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Jennifer Buenzle Dwyer, MD, PhD

Co-Director and Co-Founder of the Pediatric Depression Clinic, Child Study Center

Research & Publications
Biography
News

Coauthors

Selected Publications

Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled TrialDwyer JB, Landeros-Weisenberger A, Johnson JA, Londono Tobon A, Flores JM, Nasir M, Couloures K, Sanacora G, Bloch MH. Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial American Journal Of Psychiatry 2021, 178: 352-362. PMID: 33653121, DOI: 10.1176/appi.ajp.2020.20010018.
Glutamate Systems in DSM-5 Anxiety Disorders: Their Role and a Review of Glutamate and GABA PsychopharmacologyNasir M, Trujillo D, Levine J, Dwyer JB, Rupp ZW, Bloch MH. Glutamate Systems in DSM-5 Anxiety Disorders: Their Role and a Review of Glutamate and GABA Psychopharmacology Frontiers In Psychiatry 2020, 11: 548505. PMID: 33329087, PMCID: PMC7710541, DOI: 10.3389/fpsyt.2020.548505.
Hormonal Treatments for Major Depressive Disorder: State of the ArtDwyer JB, Aftab A, Radhakrishnan R, Widge A, Rodriguez CI, Carpenter LL, Nemeroff CB, McDonald WM, Kalin NH. Hormonal Treatments for Major Depressive Disorder: State of the Art American Journal Of Psychiatry 2020, 177: 686-705. PMID: 32456504, PMCID: PMC7841732, DOI: 10.1176/appi.ajp.2020.19080848.
Annual Research Review: Defining and treating pediatric treatment‐resistant depressionDwyer JB, Stringaris A, Brent DA, Bloch MH. Annual Research Review: Defining and treating pediatric treatment‐resistant depression Journal Of Child Psychology And Psychiatry 2020, 61: 312-332. PMID: 32020643, PMCID: PMC8314167, DOI: 10.1111/jcpp.13202.
Prenatal nicotine sex-dependently alters adolescent dopamine system developmentDwyer JB, Cardenas A, Franke RM, Chen Y, Bai Y, Belluzzi JD, Lotfipour S, Leslie FM. Prenatal nicotine sex-dependently alters adolescent dopamine system development Translational Psychiatry 2019, 9: 304. PMID: 31740669, PMCID: PMC6861272, DOI: 10.1038/s41398-019-0640-1.
Antidepressants for Pediatric Patients.Dwyer JB, Bloch MH. Antidepressants for Pediatric Patients. Current Psychiatry 2019, 18: 26-42f. PMID: 31511767, PMCID: PMC6738970.
A Developmental Perspective of Dopaminergic Dysfunction in Tourette SyndromeDwyer JB. A Developmental Perspective of Dopaminergic Dysfunction in Tourette Syndrome Biological Psychiatry 2018, 84: e33-e35. PMID: 30115244, DOI: 10.1016/j.biopsych.2018.07.008.
Ketamine as a Treatment for Adolescent Depression: A Case ReportDwyer JB, Beyer C, Wilkinson ST, Ostroff RB, Qayyum Z, Bloch MH. Ketamine as a Treatment for Adolescent Depression: A Case Report Journal Of The American Academy Of Child & Adolescent Psychiatry 2017, 56: 352-354. PMID: 28335880, DOI: 10.1016/j.jaac.2017.01.006.
An Integrated Neuroscience Perspective on Formulation and Treatment Planning for Posttraumatic Stress Disorder: An Educational ReviewRoss DA, Arbuckle MR, Travis MJ, Dwyer JB, van Schalkwyk GI, Ressler KJ. An Integrated Neuroscience Perspective on Formulation and Treatment Planning for Posttraumatic Stress Disorder: An Educational Review JAMA Psychiatry 2017, 74: 407-415. PMID: 28273291, PMCID: PMC5504531, DOI: 10.1001/jamapsychiatry.2016.3325.
The Nature of Nurture: How Developmental Experiences Program Adult Stress CircuitryDwyer JB, Ross DA. The Nature of Nurture: How Developmental Experiences Program Adult Stress Circuitry Biological Psychiatry 2017, 81: e57-e59. PMID: 28317550, PMCID: PMC5712909, DOI: 10.1016/j.biopsych.2017.02.004.
Modern Microglia: Novel Targets in Psychiatric NeuroscienceDwyer JB, Ross DA. Modern Microglia: Novel Targets in Psychiatric Neuroscience Biological Psychiatry 2016, 80: e47-e49. PMID: 27601341, PMCID: PMC5371712, DOI: 10.1016/j.biopsych.2016.08.006.
Adolescent Maturation of Dopamine D1 and D2 Receptor Function and Interactions in RodentsDwyer JB, Leslie FM. Adolescent Maturation of Dopamine D1 and D2 Receptor Function and Interactions in Rodents PLOS ONE 2016, 11: e0146966. PMID: 26784516, PMCID: PMC4718668, DOI: 10.1371/journal.pone.0146966.
Modulation of cell adhesion systems by prenatal nicotine exposure in limbic brain regions of adolescent female ratsCao J, Dwyer JB, Mangold JE, Wang J, Wei J, Leslie FM, Li MD. Modulation of cell adhesion systems by prenatal nicotine exposure in limbic brain regions of adolescent female rats The International Journal Of Neuropsychopharmacology 2011, 14: 157-174. PMID: 20196919, PMCID: PMC5575906, DOI: 10.1017/s1461145710000179.
The dynamic effects of nicotine on the developing brainDwyer JB, McQuown SC, Leslie FM. The dynamic effects of nicotine on the developing brain Pharmacology & Therapeutics 2009, 122: 125-139. PMID: 19268688, PMCID: PMC2746456, DOI: 10.1016/j.pharmthera.2009.02.003.
Nicotine and brain developmentDwyer JB, Broide RS, Leslie FM. Nicotine and brain development Birth Defects Research Part C Embryo Today Reviews 2008, 84: 30-44. PMID: 18383130, DOI: 10.1002/bdrc.20118.

Clinical Trials

Conditions	Study Title
Mental Health & Behavioral Research	Ketamine for Adolescent Suicidality
Mental Health & Behavioral Research	Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide
Diseases of the Nervous System; Genetics - Adult; Genetics - Pediatric; Mental Health & Behavioral Research	Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)

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Research & Publications

Biography

News

Coauthors

Selected Publications

Clinical Trials