Polarized Epithelial Cells.a Annals Of The New York Academy Of Sciences 1997, 834: 514-523. PMID: 9405853, DOI: 10.1111/j.1749-6632.1997.tb52309.x.
RAPID ALDOSTERONE‐INDUCED CELL VOLUME INCREASE OF ENDOTHELIAL CELLS MEASURED BY THE ATOMIC FORCE MICROSCOPESCHNEIDER S, YANO Y, SUMPIO B, JENA B, GEIBEL J, GEKLE M, OBERLEITHNER H. RAPID ALDOSTERONE‐INDUCED CELL VOLUME INCREASE OF ENDOTHELIAL CELLS MEASURED BY THE ATOMIC FORCE MICROSCOPE Cell Biology International 1997, 21: 759-768. PMID: 9768474, DOI: 10.1006/cbir.1997.0220.
AN ATOMIC FORCE MICROSCOPIC EXAMINATION OF THE APICAL MEMBRANE OF THE MAMMALIAN GASTRIC GLANDGEIBEL J. AN ATOMIC FORCE MICROSCOPIC EXAMINATION OF THE APICAL MEMBRANE OF THE MAMMALIAN GASTRIC GLAND Cell Biology International 1997, 21: 727-736. PMID: 9768471, DOI: 10.1006/cbir.1997.0217.
Novel Transport Properties of Colonic Crypt Cells: Fluid Absorption and Cl-Dependent Na-H ExchangeBinder H, Singh S, Geibel J, Rajendran V. Novel Transport Properties of Colonic Crypt Cells: Fluid Absorption and Cl-Dependent Na-H Exchange Comparative Biochemistry And Physiology Part A Molecular & Integrative Physiology 1997, 118: 265-269. PMID: 9366054, DOI: 10.1016/s0300-9629(97)00079-0.
Intracellular Acidification Induces Cl/HCO3 Exchange Activity in the Basolateral Membrane of β-intercalated Cells of the Rabbit Cortical Collecting DuctMerot J, Giebisch G, Geibel J. Intracellular Acidification Induces Cl/HCO3 Exchange Activity in the Basolateral Membrane of β-intercalated Cells of the Rabbit Cortical Collecting Duct The Journal Of Membrane Biology 1997, 159: 253-262. PMID: 9312214, DOI: 10.1007/s002329900288.
Differential activities of H+extrusion systems in MDCK cells due to extracellular osmolality and pHFeifel E, Krall M, Geibel J, Pfaller W. Differential activities of H+extrusion systems in MDCK cells due to extracellular osmolality and pH American Journal Of Physiology 1997, 273: f499-f506. PMID: 9362327, DOI: 10.1152/ajprenal.1997.273.4.f499.
A Tyrosine-Based Signal Targets H/K-ATPase to a Regulated Compartment and Is Required for the Cessation of Gastric Acid SecretionCourtois-Coutry N, Roush D, Rajendran V, McCarthy J, Geibel J, Kashgarian M, Caplan M. A Tyrosine-Based Signal Targets H/K-ATPase to a Regulated Compartment and Is Required for the Cessation of Gastric Acid Secretion Cell 1997, 90: 501-510. PMID: 9267030, DOI: 10.1016/s0092-8674(00)80510-3.
LOCALIZATION OF SH‐PTP1 TO SYNAPTIC VESICLES: A POSSIBLE ROLE IN NEUROTRANSMISSIONJENA B, WEBSTER P, GEIBEL J, POL A, SRITHARAN K. LOCALIZATION OF SH‐PTP1 TO SYNAPTIC VESICLES: A POSSIBLE ROLE IN NEUROTRANSMISSION Cell Biology International 1997, 21: 469-476. PMID: 9451803, DOI: 10.1006/cbir.1997.0185.
Life on biomembranes viewed with the atomic force microscope.Oberleithner H, Geibel J, Guggino W, Henderson R, Hunter M, Schneider S, Schwab A, Wang W. Life on biomembranes viewed with the atomic force microscope. Wiener Klinische Wochenschrift 1997, 109: 419-23. PMID: 9261980.
Localization of amiloride-sensitive sodium channels in A6 cells by atomic force microscopySmith P, Bradford A, Schneider S, Benos D, Geibel J. Localization of amiloride-sensitive sodium channels in A6 cells by atomic force microscopy American Journal Of Physiology 1997, 272: c1295-c1298. PMID: 9142855, DOI: 10.1152/ajpcell.1997.272.4.c1295.
Cyclic strain induces reorganization of integrin α5β1 and α2β1 in human umbilical vein endothelial cellsYano Y, Geibel J, Sumpio B. Cyclic strain induces reorganization of integrin α5β1 and α2β1 in human umbilical vein endothelial cells Journal Of Cellular Biochemistry 1997, 64: 505-513. PMID: 9057108, DOI: 10.1002/(sici)1097-4644(19970301)64:3<505::aid-jcb17>3.0.co;2-e.
Surface dynamics in living acinar cells imaged by atomic force microscopy: Identification of plasma membrane structures involved in exocytosisSchneider S, Sritharan K, Geibel J, Oberleithner H, Jena B. Surface dynamics in living acinar cells imaged by atomic force microscopy: Identification of plasma membrane structures involved in exocytosis Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 316-321. PMID: 8990206, PMCID: PMC19328, DOI: 10.1073/pnas.94.1.316.
Tyrosine phosphorylation of pp125FAK and paxillin in aortic endothelial cells induced by mechanical strainYano Y, Geibel J, Sumpio BE. Tyrosine phosphorylation of pp125FAK and paxillin in aortic endothelial cells induced by mechanical strain American Journal Of Physiology 1996, 271: c635-c649. PMID: 8770005, DOI: 10.1152/ajpcell.1996.271.2.c635.
An apical permeability barrier to NH3/NH4+ in isolated, perfused colonic crypts.Singh S, Binder H, Geibel J, Boron W. An apical permeability barrier to NH3/NH4+ in isolated, perfused colonic crypts. Proceedings Of The National Academy Of Sciences Of The United States Of America 1995, 92: 11573-11577. PMID: 8524806, PMCID: PMC40444, DOI: 10.1073/pnas.92.25.11573.
Fluid absorption in isolated perfused colonic crypts.Singh S, Binder H, Boron W, Geibel J. Fluid absorption in isolated perfused colonic crypts. Journal Of Clinical Investigation 1995, 96: 2373-2379. PMID: 7593625, PMCID: PMC185889, DOI: 10.1172/jci118294.
Gastrin-stimulated changes in Ca2+ concentration in parietal cells depends on adenosine 3′,5′-cyclic monophosphate levelsGeibel J, Abraham R, Modlin I, Sachs G. Gastrin-stimulated changes in Ca2+ concentration in parietal cells depends on adenosine 3′,5′-cyclic monophosphate levels Gastroenterology 1995, 109: 1060-1067. PMID: 7557070, DOI: 10.1016/0016-5085(95)90563-4.
Visualizing life on biomembranes by atomic force microscopyOberleithner H, Brinckmann E, Giebisch G, Geibel J. Visualizing life on biomembranes by atomic force microscopy Kidney International 1995, 48: 923-929. PMID: 8569101, DOI: 10.1038/ki.1995.373.
Chloride-dependent Na-H Exchange A NOVEL MECHANISM OF SODIUM TRANSPORT IN COLONIC CRYPTS*Rajendran V, Geibel J, Binder H. Chloride-dependent Na-H Exchange A NOVEL MECHANISM OF SODIUM TRANSPORT IN COLONIC CRYPTS* Journal Of Biological Chemistry 1995, 270: 11051-11054. PMID: 7744735, DOI: 10.1074/jbc.270.19.11051.
An apical permeability barrier to NH3 in isolated, perfused colonic cryptsSingh S, Geibel J, Binder H, Boron W. An apical permeability barrier to NH3 in isolated, perfused colonic crypts Gastroenterology 1995, 108: a325. DOI: 10.1016/0016-5085(95)23959-6.
Chronic hypercalcaemia disrupts membrane integrity in the gastric GLA, ND: A theory for gastric tumorogenesisAbraham R, Darr U, Geibel J. Chronic hypercalcaemia disrupts membrane integrity in the gastric GLA, ND: A theory for gastric tumorogenesis Gastroenterology 1995, 108: a43. DOI: 10.1016/0016-5085(95)22836-5.
Calcium as a marker for small bowel cell injuryDarr U, Abraham R, Geibel J. Calcium as a marker for small bowel cell injury Gastroenterology 1995, 108: a281. DOI: 10.1016/0016-5085(95)23782-8.
Unique Permeability Barrier of the Apical Surface of Parietal and Chief Cells in Isolated Perfused Gastric GlandsBoron W, Waisbren S, Modlin I, Geibel J. Unique Permeability Barrier of the Apical Surface of Parietal and Chief Cells in Isolated Perfused Gastric Glands Journal Of Experimental Biology 1994, 196: 347-360. PMID: 7823033, DOI: 10.1242/jeb.196.1.347.
Luminal perfusion of isolated gastric glandsWaisbren S, Geibel J, Boron W, Modlin I. Luminal perfusion of isolated gastric glands American Journal Of Physiology 1994, 266: c1013-c1027. PMID: 8178950, DOI: 10.1152/ajpcell.1994.266.4.c1013.
Unusual permeability properties of gastric gland cellsWaisbren S, Geibel J, Modlin I, Boron W. Unusual permeability properties of gastric gland cells Nature 1994, 368: 332-335. PMID: 8127367, DOI: 10.1038/368332a0.
Characterization of Parietal Cell Functional Morphology Utilizing Isolated Gastric Gland Perfusion, Atomic Force and Confocal MicroscopyModlin I, Waisbren S, Boron W, Soroka C, Goldenring J, Geibel J. Characterization of Parietal Cell Functional Morphology Utilizing Isolated Gastric Gland Perfusion, Atomic Force and Confocal Microscopy 1994, 329-339. DOI: 10.1007/978-3-642-79301-1_38.
Living Renal Epithelial Cells Imaged by Atomic Force MicroscopyOberleithner H, Schwab A, Wang W, Giebisch G, Hume F, Geibel J. Living Renal Epithelial Cells Imaged by Atomic Force Microscopy Nephron 1994, 66: 8-13. PMID: 8107959, DOI: 10.1159/000187759.
The Mastomys Gastric Carcinoid: Aspects of Enterochromaff in-Like Cell FunctionModlin I, Lawton G, Tang L, Geibel J, Abraham R, Darr U. The Mastomys Gastric Carcinoid: Aspects of Enterochromaff in-Like Cell Function Digestion 1994, 55: 31-37. PMID: 7535269, DOI: 10.1159/000201199.
Imaging the lamellipodium of migrating epithelial cells in vivo by atomic force microscopyOberleithner H, Giebisch G, Geibel J. Imaging the lamellipodium of migrating epithelial cells in vivo by atomic force microscopy Pflügers Archiv - European Journal Of Physiology 1993, 425: 506-510. PMID: 8134267, DOI: 10.1007/bf00374878.
Endothelin increases [Ca2+]i in M-1 mouse cortical collecting duct cells by a dual mechanismKorbmacher C, Boulpaep E, Giebisch G, Geibel J. Endothelin increases [Ca2+]i in M-1 mouse cortical collecting duct cells by a dual mechanism American Journal Of Physiology 1993, 265: c349-c357. PMID: 8368264, DOI: 10.1152/ajpcell.1993.265.2.c349.
Mechanism of apical K+ channel modulation in principal renal tubule cells. Effect of inhibition of basolateral Na(+)-K(+)-ATPase.Wang W, Geibel J, Giebisch G. Mechanism of apical K+ channel modulation in principal renal tubule cells. Effect of inhibition of basolateral Na(+)-K(+)-ATPase. The Journal Of General Physiology 1993, 101: 673-694. PMID: 8393065, PMCID: PMC2216783, DOI: 10.1085/jgp.101.5.673.
Mechanism of activation of K++ channels by minoxidil-sulfate in Madin-Darby canine kidney cellsSchwab A, Geibel J, Wang W, Oberleithner H, Giebisch G. Mechanism of activation of K++ channels by minoxidil-sulfate in Madin-Darby canine kidney cells The Journal Of Membrane Biology 1993, 132: 125-136. PMID: 8496944, DOI: 10.1007/bf00239002.
Apical H+-ATPase Activity in the Rabbit Proximal TubuleGeibel J. Apical H+-ATPase Activity in the Rabbit Proximal Tubule Cellular Physiology And Biochemistry 1993, 3: 34-41. DOI: 10.1159/000154666.
Angiotensin II stimulates both Na(+)-H+ exchange and Na+/HCO3- cotransport in the rabbit proximal tubule.Geibel J, Giebisch G, Boron W. Angiotensin II stimulates both Na(+)-H+ exchange and Na+/HCO3- cotransport in the rabbit proximal tubule. Proceedings Of The National Academy Of Sciences Of The United States Of America 1990, 87: 7917-7920. PMID: 2172967, PMCID: PMC54862, DOI: 10.1073/pnas.87.20.7917.
A potassium channel in the apical membrane of rabbit thick ascending limb of Henle's loopWang W, White S, Geibel J, Giebisch G. A potassium channel in the apical membrane of rabbit thick ascending limb of Henle's loop American Journal Of Physiology 1990, 258: f244-f253. PMID: 2309888, DOI: 10.1152/ajprenal.1990.258.2.f244.
K+ Channels of the Mammalian Collecting DuctGeibel J, Zweifach A, White S, Wang W, Giebisch G. K+ Channels of the Mammalian Collecting Duct Kidney & Blood Pressure Research 1990, 13: 59-69. PMID: 1689862, DOI: 10.1159/000173348.
Mechanism of aldosterone-induced increase of K+ conductance in early distal renal tubule cells of the frogWang W, Henderson R, Geibel J, White S, Giebisch G. Mechanism of aldosterone-induced increase of K+ conductance in early distal renal tubule cells of the frog The Journal Of Membrane Biology 1989, 111: 277-289. PMID: 2557452, DOI: 10.1007/bf01871012.
Basolateral sodium-coupled acid-base transport mechanisms of the rabbit proximal tubuleGeibel J, Giebisch G, Boron W. Basolateral sodium-coupled acid-base transport mechanisms of the rabbit proximal tubule American Journal Of Physiology 1989, 257: f790-f797. PMID: 2556038, DOI: 10.1152/ajprenal.1989.257.5.f790.
Effects of acetate on luminal acidification processes in the S3 segment of the rabbit proximal tubuleGeibel J, Giebisch G, Boron W. Effects of acetate on luminal acidification processes in the S3 segment of the rabbit proximal tubule American Journal Of Physiology 1989, 257: f586-f594. PMID: 2801961, DOI: 10.1152/ajprenal.1989.257.4.f586.
Effect of temperature on peritubular cell membrane potential and potassium conductance in isolated perfused proximal tubules of the mouseVoelkl H, Geibel J, Lang F, Greger R. Effect of temperature on peritubular cell membrane potential and potassium conductance in isolated perfused proximal tubules of the mouse Bioelectrochemistry 1987, 17: 419-427. DOI: 10.1016/0302-4598(87)80051-x.
Effects of ouabain and temperature on cell membrane potentials in isolated perfused straight proximal tubules of the mouse kidneyVölkl H, Geibel J, Greger R, Lang F. Effects of ouabain and temperature on cell membrane potentials in isolated perfused straight proximal tubules of the mouse kidney Pflügers Archiv - European Journal Of Physiology 1986, 407: 252-257. PMID: 3763371, DOI: 10.1007/bf00585299.
A microelectrode for continuous monitoring of glucose concentration in isolated perfused tubule segmentsRehwald W, Geibel J, Gstrein E, Oberleithner H. A microelectrode for continuous monitoring of glucose concentration in isolated perfused tubule segments Pflügers Archiv - European Journal Of Physiology 1984, 400: 398-402. PMID: 6462888, DOI: 10.1007/bf00587539.
A microelectrode for continuous recording of volume fluxes in isolated perfused tubule segmentsGeibel J, Völkl H, Lang F. A microelectrode for continuous recording of volume fluxes in isolated perfused tubule segments Pflügers Archiv - European Journal Of Physiology 1984, 400: 388-392. PMID: 6462886, DOI: 10.1007/bf00587537.
A microelectrode for continuous monitoring of redox activity in isolated perfused tubule segmentsVölkl H, Geibel J, Rehwald W, Lang F. A microelectrode for continuous monitoring of redox activity in isolated perfused tubule segments Pflügers Archiv - European Journal Of Physiology 1984, 400: 393-397. PMID: 6462887, DOI: 10.1007/bf00587538.
Redox microelectrodes for the continuous recording of organic substances in renal tubular fluidLang F, Gstrein E, Geibel J, Rehwald W, Völkl H, Oberleithner H. Redox microelectrodes for the continuous recording of organic substances in renal tubular fluid Bioelectrochemistry 1983, 11: 365-372. DOI: 10.1016/0302-4598(83)90033-8.
Redox microelectrodes for the continuous recording of organic substances in renal tubular fluidLang F, Gstrein E, Geibel J, Rehwald W, Völkl H, Oberleithner H. Redox microelectrodes for the continuous recording of organic substances in renal tubular fluid Journal Of Electroanalytical Chemistry 1983, 156: 365-372. DOI: 10.1016/s0022-0728(83)80688-3.

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