Ivan Surovtsev
Research Scientist in Cell Biology; Research Scientist, Cell Biology
Research & Publications
Biography
Coauthors
Selected Publications
- An ESCRT grommet cooperates with a diffusion barrier to maintain nuclear integrityAder N, Chen L, Surovtsev I, Chadwick W, Rodriguez E, King M, Lusk C. An ESCRT grommet cooperates with a diffusion barrier to maintain nuclear integrity. Nature Cell Biology 2023, 25: 1465-1477. PMID: 37783794, DOI: 10.1038/s41556-023-01235-4.
- Loops and the activity of loop extrusion factors constrain chromatin dynamicsBailey M, Surovtsev I, Williams J, Yan H, Yuan T, Li K, Duseau K, Mochrie S, King M. Loops and the activity of loop extrusion factors constrain chromatin dynamics. Molecular Biology Of The Cell 2023, 34: ar78. PMID: 37126401, PMCID: PMC10398873, DOI: 10.1091/mbc.e23-04-0119.
- Extrusion of chromatin loops by a composite loop extrusion factorYan H, Surovtsev I, Williams JF, Bailey MLP, King MC, Mochrie SGJ. Extrusion of chromatin loops by a composite loop extrusion factor. Physical Review E 2021, 104: 024414. PMID: 34525654, PMCID: PMC9112126, DOI: 10.1103/physreve.104.024414.
- Interconnecting solvent quality, transcription, and chromosome folding in Escherichia coliXiang Y, Surovtsev IV, Chang Y, Govers SK, Parry BR, Liu J, Jacobs-Wagner C. Interconnecting solvent quality, transcription, and chromosome folding in Escherichia coli. Cell 2021, 184: 3626-3642.e14. PMID: 34186018, DOI: 10.1016/j.cell.2021.05.037.
- Covariance distributions in single particle trackingBailey MLP, Yan H, Surovtsev I, Williams JF, King MC, Mochrie SGJ. Covariance distributions in single particle tracking. Physical Review E 2021, 103: 032405. PMID: 33862686, PMCID: PMC9115892, DOI: 10.1103/physreve.103.032405.
- Is the Bacterial Cytoplasm a Poor Solvent for the Chromosome?Xiang Y, Surovtsev I, Dufresne E, Jacobs-Wagner C. Is the Bacterial Cytoplasm a Poor Solvent for the Chromosome? Biophysical Journal 2019, 116: 320a. DOI: 10.1016/j.bpj.2018.11.1736.
- mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning CrowdingDelarue M, Brittingham G, Pfeffer S, Surovtsev I, Pinglay S, Kennedy K, Schaffer M, Gutierrez J, Sang D, Poterewicz G, Chung J, Plitzko J, Groves J, Jacobs-Wagner C, Engel B, Holt L. mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding. Cell 2018, 174: 338-349.e20. PMID: 29937223, PMCID: PMC10080728, DOI: 10.1016/j.cell.2018.05.042.
- Subcellular Organization: A Critical Feature of Bacterial Cell ReplicationSurovtsev IV, Jacobs-Wagner C. Subcellular Organization: A Critical Feature of Bacterial Cell Replication. Cell 2018, 172: 1271-1293. PMID: 29522747, PMCID: PMC5870143, DOI: 10.1016/j.cell.2018.01.014.
- Replication fork passage drives asymmetric dynamics of a critical nucleoid‐associated protein in CaulobacterArias‐Cartin R, Dobihal GS, Campos M, Surovtsev IV, Parry B, Jacobs‐Wagner C. Replication fork passage drives asymmetric dynamics of a critical nucleoid‐associated protein in Caulobacter. The EMBO Journal 2016, 36: 301-318. PMID: 28011580, PMCID: PMC5286365, DOI: 10.15252/embj.201695513.
- DNA-relay mechanism is sufficient to explain ParA-dependent intracellular transport and patterning of single and multiple cargosSurovtsev IV, Campos M, Jacobs-Wagner C. DNA-relay mechanism is sufficient to explain ParA-dependent intracellular transport and patterning of single and multiple cargos. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: e7268-e7276. PMID: 27799522, PMCID: PMC5135302, DOI: 10.1073/pnas.1616118113.
- Oufti: an integrated software package for high‐accuracy, high‐throughput quantitative microscopy analysisPaintdakhi A, Parry B, Campos M, Irnov I, Elf J, Surovtsev I, Jacobs-Wagner C. Oufti: an integrated software package for high‐accuracy, high‐throughput quantitative microscopy analysis. Molecular Microbiology 2015, 99: 767-777. PMID: 26538279, PMCID: PMC4752901, DOI: 10.1111/mmi.13264.
- A Constant Size Extension Drives Bacterial Cell Size HomeostasisCampos M, Surovtsev IV, Kato S, Paintdakhi A, Beltran B, Ebmeier SE, Jacobs-Wagner C. A Constant Size Extension Drives Bacterial Cell Size Homeostasis. Cell 2014, 159: 1433-1446. PMID: 25480302, PMCID: PMC4258233, DOI: 10.1016/j.cell.2014.11.022.
- Evidence for a DNA-relay mechanism in ParABS-mediated chromosome segregationLim HC, Surovtsev IV, Beltran BG, Huang F, Bewersdorf J, Jacobs-Wagner C. Evidence for a DNA-relay mechanism in ParABS-mediated chromosome segregation. ELife 2014, 3: e02758. PMID: 24859756, PMCID: PMC4067530, DOI: 10.7554/elife.02758.
- Cellular Metabolism Fluidizes the Glassy Bacterial CytoplasmParry B, Surovtsev I, Cabeen M, O'Hern C, Dufresne E, Jacobs-Wagner C. Cellular Metabolism Fluidizes the Glassy Bacterial Cytoplasm. Biophysical Journal 2014, 106: 313a. DOI: 10.1016/j.bpj.2013.11.1814.
- The Bacterial Cytoplasm Has Glass-like Properties and Is Fluidized by Metabolic ActivityParry BR, Surovtsev IV, Cabeen MT, O’Hern C, Dufresne ER, Jacobs-Wagner C. The Bacterial Cytoplasm Has Glass-like Properties and Is Fluidized by Metabolic Activity. Cell 2013, 156: 183-194. PMID: 24361104, PMCID: PMC3956598, DOI: 10.1016/j.cell.2013.11.028.
- Spatial organization of the flow of genetic information in bacteriaMontero Llopis P, Jackson AF, Sliusarenko O, Surovtsev I, Heinritz J, Emonet T, Jacobs-Wagner C. Spatial organization of the flow of genetic information in bacteria. Nature 2010, 466: 77-81. PMID: 20562858, PMCID: PMC2896451, DOI: 10.1038/nature09152.
- Mathematical modeling of a minimal protocell with coordinated growth and divisionSurovtsev I, Zhang Z, Lindahl P, Morgan J. Mathematical modeling of a minimal protocell with coordinated growth and division. Journal Of Theoretical Biology 2009, 260: 422-429. PMID: 19501600, DOI: 10.1016/j.jtbi.2009.06.001.
- Kinetic Modeling of the Assembly, Dynamic Steady State, and Contraction of the FtsZ Ring in Prokaryotic CytokinesisSurovtsev I, Morgan J, Lindahl P. Kinetic Modeling of the Assembly, Dynamic Steady State, and Contraction of the FtsZ Ring in Prokaryotic Cytokinesis. PLOS Computational Biology 2008, 4: e1000102. PMID: 18604268, PMCID: PMC2432035, DOI: 10.1371/journal.pcbi.1000102.
- Corrigendum to “Whole-cell modeling framework in which biochemical dynamics impact aspects of cellular geometry” [J. Theor. Biol. 244 (2007) 154–166]Surovtsev I, Morgan J, Lindahl P. Corrigendum to “Whole-cell modeling framework in which biochemical dynamics impact aspects of cellular geometry” [J. Theor. Biol. 244 (2007) 154–166]. Journal Of Theoretical Biology 2008, 251: 552. DOI: 10.1016/j.jtbi.2007.12.014.
- Nickel-Dependent Oligomerization of the Alpha Subunit of Acetyl-Coenzyme A Synthase/Carbon Monoxide Dehydrogenase †Tan X, Kagiampakis I, Surovtsev I, Demeler B, Lindahl P. Nickel-Dependent Oligomerization of the Alpha Subunit of Acetyl-Coenzyme A Synthase/Carbon Monoxide Dehydrogenase †. Biochemistry 2007, 46: 11606-11613. PMID: 17887777, PMCID: PMC2528952, DOI: 10.1021/bi7014663.
- Kinetics of CO Insertion and Acetyl Group Transfer Steps, and a Model of the Acetyl-CoA Synthase Catalytic MechanismTan X, Surovtsev I, Lindahl P. Kinetics of CO Insertion and Acetyl Group Transfer Steps, and a Model of the Acetyl-CoA Synthase Catalytic Mechanism. Journal Of The American Chemical Society 2006, 128: 12331-12338. PMID: 16967985, PMCID: PMC2527582, DOI: 10.1021/ja0627702.
- Mössbauer and EPR Study of Recombinant Acetyl-CoA Synthase from Moorella thermoacetica †Bramlett M, Stubna A, Tan X, Surovtsev I, Münck E, Lindahl P. Mössbauer and EPR Study of Recombinant Acetyl-CoA Synthase from Moorella thermoacetica †. Biochemistry 2006, 45: 8674-8685. PMID: 16834342, DOI: 10.1021/bi060003+.
- A framework for whole-cell mathematical modelingMorgan J, Surovtsev I, Lindahl P. A framework for whole-cell mathematical modeling. Journal Of Theoretical Biology 2004, 231: 581-596. PMID: 15488535, DOI: 10.1016/j.jtbi.2004.07.014.
- Laminin-binding protein as a cellular receptor for the equine Venezuelan encephalomyelitis virus: Report 2. Inhibition of replication of equine Venezuelan encephalomyelitis virus by blocking laminin-binding protein on the surface of Vero cells.Bondarenko E, Protopopova E, Konovalova S, Surovtsev I, Mal'tsev V, Loktev V. Laminin-binding protein as a cellular receptor for the equine Venezuelan encephalomyelitis virus: Report 2. Inhibition of replication of equine Venezuelan encephalomyelitis virus by blocking laminin-binding protein on the surface of Vero cells. Molecular Genetics, Microbiology And Virology 2004, 36-40. PMID: 15025003.
- Inhibition of replication of Venezuelan equine encephalomyelitis with polyclonal antibodies to laminin-binding protein.Bondarenko E, Protopopova E, Surovtsev I, Shvalov A, Loktev V. Inhibition of replication of Venezuelan equine encephalomyelitis with polyclonal antibodies to laminin-binding protein. Problems Of Virology 2004, 49: 32-7. PMID: 15529862.
- Kinetics of the initial stage of immunoagglutionation studied with the scanning flow cytometerSurovtsev I, Yurkin M, Shvalov A, Nekrasov V, Sivolobova G, Grazhdantseva A, Maltsev V, Chernyshev A. Kinetics of the initial stage of immunoagglutionation studied with the scanning flow cytometer. Colloids And Surfaces B Biointerfaces 2003, 32: 245-255. DOI: 10.1016/s0927-7765(03)00177-2.
- Kinetic study of the initial stages of agglutination process with scanning flow cytometerSurovtsev I, Yurkin M, Shvalov A, Sivolobova G. Kinetic study of the initial stages of agglutination process with scanning flow cytometer. Proceedings Of SPIE--the International Society For Optical Engineering 2003, 4962: 354-363. DOI: 10.1117/12.477906.
- Laminin-binding protein (LBP) as a cellular receptor for the virus of Venezuelan equine encephalomyelitis (VEE): Part 1. A study of the interaction between VEE virus virions and the human recombinant LBP.Bondarenko E, Protopopova E, Konovalova S, Sorokin A, Kachko A, Surovtsev I, Loktev V. Laminin-binding protein (LBP) as a cellular receptor for the virus of Venezuelan equine encephalomyelitis (VEE): Part 1. A study of the interaction between VEE virus virions and the human recombinant LBP. Molecular Genetics, Microbiology And Virology 2003, 36-9. PMID: 14664162.
- Mathematical Modeling the Kinetics of Cell Distribution in the Process of Ligand–Receptor BindingSUROVTSEV I, RAZUMOV I, NEKRASOV V, SHVALOV A, SOINI J, MALTSEV V, PETROV A, LOKTEV V, CHERNYSHEV A. Mathematical Modeling the Kinetics of Cell Distribution in the Process of Ligand–Receptor Binding. Journal Of Theoretical Biology 2000, 206: 407-417. PMID: 10988026, DOI: 10.1006/jtbi.2000.2136.
- Individual Escherichia coli cells studied from light scattering with the scanning flow cytometerShvalov A, Soini J, Surovtsev I, Kochneva G, Sivolobova G, Petrov A, Maltsev V. Individual Escherichia coli cells studied from light scattering with the scanning flow cytometer. Cytometry 2000, 41: 41-45. PMID: 10942895, DOI: 10.1002/1097-0320(20000901)41:1<41::aid-cyto6>3.0.co;2-n.
- Particle classification from light scattering with the scanning flow cytometerShvalov A, Surovtsev I, Chernyshev A, Soini J, Maltsev V. Particle classification from light scattering with the scanning flow cytometer. Cytometry 1999, 37: 215-220. PMID: 10520202, DOI: 10.1002/(sici)1097-0320(19991101)37:3<215::aid-cyto8>3.0.co;2-3.
- Kinetic study of formation of antigen-antibody complexes on the cell surface with the scanning flow cytometerSurovtsev I, Razumov I, Shvalov A. Kinetic study of formation of antigen-antibody complexes on the cell surface with the scanning flow cytometer. Proceedings Of SPIE--the International Society For Optical Engineering 1999, 3604: 199-206. DOI: 10.1117/12.349201.
- A mathematical model of dispersion radical polymerization kineticsChernyshev A, Soini A, Surovtsev I, Maltsev V, Soini E. A mathematical model of dispersion radical polymerization kinetics. Journal Of Polymer Science Part A Polymer Chemistry 1997, 35: 1799-1807. DOI: 10.1002/(sici)1099-0518(19970715)35:9<1799::aid-pola20>3.0.co;2-#.