Anish Sharda, MD, MPH
Assistant Professor
Research & Publications
Biography
News
Research Summary
Coauthors
Selected Publications
- Insights into platelet pharmacology from a cryo-EM structure of the ABCC4 transporterSharda A, Gu S, Hwa J. Insights into platelet pharmacology from a cryo-EM structure of the ABCC4 transporter. Nature Cardiovascular Research 2023, 2: 606-608. PMID: 37655224, PMCID: PMC10470688, DOI: 10.1038/s44161-023-00293-z.
- Aspirin thromboprophylaxis in joint replacement surgery.Sharda AV, Fatovic K, Bauer KA. Aspirin thromboprophylaxis in joint replacement surgery. Res Pract Thromb Haemost 2022, 6: e12649. PMID: 35106432, DOI: 10.1002/rth2.12649.
- Circulating Protein Disulfide Isomerase Is Associated with Increased Risk of Thrombosis in JAK2-Mutated Myeloproliferative Neoplasms.Sharda AV, Bogue T, Barr A, Mendez LM, Flaumenhaft R, Zwicker JI. Circulating Protein Disulfide Isomerase Is Associated with Increased Risk of Thrombosis in JAK2-Mutated Myeloproliferative Neoplasms. Clin Cancer Res 2021, 27: 5708-5717. PMID: 34400417, DOI: 10.1158/1078-0432.CCR-21-1140.
- Anti-thrombotic effects mediated by dihydromyricetin involve both platelet inhibition and endothelial protection.Chen S, Lv K, Sharda A, Deng J, Zeng W, Zhang C, Hu Q, Jin P, Yao G, Xu X, Ming Z, Fang C. Anti-thrombotic effects mediated by dihydromyricetin involve both platelet inhibition and endothelial protection. Pharmacol Res 2021, 167: 105540. PMID: 33711433, DOI: 10.1016/j.phrs.2021.105540.
- VWF maturation and release are controlled by 2 regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2.Sharda AV, Barr AM, Harrison JA, Wilkie AR, Fang C, Mendez LM, Ghiran IC, Italiano JE, Flaumenhaft R. VWF maturation and release are controlled by 2 regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2. Blood 2020, 136: 2824-2837. PMID: 32614949, DOI: 10.1182/blood.2020005300.
- Dose-adjusted enoxaparin thromboprophylaxis in hospitalized cancer patients: a randomized, double-blinded multicenter phase 2 trial.Zwicker JI, Roopkumar J, Puligandla M, Schlechter BL, Sharda AV, Peereboom D, Joyce R, Bockorny B, Neuberg D, Bauer KA, Khorana AA. Dose-adjusted enoxaparin thromboprophylaxis in hospitalized cancer patients: a randomized, double-blinded multicenter phase 2 trial. Blood Adv 2020, 4: 2254-2260. PMID: 32442298, DOI: 10.1182/bloodadvances.2020001804.
- Platelet SecretionRobert Flaumenhaft, Anish Sharda, 19 - Platelet Secretion, Editor(s): Alan D. Michelson, Platelets (Fourth Edition), Academic Press, 2019, Pages 349-370, ISBN 9780128134566,
- Regulatory role of thiol isomerases in thrombus formation.Sharda A, Furie B. Regulatory role of thiol isomerases in thrombus formation. Expert Rev Hematol 2018, 11: 437-448. PMID: 29542339, DOI: 10.1080/17474086.2018.1452612.
- The life cycle of platelet granules.Sharda A, Flaumenhaft R. The life cycle of platelet granules. F1000Res 2018, 7: 236. PMID: 29560259, DOI: 10.12688/f1000research.13283.1.
- Detection of membrane-bound and soluble antigens by magnetic levitation.Andersen MS, Howard E, Lu S, Richard M, Gregory M, Ogembo G, Mazor O, Gorelik P, Shapiro NI, Sharda AV, Ghiran I. Detection of membrane-bound and soluble antigens by magnetic levitation. Lab Chip 2017, 17: 3462-3473. PMID: 28905952, DOI: 10.1039/c7lc00402h.
- Thrombophilia and Thrombocytopenia in the Pregnant WomanMendez, L.M., Sharda, A.V., Zwicker, J.I. (2017). Thrombophilia and Thrombocytopenia in the Pregnant Woman. In: Bernstein, C., Takoudes, T. (eds) Medical Problems During Pregnancy. Springer, Cham.
- Detection and quantification of subtle changes in red blood cell density using a cell phone.Felton EJ, Velasquez A, Lu S, Murphy RO, ElKhal A, Mazor O, Gorelik P, Sharda A, Ghiran IC. Detection and quantification of subtle changes in red blood cell density using a cell phone. Lab Chip 2016, 16: 3286-95. PMID: 27431921, DOI: 10.1039/c6lc00415f.
- Extracellular Thiol Isomerases and Their Role in Thrombus Formation.Schulman S, Bendapudi P, Sharda A, Chen V, Bellido-Martin L, Jasuja R, Furie BC, Flaumenhaft R, Furie B. Extracellular Thiol Isomerases and Their Role in Thrombus Formation. Antioxid Redox Signal 2016, 24: 1-15. PMID: 26467859, DOI: 10.1089/ars.2015.6530.
- Anticoagulation Drugs: Indications, Therapeutic Monitoring, and AntidotesSharda, A.V., Zwicker, J.I. (2016). Anticoagulation Drugs: Indications, Therapeutic Monitoring, and Antidotes. In: Abutalib, S., Connors, J., Ragni, M. (eds) Nonmalignant Hematology. Springer, Cham.
- Quercetin-3-rutinoside Inhibits Protein Disulfide Isomerase by Binding to Its b'x Domain.Lin L, Gopal S, Sharda A, Passam F, Bowley SR, Stopa J, Xue G, Yuan C, Furie BC, Flaumenhaft R, Huang M, Furie B. Quercetin-3-rutinoside Inhibits Protein Disulfide Isomerase by Binding to Its b'x Domain. J Biol Chem 2015, 290: 23543-52. PMID: 26240139, DOI: 10.1074/jbc.M115.666180.
- Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome.Sharda A, Kim SH, Jasuja R, Gopal S, Flaumenhaft R, Furie BC, Furie B. Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome. Blood 2015, 125: 1633-42. PMID: 25593336, DOI: 10.1182/blood-2014-08-597419.
- Rare Hereditary Coagulation Factor AbnormalitiesBauer K and Sharda AV. Rare Hereditary Coagulation Factor Abnormalities. In: Orkin SH Nathan DG, Ginsburg D, Look AT, Fisher DE, Lux S, IV, editors. Nathan & Oski’s
- Measurement of shear-activated platelet aggregate formation in non-anticoagulated blood: utility in detection of clopidogrel-aspirin-induced platelet dysfunction.Johnson GJ, Sharda AV, Rao GH, Ereth MH, Laxson DD, Owen WG. Measurement of shear-activated platelet aggregate formation in non-anticoagulated blood: utility in detection of clopidogrel-aspirin-induced platelet dysfunction. Clin Appl Thromb Hemost 2012, 18: 140-9. PMID: 22009986, DOI: 10.1177/1076029611423387.