Basmah Safdar, MD, FACEP

• Adam de Havenon
• Albert Ko
• Albert Sinusas
• Alexandra Lansky
• Arjun Venkatesh
• Caitlin Malicki
• Carlos Mena-Hurtado
• Carolyn M Mazure
• Cary Gross
• Charles Wira
• Craig Rothenberg
• Erica C Leifheit
• Erica Spatz
• Fred Sanford Gorelick
• Gail D'Onofrio
• Gary Désir
• Guido Falcone
• Harlan Krumholz
• James Dziura
• Jeffrey Testani
• Joe El-Khoury
• Judith Lichtman
• Karthik Murugiah
• Kevin Sheth
• Kim Germaine Emiel Smolderen
• Leslie Curry
• Makoto Mori
• Mary Geda
• Melissa Langhan
• Pooja Agrawal
• Rachel Dreyer
• Rajita Sinha
• Robert Soufer
• Rohan Khera
• Sam Payabvash
• Sharon Anoush Chekijian
• Sherry McKee
• Steven Schiff
• Yuan Lu
• Zhenqiu Lin

Cardiovascular Diseases; Chest Pain; Emergency Medicine; Exercise Therapy; Leadership; Women's Health; Clinical Trial; Microvascular Angina; Healthcare Disparities; Translational Research, Biomedical; Cerebral Small Vessel Diseases; COVID-19

Women's Health

• Clinical characteristics and prognosis of patients with microvascular angina: an international and prospective cohort study by the Coronary Vasomotor Disorders International Study (COVADIS) GroupShimokawa H, Suda A, Takahashi J, Berry C, Camici PG, Crea F, Escaned J, Ford T, Yii E, Kaski JC, Kiyooka T, Mehta PK, Ong P, Ozaki Y, Pepine C, Rimoldi O, Safdar B, Sechtem U, Tsujita K, Yasuda S, Beltrame JF, Merz CNB, Group O. Clinical characteristics and prognosis of patients with microvascular angina: an international and prospective cohort study by the Coronary Vasomotor Disorders International Study (COVADIS) Group. European Heart Journal 2021, 42: ehab282-. PMID: 34038937, PMCID: PMC8633728, DOI: 10.1093/eurheartj/ehab282.
• Institutional solutions addressing disparities in compensation and advancement of emergency medicine physicians: A critical appraisal of gaps and associated recommendationsMadsen TE, Heron S, Lall MD, Blomkalns A, Arbelaez C, Lopez B, Lin M, Rounds K, Sethuraman KN, Safdar B. Institutional solutions addressing disparities in compensation and advancement of emergency medicine physicians: A critical appraisal of gaps and associated recommendations. Academic Emergency Medicine 2022, 29: 710-718. PMID: 35064998, DOI: 10.1111/acem.14452.
• Effect of Physician Gender and Race on Simulated Patients’ Ratings and Confidence in Their PhysiciansSolnick RE, Peyton K, Kraft-Todd G, Safdar B. Effect of Physician Gender and Race on Simulated Patients’ Ratings and Confidence in Their Physicians. JAMA Network Open 2020, 3: e1920511. PMID: 32083686, PMCID: PMC7043197, DOI: 10.1001/jamanetworkopen.2019.20511.
• Survival of the Fittest: Impact of Cardiorespiratory Fitness on Outcomes in Men and Women with Cardiovascular DiseaseSafdar B, Mangi AA. Survival of the Fittest: Impact of Cardiorespiratory Fitness on Outcomes in Men and Women with Cardiovascular Disease. Clinical Therapeutics 2020, 42: 385-392. PMID: 32088022, DOI: 10.1016/j.clinthera.2020.01.014.
• Chapter 6 Cardiovascular disease: Sex and gender evidence in acute ischemic syndrome and heart failureSafdar B. Chapter 6 Cardiovascular disease: Sex and gender evidence in acute ischemic syndrome and heart failure. 2021, 101-127. DOI: 10.1016/b978-0-12-816569-0.00006-1.
• Patiromer utility as an adjunct treatment in patients needing urgent hyperkalaemia management (PLATINUM): design of a multicentre, randomised, double-blind, placebo-controlled, parallel-group studyRafique Z, Budden J, Quinn C, Duanmu Y, Safdar B, Bischof J, Driver B, Herzog C, Weir M, Singer A, Boone S, Soto-Ruiz K, Peacock W. Patiromer utility as an adjunct treatment in patients needing urgent hyperkalaemia management (PLATINUM): design of a multicentre, randomised, double-blind, placebo-controlled, parallel-group study. BMJ Open 2023, 13: e071311. PMID: 37308268, PMCID: PMC10277034, DOI: 10.1136/bmjopen-2022-071311.
• Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imagingde Havenon A, Parasuram N, Crawford A, Mazurek M, Chavva I, Yadlapalli V, Iglesias J, Rosen M, Falcone G, Payabvash S, Sze G, Sharma R, Schiff S, Safdar B, Wira C, Kimberly W, Sheth K. Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging. Journal Of The American Heart Association 2023, 12: e029242. PMID: 37218590, PMCID: PMC10381997, DOI: 10.1161/jaha.122.029242.
• A legacy in emergency medicine: Remembering Gloria Kuhn, DO, PhD, FACEPLall M, Sethuraman K, Agrawal P, Clem K, Madsen T, Poznanski S, Safdar B, Watts S, Choo E. A legacy in emergency medicine: Remembering Gloria Kuhn, DO, PhD, FACEP. Academic Emergency Medicine 2023 PMID: 37221923, DOI: 10.1111/acem.14753.
• Effectiveness of Monovalent mRNA COVID-19 Vaccination in Preventing COVID-19-Associated Invasive Mechanical Ventilation and Death Among Immunocompetent Adults During the Omicron Variant Period - IVY Network, 19 U.S. States, February 1, 2022-January 31, 2023.DeCuir J, Surie D, Zhu Y, Gaglani M, Ginde A, Douin D, Talbot H, Casey J, Mohr N, McNeal T, Ghamande S, Gibbs K, Files D, Hager D, Phan M, Prekker M, Gong M, Mohamed A, Johnson N, Steingrub J, Peltan I, Brown S, Martin E, Monto A, Khan A, Bender W, Duggal A, Wilson J, Qadir N, Chang S, Mallow C, Kwon J, Exline M, Lauring A, Shapiro N, Columbus C, Gottlieb R, Vaughn I, Ramesh M, Lamerato L, Safdar B, Halasa N, Chappell J, Grijalva C, Baughman A, Womack K, Rhoads J, Hart K, Swan S, Lewis N, McMorrow M, Self W. Effectiveness of Monovalent mRNA COVID-19 Vaccination in Preventing COVID-19-Associated Invasive Mechanical Ventilation and Death Among Immunocompetent Adults During the Omicron Variant Period - IVY Network, 19 U.S. States, February 1, 2022-January 31, 2023. MMWR Morbidity And Mortality Weekly Report 2023, 72: 463-468. PMID: 37104244, DOI: 10.15585/mmwr.mm7217a3.
• Renin-Angiotensin System Modulation With Synthetic Angiotensin (1-7) and Angiotensin II Type 1 Receptor–Biased Ligand in Adults With COVID-19Self W, Shotwell M, Gibbs K, de Wit M, Files D, Harkins M, Hudock K, Merck L, Moskowitz A, Apodaca K, Barksdale A, Safdar B, Javaheri A, Sturek J, Schrager H, Iovine N, Tiffany B, Douglas I, Levitt J, Busse L, Ginde A, Brown S, Hager D, Boyle K, Duggal A, Khan A, Lanspa M, Chen P, Puskarich M, Vonderhaar D, Venkateshaiah L, Gentile N, Rosenberg Y, Troendle J, Bistran-Hall A, DeClercq J, Lavieri R, Joly M, Orr M, Pulley J, Rice T, Schildcrout J, Semler M, Wang L, Bernard G, Collins S, Becker R, del Zoppo G, Henke P, Holubkov R, Johnson M, Kerr K, Lipman H, Lurie F, Pitt B, Vesely S, Fleg J, Aamodt D, Ayers J, Clark D, Collins J, Cook M, Dixon S, Graves J, Jordan C, Lindsell C, Lopez I, McKeel D, Orozco D, Prato N, Qi A, Qutab M, Stoughton C, Vermillion K, Walsh K, Winchell S, Young T, Franklin R, Wagner E, Walther T, Demitrack M, Johnson J, Walsh R, Bales B, Miller K, Torr D, Barot H, Landreth L, LaRose M, Parks L, Teixeira J, Cardenas S, Ceniceros J, Cunningham A, Kunkel S, Lovato D, Zimmerman B, Nguyen T, Zeger W, Nichols H, Wiedel N, Javaheri A, Stilinovic S, Brokowski C, Lu J, Solberg M, Lee D, Roach K, Tiffany B, Tanner C, Taylor A, Zumbahl J, Syed A, Mason J, Jackson P, Coleman R, Haughey H, Cherabuddi K, James N, Wakeman R, Duncan C, Montero C, Rogers A, Wilson J, Vojnik R, Perez C, Wyles D, Hiller T, Oakes J, Garcia A, Gong M, Mohamed A, Andrea L, Nair R, Nkemdirim W, Lopez B, Boujid S, Torres M, Garcia O, Martinez F, Baduashvili A, Bastman J, Chauhan L, Douin D, Finck L, Licursi A, ten Lohuis C, Zhang S, Bender W, Tovar S, Hayes S, Kurtzman N, Rosseto E, Scaffidi D, Shapiro N, Pak J, Allada G, Briceno G, Peña J, Oh M, Ali H, Beselman S, Eby Y, Klimov V, Hite R, Tanzeem H, Droege C, Winter J, Jackman S, Caudill A, Bayoumi E, Pascual E, Chen P, Mucha S, Thiruchelvam N, Siuba M, Mehkri O, Driver B, Hendrickson A, Kaus O, Ontiveros C, Riehm A, Laudun S, Hudock D, Ensley C, Shaner V, Gentile N, Isenberg D, Reimer H, Cincola P, Harris E, Callahan S, Yamane M, Barrios M, Desai N, Bharara A, Keller M, Majumder P, Dohe C, D’Armiento J, Goldklang M, Wagener G, Fonseca L, Valezquez-Sanchez I, Johnson N, Petersen E, Fuentes M, Newton M, Gundel S, Srinivasan V, Steel T, Robinson B. Renin-Angiotensin System Modulation With Synthetic Angiotensin (1-7) and Angiotensin II Type 1 Receptor–Biased Ligand in Adults With COVID-19. JAMA 2023, 329: 1170-1182. PMID: 37039791, PMCID: PMC10091180, DOI: 10.1001/jama.2023.3546.
• Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American Heart AssociationAlexander B, South A, August P, Bertagnolli M, Ferranti E, Grobe J, Jones E, Loria A, Safdar B, Sequeira-Lopez M, Health O. Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American Heart Association. Hypertension 2023, 80: e75-e89. PMID: 36951054, PMCID: PMC10242542, DOI: 10.1161/hyp.0000000000000227.
• Women in pediatric emergency medicine: Trends in gender from 2000 to 2020Kayani J, Reed J, Safdar B, Langhan M. Women in pediatric emergency medicine: Trends in gender from 2000 to 2020. Academic Emergency Medicine 2023, 30: 675-677. PMID: 36545838, DOI: 10.1111/acem.14644.
• Incorporating sex- and gender-based medicine into journal clubJarman AF, Safdar B, Madsen TE, Kane BG, McGregor AJ. Incorporating sex- and gender-based medicine into journal club. European Journal Of Emergency Medicine 2022, 29: 393-394. PMID: 36222813, PMCID: PMC10008087, DOI: 10.1097/mej.0000000000000973.
• A Structural Competency Framework for Emergency Medicine Research: Results from a Scoping Review and Consensus ConferenceZeidan A, Salhi B, Backster A, Shelton E, Valente A, Safdar B, Wong A, Della Porta A, Lee S, Schneberk T, Wilson J, Westgard B, Samuels-Kalow M. A Structural Competency Framework for Emergency Medicine Research: Results from a Scoping Review and Consensus Conference. Western Journal Of Emergency Medicine 2022, 23: 650-659. PMID: 36205664, PMCID: PMC9541992, DOI: 10.5811/westjem.2022.6.56056.
• Clinical Profile and Sex-Specific Recovery With Cardiac Rehabilitation After Coronary Artery Bypass Grafting SurgerySafdar B, Mori M, Nowroozpoor A, Geirsson A, D'Onofrio G, Mangi AA. Clinical Profile and Sex-Specific Recovery With Cardiac Rehabilitation After Coronary Artery Bypass Grafting Surgery. Clinical Therapeutics 2022, 44: 846-858. PMID: 35570056, DOI: 10.1016/j.clinthera.2022.04.002.
• Sex and Race Differences in the Evaluation and Treatment of Young Adults Presenting to the Emergency Department With Chest PainBanco D, Chang J, Talmor N, Wadhera P, Mukhopadhyay A, Lu X, Dong S, Lu Y, Betensky RA, Blecker S, Safdar B, Reynolds HR. Sex and Race Differences in the Evaluation and Treatment of Young Adults Presenting to the Emergency Department With Chest Pain. Journal Of The American Heart Association 2022, 11: e024199. PMID: 35506534, PMCID: PMC9238573, DOI: 10.1161/jaha.121.024199.
• Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience)Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). The American Journal Of Cardiology 2022, 173: 33-38. PMID: 35365290, PMCID: PMC9133198, DOI: 10.1016/j.amjcard.2022.03.005.
• Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experienceMurugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience. PLOS ONE 2022, 17: e0265624. PMID: 35320296, PMCID: PMC8942215, DOI: 10.1371/journal.pone.0265624.
• Association of renalase with clinical outcomes in hospitalized patients with COVID-19Safdar B, Wang M, Guo X, Cha C, Chun HJ, Deng Y, Dziura J, El-Khoury JM, Gorelick F, Ko AI, Lee AI, Safirstein R, Simonov M, Zhou B, Desir GV. Association of renalase with clinical outcomes in hospitalized patients with COVID-19. PLOS ONE 2022, 17: e0264178. PMID: 35259186, PMCID: PMC8903289, DOI: 10.1371/journal.pone.0264178.
• Influence of Sex and Gender on Lifestyle Interventions for Cardiovascular DiseaseSafdar B. Influence of Sex and Gender on Lifestyle Interventions for Cardiovascular Disease. Clinical Therapeutics 2021, 44: 8-10. PMID: 34973826, DOI: 10.1016/j.clinthera.2021.12.004.
• Corrigendum to: Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunctionNowroozpoor A, Sharp E, Gordon R, Malicki C, Hwang U, Dziura J, D'Onofrio' G, Safdar B. Corrigendum to: Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunction. European Heart Journal 2021, 43: ehab845-. PMID: 34897369, DOI: 10.1093/eurheartj/ehab845.
• Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunctionNowroozpoor A, Sharp E, Gordon R, Malicki C, Hwang U, Dziura J, D'Onofrio' G, Safdar B. Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunction. European Heart Journal 2021, 42 DOI: 10.1093/eurheartj/ehab724.2744.
• Use of peripheral arterial tonometry in detection of abnormal coronary flow reserveGaeta M, Nowroozpoor A, Dziura J, D'Onofrio G, Sinusas AJ, Safdar B. Use of peripheral arterial tonometry in detection of abnormal coronary flow reserve. Microvascular Research 2021, 138: 104223. PMID: 34256085, PMCID: PMC10227886, DOI: 10.1016/j.mvr.2021.104223.
• Sex- or Gender-specific Differences in the Clinical Presentation, Outcome, and Treatment of SARS-CoV-2Wolfe J, Safdar B, Madsen TE, Sethuraman KN, Becker B, Greenberg MR, McGregor AJ. Sex- or Gender-specific Differences in the Clinical Presentation, Outcome, and Treatment of SARS-CoV-2. Clinical Therapeutics 2021, 43: 557-571.e1. PMID: 33583576, PMCID: PMC7833665, DOI: 10.1016/j.clinthera.2021.01.015.
• Is microvascular dysfunction a systemic disorder with common biomarkers found in the heart, brain, and kidneys? — A scoping reviewNowroozpoor A, Gutterman D, Safdar B. Is microvascular dysfunction a systemic disorder with common biomarkers found in the heart, brain, and kidneys? — A scoping review. Microvascular Research 2020, 134: 104123. PMID: 33333140, DOI: 10.1016/j.mvr.2020.104123.
• National Trends in Emergency Department Care Processes for Acute Myocardial Infarction in the United States, 2005 to 2015Pendyal A, Rothenberg C, Scofi JE, Krumholz HM, Safdar B, Dreyer RP, Venkatesh AK. National Trends in Emergency Department Care Processes for Acute Myocardial Infarction in the United States, 2005 to 2015. Journal Of The American Heart Association 2020, 9: e017208. PMID: 33047624, PMCID: PMC7763391, DOI: 10.1161/jaha.120.017208.
• International prospective cohort study of microvascular angina – Rationale and designSuda A, Takahashi J, Beltrame JF, Berry C, Camici PG, Crea F, Escaned J, Ford T, Kaski J, Kiyooka T, Metha PK, Ong P, Ozaki Y, Pepine C, Rimoldi O, Safdar B, Sechtem U, Tsujita K, Yii E, Merz C, Shimokawa H, Group O. International prospective cohort study of microvascular angina – Rationale and design. IJC Heart & Vasculature 2020, 31: 100630. PMID: 32984497, PMCID: PMC7494778, DOI: 10.1016/j.ijcha.2020.100630.
• Relationship Between Depressive Symptoms and Health Status in Peripheral Artery Disease: Role of Sex DifferencesJelani Q, Mena‐Hurtado C, Burg M, Soufer R, Gosch K, Jones PG, Spertus JA, Safdar B, Smolderen KG. Relationship Between Depressive Symptoms and Health Status in Peripheral Artery Disease: Role of Sex Differences. Journal Of The American Heart Association 2020, 9: e014583. PMID: 32781883, PMCID: PMC7660812, DOI: 10.1161/jaha.119.014583.
• Unique Risks and Solutions for Equitable Advancement during the Covid-19 Pandemic: Early Experience from Frontline Physicians in Academic MedicineMadsen T, Dobiesz V, Das D, Sethuraman K, Agrawal P, Zeidan A, Goldberg E, Safdar B, Lall M. Unique Risks and Solutions for Equitable Advancement during the Covid-19 Pandemic: Early Experience from Frontline Physicians in Academic Medicine. NEJM Catalyst 2020 PMCID: PMC7380702, DOI: 10.1056/cat.20.0268.
• Cardiovascular Considerations in Caring for Pregnant Patients: A Scientific Statement From the American Heart AssociationMehta LS, Warnes CA, Bradley E, Burton T, Economy K, Mehran R, Safdar B, Sharma G, Wood M, Valente AM, Volgman A, Council O. Cardiovascular Considerations in Caring for Pregnant Patients: A Scientific Statement From the American Heart Association. Circulation 2020, 141: e884-e903. PMID: 32362133, DOI: 10.1161/cir.0000000000000772.
• Utility of discovery approach using proteomics to create a biomarker profile for coronary microvascular dysfunctionNowroozpoor A, Gutterman D, Safdar B. Utility of discovery approach using proteomics to create a biomarker profile for coronary microvascular dysfunction. Microvascular Research 2020, 129: 103985. PMID: 32007502, PMCID: PMC10291513, DOI: 10.1016/j.mvr.2020.103985.
• Diagnosis of coronary microvascular dysfunction in the clinic.Ong P, Safdar B, Seitz A, Hubert A, Beltrame J, Prescott E. Diagnosis of coronary microvascular dysfunction in the clinic. Cardiovascular Research 2020, 116: 841-855. PMID: 31904824, DOI: 10.1093/cvr/cvz339.
• Classification of Patients with Coronary Microvascular DysfunctionFodeh S, Li T, Jarad H, Safdar B. Classification of Patients with Coronary Microvascular Dysfunction. IEEE/ACM Transactions On Computational Biology And Bioinformatics 2019, 17: 704-711. PMID: 31056516, DOI: 10.1109/tcbb.2019.2914442.
• Making Promotion Count: The Gender PerspectiveMadsen TE, Heron SL, Rounds K, Kass D, Lall M, Sethuraman KN, Arbelaez C, Blomkalns A, Safdar B, Taskforce T. Making Promotion Count: The Gender Perspective. Academic Emergency Medicine 2019, 26: 335-338. PMID: 30628138, DOI: 10.1111/acem.13680.
• Inclusion of Sex and Gender in Emergency Medicine Research—A 2018 UpdateSafdar B, Ayala K, Ali SS, Seifer BJ, Hong M, Greenberg MR, Choo EK, McGregor AJ. Inclusion of Sex and Gender in Emergency Medicine Research—A 2018 Update. Academic Emergency Medicine 2019, 26: 293-302. PMID: 30637897, DOI: 10.1111/acem.13688.
• Clues to Diagnose Myocardial Infarction in the Young No Longer a Needle in the Haystack ∗Safdar B. Clues to Diagnose Myocardial Infarction in the Young No Longer a Needle in the Haystack ∗. Journal Of The American College Of Cardiology 2019, 73: 585-588. PMID: 30732712, DOI: 10.1016/j.jacc.2018.11.034.
• Elevated renalase levels in patients with acute coronary microvascular dysfunction – A possible biomarker for ischemiaSafdar B, Guo X, Johnson C, D'Onofrio G, Dziura J, Sinusas AJ, Testani J, Rao V, Desir G. Elevated renalase levels in patients with acute coronary microvascular dysfunction – A possible biomarker for ischemia. International Journal Of Cardiology 2019, 279: 155-161. PMID: 30630613, PMCID: PMC6482834, DOI: 10.1016/j.ijcard.2018.12.061.
• Identifying Patients with Coronary Microvascular Dysfunction using Machine LearningFodeh S, Li T, Jarad H, Safdar B. Identifying Patients with Coronary Microvascular Dysfunction using Machine Learning. 2018, 00: 715-721. DOI: 10.1109/icdmw.2018.00109.
• Identifying Myocardial Ischemia due to Coronary Microvascular Dysfunction in the Emergency Department: Introducing a New Paradigm in Acute Chest Pain EvaluationSafdar B, Ong P, Camici PG. Identifying Myocardial Ischemia due to Coronary Microvascular Dysfunction in the Emergency Department: Introducing a New Paradigm in Acute Chest Pain Evaluation. Clinical Therapeutics 2018, 40: 1920-1930. PMID: 30458932, DOI: 10.1016/j.clinthera.2018.09.010.
• Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO StudySafdar B, Spatz ES, Dreyer RP, Beltrame JF, Lichtman JH, Spertus JA, Reynolds HR, Geda M, Bueno H, Dziura JD, Krumholz HM, D'Onofrio G. Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study. Journal Of The American Heart Association 2018, 7: e009174. PMID: 29954744, PMCID: PMC6064896, DOI: 10.1161/jaha.118.009174.
• Prevalence and characteristics of coronary microvascular dysfunction among chest pain patients in the emergency departmentSafdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Prevalence and characteristics of coronary microvascular dysfunction among chest pain patients in the emergency department. European Heart Journal Acute Cardiovascular Care 2018, 9: 5-13. PMID: 29543037, DOI: 10.1177/2048872618764418.
• Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial InfarctionLichtman JH, Leifheit EC, Safdar B, Bao H, Krumholz HM, Lorenze NP, Daneshvar M, Spertus JA, D'Onofrio G. Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction. Circulation 2018, 137: 781-790. PMID: 29459463, PMCID: PMC5822747, DOI: 10.1161/circulationaha.117.031650.
• Current Status of Gender and Racial/Ethnic Disparities Among Academic Emergency Medicine PhysiciansMadsen TE, Linden JA, Rounds K, Hsieh Y, Lopez BL, Boatright D, Garg N, Heron SL, Jameson A, Kass D, Lall MD, Melendez AM, Scheulen JJ, Sethuraman KN, Westafer LM, Safdar B. Current Status of Gender and Racial/Ethnic Disparities Among Academic Emergency Medicine Physicians. Academic Emergency Medicine 2017, 24: 1182-1192. PMID: 28779488, DOI: 10.1111/acem.13269.
• Abstract P092: Patient Ethnicity Predicts Poor Health Access and Gaps in Perception of Personal Cardiovascular Risk FactorsKim Y, D’Onofrio G, Safdar B. Abstract P092: Patient Ethnicity Predicts Poor Health Access and Gaps in Perception of Personal Cardiovascular Risk Factors. Circulation 2017, 135 DOI: 10.1161/circ.135.suppl_1.p092.
• DOES 3-HOUR POINT OF CARE TROPONIN I PREDICT 6-HOUR POINT OF CARE TROPONIN I FOR PATIENTS IN A CHEST PAIN UNITJacob D, McNamara R, Safdar B. DOES 3-HOUR POINT OF CARE TROPONIN I PREDICT 6-HOUR POINT OF CARE TROPONIN I FOR PATIENTS IN A CHEST PAIN UNIT. Journal Of The American College Of Cardiology 2017, 69: 71. DOI: 10.1016/s0735-1097(17)33460-5.
• MECHANISMS OF ACUTE MYOCARDIAL INFARCTION IN YOUNG WOMEN AND DISCHARGE MEDICATION PATTERNSSciria C, Dreyer R, Safdar B, D'Onofrio G, Krumholz H, Spatz E. MECHANISMS OF ACUTE MYOCARDIAL INFARCTION IN YOUNG WOMEN AND DISCHARGE MEDICATION PATTERNS. Journal Of The American College Of Cardiology 2017, 69: 195. DOI: 10.1016/s0735-1097(17)33584-2.
• Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled TrialSafdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial. Clinical Therapeutics 2017, 39: 55-63. PMID: 28081848, PMCID: PMC10345862, DOI: 10.1016/j.clinthera.2016.12.002.
• Patient Experience Must Move Beyond Bad Apples.Hamedani A, Safdar B, Aaronson E, Lee TH. Patient Experience Must Move Beyond Bad Apples. Annals Of Internal Medicine 2016, 165: 869-870. PMID: 27750283, DOI: 10.7326/m16-1725.
• MICROVASCULAR ANGINA IN THE ABSENCE OF CORONARY ARTERY DISEASE IS COMMON IN UNDIFFERENTIATED CHEST PAIN PATIENTS IN THE EMERGENCY DEPARTMENTSafdar B, D’Onofrio G, Dziura J, Russell R, Naftilan M, Johnson C, Sinusas A. MICROVASCULAR ANGINA IN THE ABSENCE OF CORONARY ARTERY DISEASE IS COMMON IN UNDIFFERENTIATED CHEST PAIN PATIENTS IN THE EMERGENCY DEPARTMENT. Journal Of The American College Of Cardiology 2016, 67: 1824. DOI: 10.1016/s0735-1097(16)31825-3.
• DEPRESSION AND ANXIETY ARE ASSOCIATED WITH HIGH RATES OF RECURRENT CHEST PAINKim Y, Soffler M, Paradise S, Naftilan M, Jelani Q, Dziura J, Sinha R, Safdar B. DEPRESSION AND ANXIETY ARE ASSOCIATED WITH HIGH RATES OF RECURRENT CHEST PAIN. Journal Of The American College Of Cardiology 2016, 67: 581. DOI: 10.1016/s0735-1097(16)30582-4.
• It’s not all Chest Pain: Sex and Gender in Acute Care CardiologySoffler M, McGregor A, Safdar B. It’s not all Chest Pain: Sex and Gender in Acute Care Cardiology. 2016, 6-23. DOI: 10.1017/cbo9781107705944.004.
• Microvascular Dysfunction as Opposed to Conduit Artery Disease Explains Sex-specific Chest Pain in Emergency Department Patients With Low to Moderate Cardiac RiskSafdar B, Ali A, D’Onofrio G, Katz SD. Microvascular Dysfunction as Opposed to Conduit Artery Disease Explains Sex-specific Chest Pain in Emergency Department Patients With Low to Moderate Cardiac Risk. Clinical Therapeutics 2016, 38: 240-255.e1. PMID: 26778090, DOI: 10.1016/j.clinthera.2015.12.010.
• Abstract 308: Predictors of Depression Recognition and Site Variability in Depression Recognition in Young AMI SurvivorsSmolderen K, Spertus J, Gosch K, Dreyer R, D'Onofrio G, Lichtman J, Geda M, Beltrame J, Safdar B, Krumholz H. Abstract 308: Predictors of Depression Recognition and Site Variability in Depression Recognition in Young AMI Survivors. Circulation Cardiovascular Quality And Outcomes 2015, 8 DOI: 10.1161/circoutcomes.8.suppl_2.308.
• Sex Differences in Reperfusion in Young Patients With ST-Segment–Elevation Myocardial InfarctionD'Onofrio G, Safdar B, Lichtman JH, Strait KM, Dreyer RP, Geda M, Spertus JA, Krumholz HM. Sex Differences in Reperfusion in Young Patients With ST-Segment–Elevation Myocardial Infarction. Circulation 2015, 131: 1324-1332. PMID: 25792558, PMCID: PMC4652789, DOI: 10.1161/circulationaha.114.012293.
• Differential Survival for Men and Women from Out‐of‐hospital Cardiac Arrest Varies by Age: Results from the OPALS StudySafdar B, Stolz U, Stiell IG, Cone DC, Bobrow BJ, deBoehr M, Dreyer J, Maloney J, Spaite DW. Differential Survival for Men and Women from Out‐of‐hospital Cardiac Arrest Varies by Age: Results from the OPALS Study. Academic Emergency Medicine 2014, 21: 1503-1511. PMID: 25491713, DOI: 10.1111/acem.12540.
• Organization, Execution and Evaluation of the 2014 Academic Emergency Medicine Consensus Conference on Gender‐Specific Research in Emergency Care – An Executive SummarySafdar B, Greenberg MR. Organization, Execution and Evaluation of the 2014 Academic Emergency Medicine Consensus Conference on Gender‐Specific Research in Emergency Care – An Executive Summary. Academic Emergency Medicine 2014, 21: 1307-1317. PMID: 25420469, PMCID: PMC4340245, DOI: 10.1111/acem.12530.
• Gender‐specific Research for Emergency Diagnosis and Management of Ischemic Heart Disease: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Research WorkgroupSafdar B, Nagurney JT, Anise A, DeVon HA, D'Onofrio G, Hess EP, Hollander JE, Legato MJ, McGregor AJ, Scott J, Tewelde S, Diercks DB. Gender‐specific Research for Emergency Diagnosis and Management of Ischemic Heart Disease: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Research Workgroup. Academic Emergency Medicine 2014, 21: 1350-1360. PMID: 25413468, PMCID: PMC6402042, DOI: 10.1111/acem.12527.
• Funding Mechanisms for Gender‐specific Research: Proceedings from a Panel Discussion at the 2014 Academic Emergency Medicine Consensus ConferenceSafdar B, Greenberg MR, Anise A, Brown J, Conwit R, Filart R, Scott J, Choo EK. Funding Mechanisms for Gender‐specific Research: Proceedings from a Panel Discussion at the 2014 Academic Emergency Medicine Consensus Conference. Academic Emergency Medicine 2014, 21: 1329-1333. PMID: 25413301, PMCID: PMC4278745, DOI: 10.1111/acem.12522.
• Abstract 138: Characterizing Depressed Symptoms in Younger Women and Men Who Experienced an Acute Myocardial Infarction: Insights from the VIRGO StudySmolderen K, Strait K, Rachel D, D’Onofrio G, Zhou S, Lichtman J, Safdar B, Krumholz H, Spertus J. Abstract 138: Characterizing Depressed Symptoms in Younger Women and Men Who Experienced an Acute Myocardial Infarction: Insights from the VIRGO Study. Circulation Cardiovascular Quality And Outcomes 2014, 7 DOI: 10.1161/circoutcomes.7.suppl_1.138.
• Abstract 139: A Novel Taxonomy for Acute Myocardial Infarction in Young WomenSpatz E, Curry L, Gross C, Masoudi F, Dryer R, Bueno H, Lampropulos J, Chaudhry S, Zhou S, D'Onofrio G, Spertus J, Safdar B, Lansky A, Krumholz H. Abstract 139: A Novel Taxonomy for Acute Myocardial Infarction in Young Women. Circulation Cardiovascular Quality And Outcomes 2014, 7 DOI: 10.1161/circoutcomes.7.suppl_1.139.
• Elevated CK-MB with a Normal Troponin Does Not Predict 30-Day Adverse Cardiac Events in Emergency Department Chest Pain Observation Unit PatientsSafdar B, Bezek SK, Sinusas AJ, Russell RR, Klein MR, Dziura JD, D’onofrio G. Elevated CK-MB with a Normal Troponin Does Not Predict 30-Day Adverse Cardiac Events in Emergency Department Chest Pain Observation Unit Patients. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2014, 13: 14-19. PMID: 24526146, DOI: 10.1097/hpc.0000000000000001.
• Gender‐specific Emergency Care: Part OneMcGregor A, Davenport M, Miner J, Siegel T, Safdar B. Gender‐specific Emergency Care: Part One. Academic Emergency Medicine 2013, 20: 1181-1181. DOI: 10.1111/acem.12242.
• Gender‐specific Emergency Medicine Research: Overview and OpportunitiesMcGregor A, Safdar B, Greenberg M, Choo E. Gender‐specific Emergency Medicine Research: Overview and Opportunities. Academic Emergency Medicine 2013, 20: 1180-1180. DOI: 10.1111/acem.12239.
• Focusing a Gender Lens on Emergency Medicine Research: 2012 UpdateMcGregor AJ, Greenberg M, Safdar B, Seigel T, Hendrickson R, Poznanski S, Davenport M, Miner J, Choo EK. Focusing a Gender Lens on Emergency Medicine Research: 2012 Update. Academic Emergency Medicine 2013, 20: 313-320. PMID: 23517266, DOI: 10.1111/acem.12085.
• Incremental Value of Objective Cardiac Testing in Addition to Physician Impression and Serial Contemporary Troponin Measurements in WomenDiercks DB, Mumma BE, Peacock W, Hollander JE, Safdar B, Mahler SA, Miller CD, Counselman FL, Birkhahn R, Schrock J, Singer AJ, Nagurney JT. Incremental Value of Objective Cardiac Testing in Addition to Physician Impression and Serial Contemporary Troponin Measurements in Women. Academic Emergency Medicine 2013, 20: 265-270. PMID: 23517258, PMCID: PMC3725334, DOI: 10.1111/acem.12092.
• Sex and the CT: An Evolving Story of the HeartSafdar B, Lichtman JH, D'Onofrio G. Sex and the CT: An Evolving Story of the Heart. Academic Emergency Medicine 2012, 19: 197-200. PMID: 22320371, DOI: 10.1111/j.1553-2712.2011.01288.x.
• Diagnostic accuracy of a point-of-care troponin I assay for acute myocardial infarction within 3 hours after presentation in early presenters to the emergency department with chest painDiercks DB, Peacock WF, Hollander JE, Singer AJ, Birkhahn R, Shapiro N, Glynn T, Nowack R, Safdar B, Miller CD, Lewandrowski E, Nagurney JT. Diagnostic accuracy of a point-of-care troponin I assay for acute myocardial infarction within 3 hours after presentation in early presenters to the emergency department with chest pain. American Heart Journal 2012, 163: 74-80.e4. PMID: 22172439, DOI: 10.1016/j.ahj.2011.09.028.
• Myeloperoxidase in the diagnosis of acute coronary syndromes: The importance of spectrumPeacock WF, Nagurney J, Birkhahn R, Singer A, Shapiro N, Hollander J, Glynn T, Nowak R, Safdar B, Miller C, Peberdy M, Counselman F, Chandra A, Kosowsky J, Neuenschwander J, Schrock J, Plantholt S, Lewandrowski E, Wong V, Kupfer K, Diercks D. Myeloperoxidase in the diagnosis of acute coronary syndromes: The importance of spectrum. American Heart Journal 2011, 162: 893-899. PMID: 22093206, DOI: 10.1016/j.ahj.2011.08.017.
• Inclusion of Gender in Emergency Medicine ResearchSafdar B, McGregor AJ, McKee SA, Ali A, Radulescu R, Himelfarb NT, Klein MR, Mazure CM. Inclusion of Gender in Emergency Medicine Research. Academic Emergency Medicine 2011, 18: e1-e4. PMID: 21314767, DOI: 10.1111/j.1553-2712.2010.00978.x.
• Depression as Modifiable Coronary Risk Factor in the Emergency Department Chest Pain Observation UnitSafdar B, Foody JM, D'Onofrio G. Depression as Modifiable Coronary Risk Factor in the Emergency Department Chest Pain Observation Unit. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2010, 9: 82-87. PMID: 20520215, DOI: 10.1097/hpc.0b013e3181db06ef.
• Physician Race/Ethnicity Predicts Successful Emergency Department AnalgesiaHeins A, Homel P, Safdar B, Todd K. Physician Race/Ethnicity Predicts Successful Emergency Department Analgesia. Journal Of Pain 2010, 11: 692-697. PMID: 20382572, DOI: 10.1016/j.jpain.2009.10.017.
• Physician ethnicity predicts successful ED analgesiaHeins A, Homel P, Safdar B, Todd K. Physician ethnicity predicts successful ED analgesia. Journal Of Pain 2009, 10: s34. DOI: 10.1016/j.jpain.2009.01.145.
• Improvements in Time to ReperfusionRao V, Safdar B, Parkosewich J, Lee LV, D'Onofrio G, Foody JM. Improvements in Time to Reperfusion. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2009, 8: 38-42. PMID: 19258837, DOI: 10.1097/hpc.0b013e318194e443.
• Impact of Physician and Patient Gender on Pain Management in the Emergency Department—A Multicenter StudySafdar B, Heins A, Homel P, Miner J, Neighbor M, DeSandre P, Todd KH. Impact of Physician and Patient Gender on Pain Management in the Emergency Department—A Multicenter Study. Pain Medicine 2009, 10: 364-372. PMID: 18992042, DOI: 10.1111/j.1526-4637.2008.00524.x.
• 242: Sex Differences in Patient- and Emergency Physician-Perceived Risk of Heart Disease in an Emergency Department Chest Pain CenterSafdar B, Hogan K, Chekijian S, D'Onofrio G. 242: Sex Differences in Patient- and Emergency Physician-Perceived Risk of Heart Disease in an Emergency Department Chest Pain Center. Annals Of Emergency Medicine 2008, 52: s116. DOI: 10.1016/j.annemergmed.2008.06.260.
• Depression is a Common Coronary Risk Factor in Women Admitted to an ED Chest Pain CenterSafdar B, Foody J, D'Onofrio G. Depression is a Common Coronary Risk Factor in Women Admitted to an ED Chest Pain Center. Academic Emergency Medicine 2007, 14: s131-s131. DOI: 10.1197/j.aem.2007.03.1069.
• 375 A Multi-Faceted Community-Based Educational Program Promotes Cardiovascular Health in Women: 5 Year AnalysisSafdar B, Parkosewich J, Freed L, Foody J, Tandon S, Jubanyik K, Lin Z, D’Onofrio G. 375 A Multi-Faceted Community-Based Educational Program Promotes Cardiovascular Health in Women: 5 Year Analysis. Annals Of Emergency Medicine 2006, 48: 112-113. DOI: 10.1016/j.annemergmed.2006.07.841.
• 405 Impact of Patient Gender on Pain Management Practices in the Emergency Department: A Multi-Center StudySafdar B, Choiniere M, Crandall C, Ducharme J, Fosnocht D, Homel P, Tanabe P, Todd K. 405 Impact of Patient Gender on Pain Management Practices in the Emergency Department: A Multi-Center Study. Annals Of Emergency Medicine 2006, 48: 121. DOI: 10.1016/j.annemergmed.2006.07.874.
• Prospective Randomized Controlled Trial comparing Efficacy and Adverse events of Intravenous Ketorolac and Parenteral morphine alone and in combination in the treatment of acute renal colic.Safdar B, Degutis L, Landry K et al. (2006). Prospective Randomized Controlled Trial comparing Efficacy and Adverse events of Intravenous Ketorolac and Parenteral morphine alone and in combination in the treatment of acute renal colic. Annals of Emergency Medicine. 2006; 48(2):173-181.
• S UBCUTANEOUS E PINEPHRINE IN THE P REHOSPITAL S ETTINGSafdar B, Cone D, Pham K. S UBCUTANEOUS E PINEPHRINE IN THE P REHOSPITAL S ETTING. Prehospital Emergency Care 2001, 5: 200-207. PMID: 11339733, DOI: 10.1080/10903120190940137.
• The antiplatelet aggregatory activity of Acacia nilotica is due to blockade of calcium influx through membrane calcium channelsShah B, Safdar B, Virani S, Nawaz Z, Saeed S, Gilani A. The antiplatelet aggregatory activity of Acacia nilotica is due to blockade of calcium influx through membrane calcium channels. Vascular Pharmacology 1997, 29: 251-255. PMID: 9251908, DOI: 10.1016/s0306-3623(96)00413-2.