Daniel Jacobs
Hospital Resident
Research & Publications
Biography
Coauthors
Selected Publications
- Patterns of Care for T1 Glottic Squamous Cell Carcinomas from 2004–2020Malik D, Jacobs D, Fereydooni S, Park H, Mehra S. Patterns of Care for T1 Glottic Squamous Cell Carcinomas from 2004–2020. The Laryngoscope 2024 PMID: 38411338, DOI: 10.1002/lary.31363.
- Dimeric Tubulin Modifies Mechanical Properties of Lipid Bilayer, as Probed Using Gramicidin A ChannelRostovtseva T, Weinrich M, Jacobs D, Rosencrans W, Bezrukov S. Dimeric Tubulin Modifies Mechanical Properties of Lipid Bilayer, as Probed Using Gramicidin A Channel. International Journal Of Molecular Sciences 2024, 25: 2204. PMID: 38396879, PMCID: PMC10889239, DOI: 10.3390/ijms25042204.
- Treatment, Management, and Otolaryngology Consultation for Epistaxis in the Emergency Room: An Institutional ExperienceJacobs D, Wang V, Chao J, Manes R, Lee Y. Treatment, Management, and Otolaryngology Consultation for Epistaxis in the Emergency Room: An Institutional Experience. American Journal Of Rhinology And Allergy 2023, 38: 102-107. PMID: 38155492, DOI: 10.1177/19458924231223348.
- Restricting α-synuclein transport into mitochondria by inhibition of α-synuclein–VDAC complexation as a potential therapeutic target for Parkinson’s disease treatmentRajendran M, Queralt-Martín M, Gurnev P, Rosencrans W, Rovini A, Jacobs D, Abrantes K, Hoogerheide D, Bezrukov S, Rostovtseva T. Restricting α-synuclein transport into mitochondria by inhibition of α-synuclein–VDAC complexation as a potential therapeutic target for Parkinson’s disease treatment. Cellular And Molecular Life Sciences 2022, 79: 368. PMID: 35718804, PMCID: PMC11072225, DOI: 10.1007/s00018-022-04389-w.
- ASO Visual Abstract: Merkel Cell Carcinoma—Changing Practice Patterns and Impact on Recurrence-Free and Overall Survival at a Single Institution and NationallyEsposito A, Jacobs D, Ariyan S, Galan A, Kluger H, Clune J, Weiss S, Tran T, Olino K. ASO Visual Abstract: Merkel Cell Carcinoma—Changing Practice Patterns and Impact on Recurrence-Free and Overall Survival at a Single Institution and Nationally. Annals Of Surgical Oncology 2021, 28: 736-737. DOI: 10.1245/s10434-021-10784-7.
- ASO Author Reflections: The Utility of Overall Survival as an Outcome in the Study of Merkel Cell CarcinomaEsposito AC, Jacobs D, Olino K. ASO Author Reflections: The Utility of Overall Survival as an Outcome in the Study of Merkel Cell Carcinoma. Annals Of Surgical Oncology 2021, 29: 425-426. PMID: 34523003, DOI: 10.1245/s10434-021-10791-8.
- Prolonged inpatient stay after upfront total laryngectomy is associated with overall survivalJacobs D, Kafle S, Earles J, Rahmati R, Mehra S, Judson BL. Prolonged inpatient stay after upfront total laryngectomy is associated with overall survival. Laryngoscope Investigative Otolaryngology 2021, 6: 94-102. PMID: 33614936, PMCID: PMC7883619, DOI: 10.1002/lio2.441.
- Assessment of Age, Period, and Birth Cohort Effects and Trends in Merkel Cell Carcinoma Incidence in the United StatesJacobs D, Huang H, Olino K, Weiss S, Kluger H, Judson BL, Zhang Y. Assessment of Age, Period, and Birth Cohort Effects and Trends in Merkel Cell Carcinoma Incidence in the United States. JAMA Dermatology 2021, 157: 59-65. PMID: 33146688, PMCID: PMC7643047, DOI: 10.1001/jamadermatol.2020.4102.
- Tunable Electromechanical Nanopore Trap Reveals Populations of Peripheral Membrane Protein Binding ConformationsHoogerheide D, Rostovtseva T, Jacobs D, Gurnev P, Bezrukov S. Tunable Electromechanical Nanopore Trap Reveals Populations of Peripheral Membrane Protein Binding Conformations. ACS Nano 2020, 15: 989-1001. PMID: 33369404, PMCID: PMC9019845, DOI: 10.1021/acsnano.0c07672.
- Revisiting the Radiation Therapy Oncology Group 1221 Hypothesis: Treatment for Stage III/IV HPV-Negative Oropharyngeal CancerJacobs D, Torabi SJ, Park HS, Rahmati R, Young MR, Mehra S, Judson BL. Revisiting the Radiation Therapy Oncology Group 1221 Hypothesis: Treatment for Stage III/IV HPV-Negative Oropharyngeal Cancer. Otolaryngology 2020, 164: 1240-1248. PMID: 33198564, DOI: 10.1177/0194599820969613.
- Sequencing of Sclerosing Microcystic Adenocarcinoma Identifies Mutational Burden and Somatic Variants Associated With TumorigenesisJIANG R, MARQUEZ J, TOWER JI, JACOBS D, CHEN W, MEHRA S, PRASAD ML, JUDSON BL. Sequencing of Sclerosing Microcystic Adenocarcinoma Identifies Mutational Burden and Somatic Variants Associated With Tumorigenesis. Anticancer Research 2020, 40: 6375-6379. PMID: 33109575, DOI: 10.21873/anticanres.14658.
- Primary Treatment Selection for Clinically Node-Negative Merkel Cell Carcinoma of the Head and NeckJacobs D, Olino K, Park HS, Clune J, Cheraghlou S, Girardi M, Burtness B, Kluger H, Judson BL. Primary Treatment Selection for Clinically Node-Negative Merkel Cell Carcinoma of the Head and Neck. Otolaryngology 2020, 164: 1214-1221. PMID: 33079010, DOI: 10.1177/0194599820967001.
- Assessing National Utilization Trends and Outcomes of Robotic and Endoscopic Thyroidectomy in the United StatesJacobs D, Torabi SJ, Gibson C, Rahmati R, Mehra S, Judson BL. Assessing National Utilization Trends and Outcomes of Robotic and Endoscopic Thyroidectomy in the United States. Otolaryngology 2020, 163: 947-955. PMID: 32539533, DOI: 10.1177/0194599820927699.
- Consequences of Medical Hierarchy on Medical Students, Residents, and Medical Education in OtolaryngologySalehi PP, Jacobs D, Suhail‐Sindhu T, Judson BL, Azizzadeh B, Lee YH. Consequences of Medical Hierarchy on Medical Students, Residents, and Medical Education in Otolaryngology. Otolaryngology 2020, 163: 906-914. PMID: 32482121, DOI: 10.1177/0194599820926105.
- Assessment of Lymph Node Evaluation in Patients with Clinically Node Negative Merkel Cell Carcinoma of the Head and NeckJacobs D, Park H, Young M, Olino K, Rahmati R, Mehra S, Burtness B, Judson B. Assessment of Lymph Node Evaluation in Patients with Clinically Node Negative Merkel Cell Carcinoma of the Head and Neck. International Journal Of Radiation Oncology • Biology • Physics 2020, 106: 1191-1192. DOI: 10.1016/j.ijrobp.2019.11.099.
- An Update on Trends and Disparities in Utilization of Total Laryngectomy: a Population-Based AnalysisJacobs D, Park H, Young M, Breen C, Rahmati R, Mehra S, Judson B. An Update on Trends and Disparities in Utilization of Total Laryngectomy: a Population-Based Analysis. International Journal Of Radiation Oncology • Biology • Physics 2020, 106: 1145-1146. DOI: 10.1016/j.ijrobp.2019.11.214.
- Changing Demographics of Laryngeal Cancer: Are Patients Getting Younger?Jacobs D, Park H, Rahmati R, Mehra S, Judson B. Changing Demographics of Laryngeal Cancer: Are Patients Getting Younger? International Journal Of Radiation Oncology • Biology • Physics 2020, 106: 1162-1163. DOI: 10.1016/j.ijrobp.2019.11.186.
- A lower affinity to cytosolic proteins reveals VDAC3 isoform-specific role in mitochondrial biologyQueralt-Martín M, Bergdoll L, Teijido O, Munshi N, Jacobs D, Kuszak A, Protchenko O, Reina S, Magrì A, De Pinto V, Bezrukov S, Abramson J, Rostovtseva T. A lower affinity to cytosolic proteins reveals VDAC3 isoform-specific role in mitochondrial biology. The Journal Of General Physiology 2020, 152: e201912501. PMID: 31935282, PMCID: PMC7062508, DOI: 10.1085/jgp.201912501.
- Probing Membrane Association of α-Synuclein Domains with VDAC Nanopore Reveals Unexpected Binding PatternJacobs D, Hoogerheide D, Rovini A, Jiang Z, Lee J, Rostovtseva T, Bezrukov S. Probing Membrane Association of α-Synuclein Domains with VDAC Nanopore Reveals Unexpected Binding Pattern. Scientific Reports 2019, 9: 4580. PMID: 30872688, PMCID: PMC6418135, DOI: 10.1038/s41598-019-40979-8.
- Human VDAC3 Forms VDAC1-Type Anionic Channels that are High-Conducting, Permeable to Metabolites, and Regulated by Cytosolic ProteinsQueralt-Martin M, Bergdoll L, Abramson J, Jacobs D, Hermida O, Hoogerheide D, Bezrukov S, Rostovtseva T. Human VDAC3 Forms VDAC1-Type Anionic Channels that are High-Conducting, Permeable to Metabolites, and Regulated by Cytosolic Proteins. Biophysical Journal 2019, 116: 155a. DOI: 10.1016/j.bpj.2018.11.861.
- Assessing the role of residue E73 and lipid headgroup charge in VDAC1 voltage gatingQueralt-Martín M, Bergdoll L, Jacobs D, Bezrukov S, Abramson J, Rostovtseva T. Assessing the role of residue E73 and lipid headgroup charge in VDAC1 voltage gating. Biochimica Et Biophysica Acta (BBA) - Bioenergetics 2018, 1860: 22-29. PMID: 30412693, PMCID: PMC8283775, DOI: 10.1016/j.bbabio.2018.11.001.
- Assessing the Role of Residue E73 in VDAC1 Voltage GatingQueralt-Martín M, Bergdoll L, Abramson J, Jacobs D, Bezrukov S, Rostovtseva T. Assessing the Role of Residue E73 in VDAC1 Voltage Gating. Biophysical Journal 2018, 114: 660a. DOI: 10.1016/j.bpj.2017.11.3564.
- Alpha-Synuclein-Induced Mitochondrial Dysfunction: Role of VDAC and Membrane CompositionRostovtseva T, Rovini A, Jacobs D, Hoogerheide D, Gurnev P, Bezrukov S. Alpha-Synuclein-Induced Mitochondrial Dysfunction: Role of VDAC and Membrane Composition. Biophysical Journal 2018, 114: 2a. DOI: 10.1016/j.bpj.2017.11.035.
- Model-Free Observation of Polypeptide Translocation Success Rate through a NanoporeHoogerheide D, Gurnev P, Jacobs D, Rostovtseva T, Bezrukov S. Model-Free Observation of Polypeptide Translocation Success Rate through a Nanopore. Biophysical Journal 2018, 114: 687a-688a. DOI: 10.1016/j.bpj.2017.11.3707.
- Structural features and lipid binding domain of tubulin on biomimetic mitochondrial membranesHoogerheide D, Noskov S, Jacobs D, Bergdoll L, Silin V, Worcester D, Abramson J, Nanda H, Rostovtseva T, Bezrukov S. Structural features and lipid binding domain of tubulin on biomimetic mitochondrial membranes. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 114: e3622-e3631. PMID: 28420794, PMCID: PMC5422764, DOI: 10.1073/pnas.1619806114.
- Mitochondrial VDAC as an Electromechanical Probe of Lipid-Dependent Membrane Binding of Alpha-SynucleinRostovtseva T, Jacobs D, Hoogerheide D, Rovini A, Bezrukov S. Mitochondrial VDAC as an Electromechanical Probe of Lipid-Dependent Membrane Binding of Alpha-Synuclein. Biophysical Journal 2017, 112: 440a. DOI: 10.1016/j.bpj.2016.11.2348.
- Tubulin on Biomimetic Mitochondrial Membranes: Structural Features and Lipid DiscriminationHoogerheide D, Noskov S, Jacobs D, Nanda H, Rostovtseva T, Bezrukov S. Tubulin on Biomimetic Mitochondrial Membranes: Structural Features and Lipid Discrimination. Biophysical Journal 2017, 112: 390a-391a. DOI: 10.1016/j.bpj.2016.11.2121.
- Evidence of Distinct Channel Conformations and Substrate Binding Affinities for the Mitochondrial Outer Membrane Protein Translocase Pore Tom40*Kuszak A, Jacobs D, Gurnev P, Shiota T, Louis J, Lithgow T, Bezrukov S, Rostovtseva T, Buchanan S. Evidence of Distinct Channel Conformations and Substrate Binding Affinities for the Mitochondrial Outer Membrane Protein Translocase Pore Tom40*. Journal Of Biological Chemistry 2015, 290: 26204-26217. PMID: 26336107, PMCID: PMC4646270, DOI: 10.1074/jbc.m115.642173.
- Evidence of Distinct Channel Conformations for the Mitochondrial Outer Membrane Translocase Tom40Kuszak A, Jacobs D, Gurnev P, Lithgow T, Bezrukov S, Rostovtseva T, Buchanan S. Evidence of Distinct Channel Conformations for the Mitochondrial Outer Membrane Translocase Tom40. The FASEB Journal 2015, 29 DOI: 10.1096/fasebj.29.1_supplement.777.7.
- Investigating Tom40 Structure and Function Relationship using Single Channel AnalysisJacobs D, Kuszak A, Buchanan S, Bezrukov S, Rostovtseva T, Gurnev P. Investigating Tom40 Structure and Function Relationship using Single Channel Analysis. Biophysical Journal 2014, 106: 590a. DOI: 10.1016/j.bpj.2013.11.3268.