Etienne Leveille, MD
Clinical Fellow
Research & Publications
Biography
News
Coauthors
Selected Publications
- Genetic Modeling of B-cell State Transitions for Rational Design of Lymphoma Therapies.Leveille E, Kothari S, Müschen M. Genetic Modeling of B-cell State Transitions for Rational Design of Lymphoma Therapies. Blood Cancer Discovery 2022, 4: 8-11. PMID: 36534735, PMCID: PMC9816816, DOI: 10.1158/2643-3230.bcd-22-0180.
- BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell TransformationChan L, Hurtz C, Robinson M, Leveille E, Geng H, Caeser R, Xu L, Kume K, Xiao G, Müschen M. BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell Transformation. Blood 2022, 140: 9177-9178. DOI: 10.1182/blood-2022-169946.
- A Phosphatase Membrane-Shuttle Enables Feedback Control of B-Cell SignalingLee J, Kume K, Robinson M, Sun R, Ma N, Chen Z, Xiao G, Cosgun K, Chan L, Leveille E, Klemm L, Vykunta V, Shy B, Geng H, Luger S, Litzow M, Marson A, Paietta E, Vaidehi N, Meffre E, Müschen M. A Phosphatase Membrane-Shuttle Enables Feedback Control of B-Cell Signaling. Blood 2022, 140: 1698-1699. DOI: 10.1182/blood-2022-170324.
- Divergent MYC- and BCL6-Driven Metabolic Programs Enable Dynamic Regulation of Cell Biomass in B-Cell MalignanciesKume K, Chen Z, Chan L, Robinson M, Leveille E, Lee J, Cosgun K, Arce D, Khanduja D, Klemm L, Müschen M. Divergent MYC- and BCL6-Driven Metabolic Programs Enable Dynamic Regulation of Cell Biomass in B-Cell Malignancies. Blood 2022, 140: 5900-5901. DOI: 10.1182/blood-2022-170396.
- Structural Elements of the BCR Determine Permissiveness to Oncogenic RAS-Driven B-Cell TransformationChan L, Robinson M, Cosgun K, Yu X, Leveille E, Geng H, Müschen M. Structural Elements of the BCR Determine Permissiveness to Oncogenic RAS-Driven B-Cell Transformation. Blood 2022, 140: 8758-8759. DOI: 10.1182/blood-2022-170079.
- SYK and ZAP70 kinases in autoimmunity and lymphoid malignanciesLeveille E, Chan LN, Mirza AS, Kume K, Müschen M. SYK and ZAP70 kinases in autoimmunity and lymphoid malignancies. Cellular Signalling 2022, 94: 110331. PMID: 35398488, DOI: 10.1016/j.cellsig.2022.110331.
- GCH1 mutations in hereditary spastic paraplegia.Varghaei P, Yoon G, Estiar MA, Veyron S, Leveille E, Dupré N, Trempe JF, Rouleau GA, Gan-Or Z. GCH1 mutations in hereditary spastic paraplegia. Clinical Genetics 2021, 100: 51-58. PMID: 33713342, DOI: 10.1111/cge.13955.
- Metabolic determinants of B-cell selectionChan LN, Aghania E, Leveille E, Müschen M. Metabolic determinants of B-cell selection. Biochemical Society Transactions 2021, 49: 1467-1478. PMID: 34196360, DOI: 10.1042/bst20201316.
- Genetic Events Inhibiting Apoptosis in Diffuse Large B Cell Lymphoma.Leveille E, Johnson NA. Genetic Events Inhibiting Apoptosis in Diffuse Large B Cell Lymphoma. Cancers 2021, 13 PMID: 33946435, PMCID: PMC8125500, DOI: 10.3390/cancers13092167.
- Investigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson's disease using machine learning.Ramezani M, Mouches P, Yoon E, Rajashekar D, Ruskey JA, Leveille E, Martens K, Kibreab M, Hammer T, Kathol I, Maarouf N, Sarna J, Martino D, Pfeffer G, Gan-Or Z, Forkert ND, Monchi O. Investigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson's disease using machine learning. Scientific Reports 2021, 11: 4917. PMID: 33649398, PMCID: PMC7921412, DOI: 10.1038/s41598-021-84316-4.
- Evidence for Non-Mendelian Inheritance in Spastic Paraplegia 7.Estiar MA, Yu E, Haj Salem I, Ross JP, Mufti K, Akçimen F, Leveille E, Spiegelman D, Ruskey JA, Asayesh F, Dagher A, Yoon G, Tarnopolsky M, Boycott KM, Dupre N, Dion PA, Suchowersky O, Trempe JF, Rouleau GA, Gan-Or Z. Evidence for Non-Mendelian Inheritance in Spastic Paraplegia 7. Movement Disorders : Official Journal Of The Movement Disorder Society 2021 PMID: 33598982, DOI: 10.1002/mds.28528.
- GBA variants in REM sleep behavior disorder: A multicenter study.Krohn L, Ruskey JA, Rudakou U, Leveille E, Asayesh F, Hu MTM, Arnulf I, Dauvilliers Y, Högl B, Stefani A, Monaca CC, Abril B, Plazzi G, Antelmi E, Ferini-Strambi L, Heidbreder A, Boeve BF, Espay AJ, De Cock VC, Mollenhauer B, Sixel-Döring F, Trenkwalder C, Sonka K, Kemlink D, Figorilli M, Puligheddu M, Dijkstra F, Viaene M, Oertel W, Toffoli M, Gigli GL, Valente M, Gagnon JF, Desautels A, Montplaisir JY, Postuma RB, Rouleau GA, Gan-Or Z. GBA variants in REM sleep behavior disorder: A multicenter study. Neurology 2020, 95: e1008-e1016. PMID: 32591474, PMCID: PMC7668554, DOI: 10.1212/WNL.0000000000010042.
- Analysis of DNM3 and VAMP4 as genetic modifiers of LRRK2 Parkinson’s diseaseBrown EE, Blauwendraat C, Trinh J, Rizig M, Nalls MA, Leveille E, Ruskey JA, Jonvik H, Tan MMX, Bandres-Ciga S, Hassin-Baer S, Brockmann K, Infante J, Tolosa E, Ezquerra M, Romdhan S, Benmahdjoub M, Arezki M, Mhiri C, Hardy J, Singleton AB, Alcalay RN, Gasser T, Grosset DG, Williams NM, Pittman A, Gan-Or Z, Fernandez-Santiago R, Brice A, Lesage S, Farrer M, Wood N, Morris HR, Consortium I. Analysis of DNM3 and VAMP4 as genetic modifiers of LRRK2 Parkinson’s disease. Neurobiology Of Aging 2020, 97: 148.e17-148.e24. PMID: 32873436, PMCID: PMC7762821, DOI: 10.1016/j.neurobiolaging.2020.07.002.
- Clinical Characterization of Traumatic Acute Interhemispheric Subdural Hematoma.Léveillé E, Schur S, AlAzri A, Couturier C, Maleki M, Marcoux J. Clinical Characterization of Traumatic Acute Interhemispheric Subdural Hematoma. The Canadian Journal Of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques 2020, 47: 504-510. PMID: 32122420, DOI: 10.1017/cjn.2020.44.
- Use of mobile health technologies for postoperative care in paediatric surgery: A systematic review.Nguyen N, Leveille E, Guadagno E, Kalisya LM, Poenaru D. Use of mobile health technologies for postoperative care in paediatric surgery: A systematic review. Journal Of Telemedicine And Telecare 2020, 1357633X20934682. PMID: 32605411, DOI: 10.1177/1357633X20934682.
- Clinical and genetic analysis of ATP13A2 in hereditary spastic paraplegia expands the phenotype.Estiar MA, Leveille E, Spiegelman D, Dupre N, Trempe JF, Rouleau GA, Gan-Or Z. Clinical and genetic analysis of ATP13A2 in hereditary spastic paraplegia expands the phenotype. Molecular Genetics & Genomic Medicine 2020, 8: e1052. PMID: 31944623, PMCID: PMC7057081, DOI: 10.1002/mgg3.1052.
- Association Between BDNF Val66Met Polymorphism and Mild Behavioral Impairment in Patients With Parkinson's Disease.Ramezani M, Ruskey JA, Martens K, Kibreab M, Javer Z, Kathol I, Hammer T, Cheetham J, Leveille E, Martino D, Sarna JR, Gan-Or Z, Pfeffer G, Ismail Z, Monchi O. Association Between BDNF Val66Met Polymorphism and Mild Behavioral Impairment in Patients With Parkinson's Disease. Frontiers In Neurology 2020, 11: 587992. PMID: 33584494, PMCID: PMC7874164, DOI: 10.3389/fneur.2020.587992.
- Sequencing of the GBA coactivator, Saposin C, in Parkinson disease.Ouled Amar Bencheikh B, Leveille E, Ruskey JA, Spiegelman D, Liong C, Fon EA, Rouleau GA, Dauvilliers Y, Dupre N, Alcalay RN, Gan-Or Z. Sequencing of the GBA coactivator, Saposin C, in Parkinson disease. Neurobiology Of Aging 2018, 72: 187.e1-187.e3. PMID: 30037697, PMCID: PMC6215722, DOI: 10.1016/j.neurobiolaging.2018.06.034.
- Triple A syndrome presenting as complicated hereditary spastic paraplegia.Leveille E, Gonorazky HD, Rioux MF, Hazrati LN, Ruskey JA, Carnevale A, Spiegelman D, Dionne-Laporte A, Rouleau GA, Yoon G, Gan-Or Z. Triple A syndrome presenting as complicated hereditary spastic paraplegia. Molecular Genetics & Genomic Medicine 2018, 6: 1134-1139. PMID: 30381913, PMCID: PMC6305671, DOI: 10.1002/mgg3.492.
- Association study of essential tremor genetic loci in Parkinson's disease.Ross JP, Mohtashami S, Leveille E, Johnson AM, Xiong L, Dion PA, Fon E, Dauvilliers Y, Dupré N, Rouleau GA, Gan-Or Z. Association study of essential tremor genetic loci in Parkinson's disease. Neurobiology Of Aging 2018, 66: 178.e13-178.e15. PMID: 29398123, DOI: 10.1016/j.neurobiolaging.2018.01.001.