2024
Steroid Profiling and Circadian Cortisol Secretion in Patients with Mild Autonomous Cortisol Secretion: A Cross-Sectional Study
Saini J, Singh S, Ebbehoj A, Zhang C, Nathani R, Fell V, Atkinson E, Achenbach S, Rivard A, Singh R, Grebe S, Bancos I. Steroid Profiling and Circadian Cortisol Secretion in Patients with Mild Autonomous Cortisol Secretion: A Cross-Sectional Study. The Journal Of Clinical Endocrinology & Metabolism 2024, dgae468. PMID: 38981002, DOI: 10.1210/clinem/dgae468.Peer-Reviewed Original ResearchAutonomous cortisol secretionUrine steroid metabolomeSteroid metabolomeReference subjectsCortisol secretionSteroid profileSteroid productionUrine steroid profileSubgroup of patientsArea under the curveHigh-resolution mass spectrometry assayCross-sectional studyCircadian cortisol secretionMass spectrometry assayAndrogen ratioFree cortisolSerum measurementsCircadian secretionPatientsMetabolomicsSteroidsSeparate daysUrineSecretionGlucocorticoid
2023
Gynecomastia in a Man With Adrenal Mass
Saini J, Navin P, Rivera M, Bancos I. Gynecomastia in a Man With Adrenal Mass. JCEM Case Reports 2023, 2: luad143. PMID: 38192879, PMCID: PMC10773200, DOI: 10.1210/jcemcr/luad143.Peer-Reviewed Original ResearchAdrenocortical carcinomaBilateral gynecomastiaEstrogen-secreting adrenal tumorRemoval of metastatic lesionsUltrasound-guided biopsyUrine steroid profileAdrenal malignancyDebulking surgeryLaparoscopic adrenalectomyAdrenal massAdrenal tumorsAdrenal insufficiencyMetastatic lesionsMultiple metastasesRare tumorInitial therapyMitotane therapyAdrenocortical adenomaEstrogen excessAndrogen precursorsEstrogen secretionGynecomastiaSurgical planningAndrogen metabolitesSteroid profile
2022
LBSAT59 Overnight Metyrapone Test And Urine Steroid Profiling In Patients Treated With Chronic Opioid Therapy: Prevalence Of Adrenal Insufficiency
Saini J, Gilliam W, Cunningham J, Thangamuthu K, Gruber L, Singh S, Sutor B, Hooten W, Bancos I. LBSAT59 Overnight Metyrapone Test And Urine Steroid Profiling In Patients Treated With Chronic Opioid Therapy: Prevalence Of Adrenal Insufficiency. Journal Of The Endocrine Society 2022, 6: a45-a46. PMCID: PMC9626924, DOI: 10.1210/jendso/bvac150.094.Peer-Reviewed Original ResearchOpioid-induced adrenal insufficiencyOvernight metyrapone testUrine steroid profileMetyrapone testExposure to opioidsDehydroepiandrosterone sulfateSteroid profileOpioid therapyAdrenal insufficiencyDiagnosis of adrenal disordersPrevalence of adrenal insufficiencyPatients treated with opioidsMorphine milligram equivalents (MME)/dayTreated with high dosesChronic opioid therapyMeasurement of ACTHDehydroepiandrosterone sulfate concentrationsCumulative opioid exposureQuality-of-life surveyChronic opioidsCross-sectional studyOpioid exposureAdrenal disordersSteroid metabolomeDaily MME