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Avlin Imaeda, MD, PhD

Associate Professor of Medicine (Digestive Diseases)

Contact Information

Avlin Imaeda, MD, PhD

Mailing Address

  • Yale School of Medicine

    Department of Medicine (Digestive Diseases), PO Box 208019

    New Haven, CT 06520-8019

    United States

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Research Summary

The majority of my time is spent in clinical activities, teaching and running the fellowship program. Thus, my research interests are focused mainly on quality improvement projects with fellows and clinical projects with residents interested in applying for GI fellowship. Past projects have included examining patient preferences for colon cancer screening modality in collaboration with Liana Fraenkel MD, Department of Medicine, Rheumatology, examining the location of angioectasias within the small bowel using capsule endoscopy, and looking at outcomes for different modes of endoscopic treatment of angioectasias in patients with significant GI bleeding. Additionally, I have collaborated in the past with Dr. Pichamol Jirapinyo Pichamol Jirapinyo and Christopher Thompson MD, Brigham and Women's Hospital, Harvard, on a project looking at the use of a part-task endoscopy simulator in endoscopy training. The simulator was developed by Drs Jirapinyo and Thompson and we participated in a randomized control trial of its use in first year fellows among other studies. Past quality improvement projects have included identifying a mechanism to effectively notify patients of their lab and imaging results within 2 weeks at our VA GI clinic and testing a mechanism to calculate fellow adenoma detection rates. Currently I am doing a retrospective evaluation of the impact of high resolution white light endoscopy as well as newer iterations of endoscopes on detection rates of sessile serrated adenomas.

Speciailzed Terms: Obscure GI bleeding; Endoscopy simulation in training; Quality improvement in fellowship training

Extensive Research Description

1) Localization of angioectasias within the small bowel using capsule endoscopy.

2) Outcomes of treating small bowel angioectasias with double balloon enteroscopy, push enteroscopy vs long-acting octreotide.

3) Use of a part-task endoscopic simulator in training of Gastroenterology Fellows

4) Impact of high resolution white light endoscopy and newer iterations of Olympus endoscopes on detection rates of sessile serrated adenomas.

Coauthors

Research Interests

Digestive System Diseases; Education, Medical; Gastrointestinal Hemorrhage; Patient Simulation; Quality Improvement

Selected Publications

  • S2861 New Onset Ascites, Abdominal Pain, and Eosinophilia in a Patient Treated With Nivolumab for Poorly Differentiated Lung AdenocarcinomaHundt M, Ogurick A, Imaeda A. S2861 New Onset Ascites, Abdominal Pain, and Eosinophilia in a Patient Treated With Nivolumab for Poorly Differentiated Lung Adenocarcinoma The American Journal Of Gastroenterology 2020, 115: s1499-s1499. DOI: 10.14309/01.ajg.0000713492.40655.27.
  • Mo1484 Endoscopic Ultrasound (EUS) Is Superior to Esophagogastroduodenoscopy (EGD) and Esophageal Capsule Endoscopy (ECE) for Varices ScreeningAbdi T, Marino D, Imaeda A, Chung C, Protiva P, Nagar A. Mo1484 Endoscopic Ultrasound (EUS) Is Superior to Esophagogastroduodenoscopy (EGD) and Esophageal Capsule Endoscopy (ECE) for Varices Screening Gastrointestinal Endoscopy 2015, 81: ab437. DOI: 10.1016/j.gie.2015.03.814.
  • Sa1032 Endoscopic Part-Task Simulator Training Improves Endoscopic Performance in Gastroenterology FellowsJirapinyo P, Kumar N, Tintara S, Bing V, Aihara H, Perencevich M, Lee L, Imaeda A, Thompson C. Sa1032 Endoscopic Part-Task Simulator Training Improves Endoscopic Performance in Gastroenterology Fellows Gastroenterology 2015, 148: s-202. DOI: 10.1016/s0016-5085(15)30673-9.
  • Interim Analysis of the Effectiveness of the Endoscopy Core Curriculum in Gastroenterology Fellowship Training ProgramsJirapinyo P, Imaeda A, Thompson C. Interim Analysis of the Effectiveness of the Endoscopy Core Curriculum in Gastroenterology Fellowship Training Programs The American Journal Of Gastroenterology 2014, 109: s593. DOI: 10.14309/00000434-201410002-02004.
  • Tu1070 Evaluation of an Endoscopic Simulator With Comparison to the Mayo Colonoscopy Skills Assessment ToolJirapinyo P, Bing V, Kumar N, Imaeda A, Thompson C. Tu1070 Evaluation of an Endoscopic Simulator With Comparison to the Mayo Colonoscopy Skills Assessment Tool Gastroenterology 2014, 146: s-744. DOI: 10.1016/s0016-5085(14)62692-5.
  • Sa1609 Outcomes for Endoscopic Management of Overt GI Bleeding From Small Bowel AngioectasiaPlotkin E, Larson K, Imaeda A. Sa1609 Outcomes for Endoscopic Management of Overt GI Bleeding From Small Bowel Angioectasia Gastrointestinal Endoscopy 2013, 77: ab266-ab267. DOI: 10.1016/j.gie.2013.03.660.
  • Cell Death and FibrogenesisMehal1 W, Imaeda1 A. Cell Death and Fibrogenesis Seminars In Liver Disease 2010, 30: 226-231. PMID: 20665375, PMCID: PMC3219753, DOI: 10.1055/s-0030-1255352.
  • What Is Most Important to Patients when Deciding about Colorectal Screening?Imaeda A, Bender D, Fraenkel L. What Is Most Important to Patients when Deciding about Colorectal Screening? Journal Of General Internal Medicine 2010, 25: 688-693. PMID: 20309740, PMCID: PMC2881957, DOI: 10.1007/s11606-010-1318-9.
  • Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasomeImaeda AB, Watanabe A, Sohail MA, Mahmood S, Mohamadnejad M, Sutterwala FS, Flavell RA, Mehal WZ. Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome Journal Of Clinical Investigation 2009, 119: 305-314. PMID: 19164858, PMCID: PMC2631294, DOI: 10.1172/jci35958.
  • 467 Aspirin Blocks Acetaminophen Induced Hepatotoxicity and Mortality in Mice - Dependent On the ASC/Caspase-1 InflammasomeImaeda A, Sutterwala F, Watanabe A, Mahmood S, Sohail M, Flavell R, Mehal W. 467 Aspirin Blocks Acetaminophen Induced Hepatotoxicity and Mortality in Mice - Dependent On the ASC/Caspase-1 Inflammasome Gastroenterology 2008, 134: a-767. DOI: 10.1016/s0016-5085(08)63581-7.
  • A pilot project examining the predicted preferences of patients and physicians in the primary prophylaxis of variceal hemorrhageLongacre AV, Imaeda A, Garcia‐Tsao G, Fraenkel L. A pilot project examining the predicted preferences of patients and physicians in the primary prophylaxis of variceal hemorrhage Hepatology 2007, 47: 169-176. PMID: 17935182, PMCID: PMC2674014, DOI: 10.1002/hep.21945.
  • Textbook of HepatologyRodes, J., Benhamou, J-P., Blei, A., Reichen, J., Rizzetto, M. ed Textbook of Hepatology. Blackwell Publishing (2007). “Chap 2.7.3 Antibody Production and Transport in the Liver.” Imaeda, A, Mehal, W. pp325-332.
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