Research & Publications
Dr. Longbrake directs the clinical and translational research program in neuroimmunology at Yale University. Her current work focuses on the relationships between the microbiome/metabolome, multiple sclerosis, and the immunomodulatory medications used to treat the disease. She is the PI for a national, investigator initiated clinical trial examining whether a short course of immunotherapy at the very earliest stages of MS can lead to sustained remission (CELLO study) and is working to decipher the earliest immune changes that occur leading up to a diagnosis of MS. Further information about Dr. Longbrake's research program can be found at her lab website.
Multiple Sclerosis; Neuromyelitis Optica; Autoimmune Diseases of the Nervous System
Public Health Interests
Genetics, Genomics, Epigenetics; Immunology; Nutrition; Microbiome