Emily Sharp, PhD, ABPP
Associate Professor of NeurologyCards
About
Research
Publications
Featured Publications
Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11C]UCB‐J
Mecca AP, O'Dell RS, Sharp ES, Banks ER, Bartlett HH, Zhao W, Lipior S, Diepenbrock NG, Chen M, Naganawa M, Toyonaga T, Nabulsi NB, Vander Wyk B, Arnsten AFT, Huang Y, Carson RE, van Dyck C. Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11C]UCB‐J. Alzheimer's & Dementia 2022, 18: 2527-2536. PMID: 35174954, PMCID: PMC9381645, DOI: 10.1002/alz.12582.Peer-Reviewed Original ResearchDesign and implementation of community consultation for research conducted under exception from informed consent regulations for the PreVent and the PreVent 2 trials: Changes over time and during the COVID-19 pandemic
Gugel T, Adams K, Baranoski M, Yanez N, Kampp M, Johnson T, Aydin A, Fajardo E, Sharp E, Potnis A, Johnson C, Treggiari M. Design and implementation of community consultation for research conducted under exception from informed consent regulations for the PreVent and the PreVent 2 trials: Changes over time and during the COVID-19 pandemic. Clinical Trials 2024, 21: 671-680. PMID: 38676438, PMCID: PMC11512686, DOI: 10.1177/17407745241243045.Peer-Reviewed Original ResearchSelf‐reported hearing loss is associated with faster cognitive and functional decline but not diagnostic conversion in the ADNI cohort
Miller A, Sharp E, Wang S, Zhao Y, Mecca A, van Dyck C, O'Dell R, Initiative F. Self‐reported hearing loss is associated with faster cognitive and functional decline but not diagnostic conversion in the ADNI cohort. Alzheimer's & Dementia 2024, 20: 7847-7858. PMID: 39324520, PMCID: PMC11567835, DOI: 10.1002/alz.14252.Peer-Reviewed Original ResearchHospital and long-term outcomes for subglottic suction and polyurethane cuff versus standard endotracheal tubes in emergency intubation (PreVent 2): a randomised controlled phase 2 trial
Treggiari M, Sharp E, Ohnuma T, Fajardo E, Aydin A, Akhtar S, Kampp M, Hashemaghaie M, Potnis A, Gugel T, Simon J, Curry L, Adams K, Darji B, Sureshanand S, Hintz R, Lorzano S, Johnson C, Yanez N. Hospital and long-term outcomes for subglottic suction and polyurethane cuff versus standard endotracheal tubes in emergency intubation (PreVent 2): a randomised controlled phase 2 trial. The Lancet Respiratory Medicine 2025, 14: 141-150. PMID: 41319662, PMCID: PMC12858053, DOI: 10.1016/s2213-2600(25)00294-2.Peer-Reviewed Original ResearchThis study investigates the long-term safety and efficacy of polyurethane-cuffed endotracheal tubes with subglottic suction in emergency intubation, showing no reduction in ventilator-associated pnemonia or improvement in patient outcomes, suggesting potential laryngeal injury risks.
2026
Person–Environment Transaction Underlying Personality Development in Middle and Late Adulthood
Beam C, Sharp E. Person–Environment Transaction Underlying Personality Development in Middle and Late Adulthood. Developmental Psychology 2026, 62: 1437-1455. PMID: 41609656, PMCID: PMC12857755, DOI: 10.1037/dev0002126.Peer-Reviewed Original Research
2019
Openness Declines in Advance of Death in Late Adulthood
Sharp ES, Beam CR, Reynolds CA, Gatz M. Openness Declines in Advance of Death in Late Adulthood. Psychology And Aging 2019, 34: 124-138. PMID: 30667240, PMCID: PMC6441733, DOI: 10.1037/pag0000328.Peer-Reviewed Original Research
2018
Effects of Normative Adjustments to the Montreal Cognitive Assessment
Pugh EA, Kemp EC, van Dyck CH, Mecca AP, Sharp ES, Initiative F. Effects of Normative Adjustments to the Montreal Cognitive Assessment. American Journal Of Geriatric Psychiatry 2018, 26: 1258-1267. PMID: 30314940, PMCID: PMC6779033, DOI: 10.1016/j.jagp.2018.09.009.Peer-Reviewed Original Research
2017
Personality predicts mortality risk: An integrative data analysis of 15 international longitudinal studies
Graham E, Rutsohn J, Turiano N, Bendayan R, Batterham P, Gerstorf D, Katz M, Reynolds C, Sharp E, Yoneda T, Bastarache E, Elleman L, Zelinski E, Johansson B, Kuh D, Barnes L, Bennett D, Deeg D, Lipton R, Pedersen N, Piccinin A, Spiro A, Muniz-Terrera G, Willis S, Schaie K, Roan C, Herd P, Hofer S, Mroczek D. Personality predicts mortality risk: An integrative data analysis of 15 international longitudinal studies. Journal Of Research In Personality 2017, 70: 174-186. PMID: 29230075, PMCID: PMC5722274, DOI: 10.1016/j.jrp.2017.07.005.Peer-Reviewed Original Research
2011
Relationship Between Education and Dementia
Sharp ES, Gatz M. Relationship Between Education and Dementia. Alzheimer Disease & Associated Disorders 2011, 25: 289-304. PMID: 21750453, PMCID: PMC3193875, DOI: 10.1097/wad.0b013e318211c83c.Peer-Reviewed Original Research
2010
Cognitive Engagement and Cognitive Aging: Is Openness Protective?
Sharp ES, Reynolds CA, Pedersen NL, Gatz M. Cognitive Engagement and Cognitive Aging: Is Openness Protective? Psychology And Aging 2010, 25: 60-73. PMID: 20230128, PMCID: PMC2853722, DOI: 10.1037/a0018748.Peer-Reviewed Original ResearchActivities of Daily LivingAgedAged, 80 and overAlzheimer DiseaseCardiovascular DiseasesCognition DisordersDiseases in TwinsEducational StatusExploratory BehaviorFemaleHumansInterpersonal RelationsLeisure ActivitiesLongitudinal StudiesMaleMiddle AgedModels, PsychologicalMotivationSocial BehaviorStatistics as TopicSurveys and QuestionnairesTemperament
Clinical Trials
Current Trials
Cognitive Training in Parkinson's Disease
IRB ID2000033352RoleSub InvestigatorPrimary Completion Date12/31/2027Recruiting ParticipantsGenderBothAge40+ years
Clinical Care
Overview
Emily Sharp, PhD, is a neuropsychologist at Yale Medicine with a specialty focus in memory disorders and Parkinson’s disease.
Dr. Sharp uses specialized neuropsychological measures to assess patients’ cognitive and emotional functioning, which provides neurologists and primary care physicians with important data for diagnosis and treatment planning.
“Neuropsychological testing allows us to see how a patient is doing within each domain of thinking, like memory, language, and attention. And those domains of thinking tend to correlate with different disorders. That can help the neurologist or referring provider better understand what’s going on,” she says.
Dr. Sharp spends several hours with patients, and interviews family members and caregivers, to form a complete picture of a patient’s current abilities. This information is then compiled into a detailed report with recommendations for the referring physician.
Dr. Sharp completed her PhD at the University of Southern California before finishing a two-year neuropsychology fellowship in Boston. Soon after, she joined Yale Medicine.
In addition to seeing patients, Dr. Sharp conducts research on the relationship between cognitive engagement and cognitive decline. She has a specific interest in interventions designed to identify, delay, and reduce the burden of cognitive impairment. She is a member of the clinical core faculty for the Yale Alzheimer’s Disease Research Center.
Clinical Specialties
Fact Sheets
Dementia
Learn More on Yale MedicineAlzheimer's Disease
Learn More on Yale Medicine
Board Certifications
Clinical Neuropsychology
- Certification Organization
- AB of Professional Psychology
- Original Certification Date
- 2017
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