María Lara-Tejero, DVM, PhD
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About
Titles
Associate Professor
Biography
Dr. Lara-Tejero received her DVM from University Complutense in Madrid, Spain in 1995, and a PhD in Microbiology from Yale University in 2001, receiving the Nat L. Sternberg Prize for outstanding PhD Thesis in the field of prokaryotic biology. She pursued postdoctoral training in Immunobiology at Memorial Sloan Kettering Institute in New York City as an Irvington Fellow. She joined the Yale University School of Medicine in 2004, where she is currently and Associate Professor of Microbial Pathogenesis. Her laboratory focuses on the study of the pathogenesis of Salmonella enterica. More specifically, her laboratory employs multidisciplinary approaches to study type III secretion machines, which deliver bacterial effector proteins into target host cells to induce pathogenicity.
Appointments
Microbial Pathogenesis
Associate Professor on TermPrimary
Other Departments & Organizations
Education & Training
- Postdoctoral training
- MSKCC (2004)
- PhD
- Yale University (2001)
- DVM
- Complutense University of Madrid (1995)
Research
Overview
Medical Subject Headings (MeSH)
Academic Achievements and Community Involvement
Links & Media
Media
Salmonella Typhimurium SPI-1-encoded type III secretion system
(A) Surface view of the 3D reconstruction of the single-particle cryo-EM map of the needle complex (NC) substructure with the atomic structures of the different NC components docked. OR1, outer ring 1; OR2, outer ring 2; IR1, inner ring 1; IR2, inner ring 2. (B) Central section of an overall cryo-ET structure of the complete injectisome in situ. Of note is the location of IR2 in the cytosolic side of the bacterial envelope. IM, inner membrane; OM, outer membrane. (C) Molecular model of the organization of the injectisome in situ, with available atomic structures fitted into the model.