2024
Unveiling the Structure in Mental Disorder Presentations
Spiller T, Duek O, Helmer M, Murray J, Fielstein E, Pietrzak R, von Känel R, Harpaz-Rotem I. Unveiling the Structure in Mental Disorder Presentations. JAMA Psychiatry 2024, 81: 1101-1107. PMID: 39110437, PMCID: PMC11307158, DOI: 10.1001/jamapsychiatry.2024.2047.Peer-Reviewed Original ResearchSymptom combinationsNational Institute of Mental Health Data ArchivePosttraumatic stress disorderDiagnostic criteriaHeterogeneity of symptomsSecondary data analysisCross-sectional studyRevision of diagnostic criteriaSymptom-based definitionsDSM criteriaStress disorderSymptom heterogeneityDisorder presentationsClinical populationsMain OutcomesAssess symptomsGroup of individualsParticipantsSymptomsNational InstituteDisordersIndividualsSchizophreniaAnxietyIndividual frequenciesAssociation patterns of antisocial personality disorder across substance use disorders
Low A, Stiltner B, Nunez Y, Adhikari K, Deak J, Pietrzak R, Kranzler H, Gelernter J, Polimanti R. Association patterns of antisocial personality disorder across substance use disorders. Translational Psychiatry 2024, 14: 346. PMID: 39198385, PMCID: PMC11358160, DOI: 10.1038/s41398-024-03054-z.Peer-Reviewed Original ResearchConceptsAntisocial personality disorderSubstance use disordersPersonality disorderUse disorderAssociation of antisocial personality disorderPresence of antisocial personality disorderPrevalence of antisocial personality disorderHazardous useDSM-5 SUD diagnosesSubstance use disorder severityDiagnostic criteriaInteraction effects with sexTobacco use disorderDSM-5Association of alcoholSUD diagnosisDisordersCocaineRacial/ethnic backgroundsIndividualsCocUDSeverityCannabisAssociation patternsAssociationW35 Nicotine Use and Metabotropic Glutamate Receptor 5 (mGluR5) in Individuals With Major Depressive and Post Traumatic Stress Disorders
Baldassarri S, Asch R, Hillmer A, Pietrzak R, DellaGioia N, Esterlis I, Davis M. W35 Nicotine Use and Metabotropic Glutamate Receptor 5 (mGluR5) in Individuals With Major Depressive and Post Traumatic Stress Disorders. Drug And Alcohol Dependence 2024, 260: 110653. DOI: 10.1016/j.drugalcdep.2023.110653.Peer-Reviewed Original Research
2020
Positive Age Beliefs Lead to Lower Dementia Risk Even Among Older Persons With High-Risk Gene
Levy B, Slade M, Pietrzak R, Ferrucci L. Positive Age Beliefs Lead to Lower Dementia Risk Even Among Older Persons With High-Risk Gene. Innovation In Aging 2020, 4: 597-597. PMCID: PMC7742059, DOI: 10.1093/geroni/igaa057.2009.Peer-Reviewed Original ResearchOlder individualsLower dementia riskStrong risk factorRetirement Study participantsHigh-risk genesΕ4 variantDementia riskRisk factorsΕ4 carriersAPOE ε4High riskDementiaOlder personsStudy participantsAPOE geneProtective factorsRelevant covariatesRiskTotal sampleBaselineCurrent studyCohortΕ4Individuals
2015
How does social support enhance resilience in the trauma-exposed individual?
Sippel L, Pietrzak R, Charney D, Mayes L, Southwick S. How does social support enhance resilience in the trauma-exposed individual? Ecology And Society 2015, 20 DOI: 10.5751/es-07832-200410.Peer-Reviewed Original Research