Robert Kalyesubula, MBChB
Cards
About
Research
Publications
2024
The Future of Kidney Care in Low and Middle-Income Countries: Challenges, Triumphs and Opportunities.
Kalyesubula R, Aklilu A, Calice-Silva V, Kumar V, Kansiime G. The Future of Kidney Care in Low and Middle-Income Countries: Challenges, Triumphs and Opportunities. Kidney360 2024 PMID: 38922683, DOI: 10.34067/kid.0000000000000489.Peer-Reviewed Original ResearchKidney careMiddle-income countriesHealth system infrastructureResilient health care systemHealth care providersKidney healthHealth care systemChronic kidney diseaseCare providersUnique risk factorsHealth priorityCare systemLack of awarenessChronic diseasesGeneral populationCareLMICsKidney replacement therapyHealthRisk factorsGenetic predispositionEarly detectionMultidisciplinary followFinancing mechanismsHuman resourcesDistribution of the ACE Gene Polymorphisms in Type 2 Diabetes Mellitus Patients, Their Associations with Nephropathy Biomarkers and Metabolic Indicators at a Tertiary Hospital in Uganda
Kiconco R, Kalyesubula R, Kiwanuka G. Distribution of the ACE Gene Polymorphisms in Type 2 Diabetes Mellitus Patients, Their Associations with Nephropathy Biomarkers and Metabolic Indicators at a Tertiary Hospital in Uganda. Diabetes Metabolic Syndrome And Obesity 2024, 17: 2211-2220. PMID: 38854447, PMCID: PMC11162639, DOI: 10.2147/dmso.s462740.Peer-Reviewed Original ResearchSerum glucose levelsType 2 diabetes mellitus patientsType 2 diabetic patientsIncreased serum glucose levelsDecreased serum glucose levelsGlycated hemoglobinGlucose levelsGene polymorphismsNephropathy biomarkersTriglyceride levelsMellitus patientsDD genotypeMetabolic indicatorsAdult type 2 diabetes mellitus patientsPeripheral blood genomic DNAMbarara Regional Referral HospitalACE II genotypeACE gene polymorphismACE DD genotypeBlood genomic DNAMultivariate logistic regressionRegional Referral HospitalACE ID genotypeSerum creatinineReferral hospitalAirway microbiome signature accurately discriminates Mycobacterium tuberculosis infection status
Kayongo A, Ntayi M, Olweny G, Kyalo E, Ndawula J, Ssengooba W, Kigozi E, Kalyesubula R, Munana R, Namaganda J, Caroline M, Sekibira R, Bagaya B, Kateete D, Joloba M, Jjingo D, Sande O, Mayanja-Kizza H. Airway microbiome signature accurately discriminates Mycobacterium tuberculosis infection status. IScience 2024, 27: 110142. PMID: 38904070, PMCID: PMC11187240, DOI: 10.1016/j.isci.2024.110142.Peer-Reviewed Original ResearchImmune responseQuantiferon-gold assayMicrobiome signaturesLonger treatment durationTuberculosis infection statusInfection statusDeadly infectious agentsQuantiferon GoldDrug toxicityActive TBLatent TBTreatment durationTherapeutic strategiesPredicting disease susceptibilityFollow-up phaseAirwayMicrobiome diversityInfectious agentsRural UgandaControl TBMycobacterium tuberculosisDisease susceptibilityCohortTuberculosisGeneXpertCapacity for the management of kidney failure in the International Society of Nephrology Africa region: report from the 2023 ISN Global Kidney Atlas (ISN-GKHA)
Tannor E, Davidson B, Nlandu Y, Bagasha P, Bilchut W, Davids M, Diongole H, Ekrikpo U, Hafiz E, Ibrahim K, Kalyesubula R, Nalado A, Olanrewaju T, Onu U, Pereira-Kamath N, Sakajiki A, Salah M, Vincent L, Arruebo S, Bello A, Caskey F, Damster S, Donner J, Jha V, Johnson D, Levin A, Malik C, Nangaku M, Okpechi I, Tonelli M, Ye F, Ashuntantang G, Arogundade F, Authors R, Gawad M, Abderrahim E, Akl A, Amekoudi E, Amouzegar A, Awobusuyi J, Bakoush O, Chissico E, Cho Y, Coker J, Cullis B, Dahwa R, Darwish R, Davison S, Divyaveer S, Ethier I, Fagoonee K, Fofana A, Freercks R, Fung W, Gandzali-Ngabe P, Ghimire A, Gouda Z, Habyarimana O, Htay H, Wan D, Irish G, Ismail W, Jagne A, Jarraya F, Jindal K, Kabllo B, Kalebi A, Folefack F, Kelly D, Lalji R, Lomatayo B, Mah S, Abderraman G, McCulloch M, Mengistu Y, Moloi M, Mwaba C, Neuen B, Ngigi J, Niang A, Nyandwi J, Odeh E, Osman M, Le Grand Ouanekpone C, Petrova A, Ranivoharisoa E, Riaz P, Saad S, See E, Sokwala A, Solarin A, Sozio S, Houssani T, Kiswaya E, Tia W, Tiv S, Ts'enoli T, Tungsanga S, Ulasi I, Vanglist S, Viecelli A, Wadee S, Wainstein M, Wearne N, Yeung E, Zaidi D. Capacity for the management of kidney failure in the International Society of Nephrology Africa region: report from the 2023 ISN Global Kidney Atlas (ISN-GKHA). Kidney International Supplements 2024, 13: 12-28. PMID: 38618494, PMCID: PMC11010621, DOI: 10.1016/j.kisu.2024.01.002.Peer-Reviewed Original ResearchHealth care workforceManagement of peopleCare workforceHealth systemKidney careWorld Health Organization building blocksIncreased out-of-pocket costsChronic kidney disease preventionGlobal Kidney Health AtlasBurden of chronic kidney diseaseOut-of-pocket costsKidney disease preventionHealth information dataHealth care workersChronic kidney diseaseManagement of kidney failureCare deliveryKidney disease managementNondialysis chronic kidney diseaseCare workersCare financingHealth infrastructureDisease preventionService deliveryKidney diseaseWCN24-758 RECOGNITION OF LOCAL INVESTIGATORS IN AUTHORSHIP OF COLLABORATIVE KIDNEY RESEARCH CONDUCTED IN LOW- AND LOWERMIDDLE INCOME COUNTRIES
Wijewickrama E, Chanchlani R, Wong M, Kumar V, Karam S, Chen T, Erikpo U, Tannor E, Calice-Silva V, Anandh U, Bajpai D, Hafidz M, Tian A, Opare-Addo P, Edeki I, Kalyesubula R. WCN24-758 RECOGNITION OF LOCAL INVESTIGATORS IN AUTHORSHIP OF COLLABORATIVE KIDNEY RESEARCH CONDUCTED IN LOW- AND LOWERMIDDLE INCOME COUNTRIES. Kidney International Reports 2024, 9: s55. DOI: 10.1016/j.ekir.2024.02.119.Peer-Reviewed Original ResearchHypertension Related Co-Morbidities and Complications in Women of Sub-Saharan Africa: A Brief Review
Hahka T, Slotkowski R, Akbar A, VanOrmer M, Sembajwe L, Ssekandi A, Namaganda A, Muwonge H, Kasolo J, Nakimuli A, Mwesigwa N, Ishimwe J, Kalyesubula R, Kirabo A, Berry A, Patel K. Hypertension Related Co-Morbidities and Complications in Women of Sub-Saharan Africa: A Brief Review. Circulation Research 2024, 134: 459-473. PMID: 38359096, PMCID: PMC10885774, DOI: 10.1161/circresaha.123.324077.Peer-Reviewed Original ResearchConceptsHypertensive disorders of pregnancyIncidence of hypertensive disorders of pregnancyCo-morbiditiesCardiovascular diseaseDisorders of pregnancyAwareness of hypertensionIndividual quality of lifeLong-term consequences of hypertensionRates of hypertensionPeripheral arterial diseaseLack of prevention programsQuality of lifeHypertensive disordersConsequences of hypertensionLives of womenDecrease morbidityTreatment strategiesUncontrolled hypertensionArtery diseaseKidney diseaseHypertensionPrevention programsKnowledge of causesHeart diseasePrevention strategiesSingle-sample measured glomerular filtration rate in Malawi, South Africa, and Uganda
Currin S, George J, Hansen C, Naicker S, Tomlinson L, Crampin A, Kalyesubula R, Newton R, Nakanga W, Nitsch D, Fabian J. Single-sample measured glomerular filtration rate in Malawi, South Africa, and Uganda. Kidney International 2024, 105: 882-885. PMID: 38307202, DOI: 10.1016/j.kint.2024.01.020.Peer-Reviewed Original ResearchChallenges to Implementing Environmentally Sustainable Kidney Care in LMICs: An Opinion Piece
Bajpai D, Hailu W, Bagasha P, Chika O, Hafiz E, Tannor E, Wijewickrama E, Kalyesubula R, Karam S, Calice-Silva V, Ethier I, Sandal S. Challenges to Implementing Environmentally Sustainable Kidney Care in LMICs: An Opinion Piece. Canadian Journal Of Kidney Health And Disease 2024, 11: 20543581241246835. PMID: 38774488, PMCID: PMC11107313, DOI: 10.1177/20543581241246835.Peer-Reviewed Original Research
2023
Self-care and healthcare seeking practices among patients with hypertension and diabetes in rural Uganda
Tusubira A, Ssinabulya I, Kalyesubula R, Nalwadda C, Akiteng A, Ngaruiya C, Rabin T, Katahoire A, Armstrong-Hough M, Hsieh E, Hawley N, Schwartz J. Self-care and healthcare seeking practices among patients with hypertension and diabetes in rural Uganda. PLOS Global Public Health 2023, 3: e0001777. PMID: 38079386, PMCID: PMC10712841, DOI: 10.1371/journal.pgph.0001777.Peer-Reviewed Original ResearchDesign Research to Embed mHealth into a Community-Led Blood Pressure Management System in Uganda: Protocol for a Mixed Methods Study
Schwab J, Wachinger J, Munana R, Nabiryo M, Sekitoleko I, Cazier J, Ingenhoff R, Favaretti C, Pillai V, Weswa I, Wafula J, Emmrich J, Bärnighausen T, Knauf F, Knauss S, Nalwadda C, Sudharsanan N, Kalyesubula R, McMahon S. Design Research to Embed mHealth into a Community-Led Blood Pressure Management System in Uganda: Protocol for a Mixed Methods Study. JMIR Research Protocols 2023, 12: e46614. PMID: 38032702, PMCID: PMC10722357, DOI: 10.2196/46614.Peer-Reviewed Original ResearchINTERNATIONAL REGISTERED REPORT IDENTIFIERIntervention prototypeManagement of hypertensionHealth careChronic disease managementMixed-methods studyMobile health interventionsResource-constrained settingsHealth system challengesUncontrolled hypertensionAntihypertensive medicationsGerman RegistryHypertension managementRisk factorsClinical trialsCardiovascular diseaseHypertensionMethods studyBasic health careMedicationsHealth interventionsConcurrent trialsSuch diseasesDisease managementPrivate facilities