Jianxiong Xiao, PhD
Postdoctoral Associate
Research & Publications
Biography
Coauthors
Selected Publications
- Tumor suppressor CEBPA interacts with and inhibits DNMT3A activityChen X, Zhou W, Song R, Liu S, Wang S, Chen Y, Gao C, He C, Xiao J, Zhang L, Wang T, Liu P, Duan K, Cheng Z, Zhang C, Zhang J, Sun Y, Jackson F, Lan F, Liu Y, Xu Y, Wong J, Wang P, Yang H, Xiong Y, Chen T, Li Y, Ye D. Tumor suppressor CEBPA interacts with and inhibits DNMT3A activity. Science Advances 2022, 8: eabl5220. PMID: 35080973, PMCID: PMC8791617, DOI: 10.1126/sciadv.abl5220.
- The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombinationBeilinson HA, Glynn RA, Yadavalli AD, Xiao J, Corbett E, Saribasak H, Arya R, Miot C, Bhattacharyya A, Jones JM, Pongubala JMR, Bassing CH, Schatz DG. The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination. Journal Of Experimental Medicine 2021, 218: e20210250. PMID: 34402853, PMCID: PMC8374863, DOI: 10.1084/jem.20210250.
- The activation mechanisms of master kinases in the DNA damage responseXiao J, Rao Q, Xu Y. The activation mechanisms of master kinases in the DNA damage response. Genome Instability & Disease 2021, 2: 211-224. DOI: 10.1007/s42764-021-00045-y.
- Structural insights into the activation of ATM kinaseXiao J, Liu M, Qi Y, Chaban Y, Gao C, Pan B, Tian Y, Yu Z, Li J, Zhang P, Xu Y. Structural insights into the activation of ATM kinase. Cell Research 2019, 29: 683-685. PMID: 31320732, PMCID: PMC6796860, DOI: 10.1038/s41422-019-0205-0.
- Structural insight into autoinhibition and histone H3-induced activation of DNMT3AGuo X, Wang L, Li J, Ding Z, Xiao J, Yin X, He S, Shi P, Dong L, Li G, Tian C, Wang J, Cong Y, Xu Y. Structural insight into autoinhibition and histone H3-induced activation of DNMT3A. Nature 2014, 517: 640-644. PMID: 25383530, DOI: 10.1038/nature13899.
- Structural Insight into Coordinated Recognition of Trimethylated Histone H3 Lysine 9 (H3K9me3) by the Plant Homeodomain (PHD) and Tandem Tudor Domain (TTD) of UHRF1 (Ubiquitin-like, Containing PHD and RING Finger Domains, 1) Protein*Cheng J, Yang Y, Fang J, Xiao J, Zhu T, Chen F, Wang P, Li Z, Yang H, Xu Y. Structural Insight into Coordinated Recognition of Trimethylated Histone H3 Lysine 9 (H3K9me3) by the Plant Homeodomain (PHD) and Tandem Tudor Domain (TTD) of UHRF1 (Ubiquitin-like, Containing PHD and RING Finger Domains, 1) Protein*. Journal Of Biological Chemistry 2012, 288: 1329-1339. PMID: 23161542, PMCID: PMC3543016, DOI: 10.1074/jbc.m112.415398.