Arun Chavan
Associate Research Scientist
Research & Publications
Biography
Coauthors
Selected Publications
- Tissue Biology: In Search of a New ParadigmAdler M, Chavan A, Medzhitov R. Tissue Biology: In Search of a New Paradigm. Annual Review Of Cell And Developmental Biology 2023, 39: 67-89. PMID: 37607470, DOI: 10.1146/annurev-cellbio-120420-113830.
- Maternal respiratory SARS-CoV-2 infection in pregnancy is associated with a robust inflammatory response at the maternal-fetal interfaceLu-Culligan A, Chavan AR, Vijayakumar P, Irshaid L, Courchaine EM, Milano KM, Tang Z, Pope SD, Song E, Vogels CBF, Lu-Culligan WJ, Campbell KH, Casanovas-Massana A, Bermejo S, Toothaker JM, Lee HJ, Liu F, Schulz W, Fournier J, Muenker MC, Moore AJ, Team Y, Konnikova L, Neugebauer KM, Ring A, Grubaugh ND, Ko AI, Morotti R, Guller S, Kliman HJ, Iwasaki A, Farhadian SF. Maternal respiratory SARS-CoV-2 infection in pregnancy is associated with a robust inflammatory response at the maternal-fetal interface. Med 2021, 2: 591-610.e10. PMID: 33969332, PMCID: PMC8084634, DOI: 10.1016/j.medj.2021.04.016.
- Evolution of Embryo Implantation Was Enabled by the Origin of Decidual Stromal Cells in Eutherian MammalsChavan AR, Griffith OW, Stadtmauer D, Maziarz J, Pavlicev M, Fishman R, Koren L, Romero R, Wagner GP. Evolution of Embryo Implantation Was Enabled by the Origin of Decidual Stromal Cells in Eutherian Mammals. Molecular Biology And Evolution 2020, 38: 1060-1074. PMID: 33185661, PMCID: PMC7947829, DOI: 10.1093/molbev/msaa274.
- Endometrial recognition of pregnancy occurs in the grey short-tailed opossum ( Monodelphis domestica).Griffith OW, Chavan AR, Pavlicev M, Protopapas S, Callahan R, Maziarz J, Wagner GP. Endometrial recognition of pregnancy occurs in the grey short-tailed opossum ( Monodelphis domestica). Proceedings Of The Royal Society B 2019, 286: 20190691. PMID: 31213185, PMCID: PMC6599997, DOI: 10.1098/rspb.2019.0691.
- The mammalian decidual cell evolved from a cellular stress responseErkenbrack EM, Maziarz JD, Griffith OW, Liang C, Chavan AR, Nnamani MC, Wagner GP. The mammalian decidual cell evolved from a cellular stress response. PLOS Biology 2018, 16: e2005594. PMID: 30142145, PMCID: PMC6108454, DOI: 10.1371/journal.pbio.2005594.
- The uterine decidual stromal cell: A stabilized stress response?Wagner G, Erkenbrack E, Maziarz J, Chavan A. The uterine decidual stromal cell: A stabilized stress response? Journal Of Reproductive Immunology 2018, 128: 48. DOI: 10.1016/j.jri.2018.06.023.
- Genetic Associations With Gestational Duration and Spontaneous Preterm BirthZhang G, Feenstra B, Bacelis J, Liu X, Muglia L, Juodakis J, Miller D, Litterman N, Jiang P, Russell L, Hinds D, Hu Y, Weirauch M, Chen X, Chavan A, Wagner G, Pavliev M, Nnamani M, Maziarz J, Karjalainen M, Ramet M, Sengpiel V, Geller F, Boyd H, Palotie A, Momany A, Bedell B, Ryckman K, Huusko J, Forney C, Kottyan L, Hallman M, Teramo K, Nohr E, Smith G, Melbye M, Jacobsson B, Muglia L. Genetic Associations With Gestational Duration and Spontaneous Preterm Birth. Obstetrical & Gynecological Survey 2018, 73: 83-85. DOI: 10.1097/01.ogx.0000530434.15441.45.
- Reply to Liu: Inflammation before implantation both in evolution and developmentGriffith OW, Chavan AR, Protopapas S, Maziarz J, Romero R, Wagner GP. Reply to Liu: Inflammation before implantation both in evolution and development. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 115: e3-e4. PMID: 29233940, PMCID: PMC5776823, DOI: 10.1073/pnas.1717001115.
- Genetic Associations with Gestational Duration and Spontaneous Preterm BirthZhang G, Feenstra B, Bacelis J, Liu X, Muglia LM, Juodakis J, Miller DE, Litterman N, Jiang PP, Russell L, Hinds DA, Hu Y, Weirauch MT, Chen X, Chavan AR, Wagner GP, Pavličev M, Nnamani MC, Maziarz J, Karjalainen MK, Rämet M, Sengpiel V, Geller D, Boyd HA, Palotie A, Momany A, Bedell B, Ryckman KK, Huusko JM, Forney CR, Kottyan LC, Hallman M, Teramo K, Nohr EA, Davey-Smith G, Melbye M, Jacobsson B, Muglia LJ. Genetic Associations with Gestational Duration and Spontaneous Preterm Birth. New England Journal Of Medicine 2017, 377: 1156-1167. PMID: 28877031, PMCID: PMC5561422, DOI: 10.1056/nejmoa1612665.
- The inflammation paradox in the evolution of mammalian pregnancy: turning a foe into a friendChavan AR, Griffith OW, Wagner GP. The inflammation paradox in the evolution of mammalian pregnancy: turning a foe into a friend. Current Opinion In Genetics & Development 2017, 47: 24-32. PMID: 28850905, DOI: 10.1016/j.gde.2017.08.004.
- Embryo implantation evolved from an ancestral inflammatory attachment reactionGriffith OW, Chavan AR, Protopapas S, Maziarz J, Romero R, Wagner GP. Embryo implantation evolved from an ancestral inflammatory attachment reaction. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 114: e6566-e6575. PMID: 28747528, PMCID: PMC5559003, DOI: 10.1073/pnas.1701129114.
- Evolution of Gene Expression in the Uterine Cervix related to Steroid Signaling: Conserved features in the regulation of cervical ripeningWagner GP, Nnamani MC, Chavan AR, Maziarz J, Protopapas S, Condon J, Romero R. Evolution of Gene Expression in the Uterine Cervix related to Steroid Signaling: Conserved features in the regulation of cervical ripening. Scientific Reports 2017, 7: 4439. PMID: 28667298, PMCID: PMC5493687, DOI: 10.1038/s41598-017-04759-6.
- Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interfacePavličev M, Wagner GP, Chavan AR, Owens K, Maziarz J, Dunn-Fletcher C, Kallapur SG, Muglia L, Jones H. Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface. Genome Research 2017, 27: 349-361. PMID: 28174237, PMCID: PMC5340963, DOI: 10.1101/gr.207597.116.
- Utero-placental cell interactions revealed by single cell transcriptomicsPavlicev M, Jones H, Owens K, Chavan A, Wagner G, Muglia L. Utero-placental cell interactions revealed by single cell transcriptomics. Placenta 2016, 45: 64. DOI: 10.1016/j.placenta.2016.06.015.
- The Transcriptomic Evolution of Mammalian Pregnancy: Gene Expression Innovations in Endometrial Stromal FibroblastsKin K, Maziarz J, Chavan AR, Kamat M, Vasudevan S, Birt A, Emera D, Lynch VJ, Ott TL, Pavlicev M, Wagner GP. The Transcriptomic Evolution of Mammalian Pregnancy: Gene Expression Innovations in Endometrial Stromal Fibroblasts. Genome Biology And Evolution 2016, 8: 2459-2473. PMID: 27401177, PMCID: PMC5010902, DOI: 10.1093/gbe/evw168.
- The fetal-maternal interface of the nine-banded armadillo: endothelial cells of maternal sinus are partially replaced by trophoblastChavan AR, Wagner GP. The fetal-maternal interface of the nine-banded armadillo: endothelial cells of maternal sinus are partially replaced by trophoblast. Zoological Letters 2016, 2: 11. PMID: 27284459, PMCID: PMC4899922, DOI: 10.1186/s40851-016-0048-1.
- What was the ancestral function of decidual stromal cells? A model for the evolution of eutherian pregnancyChavan AR, Bhullar BA, Wagner GP. What was the ancestral function of decidual stromal cells? A model for the evolution of eutherian pregnancy. Placenta 2016, 40: 40-51. PMID: 27016782, DOI: 10.1016/j.placenta.2016.02.012.
- Polygenic cis-regulatory adaptation in the evolution of yeast pathogenicityFraser H, Levy S, Chavan A, Shah H, Perez J, Zhou Y, Siegal M, Sinha H. Polygenic cis-regulatory adaptation in the evolution of yeast pathogenicity. Genome Research 2012, 22: 1930-1939. PMID: 22645260, PMCID: PMC3460188, DOI: 10.1101/gr.134080.111.