Tissue engineered vascular grafts are resistant to the formation of dystrophic calcification
Turner M, Blum K, Watanabe T, Schwarz E, Nabavinia M, Leland J, Villarreal D, Schwartzman W, Chou T, Baker P, Matsumura G, Krishnamurthy R, Yates A, Hor K, Humphrey J, Marsden A, Stacy M, Shinoka T, Breuer C. Tissue engineered vascular grafts are resistant to the formation of dystrophic calcification. Nature Communications 2024, 15: 2187. PMID: 38467617, PMCID: PMC10928115, DOI: 10.1038/s41467-024-46431-4.Peer-Reviewed Original ResearchConceptsTissue-engineered vascular graftsTissue engineered vascular graftsVascular graftsCongenital heart surgeryComputational fluid dynamics simulationsFluid dynamics simulationsPolytetrafluoroethylene graftHeart surgeryDystrophic calcificationRetrospective clinical studyGraft complianceDegree of calcificationClinical studiesProsthetic biomaterialsBiomaterialsAnimal modelsPolytetrafluoroethyleneHemodynamic performanceNatural historyCalcificationGraftOvine modelVascular conduitsLong-term successSurgeryChapter 25 Pharmacological treatments, mouse models, and the aorta
Humphrey J. Chapter 25 Pharmacological treatments, mouse models, and the aorta. 2024, 569-592. DOI: 10.1016/b978-0-323-95484-6.00021-x.Peer-Reviewed Original Research