Dae Yup Han, PhD, DABR
Assistant Professor, Therapeutic Radiology
Research & Publications
Biography
Research Summary
External Beam Radiation Therapy (EBRT):
- Multi-image modalities guided radiation therapy
- 4D motion management
Brachytherapy (BT):
- Developing an advanced BT system: Applicator design and Treatment planning system
- Image-guided/Intensity-modulated brachytherapy (IGBT, IMBT)
- Intra-cavitary brachytherapy (uterine cervix, Brain, Breast, Rectum), interstitial brachytherapy (prostate), Intravascular brachytherapy (IVBT), Ocular brachytherapy (eye plaque)
Monte-Carlo Simulation, System Automation, Robotics, Machine Learning
Coauthors
Research Interests
Automation; Brachytherapy; Cardiovascular Diseases; Image Processing, Computer-Assisted; Monte Carlo Method; Radiotherapy; Radiotherapy, Computer-Assisted; Robotics; Software Design; Radiotherapy, Intensity-Modulated; Radiotherapy, Image-Guided; Machine Learning
Selected Publications
- Direction-Modulated Brachytherapy for High-Dose-Rate Treatment of Cervical Cancer. I: Theoretical DesignHan D, Webster M, Scanderbeg D, Yashar C, Choi D, Song B, Devic S, Ravi A, Song W. Direction-Modulated Brachytherapy for High-Dose-Rate Treatment of Cervical Cancer. I: Theoretical Design. International Journal Of Radiation Oncology • Biology • Physics 2014, 89: 666-673. PMID: 24751413, DOI: 10.1016/j.ijrobp.2014.02.039.
- Direction Modulated Brachytherapy for Treatment of Cervical Cancer. II: Comparative Planning Study With Intracavitary and Intracavitary–Interstitial TechniquesHan DY, Safigholi H, Soliman A, Ravi A, Leung E, Scanderbeg DJ, Liu Z, Owrangi A, Song WY. Direction Modulated Brachytherapy for Treatment of Cervical Cancer. II: Comparative Planning Study With Intracavitary and Intracavitary–Interstitial Techniques. International Journal Of Radiation Oncology • Biology • Physics 2016, 96: 440-448. PMID: 27598809, DOI: 10.1016/j.ijrobp.2016.06.015.
- Treatment Delivery Technology for BrachytherapyCunha J, Han D. Treatment Delivery Technology for Brachytherapy. 2017, 41-67. DOI: 10.1007/978-3-319-44827-5_3.
- Resection Cavity Contraction Effects in the Use of Radioactive Sources (1-25 versus Cs-131) for Intra-Operative Brain ImplantsHan D, Ma L, Braunstein S, Raleigh D, Sneed P, McDermott M, McDermott M. Resection Cavity Contraction Effects in the Use of Radioactive Sources (1-25 versus Cs-131) for Intra-Operative Brain Implants. Cureus 2018, 10: e2079. PMID: 29560292, PMCID: PMC5856410, DOI: 10.7759/cureus.2079.
- Dosimetric response of Gafchromic™ EBT‐XD film to therapeutic protonsGuan F, Wang X, Yang M, Draeger E, Han D, Iga K, Guo F, Perles L, Li Y, Sahoo N, Mohan R, Chen Z. Dosimetric response of Gafchromic™ EBT‐XD film to therapeutic protons. Precision Radiation Oncology 2023, 7: 15-26. PMID: 37868341, PMCID: PMC10586355, DOI: 10.1002/pro6.1187.
- Frequency of errors in the transfer of treatment parameters from the treatment planning system to the oncology information system in a multi‐vendor environmentDonahue W, Draeger E, Han D, Chen Z. Frequency of errors in the transfer of treatment parameters from the treatment planning system to the oncology information system in a multi‐vendor environment. Journal Of Applied Clinical Medical Physics 2022, 24: e13868. PMID: 36527239, PMCID: PMC10113690, DOI: 10.1002/acm2.13868.
- Dynamic Modulated Brachytherapy (DMBT) Balloon Applicator for Accelerated Partial Breast IrradiationGuy C, Oh S, Han D, Kim S, Arthur D, Song W. Dynamic Modulated Brachytherapy (DMBT) Balloon Applicator for Accelerated Partial Breast Irradiation. International Journal Of Radiation Oncology • Biology • Physics 2019, 104: 953-961. PMID: 30910767, DOI: 10.1016/j.ijrobp.2019.03.026.
- Optimizing beam models for dosimetric accuracy over a wide range of treatmentsChen J, Morin O, Weethee B, Perez-Andujar A, Phillips J, Held M, Kearny V, Han D, Cheung J, Chuang C, Valdes G, Sudhyadhom A, Solberg T. Optimizing beam models for dosimetric accuracy over a wide range of treatments. Physica Medica 2019, 58: 47-53. PMID: 30824149, DOI: 10.1016/j.ejmp.2019.01.011.
- Direction modulated brachytherapy (DMBT) tandem applicator for cervical cancer treatment: Choosing the optimal shielding materialSafigholi H, Han DY, Soliman A, Song WY. Direction modulated brachytherapy (DMBT) tandem applicator for cervical cancer treatment: Choosing the optimal shielding material. Medical Physics 2018, 45: 3524-3533. PMID: 29858499, DOI: 10.1002/mp.13030.
- Quantitative CT assessment of a novel direction-modulated brachytherapy tandem applicatorElzibak AH, Kager PM, Soliman A, Paudel MR, Safigholi H, Han DY, Karotki A, Ravi A, Song WY. Quantitative CT assessment of a novel direction-modulated brachytherapy tandem applicator. Brachytherapy 2017, 17: 465-475. PMID: 29174936, DOI: 10.1016/j.brachy.2017.10.006.
- Direction modulated brachytherapy (DMBT) for treatment of cervical cancer: A planning study with 192Ir, 60Co, and 169Yb HDR sourcesSafigholi H, Han DY, Mashouf S, Soliman A, Meigooni AS, Owrangi A, Song WY. Direction modulated brachytherapy (DMBT) for treatment of cervical cancer: A planning study with 192Ir, 60Co, and 169Yb HDR sources. Medical Physics 2017, 44: 6538-6547. PMID: 28940520, DOI: 10.1002/mp.12598.
- Real-time electromagnetic tracking–based treatment platform for high-dose-rate prostate brachytherapy: Clinical workflows and end-to-end validationBeaulieu L, Racine E, Han DY, Vigneault E, Hsu IC, Cunha JAM. Real-time electromagnetic tracking–based treatment platform for high-dose-rate prostate brachytherapy: Clinical workflows and end-to-end validation. Brachytherapy 2017, 17: 103-110. PMID: 28576644, DOI: 10.1016/j.brachy.2017.04.247.
- Quantitative MRI assessment of a novel direction modulated brachytherapy tandem applicator for cervical cancer at 1.5TSoliman AS, Elzibak A, Easton H, Kim JY, Han DY, Safigholi H, Mashouf S, Owrangi A, Ravi A, Song WY. Quantitative MRI assessment of a novel direction modulated brachytherapy tandem applicator for cervical cancer at 1.5T. Radiotherapy And Oncology 2016, 120: 500-506. PMID: 27443448, DOI: 10.1016/j.radonc.2016.07.006.
- Real-Time EM-Tracking Based Treatment Platform for High Dose Rate Prostate Brachytherapy: End-to-End Validation and Clinical WorkflowsBeaulieu L, Racine E, Han D, Vigneault É, Hsu I, Cunha A. Real-Time EM-Tracking Based Treatment Platform for High Dose Rate Prostate Brachytherapy: End-to-End Validation and Clinical Workflows. Brachytherapy 2016, 15: s38-s39. DOI: 10.1016/j.brachy.2016.04.039.
- HDR brachytherapy of rectal cancer using a novel grooved‐shielding applicator designWebster M, Devic S, Vuong T, Han D, Scanderbeg D, Choi D, Song B, Song W. HDR brachytherapy of rectal cancer using a novel grooved‐shielding applicator design. Medical Physics 2013, 40: 091704. PMID: 24007137, DOI: 10.1118/1.4816677.
- Dynamic modulated brachytherapy (DMBT) for rectal cancerWebster M, Devic S, Vuong T, Han D, Park J, Scanderbeg D, Lawson J, Song B, Watkins W, Pawlicki T, Song W. Dynamic modulated brachytherapy (DMBT) for rectal cancer. Medical Physics 2012, 40: 011718. PMID: 23298088, DOI: 10.1118/1.4769416.